Alpine Immune SciencesALPN
13F holders, Q1 2024 (March 31)180holders
8famous investors
$39.64avg. 13F price*
At the end of Q1 2024, 180 institutions reported holding Alpine Immune Sciences Inc. (ALPN) in their 13F filings. The largest holders were Decheng Capital LLC ($329.7M), Avoro Capital Advisors LLC ($228.9M) and BlackRock Inc. ($141.7M). 8 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Alpine Immune Sciences Inc.
- CUSIP
- 02083G100
- Latest filing quarter
- Q1 2024
Total Exit/New Position Q1 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 63 | $492.1M |
| Exits | 15 | $120.0M |
Ownership 180 holders
| Decheng Capital LLC | 44.22% | Add +17.4% | 8,317,924 | $329.7M |
| Avoro Capital Advisors LLC | 2.67% | New | 5,775,000 | $228.9M |
| BlackRock Inc. | 0.00% | Add +16.9% | 3,575,092 | $141.7M |
| Frazier Life Sciences Management, L.P. | 5.25% | No change | 3,131,008 | $124.1M |
| T. Rowe Price Associates Inc. | 0.01% | Add +82.6% | 3,080,220 | $122.1M |
| State Street Corp. | 0.01% | Add +104.7% | 2,845,839 | $112.8M |
| Vanguard Group Inc. | 0.00% | Add +21.4% | 2,712,285 | $107.5M |
| Cormorant Asset Management, LP | 4.72% | Add +5.9% | 2,700,000 | $107.0M |
| Orbimed Advisors LLC | 1.95% | Add +5.7% | 2,680,496 | $106.3M |
| Lynx1 Capital Management LP | 23.00% | Reduce -40.9% | 2,253,183 | $89.3M |
| Paradigm Biocapital Advisors LP | 2.96% | Reduce -33.2% | 2,121,163 | $84.1M |
| Darwin Global Management, Ltd. | 10.46% | New | 1,982,016 | $78.6M |
| Commodore Capital LP | 3.64% | Reduce -14.6% | 1,375,000 | $54.5M |
| Octagon Capital Advisors LP | 5.98% | No change | 1,241,300 | $49.2M |
| Avidity Partners Management LP | 1.66% | New | 1,174,700 | $46.6M |
| Great Point Partners LLC | 6.97% | Reduce -69.5% | 1,128,499 | $44.7M |
| Franklin Resources Inc. | 0.01% | Reduce -10.4% | 1,093,203 | $43.3M |
| Geode Capital Management, LLC | 0.00% | Add +19.1% | 910,599 | $36.1M |
| Morgan Stanley | 0.00% | Add +9.9% | 789,645 | $31.3M |
| Two Sigma Advisers, LP | 0.06% | Add +153.3% | 668,775 | $26.5M |
| Vivo Capital, LLC | 1.63% | Reduce -36.5% | 520,505 | $20.8M |
| Two Sigma Investments, LP | 0.05% | Add +37.4% | 519,971 | $20.6M |
| Nuveen Asset Management, LLC | 0.01% | Add +294.9% | 513,175 | $20.3M |
| First Light Asset Management, LLC | 1.52% | New | 501,243 | $19.9M |
| Janus Henderson Group PLC | 0.01% | Reduce -22.7% | 450,827 | $17.8M |
| D. E. Shaw & Co. | 0.02% | Add +45.0% | 428,555 | $17.0M |
| Candriam S.C.A. | 0.11% | Reduce -11.7% | 415,000 | $16.5M |
| Eventide Asset Management, LLC | 0.25% | New | 408,542 | $16.2M |
| Artal Group S.A. | 0.41% | Add +699.4% | 405,784 | $16.1M |
| Balyasny Asset Management L.P. | 0.04% | New | 372,995 | $14.8M |
| Vestal Point Capital, LP | 1.15% | New | 350,000 | $13.9M |
| Northern Trust Corp. | 0.00% | Add +15.2% | 341,701 | $13.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +14.0% | 339,142 | $13.4M |
| Bank of New York Mellon Corp | 0.00% | Add +218.4% | 325,943 | $12.9M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | Reduce -56.6% | 310,000 | $12.3M |
| Invesco Ltd. | 0.00% | Add +12.8% | 272,627 | $10.8M |
| Voloridge Investment Management, LLC | 0.04% | Add +14.3% | 267,232 | $10.6M |
| Nan Fung Group Holdings Ltd | 9.69% | No change | 263,940 | $10.5M |
| Ikarian Capital, LLC | 2.82% | Reduce -46.4% | 261,365 | $10.4M |
| Atika Capital Management LLC | 1.14% | New | 256,000 | $10.1M |
| Woodline Partners LP | 0.09% | Reduce -74.6% | 254,334 | $10.1M |
| Renaissance Technologies | 0.02% | Add +13.1% | 244,981 | $9.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +21.5% | 240,435 | $9.5M |
| FMR LLC | 0.00% | Add +0.0% | 238,561 | $9.5M |
| Rafferty Asset Management, LLC | 0.03% | Add +192.7% | 234,625 | $9.3M |
| Integral Health Asset Management, LLC | 0.90% | New | 230,000 | $9.1M |
| Citigroup Inc. | 0.01% | Add +480.0% | 207,496 | $8.2M |
| Walleye Capital LLC | 0.10% | Reduce -43.7% | 206,104 | $8.2M |
| Deutsche Bank AG | 0.00% | Add +57.9% | 204,479 | $8.1M |
| Bank of America Corp. | 0.00% | Add +120.6% | 202,414 | $8.0M |
| Silverarc Capital Management, LLC | 2.21% | Reduce -33.2% | 199,020 | $7.9M |
| Jennison Associates LLC | 0.01% | Add +36.1% | 191,974 | $7.6M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -18.0% | 191,779 | $7.6M |
| Jane Street Group, LLC | 0.01% | Add +155.5% | 177,434 | $7.0M |
| ExodusPoint Capital Management, LP | 0.08% | Reduce -18.1% | 171,251 | $6.8M |
| Qube Research & Technologies Ltd | 0.01% | Reduce -20.6% | 163,323 | $6.5M |
| Wellington Management Group LLP | 0.00% | Add +46.6% | 161,145 | $6.4M |
| UBS Group AG | 0.00% | Add +133.2% | 153,473 | $6.1M |
| Citadel Advisors | 0.01% | Reduce -83.7% | 142,879 | $5.7M |
| Ensign Peak Advisors, Inc | 0.01% | Add +7.8% | 140,043 | $5.6M |
| Federated Hermes, Inc. | 0.01% | Add +37977.0% | 138,981 | $5.5M |
| Hillsdale Investment Management Inc. | 0.42% | New | 133,960 | $5.3M |
| Tri Locum Partners LP | 1.66% | New | 120,687 | $4.8M |
| TD Asset Management Inc | 0.00% | Add +256.7% | 118,418 | $4.7M |
| Exome Asset Management LLC | 3.97% | Reduce -32.6% | 117,000 | $4.6M |
| Trexquant Investment LP | 0.09% | Add +115.3% | 115,776 | $4.6M |
| Point72 Asset Management | 0.01% | New | 110,700 | $4.4M |
| Susquehanna International Group, LLP | 0.01% | Add +382.4% | 109,860 | $4.4M |
| Algert Global LLC | 0.17% | Add +284.7% | 108,841 | $4.3M |
| Handelsbanken Fonder AB | 0.02% | New | 102,000 | $4.0M |
| Rhenman & Partners Asset Management AB | 0.32% | New | 85,500 | $3.4M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +213.2% | 83,868 | $3.3M |
| Baker Bros. Advisors LP | 0.04% | New | 81,578 | $3.2M |
| Altium Capital Management LLC | 1.39% | Reduce -1.1% | 77,848 | $3.1M |
| BNP Paribas Financial Markets | 0.00% | Reduce -27.3% | 77,784 | $3.1M |
| Raymond James Financial Services Advisors, Inc. | 0.00% | New | 76,508 | $3.0M |
| Informed Momentum Co LLC | 0.46% | Reduce -54.0% | 74,899 | $3.0M |
| Boothbay Fund Management, LLC | 0.08% | Reduce -41.8% | 67,972 | $2.7M |
| Swiss National Bank | 0.00% | Add +11.0% | 63,500 | $2.5M |
| Rhumbline Advisers | 0.00% | Add +24.8% | 54,543 | $2.2M |
| Cinctive Capital Management LP | 0.11% | New | 54,071 | $2.1M |
| Monashee Investment Management LLC | 0.25% | Reduce -29.7% | 52,546 | $2.1M |
| Artia Global Partners LP | 0.50% | New | 51,714 | $2.0M |
| Moody Aldrich Partners LLC | 0.34% | New | 50,798 | $2.0M |
| Tudor Investment Corporation | 0.02% | New | 50,729 | $2.0M |
| Barclays PLC | 0.00% | Reduce -38.8% | 49,170 | $1.9M |
| Alps Advisors Inc. | 0.01% | Add +16.8% | 46,222 | $1.8M |
| Victory Capital Management Inc. | 0.00% | New | 45,064 | $1.8M |
| Sphera Funds Management LTD. | 0.29% | Reduce -80.9% | 44,841 | $1.8M |
| Alliancebernstein L.P. | 0.00% | Add +37.5% | 41,290 | $1.6M |
| AWM Investment Company, Inc. | 0.21% | No change | 40,000 | $1.6M |
| ClariVest Asset Management LLC | 0.16% | Add +0.2% | 38,873 | $1.5M |
| Capstone Investment Advisors, LLC | 0.05% | Add +51.1% | 38,212 | $1.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +215.8% | 37,925 | $1.5M |
| Profund Advisors LLC | 0.06% | Add +170.7% | 36,372 | $1.4M |
| Jefferies Financial Group Inc. | 0.03% | Reduce -65.0% | 35,000 | $1.4M |
| California State Teachers Retirement System | 0.00% | Add +5.3% | 32,823 | $1.3M |
| Credit Suisse AG/ | 0.00% | Add +20.4% | 32,211 | $1.3M |
| Legal & General Group Plc | 0.00% | Add +17.7% | 30,901 | $1.2M |
| State of Wisconsin Investment Board | 0.00% | Add +4.1% | 30,133 | $1.2M |
| JPMorgan Chase & Co. | 0.00% | Reduce -10.9% | 29,459 | $1.2M |
| Prelude Capital Management, LLC | 0.07% | Reduce -34.7% | 27,100 | $1.1M |
| Ziegler Capital Management, LLC | 0.04% | Add +7.1% | 23,982 | $951K |
| Capula Management Ltd | 0.03% | New | 23,970 | $950K |
| Driehaus Capital Management LLC | 0.01% | No change | 23,566 | $934K |
| Boston Partners | 0.00% | New | 23,101 | $916K |
| Wexford Capital LP | 0.19% | New | 23,100 | $916K |
| HighVista Strategies LLC | 0.32% | Reduce -42.8% | 22,783 | $903K |
| Atom Investors LP | 0.11% | New | 22,721 | $901K |
| Chartwell Investment Partners, LLC | 0.03% | New | 21,881 | $867K |
| Oppenheimer & Co. Inc. | 0.01% | New | 21,538 | $854K |
| Voya Investment Management LLC | 0.00% | Add +64.5% | 21,475 | $851K |
| Simplex Trading, LLC | 0.02% | New | 21,123 | $837K |
| Banque Cantonale Vaudoise | 0.03% | New | 20,129 | $798K |
| Sei Investments Co. | 0.00% | Reduce -13.6% | 20,058 | $795K |
| First Trust Advisors LP | 0.00% | New | 19,836 | $786K |
| MetLife Investment Management, LLC | 0.01% | Add +17.1% | 19,701 | $781K |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 18,982 | $752K |
| American International Group, Inc. | 0.00% | Add +17.1% | 18,949 | $751K |
| AQR Capital Management | 0.00% | Reduce -33.0% | 18,079 | $717K |
| New York State Common Retirement Fund | 0.00% | Add +18.7% | 17,657 | $700K |
| HighPoint Advisor Group LLC | 0.04% | Reduce -37.0% | 9,567 | $621K |
| OMERS ADMINISTRATION Corp | 0.01% | New | 15,400 | $610K |
| Bank of Montreal | 0.00% | New | 14,645 | $589K |
| Virtu Financial LLC | 0.04% | New | 14,813 | $587K |
| Scientech Research LLC | 0.31% | New | 14,742 | $584K |
| Millennium Management | 0.00% | Reduce -94.7% | 14,438 | $572K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +12.2% | 13,357 | $529K |
| China Universal Asset Management Co., Ltd. | 0.06% | Add +87.9% | 12,630 | $501K |
| Wells Fargo & Company | 0.00% | Add +35.6% | 12,526 | $497K |
| Hikari Power Ltd | 0.04% | No change | 12,445 | $493K |
| Western Wealth Management, LLC | 0.04% | Add +0.6% | 12,070 | $478K |
| ProShare Advisors LLC | 0.00% | New | 11,502 | $456K |
| E Fund Management Co., Ltd. | 0.03% | New | 11,087 | $439K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -28.5% | 14,430 | $397K |
| Entropy Technologies, LP | 0.04% | New | 9,688 | $384K |
| Superstring Capital Management LP | 0.24% | New | 9,038 | $358K |
| Arizona State Retirement System | 0.00% | New | 8,849 | $351K |
| Gotham Asset Management | 0.01% | New | 8,773 | $348K |
| GTS Securities LLC | 0.01% | New | 8,499 | $337K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -16.1% | 8,006 | $317K |
| Belvedere Trading LLC | 0.02% | New | 7,570 | $300K |
| Lazard Asset Management LLC | 0.00% | Add +39.0% | 7,518 | $298K |
| Teacher Retirement System of Texas | 0.00% | New | 7,165 | $284K |
| Allspring Global Investments Holdings, LLC | 0.00% | Add +331.1% | 6,414 | $254K |
| Commonwealth Equity Services, LLC | 0.00% | New | 6,210 | $246K |
| Farallon Capital Management, L.L.C. | 0.00% | New | 5,900 | $234K |
| Harvest Investment Services, LLC | 0.09% | New | 5,887 | $233K |
| Glenmede Trust Co. NA | 0.00% | New | 5,780 | $229K |
| Landscape Capital Management, L.L.C. | 0.02% | New | 5,459 | $216K |
| Virtus Advisers, LLC | 0.10% | Reduce -6.4% | 4,591 | $182K |
| Ameritas Investment Partners, Inc. | 0.01% | Add +13.8% | 3,835 | $152K |
| US Bancorp \de | 0.00% | New | 3,240 | $128K |
| SG Americas Securities, LLC | 0.00% | New | 2,686 | $106K |
| Metropolitan Life Insurance Co | 0.00% | Add +16.3% | 2,027 | $80K |
| STRS Ohio | 0.00% | New | 1,900 | $75K |
| Royal Bank of Canada | 0.00% | Reduce -84.1% | 1,611 | $64K |
| EntryPoint Capital, LLC | 0.05% | Add +1239.3% | 1,433 | $57K |
| Amalgamated Bank | 0.00% | Reduce -64.9% | 1,298 | $51K |
| Aquatic Capital Management LLC | 0.00% | Reduce -14.3% | 1,200 | $48K |
| KBC Group NV | 0.00% | New | 1,107 | $44K |
| Pacer Advisors, Inc. | 0.00% | New | 1,095 | $43K |
| EcoR1 Capital, LLC | 0.00% | New | 1,000 | $40K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -87.0% | 711 | $28K |
| Group One Trading LLC | 0.00% | Add +155.1% | 699 | $28K |
| Russell Investments Group, Ltd. | 0.00% | New | 691 | $27K |
| Osaic Holdings, Inc. | 0.00% | Add +5.3% | 651 | $26K |
| Tucker Asset Management LLC | 0.00% | New | 500 | $20K |
| NewEdge Advisors, LLC | 0.00% | No change | 469 | $19K |
| Daiwa Securities Group Inc. | 0.00% | No change | 238 | $9K |
| Bfsg, LLC | 0.00% | Reduce -50.0% | 175 | $7K |
| PNC Financial Services Group, Inc. | 0.00% | New | 54 | $2K |
| Nisa Investment Advisors, LLC | 0.00% | Add +275.0% | 45 | $2K |
| GAMMA Investing LLC | 0.00% | Add +59.3% | 43 | $2K |
| Farther Finance Advisors, LLC | 0.00% | No change | 20 | $804 |
| Riggs Asset Managment Co. Inc. | 0.00% | New | 16 | $635 |
| Principal Securities, Inc. | 0.00% | New | 6 | $238 |
| Avior Wealth Management, LLC | 0.00% | New | 6 | $237 |
| Rothschild Investment LLC | 0.00% | New | 5 | $198 |
| Covestor Ltd | 0.00% | New | 4 | $0 |
"% of holder's portfolio" is ALPN's weight in each manager's 13F, not the share of Alpine Immune Sciences Inc. the manager owns.