AnaptysbioANAB
13F holders, Q1 2026 (March 31)At the end of Q1 2026, 208 institutions reported holding Anaptysbio Inc. (ANAB) in their 13F filings, up 29 from Q4 2025. 45 opened new positions and 18 sold out. The largest holders were EcoR1 Capital, LLC ($437.0M), BlackRock, Inc. ($93.2M) and Tang Capital Management LLC ($73.8M). 9 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Anaptysbio Inc.
- CUSIP
- 032724106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 45 | $67.5M |
| Exits | 18 | $9.0M |
All 13F filers, Q4 2025 → Q1 2026: 3,494,031 shares bought and 4,221,253 shares sold, net −727,222 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 208 holders
| EcoR1 Capital, LLC | 18.68% | No change | 7,880,094 | $437.0M |
| BlackRock, Inc. | 0.00% | Reduce -3.1% | 1,681,380 | $93.2M |
| Tang Capital Management LLC | 3.75% | Reduce -0.1% | 1,330,879 | $73.8M |
| Morgan Stanley | 0.00% | Reduce -3.9% | 993,905 | $55.1M |
| State Street Corp. | 0.00% | Reduce -5.8% | 992,445 | $55.0M |
| Affinity Asset Advisors, LLC | 3.12% | Add +111.4% | 940,000 | $52.1M |
| Vanguard Capital Management LLC | 0.00% | — | 853,151 | $47.3M |
| Palo Alto Investors LP | 5.41% | Reduce -7.5% | 638,161 | $35.4M |
| 683 Capital Management, LLC | 3.39% | Reduce -3.6% | 625,000 | $34.7M |
| D. E. Shaw & Co. | 0.03% | Reduce -13.6% | 579,296 | $32.1M |
| First Light Asset Management, LLC | 2.81% | Reduce -12.5% | 565,431 | $31.4M |
| Sanofi | 9.04% | No change | 821,917 | $30.4M |
| Geode Capital Management, LLC | 0.00% | Add +10.8% | 520,241 | $28.9M |
| Vanguard Portfolio Management LLC | 0.00% | — | 519,870 | $28.8M |
| Bank of America Corp. | 0.00% | Add +283.2% | 501,086 | $27.8M |
| Arrowstreet Capital, Limited Partnership | 0.01% | Reduce -12.1% | 492,120 | $27.3M |
| Millennium Management | 0.02% | Reduce -41.5% | 475,572 | $26.4M |
| FMR LLC | 0.00% | Add +1643.8% | 472,704 | $26.2M |
| Two Sigma Investments, LP | 0.02% | Add +81.2% | 465,083 | $25.8M |
| Federated Hermes, Inc. | 0.03% | Add +21.6% | 364,121 | $20.2M |
| Woodline Partners LP | 0.07% | Reduce -31.3% | 344,256 | $19.1M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -16.6% | 332,743 | $18.5M |
| Synergy Asset Management, LLC | 1.87% | New | 317,106 | $17.6M |
| Nuveen, LLC | 0.00% | Reduce -0.2% | 316,065 | $17.5M |
| Squarepoint Ops LLC | 0.03% | Add +66.5% | 267,703 | $14.8M |
| Qube Research & Technologies Ltd | 0.02% | Add +133.8% | 254,736 | $14.1M |
| Sofinnova Investments, Inc. | 0.69% | Reduce -13.7% | 248,253 | $13.8M |
| Apis Capital Advisors, LLC | 2.04% | New | 238,000 | $13.2M |
| Citadel Advisors | 0.01% | Add +113.2% | 233,450 | $12.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.0% | 192,687 | $10.7M |
| Northern Trust Corp. | 0.00% | Add +0.9% | 183,519 | $10.2M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.02% | Add +29.5% | 158,562 | $8.8M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 135,082 | $7.5M |
| HSBC Holdings PLC | 0.00% | New | 125,717 | $7.1M |
| Ensign Peak Advisors, Inc | 0.01% | Reduce -41.7% | 125,633 | $7.0M |
| Invesco Ltd. | 0.00% | Reduce -2.3% | 121,103 | $6.7M |
| Victory Capital Management Inc. | 0.00% | Reduce -2.1% | 108,203 | $6.0M |
| BNP Paribas Financial Markets | 0.00% | Reduce -41.2% | 96,971 | $5.4M |
| HighMark Wealth Management LLC | 2.12% | No change | 94,050 | $5.2M |
| Nomura Asset Management International Inc. | 0.01% | No change | 93,732 | $5.2M |
| Renaissance Technologies | 0.01% | Add +19.1% | 90,900 | $5.0M |
| Jane Street Group, LLC | 0.01% | Add +1.9% | 86,038 | $4.8M |
| Trexquant Investment LP | 0.03% | Add +44.8% | 85,167 | $4.7M |
| UBS Group AG | 0.00% | Add +13.8% | 79,670 | $4.4M |
| Voloridge Investment Management, LLC | 0.02% | Reduce -65.5% | 78,952 | $4.4M |
| Citigroup Inc. | 0.00% | Reduce -0.1% | 73,406 | $4.1M |
| Marshall Wace, LLP | 0.00% | New | 68,047 | $3.8M |
| Granahan Investment Management, LLC | 0.18% | Reduce -47.4% | 66,182 | $3.7M |
| Franklin Resources Inc. | 0.00% | New | 65,820 | $3.7M |
| Prudential Financial Inc. | 0.00% | New | 64,050 | $3.6M |
| Fisher Asset Management | 0.00% | Add +0.1% | 56,596 | $3.1M |
| Point72 Asset Management | 0.01% | Reduce -97.1% | 55,303 | $3.1M |
| Deutsche Bank AG | 0.00% | Add +261.9% | 52,038 | $2.9M |
| Bank of New York Mellon Corp | 0.00% | Reduce -7.6% | 51,115 | $2.8M |
| XTX Topco Ltd | 0.05% | Add +30.8% | 50,537 | $2.8M |
| Wellington Management Group LLP | 0.00% | Reduce -23.4% | 46,881 | $2.6M |
| Penserra Capital Management LLC | 0.03% | Reduce -22.9% | 43,430 | $2.4M |
| Bleakley Financial Group, LLC | 0.04% | Reduce -1.0% | 43,120 | $2.4M |
| HRT Financial LP | 0.01% | Reduce -42.2% | 40,504 | $2.2M |
| Moody Aldrich Partners LLC | 0.39% | Reduce -17.1% | 39,455 | $2.2M |
| Tidal Investments LLC | 0.01% | New | 36,352 | $2.0M |
| Susquehanna Portfolio Strategies, LLC | 0.03% | No change | 35,948 | $2.0M |
| Mackenzie Financial Corp. | 0.00% | Add +39.2% | 33,720 | $1.9M |
| Virtu Financial LLC | 0.08% | New | 33,323 | $1.8M |
| Wells Fargo & Company | 0.00% | Add +49.4% | 33,180 | $1.8M |
| AQR Capital Management | 0.00% | Add +23.4% | 32,467 | $1.8M |
| Tema ETFs LLC | 0.12% | Add +37.7% | 31,069 | $1.7M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.7% | 30,727 | $1.7M |
| T. Rowe Price Associates Inc. | 0.00% | Add +14.2% | 29,691 | $1.6M |
| Jacobs Levy Equity Management, Inc. | 0.01% | Reduce -48.0% | 28,625 | $1.6M |
| Martingale Asset Management L P | 0.04% | New | 28,142 | $1.6M |
| Engineers Gate Manager LP | 0.02% | Add +155.7% | 27,815 | $1.5M |
| State of Wisconsin Investment Board | 0.00% | Add +208.4% | 27,619 | $1.5M |
| Swiss National Bank | 0.00% | No change | 27,600 | $1.5M |
| Alliancebernstein L.P. | 0.00% | Add +2.6% | 31,320 | $1.5M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -22.8% | 27,249 | $1.5M |
| Eversept Partners, LP | 0.10% | Reduce -77.6% | 27,089 | $1.5M |
| Susquehanna International Group, LLP | 0.00% | New | 26,577 | $1.5M |
| SG Americas Securities, LLC | 0.00% | Add +138.3% | 24,851 | $1.4M |
| Headlands Technologies LLC | 0.16% | Reduce -2.9% | 24,558 | $1.4M |
| Rhumbline Advisers | 0.00% | Reduce -4.7% | 23,848 | $1.3M |
| Y-Intercept (Hong Kong) Ltd | 0.02% | Reduce -31.4% | 22,701 | $1.3M |
| J. Goldman & Co LP | 0.05% | New | 21,205 | $1.2M |
| Hussman Strategic Advisors, Inc. | 0.25% | New | 21,000 | $1.2M |
| Credit Agricole S A | 0.00% | Reduce -50.0% | 20,000 | $1.1M |
| DCF Advisers, LLC | 0.39% | Reduce -46.7% | 18,775 | $1.0M |
| Walleye Capital LLC | 0.01% | New | 18,425 | $1.0M |
| PDT Partners, LLC | 0.06% | Reduce -59.1% | 17,595 | $976K |
| Creative Planning | 0.00% | Add +10.4% | 16,836 | $934K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Add +174.4% | 16,050 | $890K |
| Los Angeles Capital Management LLC | 0.00% | Add +3.7% | 15,664 | $869K |
| Canada Pension Plan Investment Board | 0.00% | New | 14,900 | $826K |
| Twinbeech Capital LP | 0.08% | New | 14,518 | $805K |
| Voya Investment Management LLC | 0.00% | Add +12.4% | 14,346 | $796K |
| California State Teachers Retirement System | 0.00% | Reduce -1.0% | 14,000 | $776K |
| Gotham Asset Management | 0.00% | New | 13,972 | $775K |
| Cresset Asset Management, LLC | 0.00% | Reduce -8.3% | 13,868 | $769K |
| Legal & General Group Plc | 0.00% | Reduce -23.9% | 13,831 | $767K |
| Brookwood Investment Group LLC | 0.09% | New | 13,362 | $741K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -32.6% | 13,288 | $737K |
"% of holder's portfolio" is ANAB's weight in each manager's 13F, not the share of Anaptysbio Inc. the manager owns.