AnaptysbioANAB
13F holders, Q3 2025 (September 30)166holders +19
34new positions
14sold out
8famous investors
$30.95avg. 13F price*
At the end of Q3 2025, 166 institutions reported holding Anaptysbio Inc. (ANAB) in their 13F filings, up 19 from Q2 2025. 34 opened new positions and 14 sold out. The largest holders were EcoR1 Capital, LLC ($241.3M), Point72 Asset Management ($69.4M) and BlackRock, Inc. ($52.7M). 8 famous investors held it, including Steve Cohen (0.2% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Anaptysbio Inc.
- CUSIP
- 032724106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 34 | $15.1M |
| Exits | 14 | $5.8M |
All 13F filers, Q2 2025 → Q3 2025: 4,518,050 shares bought and 9,471,191 shares sold, net −4,953,141 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 166 holders
| EcoR1 Capital, LLC | 11.60% | No change | 7,880,094 | $241.3M |
| Point72 Asset Management | 0.16% | Reduce -8.5% | 2,265,528 | $69.4M |
| BlackRock, Inc. | 0.00% | Reduce -3.6% | 1,722,324 | $52.7M |
| Morgan Stanley | 0.00% | Reduce -16.8% | 1,556,258 | $47.7M |
| Millennium Management | 0.04% | Add +646.4% | 1,519,230 | $46.5M |
| Vanguard Group Inc. | 0.00% | Reduce -3.9% | 1,476,989 | $45.2M |
| Tang Capital Management LLC | 1.57% | Add +0.2% | 1,333,639 | $40.8M |
| First Light Asset Management, LLC | 2.86% | Reduce -72.0% | 990,161 | $30.3M |
| State Street Corp. | 0.00% | Add +6.4% | 873,432 | $26.7M |
| Assenagon Asset Management S.A. | 0.04% | Add +4852.7% | 839,934 | $25.7M |
| Sanofi | 9.67% | No change | 821,917 | $25.2M |
| Palo Alto Investors LP | 3.82% | Reduce -17.1% | 673,520 | $20.6M |
| Soleus Capital Management, L.P. | 1.02% | Add +95.0% | 626,040 | $19.2M |
| 683 Capital Management, LLC | 1.59% | Add +9.4% | 547,000 | $16.7M |
| Woodline Partners LP | 0.07% | No change | 501,023 | $15.3M |
| Geode Capital Management, LLC | 0.00% | Add +2.2% | 473,626 | $14.5M |
| Franklin Resources Inc. | 0.00% | Reduce -86.7% | 47,332 | $11.6M |
| Jacobs Levy Equity Management, Inc. | 0.05% | Add +2.7% | 378,452 | $11.6M |
| Two Sigma Advisers, LP | 0.02% | Add +28.7% | 373,700 | $11.4M |
| Arrowstreet Capital, Limited Partnership | 0.01% | Add +145.7% | 370,458 | $11.3M |
| D. E. Shaw & Co. | 0.01% | Add +211.0% | 349,360 | $10.7M |
| Nuveen, LLC | 0.00% | Add +4.9% | 339,271 | $10.4M |
| Goldman Sachs Group Inc. | 0.00% | Add +17.9% | 329,820 | $10.1M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -55.5% | 299,311 | $9.2M |
| Two Sigma Investments, LP | 0.01% | Add +10.8% | 256,420 | $7.9M |
| Sofinnova Investments, Inc. | 0.48% | Reduce -75.4% | 254,268 | $7.8M |
| Ensign Peak Advisors, Inc | 0.01% | No change | 215,454 | $6.6M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +31.4% | 206,441 | $6.3M |
| Victory Capital Management Inc. | 0.00% | Reduce -61.6% | 204,055 | $6.2M |
| Northern Trust Corp. | 0.00% | Reduce -0.4% | 195,563 | $6.0M |
| Sectoral Asset Management Inc. | 3.68% | Add +131.8% | 194,485 | $6.0M |
| Federated Hermes, Inc. | 0.01% | Add +2236.6% | 193,327 | $5.9M |
| Jane Street Group, LLC | 0.01% | Add +305.5% | 181,112 | $5.5M |
| Granahan Investment Management, LLC | 0.19% | Add +12.2% | 147,773 | $4.5M |
| Skandinaviska Enskilda Banken AB (publ) | 0.02% | Add +333.1% | 145,191 | $4.4M |
| Susquehanna International Group, LLP | 0.01% | Reduce -23.6% | 144,604 | $4.4M |
| HighMark Wealth Management LLC | 1.95% | Reduce -7.2% | 135,050 | $4.4M |
| Bank of America Corp. | 0.00% | Reduce -88.2% | 127,241 | $3.9M |
| Renaissance Technologies | 0.01% | Reduce -53.1% | 123,300 | $3.8M |
| Trexquant Investment LP | 0.04% | Reduce -43.9% | 111,778 | $3.4M |
| BNP Paribas Financial Markets | 0.00% | Add +2756.5% | 105,663 | $3.2M |
| Macquarie Group Ltd. | 0.00% | No change | 93,732 | $2.9M |
| Algert Global LLC | 0.04% | New | 83,767 | $2.6M |
| Jump Financial, LLC | 0.03% | New | 82,077 | $2.5M |
| UBS Group AG | 0.00% | Reduce -94.1% | 75,262 | $2.3M |
| Citigroup Inc. | 0.00% | Reduce -93.3% | 70,534 | $2.2M |
| Squarepoint Ops LLC | 0.00% | Reduce -37.8% | 68,014 | $2.1M |
| Wellington Management Group LLP | 0.00% | Reduce -16.8% | 66,731 | $2.0M |
| Panagora Asset Management Inc. | 0.01% | Add +91.4% | 63,857 | $2.0M |
| Barclays PLC | 0.00% | Reduce -36.5% | 63,452 | $1.9M |
| Fisher Asset Management | 0.00% | Reduce -0.0% | 58,878 | $1.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.7% | 57,030 | $1.7M |
| Walleye Capital LLC | 0.02% | New | 56,422 | $1.7M |
| Marshall Wace, LLP | 0.00% | New | 54,416 | $1.7M |
| FMR LLC | 0.00% | Reduce -26.3% | 53,162 | $1.6M |
| Moody Aldrich Partners LLC | 0.29% | Reduce -17.0% | 49,882 | $1.5M |
| Ikarian Capital, LLC | 0.30% | Add +209.1% | 48,410 | $1.5M |
| DCF Advisers, LLC | 0.56% | No change | 48,000 | $1.5M |
| PDT Partners, LLC | 0.08% | Reduce -3.3% | 43,001 | $1.3M |
| Invesco Ltd. | 0.00% | Reduce -49.0% | 42,381 | $1.3M |
| Bleakley Financial Group, LLC | 0.03% | Add +6.5% | 39,981 | $1.2M |
| Gsa Capital Partners LLP | 0.10% | Reduce -46.6% | 37,274 | $1.1M |
| Susquehanna Portfolio Strategies, LLC | 0.02% | Add +8.1% | 35,448 | $1.1M |
| Russell Investments Group, Ltd. | 0.00% | Add +43.0% | 34,032 | $1.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -33.2% | 33,271 | $1.0M |
| Aquatic Capital Management LLC | 0.02% | Reduce -52.4% | 31,298 | $958K |
| Alliancebernstein L.P. | 0.00% | No change | 30,520 | $935K |
| Rafferty Asset Management, LLC | 0.00% | Add +12.1% | 30,085 | $921K |
| Rhumbline Advisers | 0.00% | Reduce -4.8% | 29,244 | $895K |
| Engineers Gate Manager LP | 0.01% | Add +17.8% | 29,137 | $892K |
| Swiss National Bank | 0.00% | Add +7.6% | 28,400 | $870K |
| Boothbay Fund Management, LLC | 0.02% | New | 27,402 | $839K |
| ExodusPoint Capital Management, LP | 0.01% | Add +11.6% | 26,500 | $811K |
| Citadel Advisors | 0.00% | Reduce -77.6% | 26,480 | $811K |
| AQR Capital Management | 0.00% | Reduce -5.6% | 26,174 | $801K |
| Brevan Howard Capital Management LP | 0.01% | Add +10.2% | 25,299 | $775K |
| HRT Financial LP | 0.00% | New | 25,025 | $766K |
| Legal & General Group Plc | 0.00% | No change | 19,504 | $597K |
| Campbell & CO Investment Adviser LLC | 0.04% | New | 18,281 | $560K |
| XTX Topco Ltd | 0.03% | Reduce -40.9% | 18,111 | $555K |
| Creative Planning | 0.00% | Reduce -0.9% | 16,707 | $512K |
| Cresset Asset Management, LLC | 0.00% | Add +20.9% | 15,753 | $482K |
| Virtu Financial LLC | 0.03% | New | 15,531 | $476K |
| Graham Capital Management, L.P. | 0.03% | New | 15,320 | $469K |
| Sei Investments Co. | 0.00% | New | 14,921 | $457K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -1.0% | 14,876 | $456K |
| JPMorgan Chase & Co. | 0.00% | Reduce -94.0% | 14,852 | $455K |
| California State Teachers Retirement System | 0.00% | Reduce -0.0% | 14,215 | $435K |
| Tudor Investment Corporation | 0.00% | Add +47.2% | 13,869 | $425K |
| Wells Fargo & Company | 0.00% | Reduce -58.8% | 13,743 | $421K |
| Orion Porfolio Solutions, LLC | 0.00% | New | 13,739 | $421K |
| Alps Advisors Inc. | 0.00% | Reduce -15.9% | 13,335 | $408K |
| Voya Investment Management LLC | 0.00% | Reduce -82.3% | 12,961 | $397K |
| Man Group plc | 0.00% | New | 12,859 | $394K |
| Deutsche Bank AG | 0.00% | No change | 12,681 | $388K |
| MetLife Investment Management, LLC | 0.00% | New | 11,928 | $365K |
| Tema ETFs LLC | 0.03% | Reduce -3.8% | 10,975 | $336K |
| NEOS Investment Management LLC | 0.00% | Reduce -3.8% | 10,975 | $336K |
| New York State Common Retirement Fund | 0.00% | Add +33.6% | 10,586 | $324K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | New | 10,667 | $315K |
"% of holder's portfolio" is ANAB's weight in each manager's 13F, not the share of Anaptysbio Inc. the manager owns.