Biocryst PharmaceuticalsBCRX
13F holders, Q4 2025 (December 31)273holders −13
44new positions
55sold out
10famous investors
$7.80avg. 13F price*
At the end of Q4 2025, 273 institutions reported holding Biocryst Pharmaceuticals Inc. (BCRX) in their 13F filings, down 13 from Q3 2025. 44 opened new positions and 55 sold out. The largest holders were Vanguard Group Inc. ($173.7M), BlackRock, Inc. ($164.9M) and Ra Capital Management, L.P. ($123.5M). 10 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Biocryst Pharmaceuticals Inc.
- CUSIP
- 09058V103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 44 | $246.2M |
| Exits | 55 | $127.9M |
All 13F filers, Q3 2025 → Q4 2025: 52,921,653 shares bought and 39,496,003 shares sold, net +13,425,650 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 273 holders
| Vanguard Group Inc. | 0.00% | Add +2.2% | 22,273,375 | $173.7M |
| BlackRock, Inc. | 0.00% | Reduce -0.5% | 21,137,791 | $164.9M |
| Ra Capital Management, L.P. | 1.27% | New | 15,827,186 | $123.5M |
| Deerfield Management Company, L.P. | 1.64% | Add +17.9% | 14,341,000 | $111.9M |
| State Street Corp. | 0.00% | Add +12.9% | 11,073,211 | $86.4M |
| Kynam Capital Management, LP | 4.76% | Reduce -0.3% | 9,366,526 | $73.1M |
| Janus Henderson Group PLC | 0.03% | Add +7807.2% | 7,404,386 | $57.8M |
| UBS Group AG | 0.01% | Reduce -11.8% | 5,263,914 | $41.1M |
| Geode Capital Management, LLC | 0.00% | Add +0.0% | 5,053,786 | $39.4M |
| Two Sigma Investments, LP | 0.06% | Add +2.2% | 4,515,317 | $35.2M |
| Two Sigma Advisers, LP | 0.06% | Reduce -3.6% | 4,089,112 | $31.9M |
| Royalty Pharma Sub-Manager, LLC | 17.51% | — | 3,846,154 | $30.0M |
| Nuveen, LLC | 0.01% | Reduce -0.1% | 3,612,366 | $28.2M |
| Goldman Sachs Group Inc. | 0.00% | Add +18.5% | 3,212,785 | $25.1M |
| Perceptive Advisors LLC | 0.45% | New | 3,162,529 | $24.7M |
| GW&K Investment Management, LLC | 0.21% | Add +43.8% | 3,160,924 | $24.7M |
| Eversept Partners, LP | 1.31% | Add +117.9% | 2,992,895 | $23.3M |
| Baker Bros. Advisors LP | 0.13% | New | 2,822,727 | $22.0M |
| BNP Paribas Financial Markets | 0.01% | Add +21.4% | 2,542,714 | $19.8M |
| Fisher Asset Management | 0.01% | Reduce -6.3% | 2,467,567 | $19.2M |
| Vestal Point Capital, LP | 0.64% | New | 2,250,000 | $17.6M |
| Qube Research & Technologies Ltd | 0.02% | Reduce -10.2% | 2,164,162 | $16.9M |
| Elmind Capital, LP | 4.95% | — | 2,150,000 | $16.8M |
| Renaissance Technologies | 0.03% | Reduce -0.6% | 2,128,821 | $16.6M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.5% | 2,004,939 | $15.6M |
| Rice Hall James & Associates, LLC | 0.82% | Add +1.3% | 1,904,146 | $14.9M |
| Northern Trust Corp. | 0.00% | Reduce -1.9% | 1,856,903 | $14.5M |
| Stifel Financial Corp. | 0.01% | Add +0.1% | 1,824,517 | $14.2M |
| Morgan Stanley | 0.00% | Reduce -66.5% | 1,745,563 | $13.6M |
| Orbimed Advisors LLC | 0.28% | Add +93.2% | 1,741,800 | $13.6M |
| Squarepoint Ops LLC | 0.03% | Add +49.7% | 1,659,192 | $12.9M |
| Bank of America Corp. | 0.00% | Reduce -19.3% | 1,535,557 | $12.0M |
| Nantahala Capital Management, LLC | 0.63% | New | 1,356,377 | $10.6M |
| Invesco Ltd. | 0.00% | Add +40.8% | 1,354,897 | $10.6M |
| Citadel Advisors | 0.01% | Reduce -4.5% | 1,298,902 | $10.1M |
| D. E. Shaw & Co. | 0.01% | Reduce -27.0% | 1,247,466 | $9.7M |
| Dimensional Fund Advisors LP | 0.00% | New | 1,228,852 | $9.6M |
| Point72 Asset Management | 0.02% | Add +409.5% | 1,213,576 | $9.5M |
| Jupiter Asset Management Ltd. | 0.07% | Reduce -41.8% | 1,197,619 | $9.3M |
| Jacobs Levy Equity Management, Inc. | 0.03% | Add +178.4% | 1,031,488 | $8.0M |
| Hudson Bay Capital Management LP | 0.05% | New | 1,017,374 | $7.9M |
| Aberdeen Group plc | 0.01% | New | 913,593 | $7.1M |
| Jump Financial, LLC | 0.10% | Reduce -1.5% | 910,930 | $7.1M |
| Parkman Healthcare Partners LLC | 0.67% | Reduce -11.1% | 900,057 | $7.0M |
| JPMorgan Chase & Co. | 0.00% | Reduce -25.5% | 843,370 | $6.6M |
| Sphera Funds Management LTD. | 1.37% | New | 837,889 | $6.5M |
| Tang Capital Management LLC | 0.31% | No change | 800,000 | $6.2M |
| Susquehanna Portfolio Strategies, LLC | 0.09% | New | 778,521 | $6.1M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -38.1% | 740,510 | $5.7M |
| Barclays PLC | 0.00% | Reduce -7.1% | 726,367 | $5.7M |
| HRT Financial LP | 0.02% | Add +1137.9% | 716,826 | $5.6M |
| AQR Capital Management | 0.00% | Reduce -29.6% | 704,291 | $5.5M |
| PDT Partners, LLC | 0.35% | No change | 683,416 | $5.3M |
| Susquehanna International Group, LLP | 0.01% | Add +173.3% | 671,693 | $5.2M |
| Jane Street Group, LLC | 0.01% | Reduce -64.9% | 649,357 | $5.1M |
| Voya Investment Management LLC | 0.01% | Add +37.3% | 625,490 | $4.9M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.9% | 607,992 | $4.7M |
| Franklin Resources Inc. | 0.00% | Add +22.5% | 570,189 | $4.4M |
| FMR LLC | 0.00% | Reduce -14.3% | 560,182 | $4.4M |
| Hillsdale Investment Management Inc. | 0.12% | Reduce -0.5% | 559,100 | $4.4M |
| Deutsche Bank AG | 0.00% | Reduce -54.1% | 491,086 | $3.8M |
| Voloridge Investment Management, LLC | 0.01% | Reduce -53.0% | 449,743 | $3.5M |
| DAFNA Capital Management LLC | 0.77% | Add +91.6% | 418,255 | $3.3M |
| Man Group plc | 0.01% | Add +15.1% | 407,850 | $3.2M |
| Swiss National Bank | 0.00% | Add +2.3% | 394,368 | $3.1M |
| Rafferty Asset Management, LLC | 0.01% | Add +3.6% | 382,556 | $3.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -4.0% | 378,853 | $3.0M |
| Principal Financial Group Inc. | 0.00% | Add +54.1% | 376,568 | $2.9M |
| First Trust Advisors LP | 0.00% | Reduce -49.0% | 374,961 | $2.9M |
| Assenagon Asset Management S.A. | 0.00% | Reduce -88.4% | 359,580 | $2.8M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Reduce -57.9% | 357,086 | $2.8M |
| State of Wisconsin Investment Board | 0.01% | Reduce -7.6% | 347,190 | $2.7M |
| Los Angeles Capital Management LLC | 0.01% | Add +14.9% | 355,055 | $2.6M |
| Canada Pension Plan Investment Board | 0.00% | Add +42.4% | 327,941 | $2.6M |
| Victory Capital Management Inc. | 0.00% | Add +446.4% | 325,051 | $2.5M |
| Ishara Investments LP | 2.72% | — | 300,000 | $2.3M |
| Federated Hermes, Inc. | 0.00% | Add +10.3% | 292,850 | $2.3M |
| Alliancebernstein L.P. | 0.00% | Reduce -0.1% | 278,190 | $2.2M |
| Doliver Advisors, LP | 0.54% | No change | 274,328 | $2.1M |
| Rhumbline Advisers | 0.00% | Reduce -18.4% | 266,562 | $2.1M |
| Hussman Strategic Advisors, Inc. | 0.48% | Add +20.0% | 252,000 | $2.0M |
| Walleye Capital LLC | 0.01% | Add +10.8% | 251,670 | $2.0M |
| Phocas Financial Corp. | 0.25% | New | 250,797 | $2.0M |
| Bridgewater Associates | 0.01% | Reduce -42.8% | 235,572 | $1.8M |
| Wells Fargo & Company | 0.00% | Add +75.6% | 233,639 | $1.8M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Add +106.5% | 233,354 | $1.8M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -27.1% | 229,226 | $1.8M |
| Engineers Gate Manager LP | 0.02% | Reduce -49.3% | 224,543 | $1.8M |
| Gotham Asset Management | 0.01% | Reduce -36.9% | 216,946 | $1.7M |
| Legal & General Group Plc | 0.00% | Reduce -6.7% | 210,999 | $1.6M |
| Integral Health Asset Management, LLC | 0.08% | New | 200,000 | $1.6M |
| California State Teachers Retirement System | 0.00% | Add +5.1% | 191,847 | $1.5M |
| Diadema Partners LP | 0.89% | New | 190,928 | $1.5M |
| T. Rowe Price Associates Inc. | 0.00% | Add +9.9% | 177,392 | $1.4M |
| Royal Bank of Canada | 0.00% | Reduce -12.9% | 161,456 | $1.3M |
| Mackenzie Financial Corp. | 0.00% | Add +16.6% | 150,728 | $1.2M |
| Profund Advisors LLC | 0.03% | Add +77.4% | 141,985 | $1.1M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -15.2% | 141,449 | $1.1M |
| OP Asset Management Ltd | 0.01% | New | 139,207 | $1.1M |
| Millennium Management | 0.00% | Reduce -70.1% | 137,626 | $1.1M |
"% of holder's portfolio" is BCRX's weight in each manager's 13F, not the share of Biocryst Pharmaceuticals Inc. the manager owns.