Agios PharmaceuticalsAGIO
13F holders, Q4 2025 (December 31)238holders +17
57new positions
44sold out
6famous investors
$27.22avg. 13F price*
At the end of Q4 2025, 238 institutions reported holding Agios Pharmaceuticals Inc. (AGIO) in their 13F filings, up 17 from Q3 2025. 57 opened new positions and 44 sold out. The largest holders were Vanguard Group Inc. ($152.3M), BlackRock, Inc. ($142.5M) and Farallon Capital Management, L.L.C. ($140.4M). 6 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Agios Pharmaceuticals Inc.
- CUSIP
- 00847X104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 57 | $169.3M |
| Exits | 44 | $598.3M |
All 13F filers, Q3 2025 → Q4 2025: 17,844,236 shares bought and 21,695,100 shares sold, net −3,850,864 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 238 holders
| Vanguard Group Inc. | 0.00% | Reduce -0.2% | 5,594,353 | $152.3M |
| BlackRock, Inc. | 0.00% | Add +15.2% | 5,235,429 | $142.5M |
| Farallon Capital Management, L.L.C. | 0.73% | Reduce -10.8% | 5,159,505 | $140.4M |
| State Street Corp. | 0.00% | Add +37.4% | 3,108,145 | $84.6M |
| Armistice Capital, LLC | 2.03% | Add +297.4% | 3,036,000 | $82.6M |
| Erste Asset Management GmbH | 0.64% | Add +1.4% | 2,804,900 | $76.3M |
| D. E. Shaw & Co. | 0.04% | Add +399.6% | 1,837,186 | $50.0M |
| Nomura Asset Management International Inc. | 0.07% | — | 1,701,409 | $46.3M |
| Geode Capital Management, LLC | 0.00% | Reduce -0.2% | 1,413,538 | $38.5M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.04% | Add +37.8% | 1,360,730 | $37.0M |
| Citadel Advisors | 0.03% | Add +174.2% | 1,348,968 | $36.7M |
| MPM Bioimpact LLC | 4.06% | New | 1,303,373 | $35.5M |
| Frazier Life Sciences Management, L.P. | 0.94% | No change | 1,279,754 | $34.8M |
| GW&K Investment Management, LLC | 0.28% | Add +41.5% | 1,207,301 | $32.9M |
| TCG Crossover Management, LLC | 1.06% | Reduce -17.4% | 1,181,841 | $32.2M |
| Susquehanna International Group, LLP | 0.04% | New | 1,142,432 | $31.1M |
| Jane Street Group, LLC | 0.04% | Add +183.7% | 1,121,050 | $30.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +28.5% | 1,033,974 | $28.1M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -1.6% | 1,004,341 | $27.3M |
| Morgan Stanley | 0.00% | Add +114.4% | 894,037 | $24.3M |
| Rock Springs Capital Management LP | 1.12% | Reduce -16.6% | 799,163 | $21.8M |
| Capital International Investors | 0.00% | New | 703,865 | $19.2M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -61.5% | 637,886 | $17.4M |
| Balyasny Asset Management L.P. | 0.03% | Add +28.2% | 635,069 | $17.3M |
| SCS Capital Management LLC | 0.17% | No change | 598,765 | $16.3M |
| Wellington Management Group LLP | 0.00% | Reduce -75.8% | 597,826 | $16.3M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.04% | Add +6.1% | 562,642 | $15.3M |
| Bank of America Corp. | 0.00% | Reduce -52.3% | 539,341 | $14.7M |
| Foresite Capital Management VI LLC | 4.36% | New | 530,000 | $14.4M |
| Northern Trust Corp. | 0.00% | Reduce -7.8% | 511,901 | $13.9M |
| Artisan Partners Limited Partnership | 0.02% | Add +25.2% | 504,485 | $13.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.1% | 482,622 | $13.1M |
| ArrowMark Colorado Holdings LLC | 0.28% | Reduce -31.4% | 466,151 | $12.7M |
| Algert Global LLC | 0.18% | Add +1058.0% | 414,218 | $11.3M |
| Millennium Management | 0.01% | Add +7788.0% | 398,267 | $10.8M |
| Qube Research & Technologies Ltd | 0.01% | New | 378,373 | $10.3M |
| Marshall Wace, LLP | 0.01% | Add +55.9% | 353,639 | $9.6M |
| Legal & General Group Plc | 0.00% | Add +1.6% | 328,211 | $8.9M |
| Vestal Point Capital, LP | 0.32% | Add +155.9% | 325,000 | $8.8M |
| Barclays PLC | 0.00% | Add +48.3% | 320,352 | $8.7M |
| Two Sigma Investments, LP | 0.01% | Add +403.4% | 300,156 | $8.2M |
| Nuveen, LLC | 0.00% | Add +149.1% | 297,908 | $8.1M |
| JPMorgan Chase & Co. | 0.00% | Add +37.5% | 251,777 | $6.9M |
| BNP Paribas Financial Markets | 0.00% | Add +1551.0% | 242,670 | $6.6M |
| Trexquant Investment LP | 0.06% | New | 226,600 | $6.2M |
| Palo Alto Investors LP | 0.81% | Reduce -20.0% | 212,499 | $5.8M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -24.7% | 205,019 | $5.6M |
| Point72 Asset Management | 0.01% | Add +2973.6% | 200,000 | $5.4M |
| Bank of New York Mellon Corp | 0.00% | Reduce -27.1% | 196,893 | $5.4M |
| ADAR1 Capital Management, LLC | 0.38% | Add +408.1% | 188,000 | $5.1M |
| Edgestream Partners, L.P. | 0.13% | New | 167,998 | $4.6M |
| Group One Trading LLC | 0.13% | New | 166,614 | $4.5M |
| Tetragon Partners GP Ltd | 0.93% | New | 162,018 | $4.4M |
| American Century Companies Inc. | 0.00% | Add +4.4% | 151,486 | $4.1M |
| Moore Capital Management, LP | 0.09% | Add +172.7% | 150,000 | $4.1M |
| Allianz Asset Management GmbH | 0.00% | Add +0.9% | 147,950 | $4.0M |
| HighVista Strategies LLC | 1.04% | Reduce -24.4% | 147,662 | $4.0M |
| HRT Financial LP | 0.01% | New | 146,469 | $4.0M |
| Invesco Ltd. | 0.00% | Add +12.3% | 142,580 | $3.9M |
| Exome Asset Management LLC | 1.84% | New | 136,942 | $3.7M |
| UBS Group AG | 0.00% | Reduce -47.8% | 126,665 | $3.4M |
| Deutsche Bank AG | 0.00% | Reduce -86.7% | 122,875 | $3.3M |
| Squarepoint Ops LLC | 0.01% | New | 121,763 | $3.3M |
| Ikarian Capital, LLC | 0.41% | Reduce -9.1% | 115,489 | $3.1M |
| Jacobs Levy Equity Management, Inc. | 0.01% | New | 111,150 | $3.0M |
| Assenagon Asset Management S.A. | 0.00% | Add +64.5% | 110,440 | $3.0M |
| Swiss National Bank | 0.00% | Add +2.1% | 108,860 | $3.0M |
| Rafferty Asset Management, LLC | 0.01% | Add +57.6% | 107,490 | $2.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.1% | 106,996 | $2.9M |
| Hudson Bay Capital Management LP | 0.02% | Reduce -18.4% | 100,000 | $2.7M |
| Parkman Healthcare Partners LLC | 0.26% | Reduce -0.8% | 99,604 | $2.7M |
| Caption Management, LLC | 0.12% | Add +434.4% | 93,486 | $2.5M |
| Citigroup Inc. | 0.00% | Add +102.3% | 88,238 | $2.4M |
| Two Sigma Advisers, LP | 0.00% | Add +526.5% | 85,200 | $2.3M |
| Prudential Financial Inc. | 0.00% | Reduce -17.5% | 81,055 | $2.2M |
| Panagora Asset Management Inc. | 0.01% | New | 79,840 | $2.2M |
| Y-Intercept (Hong Kong) Ltd | 0.05% | Add +906.4% | 79,831 | $2.2M |
| Lynx1 Capital Management LP | 0.44% | New | 79,624 | $2.2M |
| First Trust Advisors LP | 0.00% | Add +5.7% | 78,656 | $2.1M |
| Woodline Partners LP | 0.01% | Add +0.6% | 74,423 | $2.0M |
| Rhumbline Advisers | 0.00% | Reduce -15.4% | 74,153 | $2.0M |
| ExodusPoint Capital Management, LP | 0.02% | New | 71,146 | $1.9M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -26.8% | 70,256 | $1.9M |
| Kennedy Capital Management LLC | 0.04% | Add +166.4% | 65,655 | $1.8M |
| Wells Fargo & Company | 0.00% | Add +44.7% | 64,772 | $1.8M |
| Alliancebernstein L.P. | 0.00% | Reduce -0.0% | 61,494 | $1.7M |
| Tudor Investment Corporation | 0.01% | New | 61,345 | $1.7M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Reduce -15.0% | 60,560 | $1.6M |
| TD Asset Management Inc | 0.00% | Reduce -55.3% | 57,292 | $1.6M |
| California State Teachers Retirement System | 0.00% | Reduce -13.1% | 53,239 | $1.4M |
| Headlands Technologies LLC | 0.12% | New | 52,739 | $1.4M |
| New York State Common Retirement Fund | 0.00% | Add +3.9% | 51,707 | $1.4M |
| Engineers Gate Manager LP | 0.02% | New | 49,128 | $1.3M |
| Alps Advisors Inc. | 0.01% | Add +73.8% | 47,881 | $1.3M |
| State of New Jersey Common Pension Fund D | 0.00% | New | 47,414 | $1.3M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 40,000 | $1.3M |
| SG Americas Securities, LLC | 0.00% | Add +68.0% | 46,451 | $1.3M |
| Schroder Investment Management Group | 0.00% | New | 46,242 | $1.3M |
| XTX Topco Ltd | 0.03% | New | 46,039 | $1.3M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Add +0.7% | 41,361 | $1.1M |
| Freestone Grove Partners LP | 0.01% | Add +164.8% | 40,841 | $1.1M |
| Profund Advisors LLC | 0.03% | Add +163.8% | 39,850 | $1.1M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +7.8% | 39,455 | $1.1M |
| Boothbay Fund Management, LLC | 0.03% | Reduce -92.5% | 37,291 | $1.0M |
| Harbor Capital Advisors, Inc. | 0.08% | Add +6.9% | 37,228 | $1.0M |
| Aquatic Capital Management LLC | 0.03% | New | 36,006 | $980K |
| Quadrature Capital Ltd | 0.01% | New | 35,857 | $976K |
| Capital Fund Management S.A. | 0.01% | New | 35,788 | $974K |
| Edgewood Management LLC | 0.00% | No change | 35,000 | $953K |
| State of Wisconsin Investment Board | 0.00% | Reduce -2.6% | 34,637 | $943K |
| Prelude Capital Management, LLC | 0.07% | New | 33,685 | $917K |
| Hennion & Walsh Asset Management, Inc. | 0.03% | Add +31.3% | 33,470 | $911K |
| Jump Financial, LLC | 0.01% | Reduce -62.4% | 33,052 | $900K |
| MetLife Investment Management, LLC | 0.00% | Reduce -5.3% | 32,217 | $877K |
| Seven Fleet Capital Management LP | 0.58% | — | 31,738 | $864K |
| Ishara Investments LP | 0.95% | — | 30,000 | $817K |
| Intech Investment Management LLC | 0.01% | Add +18.0% | 27,827 | $757K |
| AQR Capital Management | 0.00% | Reduce -69.5% | 27,926 | $754K |
| Victory Capital Management Inc. | 0.00% | Reduce -8.4% | 27,697 | $754K |
| Quantinno Capital Management LP | 0.00% | New | 26,855 | $731K |
| Aigen Investment Management, LP | 0.16% | New | 25,915 | $705K |
| Virtus Investment Advisers, LLC | 0.19% | Add +94.5% | 25,060 | $682K |
| Federated Hermes, Inc. | 0.00% | Add +47173.6% | 25,055 | $682K |
| Russell Investments Group, Ltd. | 0.00% | Add +260.0% | 24,679 | $672K |
| FMR LLC | 0.00% | Add +17.5% | 24,334 | $662K |
| Janus Henderson Group PLC | 0.00% | No change | 23,797 | $648K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +15.3% | 23,620 | $643K |
| Rockefeller Capital Management L.P. | 0.00% | Add +31.4% | 21,071 | $574K |
| Oak Ridge Investments LLC | 0.03% | Reduce -21.2% | 20,004 | $545K |
| Brevan Howard Capital Management LP | 0.01% | Add +60.2% | 19,336 | $526K |
| Handelsbanken Fonder AB | 0.00% | No change | 19,323 | $526K |
| Entropy Technologies, LP | 0.03% | New | 19,163 | $522K |
| VARCOV Co. | 0.21% | — | 19,104 | $520K |
| Canada Pension Plan Investment Board | 0.00% | New | 18,200 | $495K |
| Knott David M Jr | 0.23% | New | 18,000 | $490K |
| Inspire Investing, LLC | 0.04% | Add +50.2% | 17,115 | $466K |
| WINTON GROUP Ltd | 0.02% | Add +2.1% | 16,751 | $456K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,847 | $431K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +0.0% | 15,640 | $426K |
| Arizona State Retirement System | 0.00% | Reduce -5.7% | 15,330 | $417K |
| Sei Investments Co. | 0.00% | Reduce -55.6% | 14,352 | $391K |
| Tidal Investments LLC | 0.00% | Reduce -4.5% | 14,247 | $388K |
| Atria Investments, Inc | 0.00% | Add +5.0% | 14,053 | $383K |
| AlphaCentric Advisors LLC | 0.36% | — | 13,141 | $358K |
| Royal Bank of Canada | 0.00% | Reduce -25.5% | 13,055 | $354K |
| ProShare Advisors LLC | 0.00% | Add +10.0% | 12,897 | $351K |
| Envestnet Asset Management Inc. | 0.00% | Add +35.1% | 12,735 | $347K |
| Commerce Bank | 0.00% | Add +38.2% | 12,656 | $344K |
| Bridgefront Capital, LLC | 0.09% | New | 12,649 | $344K |
| Fox Run Management, L.L.C. | 0.05% | New | 12,567 | $342K |
| Nomura Holdings Inc. | 0.00% | New | 12,355 | $336K |
| AlphaQuest LLC | 0.02% | Add +121.1% | 11,963 | $326K |
| Pale Fire Capital SE | 0.04% | New | 11,850 | $323K |
| KLP Kapitalforvaltning As | 0.00% | No change | 11,800 | $321K |
| Gallagher Fiduciary Advisors, LLC | 0.01% | Reduce -0.1% | 11,245 | $306K |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -48.6% | 10,437 | $284K |
| Creative Planning | 0.00% | Reduce -20.9% | 10,370 | $282K |
| Capstone Investment Advisors, LLC | 0.00% | New | 10,355 | $282K |
| Voya Investment Management LLC | 0.00% | No change | 10,134 | $276K |
| STRS Ohio | 0.00% | New | 10,000 | $272K |
| China Universal Asset Management Co., Ltd. | 0.02% | Reduce -6.7% | 9,502 | $259K |
| Two Sigma Securities, LLC | 0.03% | New | 9,198 | $250K |
| Diversified Trust Co. | 0.00% | New | 9,162 | $249K |
| Inscription Capital, LLC | 0.02% | New | 8,595 | $234K |
| Fiduciary Trust Co | 0.00% | Add +51.2% | 8,247 | $224K |
| Campbell & CO Investment Adviser LLC | 0.01% | New | 8,226 | $224K |
| Teacher Retirement System of Texas | 0.00% | Reduce -39.4% | 8,167 | $222K |
| Griffin Asset Management, Inc. | 0.02% | New | 7,382 | $201K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,796 | $185K |
| Caitong International Asset Management Co., Ltd | 0.04% | New | 6,740 | $183K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +388.9% | 6,634 | $181K |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -47.9% | 6,570 | $179K |
| Simplex Trading, LLC | 0.00% | New | 6,209 | $169K |
| Contravisory Investment Management, Inc. | 0.03% | New | 6,189 | $168K |
| State of Alaska, Department of Revenue | 0.00% | New | 5,000 | $136K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 4,719 | $128K |
| PNC Financial Services Group, Inc. | 0.00% | Add +3.4% | 4,710 | $128K |
| Sterling Capital Management LLC | 0.00% | Reduce -16.1% | 3,283 | $89K |
| First Horizon Corp. | 0.00% | Add +175.4% | 3,095 | $84K |
| KBC Group NV | 0.00% | Add +72.5% | 3,020 | $82K |
| Quarry LP | 0.01% | Reduce -40.0% | 3,000 | $82K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +26.2% | 2,834 | $77K |
| Eurizon Capital SGR S.p.A. | 0.00% | — | 2,647 | $72K |
| Amalgamated Bank | 0.00% | Reduce -9.3% | 1,774 | $48K |
| Osaic Holdings, Inc. | 0.00% | Add +419.9% | 1,747 | $48K |
| Assetmark, Inc. | 0.00% | Add +37.9% | 1,317 | $36K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -8.4% | 1,145 | $31K |
| T. Rowe Price Investment Management, Inc. | 0.00% | New | 892 | $25K |
| Torren Management, LLC | 0.01% | — | 615 | $17K |
| US Bancorp \de | 0.00% | Reduce -10.5% | 509 | $14K |
| City Holding Co. | 0.00% | New | 500 | $14K |
| Hurley Capital, LLC | 0.01% | Add +32.8% | 486 | $13K |
| Cwm, LLC | 0.00% | Reduce -89.9% | 484 | $13K |
| Los Angeles Capital Management LLC | 0.00% | New | 300 | $13K |
| Smartleaf Asset Management LLC | 0.00% | Add +15.6% | 460 | $13K |
| Signaturefd, LLC | 0.00% | Reduce -22.2% | 399 | $11K |
| Quantbot Technologies LP | 0.00% | Reduce -80.5% | 386 | $11K |
| Aspect Partners, LLC | 0.00% | No change | 361 | $10K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -62.2% | 295 | $8K |
| Bell Investment Advisors, Inc | 0.00% | Reduce -5.7% | 281 | $8K |
| Thurston, Springer, Miller, Herd & Titak, Inc. | 0.00% | New | 241 | $7K |
| Daiwa Securities Group Inc. | 0.00% | No change | 204 | $6K |
| Comerica Bank | 0.00% | Reduce -44.1% | 209 | $6K |
| Concord Wealth Partners | 0.00% | No change | 200 | $5K |
| Hillsdale Investment Management Inc. | 0.00% | No change | 200 | $5K |
| GAMMA Investing LLC | 0.00% | Reduce -17.0% | 171 | $5K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -6.2% | 151 | $4K |
| Brown Brothers Harriman & Co. | 0.00% | New | 144 | $4K |
| Triumph Capital Management | 0.00% | New | 100 | $3K |
| Versant Capital Management, Inc | 0.00% | Reduce -70.9% | 92 | $3K |
| Private Wealth Management Group, LLC | 0.00% | Reduce -1.2% | 83 | $2K |
| Arax Advisory Partners | 0.00% | Reduce -88.8% | 79 | $2K |
| Bessemer Group Inc. | 0.00% | Reduce -59.1% | 76 | $2K |
| Root Financial Partners, LLC | 0.00% | Reduce -37.7% | 66 | $2K |
| Pinnacle Wealth Planning Services, Inc. | 0.00% | New | 40 | $1K |
| Covestor Ltd | 0.00% | Reduce -35.9% | 41 | $1K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -45.2% | 34 | $926 |
| Raffa Wealth Management, LLC | 0.00% | No change | 32 | $871 |
| Keating Financial Advisory Services, Inc. | 0.00% | — | 21 | $572 |
| Manchester Capital Management LLC | 0.00% | New | 16 | $436 |
| Quadrant Capital Group LLC | 0.00% | No change | 16 | $436 |
| Parkside Financial Bank & Trust | 0.00% | Reduce -66.7% | 15 | $409 |
| Parallel Advisors, LLC | 0.00% | No change | 12 | $327 |
| Allworth Financial LP | 0.00% | Reduce -35.3% | 11 | $300 |
| Global Retirement Partners, LLC | 0.00% | New | 11 | $299 |
| SageView Advisory Group, LLC | 0.00% | New | 10 | $273 |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 9 | $245 |
| IFP Advisors, Inc | 0.00% | No change | 6 | $163 |
| Rothschild Investment LLC | 0.00% | Reduce -93.3% | 5 | $136 |
| Fortitude Family Office, LLC | 0.00% | No change | 5 | $136 |
| Essential Partners LLC | 0.00% | Reduce -95.7% | 5 | $136 |
| JFS Wealth Advisors, LLC | 0.00% | Reduce -75.0% | 4 | $109 |
| SBI Securities Co., Ltd. | 0.00% | No change | 4 | $109 |
| Bay Harbor Wealth Management, LLC | 0.00% | Add +33.3% | 4 | $108 |
| Rialto Wealth Management, LLC | 0.00% | No change | 2 | $55 |
| Dunhill Financial, LLC | 0.00% | New | 2 | $50 |
| SJS Investment Consulting Inc. | 0.00% | Reduce -50.0% | 1 | $28 |
| Jones Financial Companies LLLP | 0.00% | No change | 1 | $27 |
"% of holder's portfolio" is AGIO's weight in each manager's 13F, not the share of Agios Pharmaceuticals Inc. the manager owns.