Axsome TherapeuticsAXSM

13F holders, Q1 2025 (March 31)
353holders +61
90new positions
28sold out
8famous investors
$116.63avg. 13F price*

At the end of Q1 2025, 353 institutions reported holding Axsome Therapeutics Inc. (AXSM) in their 13F filings, up 61 from Q4 2024. 90 opened new positions and 28 sold out. The largest holders were Vanguard Group Inc. ($452.2M), BlackRock, Inc. ($411.1M) and RTW Investments, LP ($340.9M). 8 famous investors held it, including David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).

Company
Axsome Therapeutics Inc.
CUSIP
05464T104
Latest filing quarter
Q2 2026

History

Number of 13F holders

0200400600 Q1 2024: 259Q1 2024Q2 2024: 257Q2 2024Q3 2024: 280Q3 2024Q4 2024: 292Q4 2024Q1 2025: 353Q1 2025Q2 2025: 348Q2 2025Q3 2025: 355Q3 2025Q4 2025: 399Q4 2025Q1 2026: 410Q1 2026Q2 2026: 505Q2 2026

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions90$326.4M
Exits28$224.8M

All 13F filers, Q4 2024 → Q1 2025: 7,925,644 shares bought and 7,855,487 shares sold, net +70,157 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 353 holders

Vanguard Group Inc. 0.01% Reduce -0.7% 3,876,942 $452.2M
BlackRock, Inc. 0.01% Reduce -0.3% 3,524,411 $411.1M
RTW Investments, LP 5.21% Reduce -27.9% 2,922,729 $340.9M
BVF Inc. 8.03% Add +21.8% 1,690,221 $197.1M
FMR LLC 0.01% Add +24.7% 1,247,231 $145.5M
Macquarie Group Ltd. 0.14% Add +1.3% 976,260 $113.9M
Geode Capital Management, LLC 0.01% Add +2.5% 934,853 $109.1M
State Street Corp. 0.00% Reduce -4.3% 906,020 $105.7M
Invesco Ltd. 0.02% Add +23.8% 857,001 $100.0M
Fairmount Funds Management LLC 14.75% Reduce -44.5% 815,176 $95.1M
Eventide Asset Management, LLC 1.73% Reduce -10.1% 744,850 $86.9M
Wellington Management Group LLP 0.02% Add +4.5% 703,279 $82.0M
Alethea Capital Management, LLC 58.07% Reduce -9.1% 667,368 $77.8M
Assenagon Asset Management S.A. 0.13% Add +16852.7% 627,418 $73.2M
PFM Health Sciences, LP 5.12% Add +19.1% 556,545 $64.9M
D. E. Shaw & Co. 0.08% Add +2591.8% 547,665 $63.9M
Bank of America Corp. 0.01% Add +161.0% 533,902 $62.3M
Man Group plc 0.18% Add +214.1% 513,221 $59.9M
Morgan Stanley 0.00% Reduce -20.7% 457,416 $53.3M
Norges Bank 0.01% Add +8.6% 437,497 $51.0M
Nuveen, LLC 0.01% — 413,141 $48.2M
Northern Trust Corp. 0.01% Add +2.1% 410,969 $47.9M
Orbimed Advisors LLC 1.08% New 386,700 $45.1M
1832 Asset Management L.P. 0.08% New 363,200 $42.4M
Perceptive Advisors LLC 1.47% Reduce -46.5% 355,107 $41.4M
Charles Schwab Investment Management Inc. 0.01% Add +2.8% 337,246 $39.3M
Pictet Asset Management Holding SA 0.04% Add +7022.8% 333,205 $38.9M
Woodline Partners LP 0.23% Reduce -25.6% 304,084 $35.5M
Goldman Sachs Group Inc. 0.01% Add +38.7% 301,718 $35.2M
Principal Financial Group Inc. 0.02% Add +42.8% 295,671 $34.5M
UBS Group AG 0.01% Add +95.9% 288,647 $33.7M
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 6.87% Add +746.7% 285,494 $33.3M
Loomis Sayles & Co. L P 0.05% Reduce -2.0% 284,170 $33.1M
Qube Research & Technologies Ltd 0.05% Add +81.1% 282,376 $32.9M
T. Rowe Price Investment Management, Inc. 0.02% New 266,997 $31.1M
Cormorant Asset Management, LP 2.21% Reduce -23.1% 250,000 $29.2M
Voloridge Investment Management, LLC 0.10% New 235,383 $27.5M
Millennium Management 0.03% Add +5441.9% 235,311 $27.4M
Franklin Resources Inc. 0.01% Add +24.3% 226,515 $26.4M
Driehaus Capital Management LLC 0.24% New 214,139 $25.0M
BNP Paribas Financial Markets 0.02% Reduce -1.6% 182,632 $21.3M
MetLife Investment Management, LLC 0.11% Add +703.3% 178,955 $20.9M
Cubist Systematic Strategies, LLC 0.27% Add +52.1% 177,814 $20.7M
Connor, Clark & Lunn Investment Management Ltd. 0.09% Add +139.4% 175,942 $20.5M
Sofinnova Investments, Inc. 1.54% Reduce -64.3% 175,317 $20.4M
Raymond James Financial Inc. 0.01% Reduce -11.2% 155,075 $18.1M
Two Sigma Advisers, LP 0.04% Add +2274.6% 149,600 $17.4M
Squarepoint Ops LLC 0.04% Add +58.3% 141,597 $16.5M
Granite Investment Partners, LLC 0.82% Add +51.4% 138,719 $16.2M
Renaissance Technologies 0.02% New 134,400 $15.7M
Bank of New York Mellon Corp 0.00% Reduce -2.6% 131,023 $15.3M
US Bancorp \de 0.02% Reduce -0.6% 130,295 $15.2M
Point72 Asset Management 0.04% Reduce -31.8% 126,193 $14.7M
JPMorgan Chase & Co. 0.00% Reduce -38.2% 124,783 $14.6M
First Turn Management, LLC 2.78% Reduce -38.5% 118,179 $13.8M
WCM Investment Management, LLC 0.03% Reduce -0.0% 111,948 $13.3M
Rhenman & Partners Asset Management AB 1.47% Reduce -10.6% 109,600 $12.8M
Iridian Asset Management LLC 3.89% Reduce -15.0% 106,312 $12.4M
Tri Locum Partners LP 6.06% Reduce -59.5% 101,240 $11.8M
Affinity Asset Advisors, LLC 1.93% Add +33.3% 100,000 $11.7M
Voya Investment Management LLC 0.02% Reduce -3.6% 99,000 $11.5M
Bellevue Group AG 0.25% Reduce -18.9% 96,407 $11.2M
Deutsche Bank AG 0.00% Reduce -21.2% 94,980 $11.1M
Jump Financial, LLC 0.17% New 92,640 $10.8M
Jane Street Group, LLC 0.02% Add +14.9% 90,141 $10.5M
Cannell & Spears LLC 0.21% Add +2.6% 84,264 $9.8M
Citadel Advisors 0.01% Reduce -83.1% 83,786 $9.8M
HSBC Holdings PLC 0.01% Reduce -38.9% 83,572 $9.7M
Candriam S.C.A. 0.06% New 79,930 $9.3M
Avidity Partners Management LP 1.85% Reduce -59.0% 77,000 $9.0M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +29.9% 74,892 $8.7M
Atika Capital Management LLC 1.32% Add +235.0% 73,700 $8.6M
Ally Bridge Group (NY) LLC 7.58% Add +8.2% 72,113 $8.4M
Edgestream Partners, L.P. 0.28% New 70,086 $8.2M
Marshall Wace, LLP 0.01% Reduce -46.0% 68,696 $8.0M
Clearbridge Investments, LLC 0.01% Reduce -39.7% 68,164 $7.9M
IFP Advisors, Inc 0.24% Add +0.4% 68,114 $7.9M
Aberdeen Group plc 0.01% Reduce -11.4% 63,954 $7.5M
Van Eck Associates Corp. 0.01% New 62,995 $7.3M
Moody Aldrich Partners LLC 1.52% Add +38.1% 62,339 $7.3M
DNB Asset Management AS 0.03% Reduce -16.6% 61,528 $7.2M
Alliancebernstein L.P. 0.00% Add +31.9% 61,471 $7.2M
Swiss National Bank 0.01% Reduce -0.7% 61,000 $7.1M
Peregrine Capital Management LLC 0.23% Reduce -31.5% 59,721 $7.0M
Readystate Asset Management LP 0.63% New 59,553 $6.9M
Hennion & Walsh Asset Management, Inc. 0.31% Add +2.5% 59,273 $6.9M
AQR Capital Management 0.01% Add +52.7% 58,363 $6.8M
HB Wealth Management, LLC 0.05% New 55,030 $6.4M
Rhumbline Advisers 0.01% Add +6.9% 54,760 $6.4M
Privium Fund Management B.V. 1.60% Reduce -15.3% 52,732 $6.2M
ExodusPoint Capital Management, LP 0.08% New 52,683 $6.1M
Blair William & Co. 0.02% Reduce -3.4% 52,529 $6.1M
Barclays PLC 0.00% Reduce -47.1% 51,870 $6.0M
Susquehanna International Group, LLP 0.01% Add +175.6% 51,726 $6.0M
PDT Partners, LLC 0.42% Add +1120.5% 51,199 $6.0M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% New 50,096 $5.8M
Baldwin Wealth Partners LLC 0.41% No change 49,570 $5.8M
Lindbrook Capital, LLC 0.52% Reduce -22.7% 48,041 $5.6M
Adage Capital Partners Gp, L.L.C. 0.01% Reduce -20.0% 48,000 $5.6M
Aquatic Capital Management LLC 0.14% Add +5154.3% 47,446 $5.5M

"% of holder's portfolio" is AXSM's weight in each manager's 13F, not the share of Axsome Therapeutics Inc. the manager owns.

Show all 353 holders