Avalo TherapeuticsAVTX

13F holders, Q4 2025 (December 31)
84holders +18
30new positions
15sold out
4famous investors
$18.16avg. 13F price*

At the end of Q4 2025, 84 institutions reported holding Avalo Therapeutics Inc. (AVTX) in their 13F filings, up 18 from Q3 2025. 30 opened new positions and 15 sold out. The largest holders were BVF Inc. ($24.6M), Nantahala Capital Management, LLC ($22.4M) and Orbimed Advisors LLC ($21.6M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Avalo Therapeutics Inc.
CUSIP
05338F306
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 18Q1 2024Q2 2024: 21Q2 2024Q3 2024: 29Q3 2024Q4 2024: 33Q4 2024Q1 2025: 34Q1 2025Q2 2025: 36Q2 2025Q3 2025: 66Q3 2025Q4 2025: 84Q4 2025Q1 2026: 97Q1 2026Q2 2026: 125Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions30$57.0M
Exits15$10.2M

All 13F filers, Q3 2025 → Q4 2025: 6,659,374 shares bought and 2,305,340 shares sold, net +4,354,034 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 84 holders

BVF Inc. 0.83% Add +0.0% 1,355,257 $24.6M
Nantahala Capital Management, LLC 1.34% No change 1,235,000 $22.4M
Orbimed Advisors LLC 0.44% Reduce -12.0% 1,187,300 $21.6M
Affinity Asset Advisors, LLC 1.41% Add +4.5% 1,051,054 $19.1M
Caligan Partners LP 1.47% Add +5.8% 881,533 $16.0M
Vanguard Group Inc. 0.00% Add +16.1% 804,084 $14.6M
Ra Capital Management, L.P. 0.12% No change 662,968 $12.0M
Millennium Management 0.01% Add +380.2% 659,979 $12.0M
Point72 Asset Management 0.02% Reduce -40.5% 627,502 $11.4M
Bank of America Corp. 0.00% Add +2.6% 621,350 $11.3M
Adage Capital Partners Gp, L.L.C. 0.02% Add +112.5% 550,000 $10.0M
Silverarc Capital Management, LLC 1.38% Reduce -27.3% 524,436 $9.5M
Marshall Wace, LLP 0.01% Add +806.2% 507,550 $9.2M
Commodore Capital LP 0.58% No change 483,000 $8.8M
TCG Crossover Management, LLC 0.29% No change 483,000 $8.8M
UBS Group AG 0.00% Add +956.9% 477,816 $8.7M
Jennison Associates LLC 0.01% New 475,625 $8.6M
Soleus Capital Management, L.P. 0.34% New 441,978 $8.0M
Balyasny Asset Management L.P. 0.02% Reduce -46.3% 439,312 $8.0M
Citadel Advisors 0.01% Reduce -12.9% 419,491 $7.6M
Patient Square Capital LP 1.21% Add +212.0% 311,966 $5.7M
BlackRock, Inc. 0.00% Add +87.7% 289,571 $5.3M
Boxer Capital Management, LLC 1.09% Add +120.0% 275,000 $5.0M
Morgan Stanley 0.00% Add +2648970.0% 264,907 $4.8M
Velan Capital Investment Management LP 2.79% No change 263,642 $4.8M
FMR LLC 0.00% New 220,300 $4.0M
Ameriprise Financial Inc. 0.00% Add +2.1% 217,974 $4.0M
Jain Global LLC 0.04% New 217,292 $3.9M
Susquehanna International Group, LLP 0.01% Add +345.1% 210,994 $3.8M
Boothbay Fund Management, LLC 0.10% Reduce -11.5% 202,127 $3.7M
BNP Paribas Financial Markets 0.00% Add +3954840.0% 197,747 $3.6M
SummitTX Capital, L.P. 0.11% New 195,873 $3.6M
Nan Fung Trinity (hk) Ltd. 0.27% New 189,000 $3.4M
Jane Street Group, LLC 0.00% New 178,855 $3.2M
Geode Capital Management, LLC 0.00% Add +59.5% 166,152 $3.0M
Superstring Capital Management LP 1.49% Reduce -18.5% 153,313 $2.8M
Deutsche Bank AG 0.00% New 150,000 $2.7M
Two Sigma Investments, LP 0.00% Add +201.0% 148,237 $2.7M
Perceptive Advisors LLC 0.05% No change 139,667 $2.5M
Stempoint Capital LP 0.42% New 135,552 $2.5M
Moody Aldrich Partners LLC 0.45% New 133,231 $2.4M
Squadron Capital Management LLC 1.05% — 130,000 $2.4M
Great Point Partners LLC 0.73% New 124,666 $2.3M
Barclays PLC 0.00% Add +1032.2% 105,814 $1.9M
HighVista Strategies LLC 0.45% Add +244.3% 95,631 $1.7M
Aberdeen Group plc 0.00% Add +31.1% 95,426 $1.7M
Fred Alger Management, LLC 0.01% New 80,092 $1.5M
State Street Corp. 0.00% Add +74.4% 79,254 $1.4M
Sio Capital Management, LLC 0.22% No change 72,173 $1.3M
Goldman Sachs Group Inc. 0.00% New 65,313 $1.2M
Qube Research & Technologies Ltd 0.00% New 64,463 $1.2M
Seven Fleet Capital Management LP 0.78% — 63,343 $1.2M
683 Capital Management, LLC 0.09% New 56,850 $1.0M
Quadrature Capital Ltd 0.01% Reduce -3.5% 53,044 $963K
Caption Management, LLC 0.04% New 52,641 $956K
Woodline Partners LP 0.00% New 52,041 $945K
Atom Investors LP 0.07% New 51,194 $930K
Two Sigma Advisers, LP 0.00% New 49,400 $897K
JPMorgan Chase & Co. 0.00% Add +2724.6% 44,431 $807K
Walleye Capital LLC 0.00% Reduce -6.8% 41,693 $757K
Artia Global Partners LP 0.12% New 41,570 $755K
Squarepoint Ops LLC 0.00% New 40,854 $742K
XTX Topco Ltd 0.02% Add +190.0% 40,458 $735K
ExodusPoint Capital Management, LP 0.01% New 32,267 $586K
Northern Trust Corp. 0.00% Add +73.4% 32,204 $585K
Ikarian Capital, LLC 0.07% Reduce -80.5% 31,106 $565K
Glenmede Trust Co. NA 0.00% — 20,450 $371K
OMERS ADMINISTRATION Corp 0.00% New 19,600 $356K
Renaissance Technologies 0.00% Reduce -81.5% 18,300 $332K
Hudson Bay Capital Management LP 0.00% New 16,771 $305K
Envestnet Asset Management Inc. 0.00% New 16,039 $291K
Persistent Asset Partners Ltd 0.13% New 15,087 $274K
Jump Financial, LLC 0.00% New 13,092 $238K
Tower Research Capital LLC (TRC) 0.00% Add +33503.8% 8,737 $159K
Belvedere Trading LLC 0.02% New 4,526 $82K
US Bancorp \de 0.00% New 2,733 $50K
PFS Partners, LLC 0.02% Add +100.0% 2,000 $36K
Acadian Asset Management LLC 0.00% New 1,471 $26K
Citigroup Inc. 0.00% Add +185.8% 1,143 $21K
Group One Trading LLC 0.00% Reduce -99.6% 1 $18
Osaic Holdings, Inc. 0.00% Reduce -50.0% 1 $18
Parallel Advisors, LLC 0.00% No change 1 $18
Key Financial Inc 0.00% No change 1 $18
Activest Wealth Management 0.00% No change 1 $18

"% of holder's portfolio" is AVTX's weight in each manager's 13F, not the share of Avalo Therapeutics Inc. the manager owns.