Biocryst PharmaceuticalsBCRX
13F holders, Q4 2025 (December 31)273holders −13
44new positions
55sold out
10famous investors
$7.80avg. 13F price*
At the end of Q4 2025, 273 institutions reported holding Biocryst Pharmaceuticals Inc. (BCRX) in their 13F filings, down 13 from Q3 2025. 44 opened new positions and 55 sold out. The largest holders were Vanguard Group Inc. ($173.7M), BlackRock, Inc. ($164.9M) and Ra Capital Management, L.P. ($123.5M). 10 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Biocryst Pharmaceuticals Inc.
- CUSIP
- 09058V103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 44 | $246.2M |
| Exits | 55 | $127.9M |
All 13F filers, Q3 2025 → Q4 2025: 52,921,653 shares bought and 39,496,003 shares sold, net +13,425,650 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 273 holders
| Vanguard Group Inc. | 0.00% | Add +2.2% | 22,273,375 | $173.7M |
| BlackRock, Inc. | 0.00% | Reduce -0.5% | 21,137,791 | $164.9M |
| Ra Capital Management, L.P. | 1.27% | New | 15,827,186 | $123.5M |
| Deerfield Management Company, L.P. | 1.64% | Add +17.9% | 14,341,000 | $111.9M |
| State Street Corp. | 0.00% | Add +12.9% | 11,073,211 | $86.4M |
| Kynam Capital Management, LP | 4.76% | Reduce -0.3% | 9,366,526 | $73.1M |
| Janus Henderson Group PLC | 0.03% | Add +7807.2% | 7,404,386 | $57.8M |
| UBS Group AG | 0.01% | Reduce -11.8% | 5,263,914 | $41.1M |
| Geode Capital Management, LLC | 0.00% | Add +0.0% | 5,053,786 | $39.4M |
| Two Sigma Investments, LP | 0.06% | Add +2.2% | 4,515,317 | $35.2M |
| Two Sigma Advisers, LP | 0.06% | Reduce -3.6% | 4,089,112 | $31.9M |
| Royalty Pharma Sub-Manager, LLC | 17.51% | — | 3,846,154 | $30.0M |
| Nuveen, LLC | 0.01% | Reduce -0.1% | 3,612,366 | $28.2M |
| Goldman Sachs Group Inc. | 0.00% | Add +18.5% | 3,212,785 | $25.1M |
| Perceptive Advisors LLC | 0.45% | New | 3,162,529 | $24.7M |
| GW&K Investment Management, LLC | 0.21% | Add +43.8% | 3,160,924 | $24.7M |
| Eversept Partners, LP | 1.31% | Add +117.9% | 2,992,895 | $23.3M |
| Baker Bros. Advisors LP | 0.13% | New | 2,822,727 | $22.0M |
| BNP Paribas Financial Markets | 0.01% | Add +21.4% | 2,542,714 | $19.8M |
| Fisher Asset Management | 0.01% | Reduce -6.3% | 2,467,567 | $19.2M |
| Vestal Point Capital, LP | 0.64% | New | 2,250,000 | $17.6M |
| Qube Research & Technologies Ltd | 0.02% | Reduce -10.2% | 2,164,162 | $16.9M |
| Elmind Capital, LP | 4.95% | — | 2,150,000 | $16.8M |
| Renaissance Technologies | 0.03% | Reduce -0.6% | 2,128,821 | $16.6M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.5% | 2,004,939 | $15.6M |
| Rice Hall James & Associates, LLC | 0.82% | Add +1.3% | 1,904,146 | $14.9M |
| Northern Trust Corp. | 0.00% | Reduce -1.9% | 1,856,903 | $14.5M |
| Stifel Financial Corp. | 0.01% | Add +0.1% | 1,824,517 | $14.2M |
| Morgan Stanley | 0.00% | Reduce -66.5% | 1,745,563 | $13.6M |
| Orbimed Advisors LLC | 0.28% | Add +93.2% | 1,741,800 | $13.6M |
| Squarepoint Ops LLC | 0.03% | Add +49.7% | 1,659,192 | $12.9M |
| Bank of America Corp. | 0.00% | Reduce -19.3% | 1,535,557 | $12.0M |
| Nantahala Capital Management, LLC | 0.63% | New | 1,356,377 | $10.6M |
| Invesco Ltd. | 0.00% | Add +40.8% | 1,354,897 | $10.6M |
| Citadel Advisors | 0.01% | Reduce -4.5% | 1,298,902 | $10.1M |
| D. E. Shaw & Co. | 0.01% | Reduce -27.0% | 1,247,466 | $9.7M |
| Dimensional Fund Advisors LP | 0.00% | New | 1,228,852 | $9.6M |
| Point72 Asset Management | 0.02% | Add +409.5% | 1,213,576 | $9.5M |
| Jupiter Asset Management Ltd. | 0.07% | Reduce -41.8% | 1,197,619 | $9.3M |
| Jacobs Levy Equity Management, Inc. | 0.03% | Add +178.4% | 1,031,488 | $8.0M |
| Hudson Bay Capital Management LP | 0.05% | New | 1,017,374 | $7.9M |
| Aberdeen Group plc | 0.01% | New | 913,593 | $7.1M |
| Jump Financial, LLC | 0.10% | Reduce -1.5% | 910,930 | $7.1M |
| Parkman Healthcare Partners LLC | 0.67% | Reduce -11.1% | 900,057 | $7.0M |
| JPMorgan Chase & Co. | 0.00% | Reduce -25.5% | 843,370 | $6.6M |
| Sphera Funds Management LTD. | 1.37% | New | 837,889 | $6.5M |
| Tang Capital Management LLC | 0.31% | No change | 800,000 | $6.2M |
| Susquehanna Portfolio Strategies, LLC | 0.09% | New | 778,521 | $6.1M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -38.1% | 740,510 | $5.7M |
| Barclays PLC | 0.00% | Reduce -7.1% | 726,367 | $5.7M |
| HRT Financial LP | 0.02% | Add +1137.9% | 716,826 | $5.6M |
| AQR Capital Management | 0.00% | Reduce -29.6% | 704,291 | $5.5M |
| PDT Partners, LLC | 0.35% | No change | 683,416 | $5.3M |
| Susquehanna International Group, LLP | 0.01% | Add +173.3% | 671,693 | $5.2M |
| Jane Street Group, LLC | 0.01% | Reduce -64.9% | 649,357 | $5.1M |
| Voya Investment Management LLC | 0.01% | Add +37.3% | 625,490 | $4.9M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.9% | 607,992 | $4.7M |
| Franklin Resources Inc. | 0.00% | Add +22.5% | 570,189 | $4.4M |
| FMR LLC | 0.00% | Reduce -14.3% | 560,182 | $4.4M |
| Hillsdale Investment Management Inc. | 0.12% | Reduce -0.5% | 559,100 | $4.4M |
| Deutsche Bank AG | 0.00% | Reduce -54.1% | 491,086 | $3.8M |
| Voloridge Investment Management, LLC | 0.01% | Reduce -53.0% | 449,743 | $3.5M |
| DAFNA Capital Management LLC | 0.77% | Add +91.6% | 418,255 | $3.3M |
| Man Group plc | 0.01% | Add +15.1% | 407,850 | $3.2M |
| Swiss National Bank | 0.00% | Add +2.3% | 394,368 | $3.1M |
| Rafferty Asset Management, LLC | 0.01% | Add +3.6% | 382,556 | $3.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -4.0% | 378,853 | $3.0M |
| Principal Financial Group Inc. | 0.00% | Add +54.1% | 376,568 | $2.9M |
| First Trust Advisors LP | 0.00% | Reduce -49.0% | 374,961 | $2.9M |
| Assenagon Asset Management S.A. | 0.00% | Reduce -88.4% | 359,580 | $2.8M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Reduce -57.9% | 357,086 | $2.8M |
| State of Wisconsin Investment Board | 0.01% | Reduce -7.6% | 347,190 | $2.7M |
| Los Angeles Capital Management LLC | 0.01% | Add +14.9% | 355,055 | $2.6M |
| Canada Pension Plan Investment Board | 0.00% | Add +42.4% | 327,941 | $2.6M |
| Victory Capital Management Inc. | 0.00% | Add +446.4% | 325,051 | $2.5M |
| Ishara Investments LP | 2.72% | — | 300,000 | $2.3M |
| Federated Hermes, Inc. | 0.00% | Add +10.3% | 292,850 | $2.3M |
| Alliancebernstein L.P. | 0.00% | Reduce -0.1% | 278,190 | $2.2M |
| Doliver Advisors, LP | 0.54% | No change | 274,328 | $2.1M |
| Rhumbline Advisers | 0.00% | Reduce -18.4% | 266,562 | $2.1M |
| Hussman Strategic Advisors, Inc. | 0.48% | Add +20.0% | 252,000 | $2.0M |
| Walleye Capital LLC | 0.01% | Add +10.8% | 251,670 | $2.0M |
| Phocas Financial Corp. | 0.25% | New | 250,797 | $2.0M |
| Bridgewater Associates | 0.01% | Reduce -42.8% | 235,572 | $1.8M |
| Wells Fargo & Company | 0.00% | Add +75.6% | 233,639 | $1.8M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Add +106.5% | 233,354 | $1.8M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -27.1% | 229,226 | $1.8M |
| Engineers Gate Manager LP | 0.02% | Reduce -49.3% | 224,543 | $1.8M |
| Gotham Asset Management | 0.01% | Reduce -36.9% | 216,946 | $1.7M |
| Legal & General Group Plc | 0.00% | Reduce -6.7% | 210,999 | $1.6M |
| Integral Health Asset Management, LLC | 0.08% | New | 200,000 | $1.6M |
| California State Teachers Retirement System | 0.00% | Add +5.1% | 191,847 | $1.5M |
| Diadema Partners LP | 0.89% | New | 190,928 | $1.5M |
| T. Rowe Price Associates Inc. | 0.00% | Add +9.9% | 177,392 | $1.4M |
| Royal Bank of Canada | 0.00% | Reduce -12.9% | 161,456 | $1.3M |
| Mackenzie Financial Corp. | 0.00% | Add +16.6% | 150,728 | $1.2M |
| Profund Advisors LLC | 0.03% | Add +77.4% | 141,985 | $1.1M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -15.2% | 141,449 | $1.1M |
| OP Asset Management Ltd | 0.01% | New | 139,207 | $1.1M |
| Millennium Management | 0.00% | Reduce -70.1% | 137,626 | $1.1M |
| Raymond James Financial Inc. | 0.00% | Add +24.7% | 131,103 | $1.0M |
| QTR Family Wealth, LLC | 0.44% | Reduce -2.0% | 154,062 | $1.0M |
| SG Americas Securities, LLC | 0.00% | Reduce -44.6% | 126,685 | $988K |
| Elo Mutual Pension Insurance Co | 0.01% | Reduce -3.1% | 123,539 | $964K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +2.9% | 119,567 | $929K |
| Headlands Technologies LLC | 0.08% | Add +3.6% | 118,473 | $924K |
| MetLife Investment Management, LLC | 0.00% | Reduce -0.1% | 117,853 | $919K |
| Tudor Investment Corporation | 0.01% | Add +16.7% | 114,541 | $893K |
| Hennion & Walsh Asset Management, Inc. | 0.03% | Add +31.3% | 112,539 | $878K |
| Gsa Capital Partners LLP | 0.07% | Reduce -43.1% | 108,229 | $844K |
| American Century Companies Inc. | 0.00% | Reduce -9.4% | 105,385 | $822K |
| Sei Investments Co. | 0.00% | Reduce -71.5% | 103,157 | $805K |
| New York State Common Retirement Fund | 0.00% | Add +51.9% | 100,690 | $785K |
| Empire Financial Management Company, LLC | 0.17% | New | 100,000 | $780K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -8.1% | 97,634 | $762K |
| Counterweight Ventures, LLC | 0.42% | Add +2.1% | 95,384 | $744K |
| Virtus Investment Advisers, LLC | 0.19% | Add +111.3% | 90,278 | $704K |
| Panagora Asset Management Inc. | 0.00% | Reduce -28.3% | 88,876 | $693K |
| Wellington Management Group LLP | 0.00% | Reduce -7.5% | 86,520 | $675K |
| Acadian Asset Management LLC | 0.00% | Reduce -89.8% | 85,300 | $662K |
| Graham Capital Management, L.P. | 0.03% | Reduce -68.7% | 83,876 | $654K |
| Osaic Holdings, Inc. | 0.00% | Add +34.0% | 82,766 | $646K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -36.7% | 79,747 | $622K |
| Intech Investment Management LLC | 0.01% | Reduce -21.6% | 79,418 | $619K |
| AlphaQuest LLC | 0.03% | Add +19.2% | 76,405 | $596K |
| Jain Global LLC | 0.01% | New | 74,455 | $581K |
| Corient Private Wealth LP | 0.00% | Reduce -0.6% | 70,378 | $549K |
| Lazard Asset Management LLC | 0.00% | Add +30.6% | 69,598 | $543K |
| Campbell & CO Investment Adviser LLC | 0.03% | Reduce -37.4% | 68,559 | $535K |
| Arrowstreet Capital, Limited Partnership | 0.00% | Reduce -98.7% | 66,244 | $517K |
| University of Texas/Texas Am Investment Management Co. | 0.07% | New | 64,507 | $503K |
| Personal Cfo Solutions, LLC | 0.08% | Add +0.3% | 62,400 | $487K |
| Group One Trading LLC | 0.01% | Add +53.1% | 60,524 | $472K |
| Inspire Investing, LLC | 0.04% | Add +0.2% | 60,049 | $468K |
| Sanctuary Advisors, LLC | 0.00% | Add +36.1% | 58,571 | $457K |
| Citigroup Inc. | 0.00% | Add +105.6% | 58,269 | $454K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 58,046 | $453K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 57,351 | $447K |
| Entropy Technologies, LP | 0.02% | Reduce -16.3% | 56,517 | $441K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 56,361 | $440K |
| Arizona State Retirement System | 0.00% | Reduce -4.6% | 56,082 | $437K |
| Envestnet Asset Management Inc. | 0.00% | Add +82.0% | 54,065 | $422K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 73,765 | $413K |
| Voleon Capital Management LP | 0.01% | Reduce -51.3% | 52,345 | $408K |
| State of Wyoming | 0.04% | Add +39.9% | 51,893 | $405K |
| Persistent Asset Partners Ltd | 0.19% | New | 51,701 | $403K |
| NewEdge Advisors, LLC | 0.00% | New | 50,041 | $390K |
| Creative Planning | 0.00% | Reduce -43.7% | 49,780 | $388K |
| ProShare Advisors LLC | 0.00% | Add +9.9% | 47,604 | $371K |
| ADAR1 Capital Management, LLC | 0.03% | New | 45,000 | $351K |
| KLP Kapitalforvaltning As | 0.00% | Add +7.8% | 42,900 | $335K |
| Erste Asset Management GmbH | 0.00% | No change | 40,000 | $308K |
| Commerce Bank | 0.00% | Add +31.5% | 39,065 | $305K |
| Caxton Associates LLP | 0.01% | Add +142.8% | 38,144 | $298K |
| GRIMES & Co WEALTH MANAGEMENT, LLC | 0.01% | Reduce -29.7% | 37,952 | $296K |
| Fiduciary Trust Co | 0.00% | Add +43.2% | 37,253 | $291K |
| China Universal Asset Management Co., Ltd. | 0.02% | Reduce -6.8% | 34,308 | $268K |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 0.00% | Add +34.7% | 32,910 | $257K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Reduce -22.8% | 31,791 | $248K |
| Mariner, LLC | 0.00% | Add +60.0% | 31,495 | $246K |
| Councilor Wealth, LLC | 0.11% | No change | 30,000 | $234K |
| Quarry LP | 0.04% | New | 30,000 | $234K |
| Teacher Retirement System of Texas | 0.00% | Reduce -39.3% | 29,643 | $231K |
| Aigen Investment Management, LP | 0.05% | Reduce -72.0% | 28,058 | $219K |
| Leisure Capital Management | 0.07% | No change | 28,000 | $218K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 27,713 | $216K |
| Vinva Investment Management Ltd | 0.00% | Reduce -64.7% | 18,733 | $214K |
| Rockefeller Capital Management L.P. | 0.00% | Add +403.2% | 26,797 | $209K |
| Janney Montgomery Scott LLC | 0.00% | Reduce -6.3% | 26,133 | $204K |
| Csenge Advisory Group | 0.01% | No change | 25,000 | $195K |
| Abel Hall, LLC | 0.05% | New | 24,898 | $194K |
| LPL Financial LLC | 0.00% | Add +43.9% | 24,480 | $191K |
| HSBC Holdings PLC | 0.00% | Reduce -61.0% | 24,133 | $188K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 24,000 | $187K |
| Legato Capital Management LLC | 0.02% | Add +10.0% | 23,949 | $187K |
| Walleye Trading LLC | 0.00% | New | 23,777 | $185K |
| Twinbeech Capital LP | 0.01% | Reduce -87.9% | 23,700 | $185K |
| Quantinno Capital Management LP | 0.00% | Reduce -21.6% | 23,152 | $181K |
| Xponance LLC | 0.00% | Add +0.4% | 22,258 | $174K |
| Navellier & Associates Inc. | 0.02% | Reduce -67.3% | 21,903 | $171K |
| Visionary Wealth Advisors | 0.01% | No change | 20,090 | $157K |
| Cypress Wealth Services, LLC | 0.02% | No change | 20,000 | $156K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -13.2% | 19,473 | $152K |
| Banco Bilbao Vizcaya Argentaria, S.A. | 0.00% | New | 19,249 | $148K |
| Brooklyn Investment Group | 0.01% | New | 18,708 | $144K |
| HighTower Advisors, LLC | 0.00% | Add +5.4% | 18,030 | $141K |
| Captrust Financial Advisors | 0.00% | Reduce -9.4% | 17,740 | $138K |
| PNC Financial Services Group, Inc. | 0.00% | Add +4.7% | 17,715 | $138K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 17,500 | $137K |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -71.5% | 17,374 | $136K |
| XTX Topco Ltd | 0.00% | New | 17,111 | $133K |
| WINTON GROUP Ltd | 0.00% | New | 15,600 | $122K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Reduce -26.6% | 16,018 | $121K |
| Stratos Wealth Partners, LTD. | 0.00% | New | 14,700 | $115K |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -69.2% | 14,400 | $112K |
| Atria Investments, Inc | 0.00% | Add +15.2% | 14,092 | $110K |
| Cibc World Markets Corp. | 0.00% | — | 13,858 | $108K |
| SteelPeak Wealth, LLC | 0.00% | New | 13,690 | $107K |
| Inceptionr LLC | 0.03% | Add +20.5% | 13,631 | $106K |
| Choreo, LLC | 0.00% | Add +0.1% | 13,764 | $105K |
| Quantessence Capital LLC | 1.19% | New | 13,200 | $103K |
| Kestra Advisory Services, LLC | 0.00% | Reduce -0.6% | 13,060 | $102K |
| Prudential Financial Inc. | 0.00% | Reduce -96.8% | 12,790 | $100K |
| Pinnacle Wealth Planning Services, Inc. | 0.01% | No change | 12,778 | $100K |
| EntryPoint Capital, LLC | 0.04% | Reduce -70.0% | 12,691 | $99K |
| DRW Securities, LLC | 0.01% | Reduce -88.2% | 12,397 | $97K |
| Cetera Investment Advisers | 0.00% | Add +13.8% | 12,330 | $96K |
| Elevation Point Wealth Partners, LLC | 0.00% | Add +13.0% | 12,123 | $95K |
| Vestmark Advisory Solutions, Inc. | 0.00% | Add +13.0% | 12,123 | $95K |
| State of Alaska, Department of Revenue | 0.00% | No change | 11,899 | $92K |
| Farther Finance Advisors, LLC | 0.00% | Add +8.5% | 11,492 | $90K |
| Envestnet Portfolio Solutions, Inc. | 0.00% | New | 10,430 | $81K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +26.1% | 10,231 | $80K |
| Bayforest Capital Ltd | 0.05% | Reduce -87.9% | 8,479 | $66K |
| Cwm, LLC | 0.00% | Reduce -72.0% | 8,361 | $65K |
| Huntington National Bank | 0.00% | Add +13.8% | 7,553 | $59K |
| KBC Group NV | 0.00% | No change | 6,947 | $54K |
| Amalgamated Bank | 0.00% | Reduce -8.0% | 6,581 | $51K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -0.0% | 6,127 | $48K |
| Lanark Financial, Inc. | 0.00% | No change | 6,000 | $47K |
| Signaturefd, LLC | 0.00% | Reduce -3.1% | 5,760 | $45K |
| Assetmark, Inc. | 0.00% | Add +31.6% | 4,768 | $37K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -8.4% | 4,137 | $32K |
| Essential Partners LLC | 0.01% | Reduce -19.8% | 4,046 | $32K |
| Larson Financial Group LLC | 0.00% | Add +1188.0% | 3,542 | $28K |
| Federation des caisses Desjardins du Quebec | 0.00% | Add +26.1% | 3,020 | $24K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -9.4% | 2,557 | $20K |
| Jones Financial Companies LLLP | 0.00% | Add +48.4% | 2,200 | $17K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +30.3% | 2,168 | $17K |
| Activest Wealth Management | 0.00% | No change | 2,000 | $16K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -91.8% | 1,524 | $12K |
| Sterling Capital Management LLC | 0.00% | Add +173.8% | 1,391 | $11K |
| Oakworth Capital, Inc. | 0.00% | Add +7.0% | 1,038 | $8K |
| Westside Investment Management, Inc. | 0.00% | Add +100.0% | 1,000 | $8K |
| Smartleaf Asset Management LLC | 0.00% | Add +1.8% | 955 | $7K |
| Aster Capital Management (DIFC) Ltd | 0.00% | New | 894 | $7K |
| Quadrant Capital Group LLC | 0.00% | No change | 705 | $5K |
| Root Financial Partners, LLC | 0.00% | No change | 700 | $5K |
| Daiwa Securities Group Inc. | 0.00% | No change | 692 | $5K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -47.9% | 564 | $4K |
| Farmers & Merchants Trust Co of Chambersburg PA | 0.00% | No change | 500 | $4K |
| National Bank of Canada | 0.00% | New | 500 | $4K |
| Optiver Holding B.V. | 0.00% | Reduce -62.6% | 483 | $4K |
| Allworth Financial LP | 0.00% | Reduce -20.3% | 432 | $3K |
| Independence Bank of Kentucky | 0.00% | New | 400 | $3K |
| Bradley & Co. Private Wealth Management, LLC | 0.00% | New | 370 | $3K |
| Flagship Harbor Advisors, LLC | 0.00% | New | 325 | $3K |
| Covestor Ltd | 0.00% | Reduce -0.5% | 202 | $2K |
| Bessemer Group Inc. | 0.00% | No change | 278 | $2K |
| GAMMA Investing LLC | 0.00% | Reduce -30.1% | 241 | $2K |
| Brown Brothers Harriman & Co. | 0.00% | No change | 219 | $2K |
| Rothschild Investment LLC | 0.00% | Reduce -33.8% | 202 | $2K |
| Pingora Partners LLC | 0.00% | No change | 200 | $2K |
| Comerica Bank | 0.00% | Add +24.3% | 184 | $1K |
| Private Trust Co. NA | 0.00% | No change | 159 | $1K |
| Versant Capital Management, Inc | 0.00% | No change | 154 | $1K |
| Parkside Financial Bank & Trust | 0.00% | Reduce -26.4% | 148 | $1K |
| IFP Advisors, Inc | 0.00% | Reduce -82.0% | 124 | $967 |
| Torren Management, LLC | 0.00% | — | 111 | $866 |
| Bell Investment Advisors, Inc | 0.00% | No change | 107 | $835 |
| Parallel Advisors, LLC | 0.00% | Reduce -35.0% | 93 | $725 |
| Cornerstone Planning Group LLC | 0.00% | Add +108.3% | 100 | $666 |
| Sound Income Strategies, LLC | 0.00% | New | 100 | $666 |
| Global Retirement Partners, LLC | 0.00% | New | 70 | $546 |
| Harbour Investments, Inc. | 0.00% | No change | 51 | $398 |
| Arax Advisory Partners | 0.00% | Reduce -98.5% | 46 | $359 |
| MAI Capital Management | 0.00% | New | 40 | $312 |
| Chilton Capital Management LLC | 0.00% | New | 40 | $312 |
| SBI Securities Co., Ltd. | 0.00% | Add +25.0% | 35 | $273 |
| SageView Advisory Group, LLC | 0.00% | New | 20 | $156 |
| SJS Investment Consulting Inc. | 0.00% | New | 14 | $110 |
| Clearstead Advisors, LLC | 0.00% | New | 4 | $32 |
| Dunhill Financial, LLC | 0.00% | New | 2 | $18 |
"% of holder's portfolio" is BCRX's weight in each manager's 13F, not the share of Biocryst Pharmaceuticals Inc. the manager owns.