AlectorALEC
13F holders, Q3 2025 (September 30)At the end of Q3 2025, 149 institutions reported holding Alector Inc. (ALEC) in their 13F filings, up 13 from Q2 2025. 25 opened new positions and 12 sold out. The largest holders were FMR LLC ($44.9M), BlackRock, Inc. ($21.3M) and RTW Investments, LP ($20.7M). 7 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Alector Inc.
- CUSIP
- 014442107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 25 | $25.4M |
| Exits | 12 | $4.7M |
All 13F filers, Q2 2025 → Q3 2025: 13,669,605 shares bought and 9,431,921 shares sold, net +4,237,684 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 149 holders
| FMR LLC | 0.00% | Add +1.2% | 15,181,849 | $44.9M |
| BlackRock, Inc. | 0.00% | Reduce -9.7% | 7,197,973 | $21.3M |
| RTW Investments, LP | 0.26% | New | 6,990,806 | $20.7M |
| Vanguard Group Inc. | 0.00% | Add +0.8% | 6,034,659 | $17.9M |
| Merck & Co., Inc. | 4.60% | No change | 3,545,719 | $10.5M |
| Acadian Asset Management LLC | 0.01% | Add +9.3% | 2,372,985 | $7.0M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -55.2% | 2,185,032 | $6.5M |
| Geode Capital Management, LLC | 0.00% | Reduce -6.1% | 1,861,258 | $5.5M |
| State Street Corp. | 0.00% | Add +1.4% | 1,734,679 | $5.1M |
| Eversept Partners, LP | 0.34% | Reduce -25.0% | 1,488,725 | $4.4M |
| Euclidean Capital LLC | 1.63% | No change | 1,307,858 | $3.9M |
| Jacobs Levy Equity Management, Inc. | 0.01% | Reduce -7.0% | 1,230,974 | $3.6M |
| Millennium Management | 0.00% | Add +181.2% | 1,155,027 | $3.4M |
| Deutsche Bank AG | 0.00% | Add +7.9% | 1,068,215 | $3.2M |
| Deerfield Management Company, L.P. | 0.05% | No change | 1,055,192 | $3.1M |
| 683 Capital Management, LLC | 0.28% | New | 1,000,000 | $3.0M |
| 5AM Venture Management, LLC | 1.08% | No change | 995,841 | $2.9M |
| Vestal Point Capital, LP | 0.13% | Add +0.3% | 980,000 | $2.9M |
| D. E. Shaw & Co. | 0.00% | Add +83.1% | 978,204 | $2.9M |
| Renaissance Technologies | 0.00% | Reduce -24.4% | 949,150 | $2.8M |
| Barclays PLC | 0.00% | Add +414.4% | 873,375 | $2.6M |
| DAFNA Capital Management LLC | 0.59% | Reduce -12.6% | 798,351 | $2.4M |
| Ikarian Capital, LLC | 0.46% | Reduce -15.6% | 760,000 | $2.2M |
| Panagora Asset Management Inc. | 0.01% | Add +43.5% | 741,293 | $2.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +6.5% | 689,524 | $2.0M |
| Northern Trust Corp. | 0.00% | Reduce -3.7% | 633,709 | $1.9M |
| Royal Bank of Canada | 0.00% | Add +71.2% | 628,652 | $1.9M |
| Goldman Sachs Group Inc. | 0.00% | Add +62.9% | 609,909 | $1.8M |
| Boothbay Fund Management, LLC | 0.04% | Add +14.2% | 524,077 | $1.6M |
| Two Sigma Advisers, LP | 0.00% | Add +37.2% | 517,400 | $1.5M |
| Medici Capital LLC | 1.06% | Add +188.3% | 481,974 | $1.4M |
| Citadel Advisors | 0.00% | Reduce -14.5% | 471,581 | $1.4M |
| AQR Capital Management | 0.00% | Add +7.7% | 438,087 | $1.3M |
| Morgan Stanley | 0.00% | Reduce -28.4% | 434,168 | $1.3M |
| Jane Street Group, LLC | 0.00% | Add +1362.2% | 350,231 | $1.0M |
| New Leaf Venture Partners, L.L.C. | 2.33% | No change | 339,569 | $1.0M |
| Susquehanna International Group, LLP | 0.00% | Add +51.5% | 308,660 | $914K |
| Two Sigma Investments, LP | 0.00% | Add +38.3% | 307,179 | $909K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -22.8% | 295,846 | $876K |
| Mackenzie Financial Corp. | 0.00% | Add +3.4% | 283,712 | $840K |
| Ameriprise Financial Inc. | 0.00% | Add +1838.8% | 274,042 | $811K |
| TD Asset Management Inc | 0.00% | Reduce -58.0% | 273,738 | $810K |
| Bank of America Corp. | 0.00% | Reduce -28.4% | 246,283 | $729K |
| UBS Group AG | 0.00% | Add +450.2% | 230,499 | $682K |
| Bank of New York Mellon Corp | 0.00% | Reduce -16.5% | 224,484 | $664K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -30.9% | 216,574 | $641K |
| Invesco Ltd. | 0.00% | Add +9.4% | 192,311 | $569K |
| Alphabet Inc. | 0.02% | No change | 175,866 | $521K |
| Marshall Wace, LLP | 0.00% | New | 151,643 | $449K |
| JPMorgan Chase & Co. | 0.00% | Add +199.8% | 136,385 | $404K |
| Diadema Partners LP | 0.28% | Reduce -48.9% | 136,023 | $403K |
| Nuveen, LLC | 0.00% | Reduce -14.4% | 133,248 | $394K |
| Bridgeway Capital Management, LLC | 0.01% | No change | 115,000 | $340K |
| Rhumbline Advisers | 0.00% | Reduce -9.7% | 114,270 | $338K |
| STRS Ohio | 0.00% | No change | 110,400 | $327K |
| Russell Investments Group, Ltd. | 0.00% | Add +4.4% | 104,824 | $310K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 100,000 | $303K |
| Simplex Trading, LLC | 0.01% | New | 100,944 | $298K |
| Cubist Systematic Strategies, LLC | 0.00% | Add +358.6% | 100,067 | $296K |
| XTX Topco Ltd | 0.02% | Add +34.3% | 98,513 | $292K |
| Alliancebernstein L.P. | 0.00% | No change | 92,940 | $275K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -39.9% | 91,236 | $270K |
| Utah Retirement Systems | 0.00% | Add +40.0% | 72,002 | $213K |
| Jasper Ridge Partners, L.P. | 0.00% | Add +134.3% | 71,776 | $212K |
| Artia Global Partners LP | 0.04% | New | 71,029 | $210K |
| Public Employees Retirement System of Ohio | 0.00% | Add +763.3% | 68,200 | $202K |
| HRT Financial LP | 0.00% | New | 60,164 | $178K |
| Cannell & Spears LLC | 0.00% | Reduce -3.7% | 59,223 | $175K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +11.9% | 58,320 | $173K |
| Velan Capital Investment Management LP | 0.15% | No change | 55,000 | $163K |
| Citigroup Inc. | 0.00% | Add +9.1% | 53,938 | $160K |
| Ieq Capital, LLC | 0.00% | Reduce -10.1% | 53,050 | $157K |
| Wells Fargo & Company | 0.00% | Add +3.6% | 52,425 | $155K |
| Bank of Montreal | 0.00% | No change | 52,380 | $155K |
| HSBC Holdings PLC | 0.00% | Reduce -5.9% | 48,666 | $140K |
| Tudor Investment Corporation | 0.00% | Add +1.2% | 41,282 | $122K |
| Intech Investment Management LLC | 0.00% | Reduce -16.3% | 33,428 | $99K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -30.6% | 32,129 | $95K |
| Persistent Asset Partners Ltd | 0.07% | Reduce -48.9% | 31,240 | $92K |
| MetLife Investment Management, LLC | 0.00% | New | 28,820 | $85K |
| Prudential Financial Inc. | 0.00% | Add +31.4% | 28,022 | $83K |
| Cerity Partners LLC | 0.00% | Add +12.9% | 26,807 | $79K |
| Vontobel Holding Ltd. | 0.00% | Reduce -31.6% | 26,000 | $77K |
| Blackstone Inc. | 0.00% | No change | 25,715 | $76K |
| Cwm, LLC | 0.00% | Reduce -2.8% | 25,169 | $75K |
| Apollon Wealth Management, LLC | 0.00% | No change | 25,000 | $74K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +37.8% | 23,426 | $69K |
| Group One Trading LLC | 0.00% | New | 22,321 | $66K |
| Graham Capital Management, L.P. | 0.00% | Reduce -0.7% | 21,215 | $63K |
| American Century Companies Inc. | 0.00% | New | 20,481 | $61K |
| Erste Asset Management GmbH | 0.00% | No change | 19,000 | $58K |
| BNP Paribas Financial Markets | 0.00% | Add +57.0% | 18,269 | $54K |
| China Universal Asset Management Co., Ltd. | 0.00% | Reduce -11.7% | 17,741 | $53K |
| Sei Investments Co. | 0.00% | No change | 16,884 | $50K |
| Creative Planning | 0.00% | New | 15,721 | $47K |
| DLK Investment Management, LLC | 0.02% | No change | 15,500 | $46K |
| ProShare Advisors LLC | 0.00% | Reduce -23.1% | 15,431 | $46K |
| FNY Investment Advisers, LLC | 0.01% | Reduce -25.0% | 15,000 | $44K |
| Engineers Gate Manager LP | 0.00% | New | 14,493 | $43K |
| Hamilton Lane Advisors LLC | 0.02% | New | 14,402 | $43K |
"% of holder's portfolio" is ALEC's weight in each manager's 13F, not the share of Alector Inc. the manager owns.