Axsome TherapeuticsAXSM
13F holders, Q4 2025 (December 31)399holders +44
65new positions
33sold out
7famous investors
$182.32avg. 13F price*
At the end of Q4 2025, 399 institutions reported holding Axsome Therapeutics Inc. (AXSM) in their 13F filings, up 44 from Q3 2025. 65 opened new positions and 33 sold out. The largest holders were Vanguard Group Inc. ($760.7M), BlackRock, Inc. ($714.8M) and T. Rowe Price Associates Inc. ($275.8M). 7 famous investors held it, including David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ray Dalio (0.0% of Bridgewater Associates's portfolio).
- Company
- Axsome Therapeutics Inc.
- CUSIP
- 05464T104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 65 | $97.0M |
| Exits | 33 | $268.1M |
All 13F filers, Q3 2025 → Q4 2025: 4,524,857 shares bought and 5,568,135 shares sold, net −1,043,278 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 399 holders
| Vanguard Group Inc. | 0.01% | Reduce -0.4% | 4,164,818 | $760.7M |
| BlackRock, Inc. | 0.01% | Add +3.2% | 3,913,543 | $714.8M |
| T. Rowe Price Associates Inc. | 0.03% | Add +45.5% | 1,509,870 | $275.8M |
| Invesco Ltd. | 0.02% | Add +28.6% | 1,273,494 | $232.6M |
| Wellington Management Group LLP | 0.04% | Reduce -8.5% | 1,221,656 | $223.1M |
| FMR LLC | 0.01% | Add +27.4% | 1,181,622 | $215.8M |
| Deep Track Capital, LP | 4.79% | Add +27.8% | 1,150,000 | $210.0M |
| Geode Capital Management, LLC | 0.01% | Add +1.3% | 1,010,249 | $184.5M |
| Nomura Asset Management International Inc. | 0.27% | — | 989,447 | $180.7M |
| State Street Corp. | 0.01% | Add +1.6% | 958,150 | $175.0M |
| RTW Investments, LP | 1.62% | Reduce -20.6% | 888,001 | $162.2M |
| Alethea Capital Management, LLC | 59.30% | Reduce -0.3% | 668,710 | $122.1M |
| Bank of America Corp. | 0.01% | Add +71.1% | 618,033 | $112.9M |
| Eventide Asset Management, LLC | 1.63% | Reduce -23.5% | 571,226 | $104.2M |
| D. E. Shaw & Co. | 0.08% | Add +85.3% | 549,113 | $100.3M |
| Norges Bank | 0.01% | — | 495,456 | $90.5M |
| Morgan Stanley | 0.01% | Add +19.9% | 491,201 | $89.7M |
| Assenagon Asset Management S.A. | 0.13% | Add +58.8% | 467,982 | $85.5M |
| Pictet Asset Management Holding SA | 0.08% | Add +20.4% | 436,063 | $79.6M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +5.4% | 402,700 | $73.5M |
| Northern Trust Corp. | 0.01% | Reduce -4.7% | 390,431 | $71.3M |
| Adage Capital Partners Gp, L.L.C. | 0.10% | Reduce -17.4% | 367,578 | $67.1M |
| Hood River Capital Management LLC | 0.73% | Add +1.7% | 366,176 | $66.9M |
| Principal Financial Group Inc. | 0.03% | Reduce -1.4% | 363,114 | $66.3M |
| UBS Group AG | 0.01% | Add +67.3% | 355,318 | $64.9M |
| Nuveen, LLC | 0.02% | Add +17.1% | 349,209 | $63.8M |
| Franklin Resources Inc. | 0.02% | Add +19.9% | 342,573 | $62.6M |
| Qube Research & Technologies Ltd | 0.09% | Reduce -0.1% | 325,440 | $59.4M |
| Marshall Wace, LLP | 0.06% | Reduce -15.2% | 320,568 | $58.5M |
| Loomis Sayles & Co. L P | 0.07% | Reduce -4.5% | 315,391 | $57.6M |
| BNP Paribas Financial Markets | 0.04% | Add +60.1% | 304,388 | $55.6M |
| Goldman Sachs Group Inc. | 0.01% | Add +34.3% | 300,906 | $55.0M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 4.52% | Reduce -14.6% | 278,835 | $50.9M |
| Bank of New York Mellon Corp | 0.01% | Add +0.7% | 255,097 | $46.6M |
| Orbimed Advisors LLC | 0.95% | Reduce -52.4% | 253,121 | $46.2M |
| PFM Health Sciences, LP | 4.72% | Reduce -52.6% | 251,562 | $45.9M |
| JPMorgan Chase & Co. | 0.00% | Reduce -6.9% | 233,191 | $42.6M |
| Man Group plc | 0.08% | Reduce -20.6% | 228,641 | $41.8M |
| Driehaus Capital Management LLC | 0.27% | Reduce -1.3% | 220,518 | $40.3M |
| Vestal Point Capital, LP | 1.41% | Add +40.0% | 210,000 | $38.4M |
| First Turn Management, LLC | 4.32% | Add +35.6% | 206,921 | $37.8M |
| Citigroup Inc. | 0.03% | Add +43.7% | 204,104 | $37.3M |
| Tri Locum Partners LP | 4.78% | Reduce -31.0% | 201,627 | $36.8M |
| Two Sigma Advisers, LP | 0.07% | New | 188,500 | $34.4M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.09% | Reduce -9.9% | 188,258 | $34.4M |
| Voya Investment Management LLC | 0.04% | Add +52.0% | 173,301 | $31.7M |
| Renaissance Technologies | 0.05% | Add +13.3% | 170,000 | $31.0M |
| MetLife Investment Management, LLC | 0.15% | Reduce -16.4% | 164,871 | $30.1M |
| Frontier Capital Management Co. LLC | 0.31% | Add +24.8% | 157,691 | $28.8M |
| Squarepoint Ops LLC | 0.06% | No change | 155,000 | $28.3M |
| Woodline Partners LP | 0.11% | Reduce -54.5% | 150,864 | $27.6M |
| Algert Global LLC | 0.43% | Add +238.4% | 149,392 | $27.3M |
| Perceptive Advisors LLC | 0.50% | No change | 148,900 | $27.2M |
| Two Sigma Investments, LP | 0.04% | Add +1674.1% | 145,597 | $26.6M |
| Citadel Advisors | 0.02% | Reduce -12.8% | 138,213 | $25.2M |
| Jane Street Group, LLC | 0.03% | Add +4.9% | 137,283 | $25.1M |
| Raymond James Financial Inc. | 0.01% | Reduce -5.4% | 150,098 | $24.8M |
| US Bancorp \de | 0.03% | Reduce -0.4% | 130,985 | $23.9M |
| Manufacturers Life Insurance Company, The | 0.02% | Add +0.9% | 133,884 | $23.7M |
| Rhenman & Partners Asset Management AB | 1.96% | Reduce -33.6% | 114,800 | $21.0M |
| Voleon Capital Management LP | 0.43% | Add +558.4% | 110,179 | $20.1M |
| Emerald Advisers, LLC | 0.61% | Reduce -0.8% | 108,082 | $19.7M |
| AQR Capital Management | 0.01% | Reduce -12.8% | 103,418 | $18.9M |
| Canada Pension Plan Investment Board | 0.01% | Add +60.3% | 103,200 | $18.8M |
| DNB Asset Management AS | 0.06% | Reduce -0.9% | 101,102 | $18.5M |
| Ameriprise Financial Inc. | 0.00% | Reduce -7.7% | 99,916 | $18.2M |
| Deutsche Bank AG | 0.01% | Add +1.6% | 98,257 | $17.9M |
| Aberdeen Group plc | 0.03% | Add +2.9% | 97,413 | $17.8M |
| Royce & Associates LP | 0.17% | Add +67.8% | 94,017 | $17.2M |
| Nicholas Investment Partners, LP | 1.38% | Add +88.2% | 91,564 | $16.7M |
| WCM Investment Management, LLC | 0.03% | Reduce -6.4% | 112,058 | $16.7M |
| M&G PLC | 0.09% | New | 90,328 | $16.5M |
| Wells Fargo & Company | 0.00% | Add +62.2% | 89,661 | $16.4M |
| Federated Hermes, Inc. | 0.03% | Add +52.4% | 87,280 | $15.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.6% | 87,249 | $15.9M |
| Granite Investment Partners, LLC | 0.92% | Reduce -4.1% | 84,894 | $15.5M |
| Cannell & Spears LLC | 0.29% | Add +0.0% | 84,154 | $15.4M |
| Barclays PLC | 0.01% | Add +6.6% | 76,853 | $14.0M |
| Cormorant Asset Management, LP | 0.78% | Reduce -25.0% | 75,000 | $13.7M |
| Iridian Asset Management LLC | 4.96% | Reduce -11.7% | 73,783 | $13.5M |
| Summit Financial, LLC | 0.19% | Reduce -8.9% | 70,628 | $12.9M |
| Neuberger Berman Group LLC | 0.01% | Reduce -23.8% | 69,483 | $12.7M |
| Swiss National Bank | 0.01% | Add +3.1% | 68,900 | $12.6M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | Add +1.4% | 68,858 | $12.6M |
| Emerald Mutual Fund Advisers Trust | 0.60% | Add +3.2% | 67,608 | $12.3M |
| Axiom Investors LLC | 0.10% | Add +28.7% | 63,390 | $11.6M |
| IFP Advisors, Inc | 0.26% | Reduce -1.4% | 62,448 | $11.4M |
| Walleye Capital LLC | 0.07% | Add +11920.0% | 60,100 | $11.0M |
| Privium Fund Management B.V. | 1.91% | Add +7.9% | 56,878 | $10.4M |
| Edgestream Partners, L.P. | 0.29% | Add +207.2% | 56,364 | $10.3M |
| HighTower Advisors, LLC | 0.01% | Reduce -2.0% | 55,972 | $10.2M |
| Atika Capital Management LLC | 1.41% | Add +13.3% | 55,500 | $10.1M |
| Alliancebernstein L.P. | 0.00% | Reduce -15.7% | 53,140 | $9.7M |
| Rhumbline Advisers | 0.01% | Reduce -14.1% | 52,233 | $9.5M |
| Trexquant Investment LP | 0.08% | Add +416.1% | 49,136 | $9.0M |
| Baldwin Wealth Partners LLC | 0.57% | No change | 48,570 | $8.9M |
| Sei Investments Co. | 0.01% | Reduce -1.1% | 47,600 | $8.7M |
| Bridgewater Associates | 0.03% | New | 47,444 | $8.7M |
| Blair William & Co. | 0.02% | Reduce -6.5% | 46,840 | $8.6M |
| Peregrine Capital Management LLC | 0.26% | Reduce -27.7% | 46,633 | $8.5M |
"% of holder's portfolio" is AXSM's weight in each manager's 13F, not the share of Axsome Therapeutics Inc. the manager owns.