| TARS Tarsus Pharmaceuticals Inc. | 8.26% | 2,254,797 | $124.8M | No change |
| AUPH Aurinia Pharmaceuticals Inc. | 5.01% | 8,429,500 | $75.7M | Add +16.6% |
| LKFT Lakefront Biotherapeutic-ADR filed as GALAPAGOS NV | 3.93% | 2,161,200 | $59.4M | Add +208.7% |
| EOLS Evolus Inc. | 3.65% | 4,997,399 | $55.2M | Add +3.1% |
| MIRM Mirum Pharmaceuticals Inc. | 3.38% | 1,237,107 | $51.2M | Reduce -3.9% |
| VRDN Viridian Therapeutics Inc. | 3.16% | 2,492,925 | $47.8M | Add +11.2% |
| IMCR Immunocore Holdings PLC-ADR | 3.04% | 1,555,600 | $45.9M | Add +40.7% |
| KALV Kalvista Pharmaceuticals Inc. | 2.74% | 4,893,847 | $41.5M | Add +13.2% |
| RLAY Relay Therapeutics Inc. | 2.20% | 8,068,058 | $33.2M | Add +126.1% |
| REPL Replimune Group Inc. | 2.16% | 2,700,000 | $32.7M | Add +125.0% |
| PTCT PTC Therapeutics Inc. | 2.09% | 700,000 | $31.6M | No change |
| BNTX Biontech SE-ADR | 2.04% | 270,000 | $30.8M | No change |
| ACAD Acadia Pharmaceuticals Inc. | 1.82% | 1,500,000 | $27.5M | No change |
| ITCI Intra-Cellular Therapies Inc. | 1.66% | 300,000 | $25.1M | No change |
| PCVX Vaxcyte Inc. | 1.62% | 300,000 | $24.6M | No change |
| DVAX Dynavax Technologies Corp. | 1.56% | 1,850,000 | $23.6M | Reduce -2.6% |
| LENZ Lenz Therapeutics Inc. | 1.47% | 766,940 | $22.1M | No change |
| NBIX Neurocrine Biosciences Inc. | 1.35% | 150,000 | $20.5M | No change |
| ALT Altimmune Inc. | 1.31% | 2,750,000 | $19.8M | No change |
| NVDA Nvidia Corp. | 1.27% | 142,569 | $19.1M | Reduce -3.5% |
| ANAB Anaptysbio Inc. | 1.17% | 1,330,879 | $17.6M | No change |
| ANIP Ani Pharmaceuticals Inc. | 1.16% | 317,500 | $17.6M | Reduce -29.4% |
| JAZZ Jazz Pharmaceuticals PLC | 1.14% | 140,000 | $17.2M | No change |
| ZYME Zymeworks Inc. | 1.07% | 1,100,000 | $16.1M | No change |
| AVIR Atea Pharmaceuticals Inc. | 1.06% | 4,788,912 | $16.0M | Add +4.0% |
| AVDL Avadel Pharmaceuticals Ltd. | 1.04% | 1,497,500 | $15.7M | Add +21.8% |
| META Meta Platforms Inc. Class A | 1.03% | 26,600 | $15.6M | Add +2.9% |
| LEGN Legend Biotech Corp.-ADR | 0.97% | 450,000 | $14.6M | New |
| GSK GSK PLC-Spon ADR | 0.90% | 400,000 | $13.5M | Reduce -11.1% |
| SNY Sanofi-ADR | 0.86% | 270,000 | $13.0M | Add +285.7% |
| LQDA Liquidia Corp. | 0.86% | 1,100,000 | $12.9M | Add +37.5% |
| VKTX Viking Therapeutics Inc. | 0.85% | 320,000 | $12.9M | Add +166.7% |
| TDOC Teladoc Health Inc. | 0.84% | 1,400,000 | $12.7M | No change |
| MRNA Moderna Inc. | 0.83% | 300,000 | $12.5M | New |
| KNSA Kiniksa Pharmaceuticals Inte | 0.82% | 628,609 | $12.4M | No change |
| HELP Cybin Inc. | 0.78% | 1,330,097 | $11.7M | Add +232.5% |
| VNDA Vanda Pharmaceuticals Inc. | 0.75% | 2,353,307 | $11.3M | No change |
| CGEM Cullinan Therapeutics Inc. | 0.74% | 921,138 | $11.2M | No change |
| CRSP Crispr Therapeutics AG | 0.69% | 266,500 | $10.5M | No change |
| NUVB Nuvation Bio Inc. | 0.69% | 3,900,000 | $10.4M | No change |
| HLVX Hillevax Inc. | 0.67% | 4,920,000 | $10.2M | No change |
| AZN Astrazeneca PLC-Spons ADR | 0.65% | 150,000 | $9.8M | No change |
| ELAN Elanco Animal Health Inc. | 0.64% | 800,000 | $9.7M | Add +33.3% |
| HRMY Harmony Biosciences Holdings | 0.64% | 281,200 | $9.7M | No change |
| ADMA Adma Biologics Inc. | 0.62% | 550,000 | $9.4M | New |
| RCKT Rocket Pharmaceuticals Inc. | 0.62% | 750,000 | $9.4M | No change |
| CRGX Cargo Therapeutics Inc. | 0.61% | 640,000 | $9.2M | Reduce -8.7% |
| DSGN Design Therapeutics Inc. | 0.60% | 1,480,975 | $9.1M | No change |
| CMPX Compass Therapeutics Inc. | 0.57% | 5,900,000 | $8.6M | Add +225.4% |
| BLCO Bausch + Lomb Corp. | 0.54% | 450,000 | $8.1M | Add +28.6% |
| EWTX Edgewise Therapeutics Inc. | 0.53% | 300,000 | $8.0M | New |
| ACET Adicet Bio Inc. | 0.52% | 8,145,988 | $7.8M | Reduce -0.9% |
| EPIX Essa Pharma Inc. | 0.51% | 4,300,000 | $7.7M | New |
| BIOA Bioage Labs Inc. | 0.51% | 1,318,361 | $7.6M | New |
| ABCL Abcellera Biologics Inc. | 0.50% | 2,582,816 | $7.6M | Add +12.3% |
| CTMX Cytomx Therapeutics Inc. | 0.50% | 7,311,760 | $7.5M | Reduce -6.4% |
| OMIC Singular Genomics Systems Inc. | 0.48% | 372,000 | $7.2M | No change |
| IBRX Immunitybio Inc. | 0.48% | 2,814,192 | $7.2M | New |
| INSM Insmed Inc. | 0.46% | 100,000 | $6.9M | No change |
| ONC Beone Medicines Ltd.-ADR filed as BEIGENE LTD | 0.45% | 37,000 | $6.8M | No change |
| VTYX Ventyx Biosciences Inc. | 0.45% | 3,100,000 | $6.8M | No change |
| DERM Journey Medical Corp. | 0.45% | 1,725,569 | $6.7M | New |
| BCRX Biocryst Pharmaceuticals Inc. | 0.40% | 800,000 | $6.0M | No change |
| DNTH Dianthus Therapeutics Inc. | 0.38% | 264,692 | $5.8M | No change |
| NKTX Nkarta Inc. | 0.38% | 2,293,719 | $5.7M | Add +252.9% |
| ALXO Alx Oncology Holdings Inc. | 0.36% | 3,296,883 | $5.5M | Reduce -21.6% |
| BIIB Biogen Inc. | 0.35% | 35,000 | $5.4M | No change |
| IONS Ionis Pharmaceuticals Inc. | 0.35% | 150,000 | $5.2M | No change |
| BHVN Biohaven Ltd. | 0.35% | 140,000 | $5.2M | No change |
| SEER Seer Inc. | 0.34% | 2,194,423 | $5.1M | Reduce -4.6% |
| CHRS Coherus Oncology Inc. | 0.33% | 3,650,000 | $5.0M | Add +55.3% |
| KZR Kezar Life Sciences Inc. | 0.32% | 720,000 | $4.8M | Add +97.8% |
| NVAX Novavax Inc. | 0.32% | 600,000 | $4.8M | Reduce -40.0% |
| ALMS Alumis Inc. | 0.31% | 600,000 | $4.7M | Add +40.6% |
| CYTK Cytokinetics Inc. | 0.31% | 100,000 | $4.7M | No change |
| APGE Apogee Therapeutics Inc. | 0.30% | 100,000 | $4.5M | No change |
| LNTH Lantheus Holdings Inc. | 0.30% | 50,000 | $4.5M | No change |
| BDTX Black Diamond Therapeutics I | 0.29% | 2,070,209 | $4.4M | Add +51.1% |
| RVMD Revolution Medicines Inc. | 0.29% | 100,000 | $4.4M | New |
| MRUS Merus NV | 0.28% | 100,000 | $4.2M | No change |
| PHAT Phathom Pharmaceuticals Inc. | 0.27% | 500,000 | $4.1M | New |
| NUVL Nuvalent Inc. Class A | 0.26% | 50,000 | $3.9M | No change |
| ARE Alexandria Real Estate Equit | 0.26% | 40,000 | $3.9M | No change |
| CMPS Compass Pathways PLC | 0.25% | 1,000,000 | $3.8M | New |
| IOVA Iovance Biotherapeutics Inc. | 0.24% | 500,000 | $3.7M | No change |
| TECX Tectonic Therapeutic Inc. | 0.24% | 79,166 | $3.7M | No change |
| GRAL Grail Inc. | 0.24% | 200,000 | $3.6M | New |
| STOK Stoke Therapeutics Inc. | 0.22% | 300,000 | $3.3M | New |
| HRTX Heron Therapeutics Inc. | 0.22% | 2,140,271 | $3.3M | Add +15.7% |
| CCCC C4 Therapeutics Inc. | 0.21% | 900,000 | $3.2M | Add +28.6% |
| FATE Fate Therapeutics Inc. | 0.20% | 1,855,954 | $3.1M | Add +165.1% |
| TGTX TG Therapeutics Inc. | 0.20% | 100,000 | $3.0M | No change |
| CRBP Corbus Pharmaceuticals Holdi | 0.19% | 242,653 | $2.9M | Reduce -59.6% |
| SWTX Springworks Therapeutics Inc. | 0.18% | 74,265 | $2.7M | No change |
| ELEV Elevation Oncology Inc. | 0.18% | 4,760,000 | $2.7M | No change |
| JANX Janux Therapeutics Inc. | 0.18% | 50,000 | $2.7M | New |
| DTIL Precision Biosciences Inc. | 0.17% | 673,332 | $2.6M | Add +8.0% |
| OKUR Onkure Therapeutics Inc. Class A | 0.17% | 294,626 | $2.5M | New |
| TBPH Theravance Biopharma Inc. | 0.16% | 262,896 | $2.5M | No change |
| ATYR Atyr Pharma Inc. | 0.16% | 671,134 | $2.4M | No change |
| SLNO Soleno Therapeutics Inc. | 0.15% | 50,000 | $2.2M | New |
| CDNA Caredx Inc. | 0.14% | 100,000 | $2.1M | New |
| GMAB Genmab A/S -SP ADR | 0.14% | 100,000 | $2.1M | No change |
| APLT Applied Therapeutics Inc. | 0.14% | 2,428,169 | $2.1M | Reduce -11.1% |
| IDXX Idexx Laboratories Inc. | 0.14% | 5,000 | $2.1M | New |
| BOLT Bolt Biotherapeutics Inc. | 0.14% | 3,812,773 | $2.0M | No change |
| FTRE Fortrea Holdings Inc. | 0.12% | 100,000 | $1.9M | New |
| ITOS Iteos Therapeutics Inc. | 0.11% | 221,716 | $1.7M | Reduce -90.8% |
| JPM JPMorgan Chase & Co. | 0.10% | 6,601 | $1.6M | Add +41.3% |
| WMT Walmart Inc. | 0.10% | 17,423 | $1.6M | Add +36.9% |
| THRD Third Harmonic Bio Inc. | 0.10% | 150,000 | $1.5M | New |
| ERAS Erasca Inc. | 0.10% | 602,915 | $1.5M | Add +19.9% |
| V Visa Inc. Class A | 0.10% | 4,718 | $1.5M | Add +42.2% |
| DIS The Walt Disney Co. filed as DISNEY WALT CO | 0.10% | 13,095 | $1.5M | Add +48.2% |
| MSFT Microsoft Corp. | 0.10% | 3,413 | $1.4M | Add +51.7% |
| REGN Regeneron Pharmaceuticals | 0.09% | 2,000 | $1.4M | New |
| VTRS Viatris Inc. | 0.09% | 114,316 | $1.4M | Add +54.7% |
| BRK.B Berkshire Hathaway Inc. Class B | 0.09% | 3,099 | $1.4M | Add +49.1% |
| VSTM Verastem Inc. | 0.09% | 270,000 | $1.4M | No change |
| MIND MEDICINE MINDMED INC | 0.09% | 200,000 | $1.4M | New |
| PYPL PayPal Holdings Inc. | 0.09% | 15,714 | $1.3M | Add +41.6% |
| PG The Procter & Gamble Co. | 0.09% | 7,962 | $1.3M | Add +54.8% |
| SNDX Syndax Pharmaceuticals Inc. | 0.09% | 100,000 | $1.3M | New |
| HD Home Depot Inc. | 0.09% | 3,353 | $1.3M | Add +42.4% |
| BEAM Beam Therapeutics Inc. | 0.08% | 50,000 | $1.2M | Reduce -70.6% |
| VZ Verizon Communications Inc. | 0.08% | 30,877 | $1.2M | Add +51.4% |
| TXN Texas Instruments Inc. | 0.08% | 6,568 | $1.2M | Add +56.3% |
| KO The Coca-Cola Co. | 0.08% | 19,714 | $1.2M | Add +59.3% |
| UAL United Airlines Holdings Inc. | 0.08% | 12,392 | $1.2M | Add +220.0% |
| NFLX Netflix Inc. | 0.08% | 1,344 | $1.2M | Add +214.8% |
| NKE Nike Inc. Class B | 0.08% | 15,789 | $1.2M | Add +65.5% |
| XOM Exxon Mobil Corp. | 0.08% | 11,053 | $1.2M | Add +57.8% |
| ULTA Ulta Beauty Inc. | 0.08% | 2,699 | $1.2M | New |
| UNH Unitedhealth Group Inc. | 0.08% | 2,308 | $1.2M | Add +62.3% |
| JNJ Johnson & Johnson | 0.08% | 7,959 | $1.2M | Add +58.7% |
| PFE Pfizer Inc. | 0.08% | 42,908 | $1.1M | Add +66.7% |
| AXP American Express Co. | 0.07% | 3,799 | $1.1M | Add +279.5% |
| INTC Intel Corp. | 0.07% | 55,997 | $1.1M | Add +53.1% |
| BA The Boeing Co. | 0.07% | 6,294 | $1.1M | New |
| AMZN Amazon.com Inc. | 0.07% | 5,071 | $1.1M | Add +335.6% |
| OPRX Optimizerx Corp. | 0.07% | 221,200 | $1.1M | New |
| OABI Omniab Inc. | 0.07% | 300,000 | $1.1M | No change |
| ALL Allstate Corp. | 0.07% | 5,319 | $1.0M | Add +322.1% |
| ATRA Atara Biotherapeutics Inc. | 0.07% | 75,196 | $1.0M | No change |
| HRL Hormel Foods Corp. | 0.07% | 31,741 | $996K | New |
| TMUS T-Mobile US Inc. | 0.07% | 4,509 | $995K | Add +321.0% |
| HPE Hewlett Packard Enterprise | 0.07% | 46,391 | $990K | New |
| GE General Electric filed as GE AEROSPACE | 0.07% | 5,911 | $986K | Add +327.4% |
| PAYX Paychex Inc. | 0.06% | 6,973 | $978K | New |
| CLX Clorox Company | 0.06% | 6,014 | $977K | Add +386.6% |
| MCD McDonald's Corp. | 0.06% | 3,365 | $975K | New |
| WHR Whirlpool Corp. | 0.06% | 8,510 | $974K | New |
| KRON Kronos Bio Inc. | 0.06% | 1,003,382 | $953K | New |
| SEE Sealed Air Corp. | 0.06% | 28,132 | $952K | New |
| FDX FedEx Corp. | 0.06% | 3,349 | $942K | New |
| SHW The Sherwin-Williams Co. | 0.06% | 2,765 | $940K | Add +351.8% |
| IPSC Century Therapeutics Inc. | 0.06% | 900,000 | $909K | No change |
| ATXS Astria Therapeutics Inc. | 0.06% | 100,000 | $894K | No change |
| GEV GE Vernova Inc. | 0.06% | 2,710 | $891K | New |
| MRNS Marinus Pharmaceuticals Inc. | 0.06% | 1,641,945 | $879K | Reduce -65.1% |
| KURA Kura Oncology Inc. | 0.06% | 100,000 | $871K | No change |
| CVX Chevron Corp. | 0.06% | 5,978 | $866K | New |
| PASG Passage Bio Inc. | 0.06% | 1,500,000 | $851K | No change |
| F Ford Motor Co. filed as FORD MTR CO | 0.06% | 85,749 | $849K | Add +571.3% |
| BCAB Bioatla Inc. | 0.05% | 1,374,076 | $812K | Add +57.2% |
| ENTA Enanta Pharmaceuticals Inc. | 0.05% | 126,655 | $728K | No change |
| LAB Standard Biotools Inc. | 0.05% | 407,755 | $714K | No change |
| MGNX Macrogenics Inc. | 0.05% | 218,856 | $711K | No change |
| LXRX Lexicon Pharmaceuticals Inc. | 0.04% | 850,268 | $628K | Add +750.3% |
| PBYI Puma Biotechnology Inc. | 0.04% | 200,000 | $610K | No change |
| NXTC Nextcure Inc. | 0.04% | 700,000 | $540K | Add +7.3% |
| EDIT Editas Medicine Inc. | 0.03% | 400,000 | $508K | New |
| ALLK Allakos LLC | 0.03% | 378,552 | $458K | Add +736.4% |
| AMLX Amylyx Pharmaceuticals Inc. | 0.03% | 100,000 | $378K | No change |
| TCRX Tscan Therapeutics Inc. | 0.02% | 117,847 | $358K | New |
| ATHIRA PHARMA INC | 0.02% | 600,000 | $352K | No change |
| OTLK Outlook Therapeutics Inc. | 0.02% | 182,502 | $345K | Reduce -88.3% |
| REVIVA PHARMACEUTCLS HLDGS I | 0.02% | 170,000 | $308K | New |
| ALLOVIR INC | 0.02% | 552,264 | $232K | New |
| AFMDQ Affimed NV | 0.01% | 148,315 | $176K | No change |
| IVVD Invivyd Inc. | 0.01% | 330,172 | $146K | No change |
| RLMD Relmada Therapeutics Inc. | 0.01% | 200,825 | $104K | Add +295.1% |
| IMRX Immuneering Corp. Class A | 0.00% | 12,073 | $27K | New |