Blueprint MedicinesBPMC

13F holders, Q1 2025 (March 31)
353holders +7
61new positions
52sold out
6famous investors
$88.51avg. 13F price*

At the end of Q1 2025, 353 institutions reported holding Blueprint Medicines Corp. (BPMC) in their 13F filings, up 7 from Q4 2024. 61 opened new positions and 52 sold out. The largest holders were BlackRock, Inc. ($594.0M), Vanguard Group Inc. ($587.8M) and T. Rowe Price Associates Inc. ($479.4M). 6 famous investors held it, including Israel Englander (0.1% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).

Company
Blueprint Medicines Corp.
CUSIP
09627Y109
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400 Q1 2024: 281Q1 2024Q2 2024: 305Q2 2024Q3 2024: 319Q3 2024Q4 2024: 346Q4 2024Q1 2025: 353Q1 2025Q2 2025: 356Q2 2025Q3 2025: 5Q3 2025Q4 2025: 2Q4 2025Q1 2026: 2Q1 2026Q2 2026: 1Q2 2026

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions61$221.5M
Exits52$121.9M

All 13F filers, Q4 2024 → Q1 2025: 9,996,684 shares bought and 7,882,214 shares sold, net +2,114,470 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 353 holders

BlackRock, Inc. 0.01% Reduce -2.3% 6,710,708 $594.0M
Vanguard Group Inc. 0.01% Reduce -2.0% 6,640,523 $587.8M
T. Rowe Price Associates Inc. 0.06% Reduce -4.6% 5,415,837 $479.4M
Avoro Capital Advisors LLC 5.32% Add +224.9% 3,850,000 $340.8M
Wellington Management Group LLP 0.05% Reduce -28.2% 3,073,306 $272.0M
State Street Corp. 0.01% Add +7.4% 2,684,117 $237.6M
JPMorgan Chase & Co. 0.02% Add +116.9% 2,506,514 $221.9M
Geode Capital Management, LLC 0.01% Add +2.2% 1,522,647 $134.8M
FMR LLC 0.01% Reduce -36.2% 1,433,169 $126.8M
William Blair Investment Management, LLC 0.36% Reduce -26.5% 1,429,668 $126.5M
T. Rowe Price Investment Management, Inc. 0.08% Add +86.9% 1,302,810 $115.3M
Macquarie Group Ltd. 0.14% Add +2.2% 1,286,897 $113.9M
Alliancebernstein L.P. 0.04% Add +5.1% 1,196,240 $105.9M
Rock Springs Capital Management LP 5.12% Reduce -8.1% 1,007,569 $89.2M
Invesco Ltd. 0.02% Add +2.5% 984,674 $87.2M
Pictet Asset Management Holding SA 0.09% Reduce -19.4% 954,596 $84.5M
Goldman Sachs Group Inc. 0.02% Reduce -11.4% 926,668 $82.0M
Alkeon Capital Management LLC 0.47% Add +12.5% 900,628 $79.7M
Hood River Capital Management LLC 1.36% Add +2.3% 900,205 $79.7M
American Century Companies Inc. 0.05% Add +3.3% 866,763 $76.7M
Eventide Asset Management, LLC 1.52% Add +0.0% 862,549 $76.3M
Siren, L.L.C. 3.63% New 726,167 $64.3M
Bank of America Corp. 0.01% Add +81.5% 716,906 $63.5M
Millennium Management 0.06% Reduce -6.2% 691,395 $61.2M
Clearbridge Investments, LLC 0.05% Add +36.9% 671,617 $59.4M
Norges Bank 0.01% Reduce -15.2% 602,927 $53.4M
Charles Schwab Investment Management Inc. 0.01% Reduce -0.8% 599,721 $53.1M
Northern Trust Corp. 0.01% Reduce -3.1% 589,559 $52.2M
Brown Advisory Inc. 0.07% Add +0.5% 581,864 $51.5M
Jacobs Levy Equity Management, Inc. 0.20% Reduce -12.1% 570,402 $50.5M
Morgan Stanley 0.00% Add +12.8% 568,699 $50.3M
Polar Capital Holdings Plc 0.29% Reduce -13.6% 541,379 $47.9M
Woodline Partners LP 0.31% Add +0.1% 540,738 $47.9M
Man Group plc 0.14% Add +400.1% 519,737 $46.0M
Braidwell LP 2.03% New 439,968 $38.9M
Susquehanna International Group, LLP 0.06% Add +202.9% 412,540 $36.5M
Emerald Advisers, LLC 1.60% Reduce -3.6% 401,644 $35.5M
D. E. Shaw & Co. 0.04% Add +7.5% 388,986 $34.4M
Jane Street Group, LLC 0.06% Reduce -7.9% 375,818 $33.3M
Ameriprise Financial Inc. 0.01% Add +6.9% 361,508 $32.0M
Jennison Associates LLC 0.02% Reduce -3.2% 348,817 $30.9M
Qube Research & Technologies Ltd 0.05% Reduce -3.7% 337,151 $29.8M
Casdin Capital, LLC 2.36% No change 326,378 $28.9M
Capital Research Global Investors 0.01% New 311,137 $27.5M
Fisher Asset Management 0.01% Reduce -3.8% 310,734 $27.5M
Bank of New York Mellon Corp 0.01% Add +1.2% 307,018 $27.2M
Citigroup Inc. 0.02% Add +220.3% 304,838 $27.0M
Ensign Peak Advisors, Inc 0.05% Add +10.3% 303,732 $26.9M
Lord, Abbett & Co. LLC 0.10% Reduce -13.9% 288,472 $25.5M
TD Asset Management Inc 0.02% Reduce -6.3% 284,372 $25.2M
Massachusetts Financial Services Co. 0.01% Add +0.4% 270,996 $24.0M
Nuveen, LLC 0.01% — 267,660 $23.4M
Sofinnova Investments, Inc. 1.74% New 261,039 $23.1M
Emerald Mutual Fund Advisers Trust 1.62% Reduce -7.0% 250,158 $22.1M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% Add +1.9% 244,411 $21.6M
Driehaus Capital Management LLC 0.21% New 242,938 $21.5M
Voya Investment Management LLC 0.03% Add +17.7% 241,672 $21.4M
Novo Holdings A/S 1.54% Add +30.8% 228,804 $20.3M
UBS Group AG 0.00% Add +8.3% 213,805 $18.9M
Panagora Asset Management Inc. 0.09% Add +187.9% 205,582 $18.2M
Deutsche Bank AG 0.01% Reduce -23.5% 199,937 $17.7M
Raymond James Financial Inc. 0.01% Reduce -19.9% 193,812 $17.2M
Connor, Clark & Lunn Investment Management Ltd. 0.07% Add +28.9% 183,947 $16.3M
Russell Investments Group, Ltd. 0.02% Add +34.3% 169,115 $15.0M
Manufacturers Life Insurance Company, The 0.01% Reduce -7.0% 164,055 $14.5M
DAFNA Capital Management LLC 3.87% Add +1.7% 152,263 $13.5M
AQR Capital Management 0.01% Add +2.5% 148,271 $13.1M
Integral Health Asset Management, LLC 1.42% Reduce -47.3% 145,000 $12.8M
Granahan Investment Management, LLC 0.64% Add +2.0% 144,756 $12.8M
Franklin Resources Inc. 0.00% Add +272.0% 136,111 $12.0M
Segall Bryant & Hamill, LLC 0.18% Reduce -2.7% 135,909 $12.0M
Barclays PLC 0.01% Reduce -31.5% 129,595 $11.5M
Swiss National Bank 0.01% Reduce -1.2% 123,100 $10.9M
Ikarian Capital, LLC 3.28% Reduce -32.8% 113,904 $10.1M
Orion Investment Co 3.95% Add +0.3% 109,033 $9.7M
Rafferty Asset Management, LLC 0.04% Add +11.7% 99,320 $8.8M
Peregrine Capital Management LLC 0.28% Reduce -2.7% 96,149 $8.5M
Legal & General Group Plc 0.00% Add +1.2% 95,666 $8.5M
Prudential Financial Inc. 0.01% Reduce -7.0% 93,468 $8.3M
First Turn Management, LLC 1.64% Add +37.1% 92,033 $8.1M
Rhumbline Advisers 0.01% Add +6.2% 91,933 $8.1M
Capital Fund Management S.A. 0.10% Add +1.8% 91,492 $8.1M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.02% New 84,780 $7.5M
Aquilo Capital Management, LLC 20.03% Reduce -35.2% 83,926 $7.4M
BIT Capital GmbH 0.83% Reduce -1.4% 77,802 $6.9M
California Public Employees Retirement System 0.00% Reduce -1.1% 77,556 $6.9M
Assenagon Asset Management S.A. 0.01% Reduce -21.7% 76,270 $6.8M
Oberweis Asset Management Inc./ 0.33% No change 75,000 $6.6M
Aquatic Capital Management LLC 0.17% Add +56.7% 74,574 $6.6M
Ally Bridge Group (NY) LLC 5.92% Add +32.7% 74,192 $6.6M
EFG Asset Management (North America) Corp. 1.08% Reduce -1.2% 73,388 $6.5M
Sei Investments Co. 0.01% Add +0.1% 70,463 $6.2M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.02% No change 69,887 $6.2M
Avidity Partners Management LP 1.25% Reduce -61.2% 68,500 $6.1M
Algert Global LLC 0.15% Reduce -39.0% 68,420 $6.1M
Neuberger Berman Group LLC 0.01% Add +2.1% 67,794 $6.0M
State of Wisconsin Investment Board 0.01% Add +52.3% 64,066 $5.7M
Stempoint Capital LP 1.75% New 61,927 $5.5M
Balyasny Asset Management L.P. 0.01% Reduce -41.2% 60,282 $5.3M
California State Teachers Retirement System 0.01% Reduce -1.1% 58,588 $5.2M

"% of holder's portfolio" is BPMC's weight in each manager's 13F, not the share of Blueprint Medicines Corp. the manager owns.

Show all 353 holders