AlectorALEC
13F holders, Q4 2025 (December 31)131holders −18
21new positions
39sold out
7famous investors
$1.57avg. 13F price*
At the end of Q4 2025, 131 institutions reported holding Alector Inc. (ALEC) in their 13F filings, down 18 from Q3 2025. 21 opened new positions and 39 sold out. The largest holders were TCG Crossover Management, LLC ($15.6M), BlackRock, Inc. ($11.2M) and Vanguard Group Inc. ($10.8M). 7 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Alector Inc.
- CUSIP
- 014442107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 21 | $32.9M |
| Exits | 39 | $26.9M |
All 13F filers, Q3 2025 → Q4 2025: 35,527,822 shares bought and 27,585,534 shares sold, net +7,942,288 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 131 holders
| TCG Crossover Management, LLC | 0.52% | New | 10,000,000 | $15.6M |
| BlackRock, Inc. | 0.00% | Reduce -0.7% | 7,147,766 | $11.2M |
| Vanguard Group Inc. | 0.00% | Add +14.5% | 6,908,054 | $10.8M |
| Foresite Capital Management IV, LLC | 2.64% | New | 3,887,200 | $6.1M |
| Merck & Co., Inc. | 2.00% | No change | 3,545,719 | $5.5M |
| Acadian Asset Management LLC | 0.01% | Add +45.1% | 3,442,449 | $5.4M |
| 683 Capital Management, LLC | 0.46% | Add +235.0% | 3,350,000 | $5.2M |
| Balyasny Asset Management L.P. | 0.01% | New | 3,265,575 | $5.1M |
| D. E. Shaw & Co. | 0.00% | Add +141.8% | 2,365,151 | $3.7M |
| FMR LLC | 0.00% | Reduce -85.3% | 2,231,171 | $3.5M |
| Jacobs Levy Equity Management, Inc. | 0.01% | Add +76.5% | 2,173,202 | $3.4M |
| Ikarian Capital, LLC | 0.42% | Add +174.0% | 2,082,606 | $3.2M |
| Geode Capital Management, LLC | 0.00% | Add +11.5% | 2,075,220 | $3.2M |
| Kynam Capital Management, LP | 0.20% | New | 2,000,000 | $3.1M |
| State Street Corp. | 0.00% | Add +4.6% | 1,814,298 | $2.8M |
| Renaissance Technologies | 0.00% | Add +62.6% | 1,543,650 | $2.4M |
| Medici Capital LLC | 2.57% | Add +211.3% | 1,500,520 | $2.3M |
| Millennium Management | 0.00% | Add +15.4% | 1,332,914 | $2.1M |
| Euclidean Capital LLC | 0.55% | No change | 1,307,858 | $2.0M |
| Marshall Wace, LLP | 0.00% | Add +669.5% | 1,166,817 | $1.8M |
| Spruce Street Capital LP | 0.58% | — | 1,117,986 | $1.7M |
| ADAR1 Capital Management, LLC | 0.13% | New | 1,108,000 | $1.7M |
| Deerfield Management Company, L.P. | 0.02% | No change | 1,055,192 | $1.6M |
| Two Sigma Investments, LP | 0.00% | Add +238.4% | 1,039,656 | $1.6M |
| Deutsche Bank AG | 0.00% | Reduce -3.1% | 1,035,154 | $1.6M |
| Eversept Partners, LP | 0.09% | Reduce -32.4% | 1,006,163 | $1.6M |
| Jane Street Group, LLC | 0.00% | Add +183.8% | 993,913 | $1.6M |
| DAFNA Capital Management LLC | 0.33% | Add +13.8% | 908,351 | $1.4M |
| Elmind Capital, LP | 0.41% | — | 900,000 | $1.4M |
| Panagora Asset Management Inc. | 0.00% | Add +14.7% | 850,298 | $1.3M |
| Vestal Point Capital, LP | 0.04% | Reduce -23.0% | 755,000 | $1.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.5% | 665,491 | $1.0M |
| Two Sigma Advisers, LP | 0.00% | Add +26.0% | 651,800 | $1.0M |
| Mackenzie Financial Corp. | 0.00% | Add +132.7% | 660,168 | $1.0M |
| AQR Capital Management | 0.00% | Add +36.9% | 599,569 | $935K |
| XTX Topco Ltd | 0.02% | Add +501.8% | 592,839 | $925K |
| Northern Trust Corp. | 0.00% | Reduce -7.3% | 587,653 | $917K |
| Boothbay Fund Management, LLC | 0.02% | Add +6.8% | 559,726 | $873K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -28.2% | 437,959 | $683K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 100,000 | $661K |
| Barclays PLC | 0.00% | Reduce -54.4% | 398,687 | $622K |
| Ameriprise Financial Inc. | 0.00% | Add +29.3% | 354,299 | $553K |
| Morgan Stanley | 0.00% | Reduce -26.5% | 319,072 | $498K |
| Susquehanna International Group, LLP | 0.00% | Reduce -5.7% | 291,180 | $454K |
| Invesco Ltd. | 0.00% | Add +45.3% | 279,468 | $436K |
| Gsa Capital Partners LLP | 0.03% | New | 225,566 | $352K |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.0% | 217,862 | $340K |
| Nano Cap New Millennium Growth Fund L P | 0.27% | — | 200,000 | $312K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -32.7% | 199,126 | $310K |
| Canada Pension Plan Investment Board | 0.00% | New | 172,300 | $269K |
| Public Employees Retirement System of Ohio | 0.00% | Add +99.4% | 136,000 | $212K |
| Bank of America Corp. | 0.00% | Reduce -45.4% | 134,506 | $210K |
| Utah Retirement Systems | 0.00% | Add +85.7% | 133,718 | $209K |
| Nuveen, LLC | 0.00% | No change | 133,248 | $208K |
| UBS Group AG | 0.00% | Reduce -48.2% | 119,411 | $186K |
| Bridgeway Capital Management, LLC | 0.00% | No change | 115,000 | $179K |
| STRS Ohio | 0.00% | No change | 110,400 | $172K |
| Graham Capital Management, L.P. | 0.01% | Add +394.2% | 104,851 | $164K |
| Rhumbline Advisers | 0.00% | Reduce -10.8% | 101,926 | $159K |
| Jasper Ridge Partners, L.P. | 0.00% | Add +32.5% | 95,068 | $148K |
| Citadel Advisors | 0.00% | Reduce -80.2% | 93,547 | $146K |
| Alliancebernstein L.P. | 0.00% | No change | 92,940 | $145K |
| Los Angeles Capital Management LLC | 0.00% | Add +2.0% | 93,052 | $141K |
| Wells Fargo & Company | 0.00% | Add +71.9% | 90,108 | $141K |
| Man Group plc | 0.00% | New | 86,162 | $134K |
| Simplex Trading, LLC | 0.00% | Reduce -18.8% | 82,017 | $128K |
| Squarepoint Ops LLC | 0.00% | New | 77,618 | $121K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -31.4% | 71,887 | $112K |
| Blackstone Inc. | 0.00% | Add +160.0% | 66,859 | $104K |
| Quadrature Capital Ltd | 0.00% | New | 62,273 | $97K |
| HRT Financial LP | 0.00% | Reduce -4.7% | 57,341 | $89K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -97.4% | 56,203 | $89K |
| Cannell & Spears LLC | 0.00% | Reduce -7.7% | 54,642 | $85K |
| Lexington Partners L.P. | 0.02% | Add +429.2% | 53,488 | $83K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -9.0% | 53,056 | $83K |
| HSBC Holdings PLC | 0.00% | Reduce -0.3% | 48,521 | $76K |
| Oxford Asset Management LLP | 0.02% | New | 42,905 | $67K |
| Tudor Investment Corporation | 0.00% | No change | 41,282 | $64K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +1472.0% | 39,520 | $62K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +16.0% | 37,271 | $58K |
| Intech Investment Management LLC | 0.00% | Add +3.2% | 34,510 | $54K |
| JPMorgan Chase & Co. | 0.00% | Reduce -76.1% | 32,623 | $51K |
| Prudential Financial Inc. | 0.00% | Add +15.0% | 32,225 | $50K |
| Vontobel Holding Ltd. | 0.00% | Add +15.4% | 30,000 | $47K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -86.7% | 28,829 | $45K |
| SG Americas Securities, LLC | 0.00% | New | 27,002 | $42K |
| Dynamic Technology Lab Private Ltd | 0.01% | New | 25,881 | $40K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 23,426 | $37K |
| Point72 Asset Management | 0.00% | Add +4162.4% | 23,102 | $36K |
| BNP Paribas Financial Markets | 0.00% | Add +22.5% | 22,385 | $35K |
| Virtu Financial LLC | 0.00% | New | 21,886 | $34K |
| Hershey Trust Co. | 0.00% | Add +100.0% | 20,572 | $32K |
| Bronte Capital Management Pty Ltd. | 0.00% | New | 19,282 | $30K |
| Sei Investments Co. | 0.00% | No change | 16,884 | $26K |
| ProShare Advisors LLC | 0.00% | Reduce -4.9% | 14,672 | $23K |
| Neuberger Berman Group LLC | 0.00% | New | 14,173 | $22K |
| Diversified Trust Co. | 0.00% | No change | 14,102 | $22K |
| Voya Investment Management LLC | 0.00% | No change | 13,929 | $22K |
| Cerity Partners LLC | 0.00% | Reduce -49.0% | 13,682 | $21K |
| R Squared Ltd | 0.01% | New | 12,474 | $19K |
| Cwm, LLC | 0.00% | Reduce -51.7% | 12,164 | $19K |
| New York State Common Retirement Fund | 0.00% | No change | 10,310 | $16K |
| Corient Private Wealth LP | 0.00% | New | 10,288 | $16K |
| HighTower Advisors, LLC | 0.00% | New | 10,011 | $16K |
| Texas Yale Capital Corp. | 0.00% | No change | 10,000 | $16K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 8,175 | $13K |
| Citigroup Inc. | 0.00% | Reduce -88.6% | 6,155 | $10K |
| Legal & General Group Plc | 0.00% | No change | 6,039 | $9K |
| California State Teachers Retirement System | 0.00% | Reduce -0.5% | 4,940 | $8K |
| Royal Bank of Canada | 0.00% | Reduce -99.3% | 4,678 | $7K |
| Sterling Capital Management LLC | 0.00% | Add +0.5% | 4,421 | $7K |
| Amalgamated Bank | 0.00% | Reduce -0.7% | 2,523 | $4K |
| GAMMA Investing LLC | 0.00% | New | 1,075 | $2K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -69.6% | 1,016 | $2K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 752 | $1K |
| Osaic Holdings, Inc. | 0.00% | Reduce -44.6% | 620 | $967 |
| True Wealth Design, LLC | 0.00% | Reduce -29.5% | 563 | $879 |
| Hughes Financial Services, LLC | 0.00% | No change | 553 | $863 |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -57.6% | 504 | $786 |
| Essential Partners LLC | 0.00% | Reduce -18.7% | 431 | $672 |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 415 | $647 |
| Wilmington Savings Fund Society, FSB | 0.00% | No change | 400 | $624 |
| Rockefeller Capital Management L.P. | 0.00% | Reduce -73.2% | 367 | $573 |
| Basecamp Wealth Advisors LLC | 0.00% | — | 329 | $513 |
| Mark Sheptoff Financial Planning, LLC | 0.00% | No change | 300 | $468 |
| Rothschild Investment LLC | 0.00% | Reduce -4.6% | 209 | $326 |
| National Bank of Canada | 0.00% | No change | 200 | $312 |
| Kingdom Financial Group LLC. | 0.00% | New | 48 | $75 |
| IFP Advisors, Inc | 0.00% | No change | 47 | $73 |
| SBI Securities Co., Ltd. | 0.00% | No change | 20 | $31 |
| Comerica Bank | 0.00% | Reduce -57.1% | 9 | $14 |
"% of holder's portfolio" is ALEC's weight in each manager's 13F, not the share of Alector Inc. the manager owns.