Agios PharmaceuticalsAGIO
13F holders, Q4 2025 (December 31)238holders +17
57new positions
44sold out
6famous investors
$27.22avg. 13F price*
At the end of Q4 2025, 238 institutions reported holding Agios Pharmaceuticals Inc. (AGIO) in their 13F filings, up 17 from Q3 2025. 57 opened new positions and 44 sold out. The largest holders were Vanguard Group Inc. ($152.3M), BlackRock, Inc. ($142.5M) and Farallon Capital Management, L.L.C. ($140.4M). 6 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Agios Pharmaceuticals Inc.
- CUSIP
- 00847X104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 57 | $169.3M |
| Exits | 44 | $598.3M |
All 13F filers, Q3 2025 → Q4 2025: 17,844,236 shares bought and 21,695,100 shares sold, net −3,850,864 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 238 holders
| Vanguard Group Inc. | 0.00% | Reduce -0.2% | 5,594,353 | $152.3M |
| BlackRock, Inc. | 0.00% | Add +15.2% | 5,235,429 | $142.5M |
| Farallon Capital Management, L.L.C. | 0.73% | Reduce -10.8% | 5,159,505 | $140.4M |
| State Street Corp. | 0.00% | Add +37.4% | 3,108,145 | $84.6M |
| Armistice Capital, LLC | 2.03% | Add +297.4% | 3,036,000 | $82.6M |
| Erste Asset Management GmbH | 0.64% | Add +1.4% | 2,804,900 | $76.3M |
| D. E. Shaw & Co. | 0.04% | Add +399.6% | 1,837,186 | $50.0M |
| Nomura Asset Management International Inc. | 0.07% | — | 1,701,409 | $46.3M |
| Geode Capital Management, LLC | 0.00% | Reduce -0.2% | 1,413,538 | $38.5M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.04% | Add +37.8% | 1,360,730 | $37.0M |
| Citadel Advisors | 0.03% | Add +174.2% | 1,348,968 | $36.7M |
| MPM Bioimpact LLC | 4.06% | New | 1,303,373 | $35.5M |
| Frazier Life Sciences Management, L.P. | 0.94% | No change | 1,279,754 | $34.8M |
| GW&K Investment Management, LLC | 0.28% | Add +41.5% | 1,207,301 | $32.9M |
| TCG Crossover Management, LLC | 1.06% | Reduce -17.4% | 1,181,841 | $32.2M |
| Susquehanna International Group, LLP | 0.04% | New | 1,142,432 | $31.1M |
| Jane Street Group, LLC | 0.04% | Add +183.7% | 1,121,050 | $30.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +28.5% | 1,033,974 | $28.1M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -1.6% | 1,004,341 | $27.3M |
| Morgan Stanley | 0.00% | Add +114.4% | 894,037 | $24.3M |
| Rock Springs Capital Management LP | 1.12% | Reduce -16.6% | 799,163 | $21.8M |
| Capital International Investors | 0.00% | New | 703,865 | $19.2M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -61.5% | 637,886 | $17.4M |
| Balyasny Asset Management L.P. | 0.03% | Add +28.2% | 635,069 | $17.3M |
| SCS Capital Management LLC | 0.17% | No change | 598,765 | $16.3M |
| Wellington Management Group LLP | 0.00% | Reduce -75.8% | 597,826 | $16.3M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.04% | Add +6.1% | 562,642 | $15.3M |
| Bank of America Corp. | 0.00% | Reduce -52.3% | 539,341 | $14.7M |
| Foresite Capital Management VI LLC | 4.36% | New | 530,000 | $14.4M |
| Northern Trust Corp. | 0.00% | Reduce -7.8% | 511,901 | $13.9M |
| Artisan Partners Limited Partnership | 0.02% | Add +25.2% | 504,485 | $13.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.1% | 482,622 | $13.1M |
| ArrowMark Colorado Holdings LLC | 0.28% | Reduce -31.4% | 466,151 | $12.7M |
| Algert Global LLC | 0.18% | Add +1058.0% | 414,218 | $11.3M |
| Millennium Management | 0.01% | Add +7788.0% | 398,267 | $10.8M |
| Qube Research & Technologies Ltd | 0.01% | New | 378,373 | $10.3M |
| Marshall Wace, LLP | 0.01% | Add +55.9% | 353,639 | $9.6M |
| Legal & General Group Plc | 0.00% | Add +1.6% | 328,211 | $8.9M |
| Vestal Point Capital, LP | 0.32% | Add +155.9% | 325,000 | $8.8M |
| Barclays PLC | 0.00% | Add +48.3% | 320,352 | $8.7M |
| Two Sigma Investments, LP | 0.01% | Add +403.4% | 300,156 | $8.2M |
| Nuveen, LLC | 0.00% | Add +149.1% | 297,908 | $8.1M |
| JPMorgan Chase & Co. | 0.00% | Add +37.5% | 251,777 | $6.9M |
| BNP Paribas Financial Markets | 0.00% | Add +1551.0% | 242,670 | $6.6M |
| Trexquant Investment LP | 0.06% | New | 226,600 | $6.2M |
| Palo Alto Investors LP | 0.81% | Reduce -20.0% | 212,499 | $5.8M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -24.7% | 205,019 | $5.6M |
| Point72 Asset Management | 0.01% | Add +2973.6% | 200,000 | $5.4M |
| Bank of New York Mellon Corp | 0.00% | Reduce -27.1% | 196,893 | $5.4M |
| ADAR1 Capital Management, LLC | 0.38% | Add +408.1% | 188,000 | $5.1M |
| Edgestream Partners, L.P. | 0.13% | New | 167,998 | $4.6M |
| Group One Trading LLC | 0.13% | New | 166,614 | $4.5M |
| Tetragon Partners GP Ltd | 0.93% | New | 162,018 | $4.4M |
| American Century Companies Inc. | 0.00% | Add +4.4% | 151,486 | $4.1M |
| Moore Capital Management, LP | 0.09% | Add +172.7% | 150,000 | $4.1M |
| Allianz Asset Management GmbH | 0.00% | Add +0.9% | 147,950 | $4.0M |
| HighVista Strategies LLC | 1.04% | Reduce -24.4% | 147,662 | $4.0M |
| HRT Financial LP | 0.01% | New | 146,469 | $4.0M |
| Invesco Ltd. | 0.00% | Add +12.3% | 142,580 | $3.9M |
| Exome Asset Management LLC | 1.84% | New | 136,942 | $3.7M |
| UBS Group AG | 0.00% | Reduce -47.8% | 126,665 | $3.4M |
| Deutsche Bank AG | 0.00% | Reduce -86.7% | 122,875 | $3.3M |
| Squarepoint Ops LLC | 0.01% | New | 121,763 | $3.3M |
| Ikarian Capital, LLC | 0.41% | Reduce -9.1% | 115,489 | $3.1M |
| Jacobs Levy Equity Management, Inc. | 0.01% | New | 111,150 | $3.0M |
| Assenagon Asset Management S.A. | 0.00% | Add +64.5% | 110,440 | $3.0M |
| Swiss National Bank | 0.00% | Add +2.1% | 108,860 | $3.0M |
| Rafferty Asset Management, LLC | 0.01% | Add +57.6% | 107,490 | $2.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.1% | 106,996 | $2.9M |
| Hudson Bay Capital Management LP | 0.02% | Reduce -18.4% | 100,000 | $2.7M |
| Parkman Healthcare Partners LLC | 0.26% | Reduce -0.8% | 99,604 | $2.7M |
| Caption Management, LLC | 0.12% | Add +434.4% | 93,486 | $2.5M |
| Citigroup Inc. | 0.00% | Add +102.3% | 88,238 | $2.4M |
| Two Sigma Advisers, LP | 0.00% | Add +526.5% | 85,200 | $2.3M |
| Prudential Financial Inc. | 0.00% | Reduce -17.5% | 81,055 | $2.2M |
| Panagora Asset Management Inc. | 0.01% | New | 79,840 | $2.2M |
| Y-Intercept (Hong Kong) Ltd | 0.05% | Add +906.4% | 79,831 | $2.2M |
| Lynx1 Capital Management LP | 0.44% | New | 79,624 | $2.2M |
| First Trust Advisors LP | 0.00% | Add +5.7% | 78,656 | $2.1M |
| Woodline Partners LP | 0.01% | Add +0.6% | 74,423 | $2.0M |
| Rhumbline Advisers | 0.00% | Reduce -15.4% | 74,153 | $2.0M |
| ExodusPoint Capital Management, LP | 0.02% | New | 71,146 | $1.9M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -26.8% | 70,256 | $1.9M |
| Kennedy Capital Management LLC | 0.04% | Add +166.4% | 65,655 | $1.8M |
| Wells Fargo & Company | 0.00% | Add +44.7% | 64,772 | $1.8M |
| Alliancebernstein L.P. | 0.00% | Reduce -0.0% | 61,494 | $1.7M |
| Tudor Investment Corporation | 0.01% | New | 61,345 | $1.7M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Reduce -15.0% | 60,560 | $1.6M |
| TD Asset Management Inc | 0.00% | Reduce -55.3% | 57,292 | $1.6M |
| California State Teachers Retirement System | 0.00% | Reduce -13.1% | 53,239 | $1.4M |
| Headlands Technologies LLC | 0.12% | New | 52,739 | $1.4M |
| New York State Common Retirement Fund | 0.00% | Add +3.9% | 51,707 | $1.4M |
| Engineers Gate Manager LP | 0.02% | New | 49,128 | $1.3M |
| Alps Advisors Inc. | 0.01% | Add +73.8% | 47,881 | $1.3M |
| State of New Jersey Common Pension Fund D | 0.00% | New | 47,414 | $1.3M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 40,000 | $1.3M |
| SG Americas Securities, LLC | 0.00% | Add +68.0% | 46,451 | $1.3M |
| Schroder Investment Management Group | 0.00% | New | 46,242 | $1.3M |
| XTX Topco Ltd | 0.03% | New | 46,039 | $1.3M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Add +0.7% | 41,361 | $1.1M |
"% of holder's portfolio" is AGIO's weight in each manager's 13F, not the share of Agios Pharmaceuticals Inc. the manager owns.