Aytu BiopharmaAYTU
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 39 institutions reported holding Aytu Biopharma Inc. (AYTU) in their 13F filings, up 6 from Q3 2025. 8 opened new positions and 3 sold out. The largest holders were Nantahala Capital Management, LLC ($2.8M), Stonepine Capital Management, LLC ($2.1M) and AWM Investment Company, Inc. ($1.6M). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Aytu Biopharma Inc.
- CUSIP
- 054754858
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 8 | $403K |
| Exits | 3 | $33K |
All 13F filers, Q3 2025 → Q4 2025: 285,140 shares bought and 104,002 shares sold, net +181,138 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 39 holders
| Nantahala Capital Management, LLC | 0.17% | No change | 1,086,812 | $2.8M |
| Stonepine Capital Management, LLC | 1.67% | Reduce -8.8% | 813,704 | $2.1M |
| AWM Investment Company, Inc. | 0.16% | No change | 619,574 | $1.6M |
| Diadema Partners LP | 0.47% | Add +12.2% | 305,788 | $795K |
| Vanguard Group Inc. | 0.00% | No change | 278,583 | $724K |
| Two Sigma Investments, LP | 0.00% | Add +55.9% | 107,133 | $279K |
| Renaissance Technologies | 0.00% | Reduce -5.8% | 89,623 | $233K |
| Persistent Asset Partners Ltd | 0.10% | Add +27.2% | 79,415 | $206K |
| Geode Capital Management, LLC | 0.00% | Add +4.3% | 74,097 | $193K |
| Two Sigma Advisers, LP | 0.00% | Add +6.8% | 42,500 | $111K |
| Dimensional Fund Advisors LP | 0.00% | Add +14.2% | 35,363 | $92K |
| FNY Investment Advisers, LLC | 0.02% | Add +24207.7% | 31,600 | $82K |
| DRW Securities, LLC | 0.01% | New | 29,368 | $76K |
| XTX Topco Ltd | 0.00% | New | 25,860 | $67K |
| Bellevue Asset Management, LLC | 0.02% | New | 25,013 | $65K |
| BlackRock, Inc. | 0.00% | No change | 22,793 | $59K |
| Perritt Capital Management Inc | 0.09% | New | 20,000 | $52K |
| Rothschild Wealth LLC | 0.01% | New | 20,000 | $52K |
| Northern Trust Corp. | 0.00% | New | 19,169 | $50K |
| Citadel Advisors | 0.00% | New | 15,551 | $40K |
| Daytona Street Capital LLC | 0.02% | — | 10,000 | $26K |
| Acadian Asset Management LLC | 0.00% | No change | 10,237 | $26K |
| MAI Capital Management | 0.00% | No change | 3,575 | $9K |
| UBS Group AG | 0.00% | Reduce -2.7% | 3,049 | $8K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -60.4% | 1,713 | $4K |
| Osaic Holdings, Inc. | 0.00% | Add +1.1% | 460 | $1K |
| Wells Fargo & Company | 0.00% | No change | 127 | $330 |
| Morgan Stanley | 0.00% | Reduce -56.3% | 125 | $325 |
| Bank of America Corp. | 0.00% | Add +14.9% | 85 | $221 |
| CIBC Private Wealth Group LLC | 0.00% | No change | 83 | $216 |
| Group One Trading LLC | 0.00% | No change | 37 | $96 |
| BNP Paribas Financial Markets | 0.00% | No change | 23 | $60 |
| NewEdge Advisors, LLC | 0.00% | No change | 21 | $55 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -82.3% | 11 | $29 |
| Vision Financial Markets LLC | 0.00% | No change | 2 | $6 |
| Jones Financial Companies LLLP | 0.00% | No change | 1 | $3 |
| Citigroup Inc. | 0.00% | No change | 1 | $3 |
| Royal Bank of Canada | 0.00% | New | 25 | $0 |
| Tsfg, LLC | 0.00% | No change | 1 | $0 |
"% of holder's portfolio" is AYTU's weight in each manager's 13F, not the share of Aytu Biopharma Inc. the manager owns.