Axsome TherapeuticsAXSM
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 353 institutions reported holding Axsome Therapeutics Inc. (AXSM) in their 13F filings, up 61 from Q4 2024. 90 opened new positions and 28 sold out. The largest holders were Vanguard Group Inc. ($452.2M), BlackRock, Inc. ($411.1M) and RTW Investments, LP ($340.9M). 8 famous investors held it, including David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Axsome Therapeutics Inc.
- CUSIP
- 05464T104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 90 | $326.4M |
| Exits | 28 | $224.8M |
All 13F filers, Q4 2024 → Q1 2025: 7,925,644 shares bought and 7,855,487 shares sold, net +70,157 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 353 holders
| Vanguard Group Inc. | 0.01% | Reduce -0.7% | 3,876,942 | $452.2M |
| BlackRock, Inc. | 0.01% | Reduce -0.3% | 3,524,411 | $411.1M |
| RTW Investments, LP | 5.21% | Reduce -27.9% | 2,922,729 | $340.9M |
| BVF Inc. | 8.03% | Add +21.8% | 1,690,221 | $197.1M |
| FMR LLC | 0.01% | Add +24.7% | 1,247,231 | $145.5M |
| Macquarie Group Ltd. | 0.14% | Add +1.3% | 976,260 | $113.9M |
| Geode Capital Management, LLC | 0.01% | Add +2.5% | 934,853 | $109.1M |
| State Street Corp. | 0.00% | Reduce -4.3% | 906,020 | $105.7M |
| Invesco Ltd. | 0.02% | Add +23.8% | 857,001 | $100.0M |
| Fairmount Funds Management LLC | 14.75% | Reduce -44.5% | 815,176 | $95.1M |
| Eventide Asset Management, LLC | 1.73% | Reduce -10.1% | 744,850 | $86.9M |
| Wellington Management Group LLP | 0.02% | Add +4.5% | 703,279 | $82.0M |
| Alethea Capital Management, LLC | 58.07% | Reduce -9.1% | 667,368 | $77.8M |
| Assenagon Asset Management S.A. | 0.13% | Add +16852.7% | 627,418 | $73.2M |
| PFM Health Sciences, LP | 5.12% | Add +19.1% | 556,545 | $64.9M |
| D. E. Shaw & Co. | 0.08% | Add +2591.8% | 547,665 | $63.9M |
| Bank of America Corp. | 0.01% | Add +161.0% | 533,902 | $62.3M |
| Man Group plc | 0.18% | Add +214.1% | 513,221 | $59.9M |
| Morgan Stanley | 0.00% | Reduce -20.7% | 457,416 | $53.3M |
| Norges Bank | 0.01% | Add +8.6% | 437,497 | $51.0M |
| Nuveen, LLC | 0.01% | — | 413,141 | $48.2M |
| Northern Trust Corp. | 0.01% | Add +2.1% | 410,969 | $47.9M |
| Orbimed Advisors LLC | 1.08% | New | 386,700 | $45.1M |
| 1832 Asset Management L.P. | 0.08% | New | 363,200 | $42.4M |
| Perceptive Advisors LLC | 1.47% | Reduce -46.5% | 355,107 | $41.4M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +2.8% | 337,246 | $39.3M |
| Pictet Asset Management Holding SA | 0.04% | Add +7022.8% | 333,205 | $38.9M |
| Woodline Partners LP | 0.23% | Reduce -25.6% | 304,084 | $35.5M |
| Goldman Sachs Group Inc. | 0.01% | Add +38.7% | 301,718 | $35.2M |
| Principal Financial Group Inc. | 0.02% | Add +42.8% | 295,671 | $34.5M |
| UBS Group AG | 0.01% | Add +95.9% | 288,647 | $33.7M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 6.87% | Add +746.7% | 285,494 | $33.3M |
| Loomis Sayles & Co. L P | 0.05% | Reduce -2.0% | 284,170 | $33.1M |
| Qube Research & Technologies Ltd | 0.05% | Add +81.1% | 282,376 | $32.9M |
| T. Rowe Price Investment Management, Inc. | 0.02% | New | 266,997 | $31.1M |
| Cormorant Asset Management, LP | 2.21% | Reduce -23.1% | 250,000 | $29.2M |
| Voloridge Investment Management, LLC | 0.10% | New | 235,383 | $27.5M |
| Millennium Management | 0.03% | Add +5441.9% | 235,311 | $27.4M |
| Franklin Resources Inc. | 0.01% | Add +24.3% | 226,515 | $26.4M |
| Driehaus Capital Management LLC | 0.24% | New | 214,139 | $25.0M |
| BNP Paribas Financial Markets | 0.02% | Reduce -1.6% | 182,632 | $21.3M |
| MetLife Investment Management, LLC | 0.11% | Add +703.3% | 178,955 | $20.9M |
| Cubist Systematic Strategies, LLC | 0.27% | Add +52.1% | 177,814 | $20.7M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.09% | Add +139.4% | 175,942 | $20.5M |
| Sofinnova Investments, Inc. | 1.54% | Reduce -64.3% | 175,317 | $20.4M |
| Raymond James Financial Inc. | 0.01% | Reduce -11.2% | 155,075 | $18.1M |
| Two Sigma Advisers, LP | 0.04% | Add +2274.6% | 149,600 | $17.4M |
| Squarepoint Ops LLC | 0.04% | Add +58.3% | 141,597 | $16.5M |
| Granite Investment Partners, LLC | 0.82% | Add +51.4% | 138,719 | $16.2M |
| Renaissance Technologies | 0.02% | New | 134,400 | $15.7M |
| Bank of New York Mellon Corp | 0.00% | Reduce -2.6% | 131,023 | $15.3M |
| US Bancorp \de | 0.02% | Reduce -0.6% | 130,295 | $15.2M |
| Point72 Asset Management | 0.04% | Reduce -31.8% | 126,193 | $14.7M |
| JPMorgan Chase & Co. | 0.00% | Reduce -38.2% | 124,783 | $14.6M |
| First Turn Management, LLC | 2.78% | Reduce -38.5% | 118,179 | $13.8M |
| WCM Investment Management, LLC | 0.03% | Reduce -0.0% | 111,948 | $13.3M |
| Rhenman & Partners Asset Management AB | 1.47% | Reduce -10.6% | 109,600 | $12.8M |
| Iridian Asset Management LLC | 3.89% | Reduce -15.0% | 106,312 | $12.4M |
| Tri Locum Partners LP | 6.06% | Reduce -59.5% | 101,240 | $11.8M |
| Affinity Asset Advisors, LLC | 1.93% | Add +33.3% | 100,000 | $11.7M |
| Voya Investment Management LLC | 0.02% | Reduce -3.6% | 99,000 | $11.5M |
| Bellevue Group AG | 0.25% | Reduce -18.9% | 96,407 | $11.2M |
| Deutsche Bank AG | 0.00% | Reduce -21.2% | 94,980 | $11.1M |
| Jump Financial, LLC | 0.17% | New | 92,640 | $10.8M |
| Jane Street Group, LLC | 0.02% | Add +14.9% | 90,141 | $10.5M |
| Cannell & Spears LLC | 0.21% | Add +2.6% | 84,264 | $9.8M |
| Citadel Advisors | 0.01% | Reduce -83.1% | 83,786 | $9.8M |
| HSBC Holdings PLC | 0.01% | Reduce -38.9% | 83,572 | $9.7M |
| Candriam S.C.A. | 0.06% | New | 79,930 | $9.3M |
| Avidity Partners Management LP | 1.85% | Reduce -59.0% | 77,000 | $9.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +29.9% | 74,892 | $8.7M |
| Atika Capital Management LLC | 1.32% | Add +235.0% | 73,700 | $8.6M |
| Ally Bridge Group (NY) LLC | 7.58% | Add +8.2% | 72,113 | $8.4M |
| Edgestream Partners, L.P. | 0.28% | New | 70,086 | $8.2M |
| Marshall Wace, LLP | 0.01% | Reduce -46.0% | 68,696 | $8.0M |
| Clearbridge Investments, LLC | 0.01% | Reduce -39.7% | 68,164 | $7.9M |
| IFP Advisors, Inc | 0.24% | Add +0.4% | 68,114 | $7.9M |
| Aberdeen Group plc | 0.01% | Reduce -11.4% | 63,954 | $7.5M |
| Van Eck Associates Corp. | 0.01% | New | 62,995 | $7.3M |
| Moody Aldrich Partners LLC | 1.52% | Add +38.1% | 62,339 | $7.3M |
| DNB Asset Management AS | 0.03% | Reduce -16.6% | 61,528 | $7.2M |
| Alliancebernstein L.P. | 0.00% | Add +31.9% | 61,471 | $7.2M |
| Swiss National Bank | 0.01% | Reduce -0.7% | 61,000 | $7.1M |
| Peregrine Capital Management LLC | 0.23% | Reduce -31.5% | 59,721 | $7.0M |
| Readystate Asset Management LP | 0.63% | New | 59,553 | $6.9M |
| Hennion & Walsh Asset Management, Inc. | 0.31% | Add +2.5% | 59,273 | $6.9M |
| AQR Capital Management | 0.01% | Add +52.7% | 58,363 | $6.8M |
| HB Wealth Management, LLC | 0.05% | New | 55,030 | $6.4M |
| Rhumbline Advisers | 0.01% | Add +6.9% | 54,760 | $6.4M |
| Privium Fund Management B.V. | 1.60% | Reduce -15.3% | 52,732 | $6.2M |
| ExodusPoint Capital Management, LP | 0.08% | New | 52,683 | $6.1M |
| Blair William & Co. | 0.02% | Reduce -3.4% | 52,529 | $6.1M |
| Barclays PLC | 0.00% | Reduce -47.1% | 51,870 | $6.0M |
| Susquehanna International Group, LLP | 0.01% | Add +175.6% | 51,726 | $6.0M |
| PDT Partners, LLC | 0.42% | Add +1120.5% | 51,199 | $6.0M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | New | 50,096 | $5.8M |
| Baldwin Wealth Partners LLC | 0.41% | No change | 49,570 | $5.8M |
| Lindbrook Capital, LLC | 0.52% | Reduce -22.7% | 48,041 | $5.6M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | Reduce -20.0% | 48,000 | $5.6M |
| Aquatic Capital Management LLC | 0.14% | Add +5154.3% | 47,446 | $5.5M |
"% of holder's portfolio" is AXSM's weight in each manager's 13F, not the share of Axsome Therapeutics Inc. the manager owns.