Blueprint MedicinesBPMC
13F holders, Q2 2025 (June 30)356holders +3
108new positions
105sold out
8famous investors
$128.18avg. 13F price*
At the end of Q2 2025, 356 institutions reported holding Blueprint Medicines Corp. (BPMC) in their 13F filings, up 3 from Q1 2025. 108 opened new positions and 105 sold out. The largest holders were Vanguard Group Inc. ($822.5M), BlackRock, Inc. ($784.3M) and Pentwater Capital Management LP ($499.9M). 8 famous investors held it, including George Soros (0.9% of Soros Fund Management's portfolio), Paul Tudor Jones (0.5% of Tudor Investment Corporation's portfolio) and Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio).
- Company
- Blueprint Medicines Corp.
- CUSIP
- 09627Y109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 108 | $3.0B |
| Exits | 105 | $917.8M |
All 13F filers, Q1 2025 → Q2 2025: 33,084,151 shares bought and 34,606,826 shares sold, net −1,522,675 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 356 holders
| Vanguard Group Inc. | 0.01% | Reduce -3.4% | 6,416,603 | $822.5M |
| BlackRock, Inc. | 0.01% | Reduce -8.8% | 6,118,428 | $784.3M |
| Pentwater Capital Management LP | 6.39% | New | 3,900,000 | $499.9M |
| HBK Investments L P | 8.28% | New | 3,200,924 | $410.3M |
| State Street Corp. | 0.01% | Reduce -16.9% | 2,230,980 | $286.0M |
| UBS Group AG | 0.06% | Add +913.5% | 2,167,028 | $277.8M |
| FIL Ltd | 0.19% | New | 1,759,500 | $225.5M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 6.28% | Add +11427.7% | 1,713,587 | $219.6M |
| Barclays PLC | 0.08% | Add +1101.4% | 1,556,918 | $199.6M |
| Geode Capital Management, LLC | 0.01% | Add +1.2% | 1,541,013 | $197.6M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -73.0% | 1,464,968 | $187.8M |
| Glazer Capital, LLC | 7.08% | New | 1,331,300 | $170.6M |
| Norges Bank | 0.02% | Add +78.3% | 1,074,936 | $137.8M |
| Beryl Capital Management LLC | 20.60% | New | 1,067,224 | $136.8M |
| Alpine Associates Management Inc. | 7.29% | New | 1,060,307 | $135.9M |
| Davidson Kempner Capital Management LP | 3.14% | New | 1,035,100 | $132.7M |
| Morgan Stanley | 0.01% | Add +81.3% | 1,031,170 | $132.2M |
| Macquarie Group Ltd. | 0.15% | Reduce -28.3% | 922,167 | $118.2M |
| Goldman Sachs Group Inc. | 0.02% | Reduce -3.8% | 891,287 | $114.2M |
| Syquant Capital Sas | 34.46% | New | 805,603 | $103.3M |
| Alliancebernstein L.P. | 0.03% | Reduce -36.0% | 765,387 | $98.1M |
| Magnetar Financial LLC | 0.47% | Add +15881.8% | 730,047 | $93.6M |
| Eventide Asset Management, LLC | 1.64% | Reduce -15.5% | 728,821 | $93.4M |
| Renaissance Technologies | 0.12% | New | 674,500 | $86.5M |
| Bank of America Corp. | 0.01% | Reduce -9.7% | 647,487 | $83.0M |
| Northern Trust Corp. | 0.01% | Reduce -3.5% | 568,924 | $72.9M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -6.4% | 561,159 | $71.9M |
| FMR LLC | 0.00% | Reduce -61.0% | 558,960 | $71.6M |
| Voloridge Investment Management, LLC | 0.26% | Add +5413.3% | 558,768 | $71.6M |
| Woodline Partners LP | 0.36% | Reduce -1.6% | 531,880 | $68.2M |
| Man Group plc | 0.15% | Reduce -0.7% | 516,258 | $66.2M |
| Invesco Ltd. | 0.01% | Reduce -48.1% | 511,091 | $65.5M |
| Balyasny Asset Management L.P. | 0.15% | Add +739.3% | 505,957 | $64.9M |
| Nuveen, LLC | 0.02% | Add +82.5% | 488,612 | $62.6M |
| Nexpoint Asset Management, L.P. | 5.87% | New | 476,742 | $61.1M |
| Tudor Investment Corporation | 0.45% | Add +2029.0% | 468,623 | $60.1M |
| Brown Advisory Inc. | 0.08% | Reduce -21.2% | 458,559 | $58.8M |
| First Trust Capital Management L.P. | 3.95% | New | 456,068 | $58.5M |
| Wellington Management Group LLP | 0.01% | Reduce -85.8% | 435,976 | $55.9M |
| JPMorgan Chase & Co. | 0.00% | Reduce -83.3% | 418,060 | $53.6M |
| Clearbridge Investments, LLC | 0.04% | Reduce -39.6% | 405,708 | $52.0M |
| LMR Partners LLP | 1.16% | Add +3603.4% | 395,857 | $50.7M |
| Quadrature Capital Ltd | 0.85% | New | 382,677 | $49.1M |
| Avoro Capital Advisors LLC | 0.84% | Reduce -90.3% | 375,000 | $48.1M |
| Readystate Asset Management LP | 3.18% | New | 329,831 | $42.3M |
| Whitebox Advisors LLC | 2.86% | New | 310,001 | $39.7M |
| TIG Advisors, LLC | 2.13% | New | 305,097 | $39.1M |
| Millennium Management | 0.04% | Reduce -57.2% | 295,879 | $37.9M |
| Slotnik Capital, LLC | 15.11% | New | 292,694 | $37.5M |
| Bellevue Group AG | 0.80% | New | 284,900 | $36.5M |
| Janus Henderson Group PLC | 0.02% | Add +835.4% | 268,928 | $34.5M |
| Cinctive Capital Management LP | 1.90% | Add +749.5% | 265,000 | $34.0M |
| Novo Holdings A/S | 2.40% | Add +15.8% | 264,956 | $34.0M |
| Polar Asset Management Partners Inc. | 1.13% | New | 262,964 | $33.7M |
| Affinity Asset Advisors, LLC | 4.94% | New | 250,000 | $32.0M |
| Soros Fund Management | 0.85% | New | 250,000 | $32.0M |
| KRYGER CAPITAL Ltd | 5.89% | New | 248,219 | $31.8M |
| Trium Capital LLP | 7.66% | New | 240,099 | $30.8M |
| Bank of New York Mellon Corp | 0.01% | Reduce -25.8% | 227,843 | $29.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Reduce -11.7% | 215,946 | $27.7M |
| Jane Street Group, LLC | 0.04% | Reduce -43.0% | 214,394 | $27.5M |
| Gabelli Funds LLC | 0.20% | New | 211,169 | $27.1M |
| Sand Grove Capital Management LLP | 13.62% | New | 211,124 | $27.1M |
| Highbridge Capital Management LLC | 3.79% | New | 189,822 | $24.3M |
| Deutsche Bank AG | 0.01% | Reduce -5.3% | 189,250 | $24.3M |
| Rock Springs Capital Management LP | 1.49% | Reduce -81.6% | 185,500 | $23.8M |
| Oddo BHF Asset Management Sas | 0.90% | New | 185,000 | $23.7M |
| Susquehanna International Group, LLP | 0.04% | Reduce -55.4% | 184,115 | $23.6M |
| GABELLI & Co INVESTMENT ADVISERS, INC. | 3.62% | New | 183,374 | $23.5M |
| Franklin Resources Inc. | 0.01% | Add +27.5% | 173,510 | $22.2M |
| Picton Mahoney Asset Management | 0.31% | Add +78241.0% | 170,000 | $21.8M |
| DAFNA Capital Management LLC | 6.06% | Add +10.8% | 168,763 | $21.6M |
| Nearwater Capital Markets, Ltd | 0.33% | New | 160,000 | $20.5M |
| Capula Management Ltd | 0.25% | New | 156,114 | $20.0M |
| Citigroup Inc. | 0.01% | Reduce -49.5% | 154,048 | $19.7M |
| Panagora Asset Management Inc. | 0.09% | Reduce -27.3% | 149,440 | $19.2M |
| Jump Financial, LLC | 0.24% | New | 147,325 | $18.9M |
| Susquehanna Portfolio Strategies, LLC | 0.38% | New | 135,057 | $17.3M |
| Squarepoint Ops LLC | 0.04% | Add +418.1% | 130,066 | $16.7M |
| Hudson Bay Capital Management LP | 0.12% | New | 129,398 | $16.6M |
| Baker Bros. Advisors LP | 0.16% | New | 125,538 | $16.1M |
| Swiss National Bank | 0.01% | Reduce -0.9% | 122,000 | $15.6M |
| Credit Industriel Et Commercial | 3.33% | New | 120,850 | $15.5M |
| Twin Securities, Inc. | 13.63% | New | 120,126 | $15.4M |
| Pictet Asset Management Holding SA | 0.02% | Reduce -87.5% | 119,817 | $15.4M |
| Verition Fund Management LLC | 0.09% | Add +591.3% | 118,988 | $15.3M |
| Water Island Capital LLC | 2.89% | New | 116,631 | $14.9M |
| Melqart Asset Management (UK) Ltd | 2.00% | New | 109,437 | $14.0M |
| Orion Investment Co | 4.82% | Reduce -2.7% | 106,134 | $13.6M |
| Voya Investment Management LLC | 0.02% | Reduce -57.6% | 102,552 | $13.1M |
| Rhumbline Advisers | 0.01% | Add +8.4% | 99,649 | $12.8M |
| Legal & General Group Plc | 0.00% | Add +3.7% | 99,224 | $12.7M |
| Harvest Management LLC | 5.91% | New | 95,000 | $12.2M |
| Groupe la Francaise | 0.20% | New | 94,150 | $12.1M |
| Equitec Proprietary Markets, LLC | 47.98% | New | 92,500 | $11.9M |
| AQR Capital Management | 0.01% | Reduce -37.6% | 92,469 | $11.9M |
| State of Wisconsin Investment Board | 0.03% | Add +39.5% | 89,373 | $11.5M |
| Versor Investments LP | 1.99% | New | 88,042 | $11.3M |
| California Public Employees Retirement System | 0.01% | Add +11.8% | 86,709 | $11.1M |
| Prudential Financial Inc. | 0.01% | Reduce -10.2% | 83,973 | $10.8M |
"% of holder's portfolio" is BPMC's weight in each manager's 13F, not the share of Blueprint Medicines Corp. the manager owns.