Blueprint MedicinesBPMC
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 353 institutions reported holding Blueprint Medicines Corp. (BPMC) in their 13F filings, up 7 from Q4 2024. 61 opened new positions and 52 sold out. The largest holders were BlackRock, Inc. ($594.0M), Vanguard Group Inc. ($587.8M) and T. Rowe Price Associates Inc. ($479.4M). 6 famous investors held it, including Israel Englander (0.1% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Blueprint Medicines Corp.
- CUSIP
- 09627Y109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 61 | $221.5M |
| Exits | 52 | $121.9M |
All 13F filers, Q4 2024 → Q1 2025: 9,996,684 shares bought and 7,882,214 shares sold, net +2,114,470 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 353 holders
| BlackRock, Inc. | 0.01% | Reduce -2.3% | 6,710,708 | $594.0M |
| Vanguard Group Inc. | 0.01% | Reduce -2.0% | 6,640,523 | $587.8M |
| T. Rowe Price Associates Inc. | 0.06% | Reduce -4.6% | 5,415,837 | $479.4M |
| Avoro Capital Advisors LLC | 5.32% | Add +224.9% | 3,850,000 | $340.8M |
| Wellington Management Group LLP | 0.05% | Reduce -28.2% | 3,073,306 | $272.0M |
| State Street Corp. | 0.01% | Add +7.4% | 2,684,117 | $237.6M |
| JPMorgan Chase & Co. | 0.02% | Add +116.9% | 2,506,514 | $221.9M |
| Geode Capital Management, LLC | 0.01% | Add +2.2% | 1,522,647 | $134.8M |
| FMR LLC | 0.01% | Reduce -36.2% | 1,433,169 | $126.8M |
| William Blair Investment Management, LLC | 0.36% | Reduce -26.5% | 1,429,668 | $126.5M |
| T. Rowe Price Investment Management, Inc. | 0.08% | Add +86.9% | 1,302,810 | $115.3M |
| Macquarie Group Ltd. | 0.14% | Add +2.2% | 1,286,897 | $113.9M |
| Alliancebernstein L.P. | 0.04% | Add +5.1% | 1,196,240 | $105.9M |
| Rock Springs Capital Management LP | 5.12% | Reduce -8.1% | 1,007,569 | $89.2M |
| Invesco Ltd. | 0.02% | Add +2.5% | 984,674 | $87.2M |
| Pictet Asset Management Holding SA | 0.09% | Reduce -19.4% | 954,596 | $84.5M |
| Goldman Sachs Group Inc. | 0.02% | Reduce -11.4% | 926,668 | $82.0M |
| Alkeon Capital Management LLC | 0.47% | Add +12.5% | 900,628 | $79.7M |
| Hood River Capital Management LLC | 1.36% | Add +2.3% | 900,205 | $79.7M |
| American Century Companies Inc. | 0.05% | Add +3.3% | 866,763 | $76.7M |
| Eventide Asset Management, LLC | 1.52% | Add +0.0% | 862,549 | $76.3M |
| Siren, L.L.C. | 3.63% | New | 726,167 | $64.3M |
| Bank of America Corp. | 0.01% | Add +81.5% | 716,906 | $63.5M |
| Millennium Management | 0.06% | Reduce -6.2% | 691,395 | $61.2M |
| Clearbridge Investments, LLC | 0.05% | Add +36.9% | 671,617 | $59.4M |
| Norges Bank | 0.01% | Reduce -15.2% | 602,927 | $53.4M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -0.8% | 599,721 | $53.1M |
| Northern Trust Corp. | 0.01% | Reduce -3.1% | 589,559 | $52.2M |
| Brown Advisory Inc. | 0.07% | Add +0.5% | 581,864 | $51.5M |
| Jacobs Levy Equity Management, Inc. | 0.20% | Reduce -12.1% | 570,402 | $50.5M |
| Morgan Stanley | 0.00% | Add +12.8% | 568,699 | $50.3M |
| Polar Capital Holdings Plc | 0.29% | Reduce -13.6% | 541,379 | $47.9M |
| Woodline Partners LP | 0.31% | Add +0.1% | 540,738 | $47.9M |
| Man Group plc | 0.14% | Add +400.1% | 519,737 | $46.0M |
| Braidwell LP | 2.03% | New | 439,968 | $38.9M |
| Susquehanna International Group, LLP | 0.06% | Add +202.9% | 412,540 | $36.5M |
| Emerald Advisers, LLC | 1.60% | Reduce -3.6% | 401,644 | $35.5M |
| D. E. Shaw & Co. | 0.04% | Add +7.5% | 388,986 | $34.4M |
| Jane Street Group, LLC | 0.06% | Reduce -7.9% | 375,818 | $33.3M |
| Ameriprise Financial Inc. | 0.01% | Add +6.9% | 361,508 | $32.0M |
| Jennison Associates LLC | 0.02% | Reduce -3.2% | 348,817 | $30.9M |
| Qube Research & Technologies Ltd | 0.05% | Reduce -3.7% | 337,151 | $29.8M |
| Casdin Capital, LLC | 2.36% | No change | 326,378 | $28.9M |
| Capital Research Global Investors | 0.01% | New | 311,137 | $27.5M |
| Fisher Asset Management | 0.01% | Reduce -3.8% | 310,734 | $27.5M |
| Bank of New York Mellon Corp | 0.01% | Add +1.2% | 307,018 | $27.2M |
| Citigroup Inc. | 0.02% | Add +220.3% | 304,838 | $27.0M |
| Ensign Peak Advisors, Inc | 0.05% | Add +10.3% | 303,732 | $26.9M |
| Lord, Abbett & Co. LLC | 0.10% | Reduce -13.9% | 288,472 | $25.5M |
| TD Asset Management Inc | 0.02% | Reduce -6.3% | 284,372 | $25.2M |
| Massachusetts Financial Services Co. | 0.01% | Add +0.4% | 270,996 | $24.0M |
| Nuveen, LLC | 0.01% | — | 267,660 | $23.4M |
| Sofinnova Investments, Inc. | 1.74% | New | 261,039 | $23.1M |
| Emerald Mutual Fund Advisers Trust | 1.62% | Reduce -7.0% | 250,158 | $22.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +1.9% | 244,411 | $21.6M |
| Driehaus Capital Management LLC | 0.21% | New | 242,938 | $21.5M |
| Voya Investment Management LLC | 0.03% | Add +17.7% | 241,672 | $21.4M |
| Novo Holdings A/S | 1.54% | Add +30.8% | 228,804 | $20.3M |
| UBS Group AG | 0.00% | Add +8.3% | 213,805 | $18.9M |
| Panagora Asset Management Inc. | 0.09% | Add +187.9% | 205,582 | $18.2M |
| Deutsche Bank AG | 0.01% | Reduce -23.5% | 199,937 | $17.7M |
| Raymond James Financial Inc. | 0.01% | Reduce -19.9% | 193,812 | $17.2M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.07% | Add +28.9% | 183,947 | $16.3M |
| Russell Investments Group, Ltd. | 0.02% | Add +34.3% | 169,115 | $15.0M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -7.0% | 164,055 | $14.5M |
| DAFNA Capital Management LLC | 3.87% | Add +1.7% | 152,263 | $13.5M |
| AQR Capital Management | 0.01% | Add +2.5% | 148,271 | $13.1M |
| Integral Health Asset Management, LLC | 1.42% | Reduce -47.3% | 145,000 | $12.8M |
| Granahan Investment Management, LLC | 0.64% | Add +2.0% | 144,756 | $12.8M |
| Franklin Resources Inc. | 0.00% | Add +272.0% | 136,111 | $12.0M |
| Segall Bryant & Hamill, LLC | 0.18% | Reduce -2.7% | 135,909 | $12.0M |
| Barclays PLC | 0.01% | Reduce -31.5% | 129,595 | $11.5M |
| Swiss National Bank | 0.01% | Reduce -1.2% | 123,100 | $10.9M |
| Ikarian Capital, LLC | 3.28% | Reduce -32.8% | 113,904 | $10.1M |
| Orion Investment Co | 3.95% | Add +0.3% | 109,033 | $9.7M |
| Rafferty Asset Management, LLC | 0.04% | Add +11.7% | 99,320 | $8.8M |
| Peregrine Capital Management LLC | 0.28% | Reduce -2.7% | 96,149 | $8.5M |
| Legal & General Group Plc | 0.00% | Add +1.2% | 95,666 | $8.5M |
| Prudential Financial Inc. | 0.01% | Reduce -7.0% | 93,468 | $8.3M |
| First Turn Management, LLC | 1.64% | Add +37.1% | 92,033 | $8.1M |
| Rhumbline Advisers | 0.01% | Add +6.2% | 91,933 | $8.1M |
| Capital Fund Management S.A. | 0.10% | Add +1.8% | 91,492 | $8.1M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | New | 84,780 | $7.5M |
| Aquilo Capital Management, LLC | 20.03% | Reduce -35.2% | 83,926 | $7.4M |
| BIT Capital GmbH | 0.83% | Reduce -1.4% | 77,802 | $6.9M |
| California Public Employees Retirement System | 0.00% | Reduce -1.1% | 77,556 | $6.9M |
| Assenagon Asset Management S.A. | 0.01% | Reduce -21.7% | 76,270 | $6.8M |
| Oberweis Asset Management Inc./ | 0.33% | No change | 75,000 | $6.6M |
| Aquatic Capital Management LLC | 0.17% | Add +56.7% | 74,574 | $6.6M |
| Ally Bridge Group (NY) LLC | 5.92% | Add +32.7% | 74,192 | $6.6M |
| EFG Asset Management (North America) Corp. | 1.08% | Reduce -1.2% | 73,388 | $6.5M |
| Sei Investments Co. | 0.01% | Add +0.1% | 70,463 | $6.2M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.02% | No change | 69,887 | $6.2M |
| Avidity Partners Management LP | 1.25% | Reduce -61.2% | 68,500 | $6.1M |
| Algert Global LLC | 0.15% | Reduce -39.0% | 68,420 | $6.1M |
| Neuberger Berman Group LLC | 0.01% | Add +2.1% | 67,794 | $6.0M |
| State of Wisconsin Investment Board | 0.01% | Add +52.3% | 64,066 | $5.7M |
| Stempoint Capital LP | 1.75% | New | 61,927 | $5.5M |
| Balyasny Asset Management L.P. | 0.01% | Reduce -41.2% | 60,282 | $5.3M |
| California State Teachers Retirement System | 0.01% | Reduce -1.1% | 58,588 | $5.2M |
"% of holder's portfolio" is BPMC's weight in each manager's 13F, not the share of Blueprint Medicines Corp. the manager owns.