AnaptysbioANAB
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 147 institutions reported holding Anaptysbio Inc. (ANAB) in their 13F filings, down 6 from Q1 2025. 25 opened new positions and 31 sold out. The largest holders were EcoR1 Capital, LLC ($174.9M), First Light Asset Management, LLC ($78.6M) and Point72 Asset Management ($54.9M). 8 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Anaptysbio Inc.
- CUSIP
- 032724106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 25 | $17.5M |
| Exits | 31 | $43.9M |
All 13F filers, Q1 2025 → Q2 2025: 5,270,834 shares bought and 8,460,599 shares sold, net −3,189,765 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 147 holders
| EcoR1 Capital, LLC | 10.38% | No change | 7,880,094 | $174.9M |
| First Light Asset Management, LLC | 10.19% | Reduce -23.6% | 3,539,593 | $78.6M |
| Point72 Asset Management | 0.14% | Add +4.5% | 2,474,874 | $54.9M |
| Morgan Stanley | 0.00% | Add +270.5% | 1,869,840 | $41.5M |
| BlackRock, Inc. | 0.00% | Reduce -17.9% | 1,786,934 | $39.7M |
| Vanguard Group Inc. | 0.00% | Add +1.3% | 1,537,550 | $34.1M |
| Tang Capital Management LLC | 1.49% | Reduce -13.9% | 1,330,879 | $29.5M |
| UBS Group AG | 0.01% | Add +159.6% | 1,272,499 | $28.2M |
| Bank of America Corp. | 0.00% | Reduce -5.9% | 1,076,799 | $23.9M |
| Citigroup Inc. | 0.02% | Reduce -2.3% | 1,046,488 | $23.2M |
| Sofinnova Investments, Inc. | 1.56% | Reduce -11.0% | 1,032,362 | $22.9M |
| Sanofi | 10.38% | No change | 821,917 | $18.2M |
| State Street Corp. | 0.00% | Reduce -4.6% | 821,031 | $18.2M |
| Palo Alto Investors LP | 3.84% | Reduce -20.4% | 812,821 | $18.0M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -26.4% | 673,171 | $14.9M |
| Victory Capital Management Inc. | 0.01% | Add +30.9% | 532,085 | $11.8M |
| Woodline Partners LP | 0.06% | Reduce -36.7% | 501,023 | $11.1M |
| 683 Capital Management, LLC | 1.19% | Add +155.6% | 500,000 | $11.1M |
| Geode Capital Management, LLC | 0.00% | Reduce -5.7% | 463,358 | $10.3M |
| Jacobs Levy Equity Management, Inc. | 0.03% | Add +2134.8% | 368,447 | $8.2M |
| Franklin Resources Inc. | 0.00% | Add +0.0% | 354,508 | $7.9M |
| Nuveen, LLC | 0.00% | Add +477.6% | 323,534 | $7.2M |
| Soleus Capital Management, L.P. | 0.49% | Add +214.6% | 321,040 | $7.1M |
| Two Sigma Advisers, LP | 0.01% | Add +8.3% | 290,400 | $6.4M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -0.3% | 279,835 | $6.2M |
| Renaissance Technologies | 0.01% | Reduce -22.3% | 263,086 | $5.8M |
| JPMorgan Chase & Co. | 0.00% | Add +1631.6% | 247,625 | $5.5M |
| Two Sigma Investments, LP | 0.01% | Reduce -13.0% | 231,369 | $5.1M |
| Ensign Peak Advisors, Inc | 0.01% | No change | 215,454 | $4.8M |
| Millennium Management | 0.00% | Add +1043.0% | 203,542 | $4.5M |
| Trexquant Investment LP | 0.05% | Add +29.8% | 199,242 | $4.4M |
| Northern Trust Corp. | 0.00% | Reduce -7.8% | 196,263 | $4.4M |
| Susquehanna International Group, LLP | 0.01% | Add +327.0% | 189,327 | $4.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +2.5% | 157,135 | $3.5M |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 150,810 | $3.3M |
| HighMark Wealth Management LLC | 1.58% | Add +58.2% | 145,550 | $3.2M |
| Granahan Investment Management, LLC | 0.12% | Reduce -10.1% | 131,655 | $2.9M |
| Camber Capital Management LP | 0.39% | Reduce -83.3% | 125,000 | $2.8M |
| Citadel Advisors | 0.00% | Reduce -68.3% | 118,286 | $2.6M |
| D. E. Shaw & Co. | 0.00% | Reduce -13.3% | 112,349 | $2.5M |
| Squarepoint Ops LLC | 0.01% | New | 109,388 | $2.4M |
| Barclays PLC | 0.00% | Add +77.9% | 99,999 | $2.2M |
| Macquarie Group Ltd. | 0.00% | No change | 93,732 | $2.1M |
| Balyasny Asset Management L.P. | 0.00% | Add +189.5% | 92,852 | $2.1M |
| Sectoral Asset Management Inc. | 1.23% | New | 83,900 | $1.9M |
| Invesco Ltd. | 0.00% | Add +289.8% | 83,174 | $1.8M |
| Wellington Management Group LLP | 0.00% | Add +5.5% | 80,213 | $1.8M |
| Voya Investment Management LLC | 0.00% | Reduce -24.7% | 73,005 | $1.6M |
| FMR LLC | 0.00% | Reduce -96.2% | 72,119 | $1.6M |
| Gsa Capital Partners LLP | 0.11% | New | 69,799 | $1.6M |
| Aquatic Capital Management LLC | 0.03% | New | 65,810 | $1.5M |
| Moody Aldrich Partners LLC | 0.26% | Reduce -27.8% | 60,094 | $1.3M |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.2% | 59,225 | $1.3M |
| Fisher Asset Management | 0.00% | Add +0.0% | 58,899 | $1.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +42.6% | 49,805 | $1.1M |
| DCF Advisers, LLC | 0.51% | Add +37.7% | 48,000 | $1.1M |
| Jane Street Group, LLC | 0.00% | New | 44,668 | $992K |
| PDT Partners, LLC | 0.06% | Reduce -0.1% | 44,465 | $987K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.02% | Reduce -18.1% | 38,528 | $855K |
| Bleakley Financial Group, LLC | 0.02% | New | 37,551 | $834K |
| FMB Wealth Management | 0.38% | No change | 35,592 | $790K |
| Skandinaviska Enskilda Banken AB (publ) | 0.00% | No change | 33,523 | $744K |
| SummitTX Capital, L.P. | 0.03% | Reduce -41.5% | 33,434 | $742K |
| Panagora Asset Management Inc. | 0.00% | New | 33,369 | $741K |
| Wells Fargo & Company | 0.00% | Add +192.9% | 33,328 | $740K |
| Susquehanna Portfolio Strategies, LLC | 0.02% | New | 32,803 | $728K |
| Rhumbline Advisers | 0.00% | Reduce -0.6% | 30,705 | $682K |
| XTX Topco Ltd | 0.03% | New | 30,642 | $680K |
| Alliancebernstein L.P. | 0.00% | No change | 30,520 | $678K |
| AQR Capital Management | 0.00% | Reduce -7.6% | 27,722 | $615K |
| Rafferty Asset Management, LLC | 0.00% | Reduce -13.9% | 26,829 | $596K |
| Swiss National Bank | 0.00% | Reduce -18.5% | 26,400 | $586K |
| Engineers Gate Manager LP | 0.01% | New | 24,745 | $549K |
| Russell Investments Group, Ltd. | 0.00% | New | 23,791 | $528K |
| ExodusPoint Capital Management, LP | 0.01% | Add +8.3% | 23,756 | $527K |
| Brevan Howard Capital Management LP | 0.01% | Add +61.7% | 22,953 | $510K |
| Legal & General Group Plc | 0.00% | Reduce -4.2% | 19,504 | $433K |
| Assenagon Asset Management S.A. | 0.00% | Reduce -93.0% | 16,959 | $376K |
| Creative Planning | 0.00% | Add +26.9% | 16,854 | $374K |
| Alps Advisors Inc. | 0.00% | Reduce -31.4% | 15,863 | $352K |
| Ikarian Capital, LLC | 0.12% | New | 15,662 | $348K |
| Nebula Research & Development LLC | 0.03% | Add +0.2% | 15,533 | $345K |
| Allianz Asset Management GmbH | 0.00% | New | 15,200 | $337K |
| Los Angeles Capital Management LLC | 0.00% | New | 15,027 | $334K |
| Exome Asset Management LLC | 0.27% | Reduce -87.1% | 15,000 | $333K |
| California State Teachers Retirement System | 0.00% | Reduce -2.6% | 14,217 | $316K |
| Cresset Asset Management, LLC | 0.00% | Reduce -10.8% | 13,033 | $289K |
| Deutsche Bank AG | 0.00% | Reduce -19.7% | 12,681 | $282K |
| Corton Capital Inc. | 0.31% | Add +12.2% | 12,004 | $266K |
| Tema ETFs LLC | 0.07% | New | 11,404 | $253K |
| NEOS Investment Management LLC | 0.00% | New | 11,404 | $253K |
| Intech Investment Management LLC | 0.00% | New | 10,795 | $240K |
| Tudor Investment Corporation | 0.00% | Reduce -7.6% | 9,419 | $209K |
| Federated Hermes, Inc. | 0.00% | No change | 8,274 | $184K |
| New York State Common Retirement Fund | 0.00% | No change | 7,924 | $176K |
| Glenmede Investment Management, LP | 0.00% | — | 7,546 | $168K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +215.1% | 6,498 | $144K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -4.1% | 5,901 | $131K |
| US Bancorp \de | 0.00% | Add +236.4% | 5,898 | $131K |
| SG Americas Securities, LLC | 0.00% | Reduce -59.4% | 4,921 | $109K |
"% of holder's portfolio" is ANAB's weight in each manager's 13F, not the share of Anaptysbio Inc. the manager owns.