Axsome TherapeuticsAXSM
13F holders, Q3 2025 (September 30)355holders +7
45new positions
39sold out
6famous investors
$121.39avg. 13F price*
At the end of Q3 2025, 355 institutions reported holding Axsome Therapeutics Inc. (AXSM) in their 13F filings, up 7 from Q2 2025. 45 opened new positions and 39 sold out. The largest holders were Vanguard Group Inc. ($507.7M), BlackRock, Inc. ($460.4M) and Wellington Management Group LLP ($162.1M). 6 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Axsome Therapeutics Inc.
- CUSIP
- 05464T104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 45 | $59.8M |
| Exits | 39 | $56.1M |
All 13F filers, Q2 2025 → Q3 2025: 4,567,440 shares bought and 4,795,216 shares sold, net −227,776 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 355 holders
| Vanguard Group Inc. | 0.01% | Add +6.0% | 4,180,646 | $507.7M |
| BlackRock, Inc. | 0.01% | Reduce -1.1% | 3,790,929 | $460.4M |
| Wellington Management Group LLP | 0.03% | Add +84.1% | 1,334,560 | $162.1M |
| RTW Investments, LP | 1.67% | Reduce -26.2% | 1,118,883 | $135.9M |
| Macquarie Group Ltd. | 0.15% | Reduce -4.7% | 1,084,536 | $131.7M |
| T. Rowe Price Associates Inc. | 0.01% | Add +69.3% | 1,037,448 | $126.0M |
| Geode Capital Management, LLC | 0.01% | Add +0.8% | 997,700 | $121.2M |
| Invesco Ltd. | 0.02% | Add +73.3% | 990,557 | $120.3M |
| State Street Corp. | 0.00% | Reduce -1.6% | 942,960 | $114.5M |
| FMR LLC | 0.01% | Reduce -5.0% | 927,883 | $112.7M |
| Deep Track Capital, LP | 3.05% | Add +12.3% | 900,000 | $109.3M |
| Fairmount Funds Management LLC | 8.91% | No change | 815,176 | $99.0M |
| Eventide Asset Management, LLC | 1.49% | Add +2.9% | 746,398 | $90.6M |
| Alethea Capital Management, LLC | 52.44% | Add +0.5% | 670,883 | $81.5M |
| Orbimed Advisors LLC | 1.55% | Add +24.3% | 531,800 | $64.6M |
| PFM Health Sciences, LP | 5.57% | Add +9.8% | 530,332 | $64.4M |
| BVF Inc. | 2.40% | Reduce -71.2% | 486,757 | $59.1M |
| Adage Capital Partners Gp, L.L.C. | 0.09% | Reduce -0.5% | 445,000 | $54.0M |
| Morgan Stanley | 0.00% | Reduce -8.6% | 409,580 | $49.7M |
| Northern Trust Corp. | 0.01% | Add +0.0% | 409,535 | $49.7M |
| Sofinnova Investments, Inc. | 2.93% | Add +320.4% | 393,499 | $47.8M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +7.1% | 382,047 | $46.4M |
| Marshall Wace, LLP | 0.05% | Add +566.5% | 378,024 | $45.9M |
| Principal Financial Group Inc. | 0.02% | Add +3.6% | 368,434 | $44.7M |
| Pictet Asset Management Holding SA | 0.04% | Reduce -12.1% | 362,138 | $44.0M |
| Bank of America Corp. | 0.00% | Reduce -52.0% | 361,261 | $43.9M |
| Hood River Capital Management LLC | 0.52% | Reduce -3.0% | 359,957 | $43.7M |
| Woodline Partners LP | 0.19% | Add +0.2% | 331,864 | $40.3M |
| Loomis Sayles & Co. L P | 0.05% | Add +19.0% | 330,125 | $40.1M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 3.06% | No change | 326,318 | $39.6M |
| Qube Research & Technologies Ltd | 0.06% | Reduce -16.9% | 325,626 | $39.5M |
| Nuveen, LLC | 0.01% | Add +5.4% | 298,341 | $36.2M |
| D. E. Shaw & Co. | 0.03% | Add +47.6% | 296,287 | $36.0M |
| Assenagon Asset Management S.A. | 0.05% | Add +62.9% | 294,771 | $35.8M |
| Tri Locum Partners LP | 8.16% | Add +85.1% | 292,137 | $35.5M |
| Man Group plc | 0.07% | Reduce -45.2% | 287,908 | $35.0M |
| Franklin Resources Inc. | 0.01% | Add +2.5% | 285,598 | $34.7M |
| T. Rowe Price Investment Management, Inc. | 0.02% | Add +10.2% | 274,014 | $33.3M |
| Bank of New York Mellon Corp | 0.01% | Add +24.4% | 253,263 | $30.8M |
| JPMorgan Chase & Co. | 0.00% | Add +33.4% | 250,513 | $30.4M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -1.8% | 224,139 | $27.2M |
| Driehaus Capital Management LLC | 0.19% | Add +0.1% | 223,408 | $27.1M |
| UBS Group AG | 0.01% | Reduce -64.3% | 212,451 | $25.8M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.08% | Reduce -7.0% | 209,069 | $25.4M |
| MetLife Investment Management, LLC | 0.12% | Add +7.1% | 197,318 | $24.0M |
| BNP Paribas Financial Markets | 0.02% | Add +2.0% | 190,106 | $23.1M |
| Rhenman & Partners Asset Management AB | 2.32% | Add +90.3% | 172,800 | $21.0M |
| Raymond James Financial Inc. | 0.01% | Reduce -1.7% | 158,689 | $19.3M |
| Citadel Advisors | 0.02% | Add +1063.2% | 158,406 | $19.2M |
| Squarepoint Ops LLC | 0.04% | Reduce -4.9% | 155,000 | $18.8M |
| First Turn Management, LLC | 2.78% | Add +5.7% | 152,614 | $18.5M |
| Vestal Point Capital, LP | 0.83% | New | 150,000 | $18.2M |
| Renaissance Technologies | 0.02% | Add +8.2% | 150,000 | $18.2M |
| Perceptive Advisors LLC | 0.53% | Reduce -25.0% | 148,900 | $18.1M |
| Citigroup Inc. | 0.01% | Add +67.0% | 142,013 | $17.2M |
| Blackstone Inc. | 0.07% | No change | 140,000 | $17.0M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -0.8% | 132,717 | $16.1M |
| US Bancorp \de | 0.02% | Add +0.5% | 131,533 | $16.0M |
| Jane Street Group, LLC | 0.02% | New | 130,845 | $15.9M |
| Frontier Capital Management Co. LLC | 0.14% | Add +338.2% | 126,382 | $15.3M |
| AQR Capital Management | 0.01% | Reduce -7.2% | 118,656 | $14.4M |
| WCM Investment Management, LLC | 0.03% | Add +0.0% | 119,696 | $14.1M |
| Voya Investment Management LLC | 0.02% | Reduce -18.1% | 114,050 | $13.9M |
| Emerald Advisers, LLC | 0.42% | Reduce -3.1% | 108,942 | $13.2M |
| Ameriprise Financial Inc. | 0.00% | Add +54.4% | 108,236 | $13.1M |
| DNB Asset Management AS | 0.05% | Add +33.1% | 101,981 | $12.4M |
| HSBC Holdings PLC | 0.01% | Add +2.9% | 101,001 | $12.3M |
| Cormorant Asset Management, LP | 0.84% | No change | 100,000 | $12.1M |
| Deutsche Bank AG | 0.00% | Add +4.1% | 96,692 | $11.7M |
| Aberdeen Group plc | 0.02% | Add +15.5% | 94,648 | $11.5M |
| Neuberger Berman Group LLC | 0.01% | Add +29.1% | 91,178 | $11.1M |
| Granite Investment Partners, LLC | 0.61% | Reduce -31.1% | 88,558 | $10.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -35.4% | 86,691 | $10.5M |
| Cannell & Spears LLC | 0.19% | No change | 84,151 | $10.2M |
| Iridian Asset Management LLC | 3.99% | Reduce -8.9% | 83,553 | $10.1M |
| Summit Financial, LLC | 0.14% | New | 77,540 | $9.4M |
| Barclays PLC | 0.00% | Reduce -26.1% | 72,067 | $8.8M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +30.7% | 67,902 | $8.2M |
| Swiss National Bank | 0.00% | Add +2.5% | 66,800 | $8.1M |
| Emerald Mutual Fund Advisers Trust | 0.41% | Add +2.5% | 65,505 | $8.0M |
| Peregrine Capital Management LLC | 0.24% | Reduce -12.2% | 64,521 | $7.8M |
| Canada Pension Plan Investment Board | 0.01% | Reduce -10.9% | 64,400 | $7.8M |
| IFP Advisors, Inc | 0.20% | Reduce -1.1% | 63,313 | $7.7M |
| Alliancebernstein L.P. | 0.00% | Add +37.1% | 63,065 | $7.7M |
| Rhumbline Advisers | 0.01% | Reduce -1.7% | 60,778 | $7.4M |
| Clearbridge Investments, LLC | 0.01% | Add +2.4% | 57,667 | $7.0M |
| Federated Hermes, Inc. | 0.01% | Add +1.4% | 57,285 | $7.0M |
| HighTower Advisors, LLC | 0.01% | Add +421.0% | 57,115 | $6.9M |
| Royce & Associates LP | 0.07% | Add +117.6% | 56,036 | $6.8M |
| Wells Fargo & Company | 0.00% | Reduce -0.8% | 55,273 | $6.7M |
| Privium Fund Management B.V. | 1.15% | No change | 52,732 | $6.4M |
| Bellevue Group AG | 0.13% | Reduce -7.0% | 52,335 | $6.4M |
| Moody Aldrich Partners LLC | 1.19% | Reduce -16.2% | 51,476 | $6.3M |
| Susquehanna International Group, LLP | 0.01% | Reduce -52.6% | 50,246 | $6.1M |
| Blair William & Co. | 0.02% | Add +1.2% | 50,077 | $6.1M |
| Axiom Investors LLC | 0.04% | Add +81.7% | 49,253 | $6.0M |
| Atika Capital Management LLC | 0.51% | Add +6.2% | 49,000 | $6.0M |
| Nicholas Investment Partners, LP | 0.52% | Add +15.4% | 48,657 | $5.9M |
| Baldwin Wealth Partners LLC | 0.38% | No change | 48,570 | $5.9M |
| Sei Investments Co. | 0.01% | Add +9.5% | 48,127 | $5.8M |
"% of holder's portfolio" is AXSM's weight in each manager's 13F, not the share of Axsome Therapeutics Inc. the manager owns.