Blueprint MedicinesBPMC

13F holders, Q1 2025 (March 31)
353holders +7
61new positions
52sold out
6famous investors
$88.51avg. 13F price*

At the end of Q1 2025, 353 institutions reported holding Blueprint Medicines Corp. (BPMC) in their 13F filings, up 7 from Q4 2024. 61 opened new positions and 52 sold out. The largest holders were BlackRock, Inc. ($594.0M), Vanguard Group Inc. ($587.8M) and T. Rowe Price Associates Inc. ($479.4M). 6 famous investors held it, including Israel Englander (0.1% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).

Company
Blueprint Medicines Corp.
CUSIP
09627Y109
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400 Q1 2024: 281Q1 2024Q2 2024: 305Q2 2024Q3 2024: 319Q3 2024Q4 2024: 346Q4 2024Q1 2025: 353Q1 2025Q2 2025: 356Q2 2025Q3 2025: 5Q3 2025Q4 2025: 2Q4 2025Q1 2026: 2Q1 2026Q2 2026: 1Q2 2026

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions61$221.5M
Exits52$121.9M

All 13F filers, Q4 2024 → Q1 2025: 9,996,684 shares bought and 7,882,214 shares sold, net +2,114,470 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 353 holders

BlackRock, Inc. 0.01% Reduce -2.3% 6,710,708 $594.0M
Vanguard Group Inc. 0.01% Reduce -2.0% 6,640,523 $587.8M
T. Rowe Price Associates Inc. 0.06% Reduce -4.6% 5,415,837 $479.4M
Avoro Capital Advisors LLC 5.32% Add +224.9% 3,850,000 $340.8M
Wellington Management Group LLP 0.05% Reduce -28.2% 3,073,306 $272.0M
State Street Corp. 0.01% Add +7.4% 2,684,117 $237.6M
JPMorgan Chase & Co. 0.02% Add +116.9% 2,506,514 $221.9M
Geode Capital Management, LLC 0.01% Add +2.2% 1,522,647 $134.8M
FMR LLC 0.01% Reduce -36.2% 1,433,169 $126.8M
William Blair Investment Management, LLC 0.36% Reduce -26.5% 1,429,668 $126.5M
T. Rowe Price Investment Management, Inc. 0.08% Add +86.9% 1,302,810 $115.3M
Macquarie Group Ltd. 0.14% Add +2.2% 1,286,897 $113.9M
Alliancebernstein L.P. 0.04% Add +5.1% 1,196,240 $105.9M
Rock Springs Capital Management LP 5.12% Reduce -8.1% 1,007,569 $89.2M
Invesco Ltd. 0.02% Add +2.5% 984,674 $87.2M
Pictet Asset Management Holding SA 0.09% Reduce -19.4% 954,596 $84.5M
Goldman Sachs Group Inc. 0.02% Reduce -11.4% 926,668 $82.0M
Alkeon Capital Management LLC 0.47% Add +12.5% 900,628 $79.7M
Hood River Capital Management LLC 1.36% Add +2.3% 900,205 $79.7M
American Century Companies Inc. 0.05% Add +3.3% 866,763 $76.7M
Eventide Asset Management, LLC 1.52% Add +0.0% 862,549 $76.3M
Siren, L.L.C. 3.63% New 726,167 $64.3M
Bank of America Corp. 0.01% Add +81.5% 716,906 $63.5M
Millennium Management 0.06% Reduce -6.2% 691,395 $61.2M
Clearbridge Investments, LLC 0.05% Add +36.9% 671,617 $59.4M
Norges Bank 0.01% Reduce -15.2% 602,927 $53.4M
Charles Schwab Investment Management Inc. 0.01% Reduce -0.8% 599,721 $53.1M
Northern Trust Corp. 0.01% Reduce -3.1% 589,559 $52.2M
Brown Advisory Inc. 0.07% Add +0.5% 581,864 $51.5M
Jacobs Levy Equity Management, Inc. 0.20% Reduce -12.1% 570,402 $50.5M
Morgan Stanley 0.00% Add +12.8% 568,699 $50.3M
Polar Capital Holdings Plc 0.29% Reduce -13.6% 541,379 $47.9M
Woodline Partners LP 0.31% Add +0.1% 540,738 $47.9M
Man Group plc 0.14% Add +400.1% 519,737 $46.0M
Braidwell LP 2.03% New 439,968 $38.9M
Susquehanna International Group, LLP 0.06% Add +202.9% 412,540 $36.5M
Emerald Advisers, LLC 1.60% Reduce -3.6% 401,644 $35.5M
D. E. Shaw & Co. 0.04% Add +7.5% 388,986 $34.4M
Jane Street Group, LLC 0.06% Reduce -7.9% 375,818 $33.3M
Ameriprise Financial Inc. 0.01% Add +6.9% 361,508 $32.0M
Jennison Associates LLC 0.02% Reduce -3.2% 348,817 $30.9M
Qube Research & Technologies Ltd 0.05% Reduce -3.7% 337,151 $29.8M
Casdin Capital, LLC 2.36% No change 326,378 $28.9M
Capital Research Global Investors 0.01% New 311,137 $27.5M
Fisher Asset Management 0.01% Reduce -3.8% 310,734 $27.5M
Bank of New York Mellon Corp 0.01% Add +1.2% 307,018 $27.2M
Citigroup Inc. 0.02% Add +220.3% 304,838 $27.0M
Ensign Peak Advisors, Inc 0.05% Add +10.3% 303,732 $26.9M
Lord, Abbett & Co. LLC 0.10% Reduce -13.9% 288,472 $25.5M
TD Asset Management Inc 0.02% Reduce -6.3% 284,372 $25.2M
Massachusetts Financial Services Co. 0.01% Add +0.4% 270,996 $24.0M
Nuveen, LLC 0.01% — 267,660 $23.4M
Sofinnova Investments, Inc. 1.74% New 261,039 $23.1M
Emerald Mutual Fund Advisers Trust 1.62% Reduce -7.0% 250,158 $22.1M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% Add +1.9% 244,411 $21.6M
Driehaus Capital Management LLC 0.21% New 242,938 $21.5M
Voya Investment Management LLC 0.03% Add +17.7% 241,672 $21.4M
Novo Holdings A/S 1.54% Add +30.8% 228,804 $20.3M
UBS Group AG 0.00% Add +8.3% 213,805 $18.9M
Panagora Asset Management Inc. 0.09% Add +187.9% 205,582 $18.2M
Deutsche Bank AG 0.01% Reduce -23.5% 199,937 $17.7M
Raymond James Financial Inc. 0.01% Reduce -19.9% 193,812 $17.2M
Connor, Clark & Lunn Investment Management Ltd. 0.07% Add +28.9% 183,947 $16.3M
Russell Investments Group, Ltd. 0.02% Add +34.3% 169,115 $15.0M
Manufacturers Life Insurance Company, The 0.01% Reduce -7.0% 164,055 $14.5M
DAFNA Capital Management LLC 3.87% Add +1.7% 152,263 $13.5M
AQR Capital Management 0.01% Add +2.5% 148,271 $13.1M
Integral Health Asset Management, LLC 1.42% Reduce -47.3% 145,000 $12.8M
Granahan Investment Management, LLC 0.64% Add +2.0% 144,756 $12.8M
Franklin Resources Inc. 0.00% Add +272.0% 136,111 $12.0M
Segall Bryant & Hamill, LLC 0.18% Reduce -2.7% 135,909 $12.0M
Barclays PLC 0.01% Reduce -31.5% 129,595 $11.5M
Swiss National Bank 0.01% Reduce -1.2% 123,100 $10.9M
Ikarian Capital, LLC 3.28% Reduce -32.8% 113,904 $10.1M
Orion Investment Co 3.95% Add +0.3% 109,033 $9.7M
Rafferty Asset Management, LLC 0.04% Add +11.7% 99,320 $8.8M
Peregrine Capital Management LLC 0.28% Reduce -2.7% 96,149 $8.5M
Legal & General Group Plc 0.00% Add +1.2% 95,666 $8.5M
Prudential Financial Inc. 0.01% Reduce -7.0% 93,468 $8.3M
First Turn Management, LLC 1.64% Add +37.1% 92,033 $8.1M
Rhumbline Advisers 0.01% Add +6.2% 91,933 $8.1M
Capital Fund Management S.A. 0.10% Add +1.8% 91,492 $8.1M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.02% New 84,780 $7.5M
Aquilo Capital Management, LLC 20.03% Reduce -35.2% 83,926 $7.4M
BIT Capital GmbH 0.83% Reduce -1.4% 77,802 $6.9M
California Public Employees Retirement System 0.00% Reduce -1.1% 77,556 $6.9M
Assenagon Asset Management S.A. 0.01% Reduce -21.7% 76,270 $6.8M
Oberweis Asset Management Inc./ 0.33% No change 75,000 $6.6M
Aquatic Capital Management LLC 0.17% Add +56.7% 74,574 $6.6M
Ally Bridge Group (NY) LLC 5.92% Add +32.7% 74,192 $6.6M
EFG Asset Management (North America) Corp. 1.08% Reduce -1.2% 73,388 $6.5M
Sei Investments Co. 0.01% Add +0.1% 70,463 $6.2M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.02% No change 69,887 $6.2M
Avidity Partners Management LP 1.25% Reduce -61.2% 68,500 $6.1M
Algert Global LLC 0.15% Reduce -39.0% 68,420 $6.1M
Neuberger Berman Group LLC 0.01% Add +2.1% 67,794 $6.0M
State of Wisconsin Investment Board 0.01% Add +52.3% 64,066 $5.7M
Stempoint Capital LP 1.75% New 61,927 $5.5M
Balyasny Asset Management L.P. 0.01% Reduce -41.2% 60,282 $5.3M
California State Teachers Retirement System 0.01% Reduce -1.1% 58,588 $5.2M
Hillsdale Investment Management Inc. 0.24% Add +3.1% 52,400 $4.6M
Tri Locum Partners LP 2.27% New 50,000 $4.4M
Alyeska Investment Group, L.P. 0.02% New 50,000 $4.4M
PFM Health Sciences, LP 0.32% Add +8.4% 46,453 $4.1M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.01% Add +6.3% 45,534 $4.0M
Canada Pension Plan Investment Board 0.00% Add +129.8% 45,500 $4.0M
Schonfeld Strategic Advisors LLC 0.03% Add +243.2% 45,300 $4.0M
Jefferies Financial Group Inc. 0.07% Reduce -4.8% 45,200 $4.0M
Frontier Capital Management Co. LLC 0.04% Reduce -59.1% 42,984 $3.8M
Walleye Capital LLC 0.05% Add +51.3% 42,195 $3.7M
Essex Investment Management Co. LLC 0.77% Reduce -9.2% 41,525 $3.7M
Intech Investment Management LLC 0.04% Add +26.7% 40,014 $3.5M
Envestnet Asset Management Inc. 0.00% Add +24.2% 39,893 $3.5M
Patient Square Capital LP 1.41% New 38,500 $3.4M
Thematics Asset Management 0.17% Add +4452.2% 37,601 $3.3M
Dana Investment Advisors, Inc. 0.12% Reduce -3.9% 37,551 $3.3M
MetLife Investment Management, LLC 0.02% Reduce -1.5% 37,514 $3.3M
Silverarc Capital Management, LLC 0.69% New 37,345 $3.3M
Prosight Management, LP 1.06% Reduce -45.5% 36,512 $3.2M
Boothbay Fund Management, LLC 0.12% Reduce -26.3% 36,454 $3.2M
Wells Fargo & Company 0.00% Reduce -13.3% 35,336 $3.1M
Axiom Investors LLC 0.03% Reduce -20.6% 34,842 $3.1M
NBW Capital LLC 0.68% Reduce -21.0% 34,678 $3.1M
Waverly Advisors, LLC 0.04% New 34,678 $3.1M
Mutual of America Capital Management LLC 0.04% Add +7.5% 34,521 $3.1M
F/m Investments LLC 0.12% Add +6.3% 33,276 $2.9M
Synovus Financial Corp. 0.04% Add +31.1% 32,156 $2.8M
Cinctive Capital Management LP 0.22% Reduce -67.5% 31,194 $2.8M
Corebridge Financial, Inc. 0.02% Reduce -1.5% 31,151 $2.8M
Janus Henderson Group PLC 0.00% No change 28,749 $2.5M
Jain Global LLC 0.05% Add +84.5% 27,621 $2.4M
Fieldview Capital Management, LLC 0.34% Reduce -29.8% 27,430 $2.4M
Royal Bank of Canada 0.00% Add +200.2% 26,814 $2.4M
Pathstone Holdings, LLC 0.01% Add +20.8% 26,445 $2.3M
Fred Alger Management, LLC 0.01% Add +0.2% 25,681 $2.3M
DekaBank Deutsche Girozentrale 0.00% No change 25,883 $2.3M
Citadel Advisors 0.00% Reduce -96.1% 25,608 $2.3M
Erste Asset Management GmbH 0.03% No change 25,100 $2.2M
Squarepoint Ops LLC 0.01% Reduce -90.5% 25,106 $2.2M
Engineers Gate Manager LP 0.04% Reduce -23.0% 24,689 $2.2M
State of New Jersey Common Pension Fund D 0.01% Reduce -10.9% 22,824 $2.0M
Moody Aldrich Partners LLC 0.41% New 22,331 $2.0M
Tudor Investment Corporation 0.02% Add +171.7% 22,011 $1.9M
Nomura Asset Management Co. Ltd. 0.01% Add +23.8% 21,935 $1.9M
Y-Intercept (Hong Kong) Ltd 0.13% New 21,522 $1.9M
Creative Planning 0.00% Add +8.1% 21,065 $1.9M
Tema ETFs LLC 0.55% Reduce -6.7% 20,972 $1.9M
NEOS Investment Management LLC 0.04% Add +22.6% 20,972 $1.9M
Granite Investment Partners, LLC 0.09% Reduce -10.1% 20,914 $1.9M
Profund Advisors LLC 0.08% Add +17.4% 20,840 $1.8M
New York State Common Retirement Fund 0.00% Add +1.5% 19,820 $1.8M
Handelsbanken Fonder AB 0.01% No change 18,651 $1.7M
Dimensional Fund Advisors LP 0.00% Reduce -53.7% 18,604 $1.6M
Arizona State Retirement System 0.01% Reduce -0.8% 18,202 $1.6M
Royce & Associates LP 0.02% New 18,001 $1.6M
Verition Fund Management LLC 0.01% Reduce -50.9% 17,213 $1.5M
Lazard Asset Management LLC 0.00% Add +1149.1% 17,212 $1.5M
Teacher Retirement System of Texas 0.01% Reduce -8.9% 17,097 $1.5M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +6.7% 17,004 $1.5M
Torray Investment Partners LLC 0.22% Add +1.1% 16,679 $1.5M
ProShare Advisors LLC 0.00% Reduce -20.4% 16,650 $1.5M
LPL Financial LLC 0.00% Add +103.7% 16,205 $1.4M
Mackenzie Financial Corp. 0.00% Add +14.2% 16,196 $1.4M
Principal Financial Group Inc. 0.00% Reduce -0.7% 16,078 $1.4M
Martingale Asset Management L P 0.03% Reduce -3.1% 15,493 $1.4M
Victory Capital Management Inc. 0.00% Reduce -4.5% 15,305 $1.4M
Diversified Trust Co. 0.03% Add +105.3% 15,226 $1.3M
State Board of Administration of Florida Retirement System 0.00% No change 15,172 $1.3M
SCS Capital Management LLC 0.02% New 15,163 $1.3M
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.03% Reduce -26.2% 14,865 $1.3M
Oak Ridge Investments LLC 0.11% Add +2.5% 14,547 $1.3M
Cibc World Markets Corp. 0.01% Add +137.1% 14,109 $1.2M
Guggenheim Capital LLC 0.01% Add +5.2% 13,827 $1.2M
S&co Inc. 0.08% Add +38.0% 13,795 $1.2M
Police & Firemen's Retirement System of New Jersey 0.01% No change 13,577 $1.2M
Ieq Capital, LLC 0.01% Add +28.5% 13,059 $1.2M
Knights of Columbus Asset Advisors LLC 0.08% Add +2.7% 12,995 $1.2M
China Universal Asset Management Co., Ltd. 0.11% Reduce -4.8% 12,818 $1.1M
KLP Kapitalforvaltning As 0.01% Reduce -4.7% 12,300 $1.1M
Group One Trading LLC 0.04% Reduce -75.7% 11,452 $1.0M
Fox Run Management, L.L.C. 0.16% Add +11.5% 11,445 $1.0M
Sectoral Asset Management Inc. 0.77% Reduce -10.6% 11,235 $994K
Los Angeles Capital Management LLC 0.00% Reduce -0.4% 11,138 $986K
Pitcairn Co. 0.06% Add +4.1% 11,047 $978K
Ami Asset Management Corp. 0.06% New 10,964 $970K
Teachers Retirement System of the State of Kentucky 0.01% Reduce -35.0% 10,743 $951K
LMR Partners LLP 0.03% New 10,689 $946K
Marshall Wace, LLP 0.00% Reduce -93.5% 10,600 $938K
HSBC Holdings PLC 0.00% Reduce -47.5% 10,511 $914K
Dark Forest Capital Management LP 0.04% Add +19.6% 10,261 $908K
Schroder Investment Management Group 0.00% Reduce -73.4% 10,231 $908K
Voloridge Investment Management, LLC 0.00% Reduce -95.3% 10,135 $897K
Zimmer Partners, LP 0.02% Reduce -71.4% 9,620 $851K
E Fund Management Co., Ltd. 0.04% Add +46.9% 9,282 $822K
Allianz Asset Management GmbH 0.00% Reduce -34.1% 9,100 $805K
Henshaw Capital LLC 0.03% No change 8,475 $750K
US Bancorp \de 0.00% Reduce -16.6% 8,326 $737K
Tower Research Capital LLC (TRC) 0.02% Add +12.5% 8,175 $711K
Captrust Financial Advisors 0.00% Reduce -5.1% 7,909 $700K
CANADA LIFE ASSURANCE Co 0.00% Add +22.5% 7,621 $676K
Crestwood Advisors Group, LLC 0.01% New 7,630 $675K
Mariner, LLC 0.00% Add +133.6% 7,482 $662K
XTX Topco Ltd 0.03% Reduce -34.4% 7,311 $647K
SG Americas Securities, LLC 0.00% Add +70.1% 7,276 $644K
Caption Management, LLC 0.03% New 7,000 $620K
Cetera Investment Advisers 0.00% Reduce -0.0% 6,858 $607K
Pallas Capital Advisors LLC 0.03% Add +19.4% 6,843 $606K
DNB Asset Management AS 0.00% Reduce -4.8% 6,802 $602K
Comerica Bank 0.00% Reduce -48.4% 6,763 $599K
STRS Ohio 0.00% Add +3.1% 6,700 $593K
Public Employees Retirement Association of Colorado 0.00% No change 6,512 $576K
Ameritas Investment Partners, Inc. 0.02% Reduce -2.4% 6,492 $575K
Graham Capital Management, L.P. 0.03% Reduce -75.3% 6,237 $552K
PDT Partners, LLC 0.04% Add +96.8% 6,098 $540K
Neo Ivy Capital Management 0.16% New 5,754 $509K
Advisors Asset Management, Inc. 0.01% Reduce -5.7% 5,553 $491K
Mraz, Amerine & Associates, Inc. 0.08% Add +0.8% 5,391 $478K
Cwm, LLC 0.00% Add +62.3% 5,321 $471K
Fiduciary Trust Co 0.01% Reduce -49.3% 5,152 $456K
Stephens Inc. 0.01% Add +38.0% 5,084 $450K
Values First Advisors, Inc. 0.26% Add +1.3% 5,033 $446K
BNP Paribas Financial Markets 0.00% Reduce -59.7% 5,032 $445K
Xponance LLC 0.00% Add +5.0% 5,021 $444K
Allspring Global Investments Holdings, LLC 0.00% Add +53.9% 4,957 $426K
Nebula Research & Development LLC 0.04% Reduce -39.1% 4,725 $418K
Simplex Trading, LLC 0.01% Reduce -28.8% 4,704 $416K
Cerity Partners LLC 0.00% Add +40.3% 4,628 $410K
Kennedy Capital Management LLC 0.01% Add +1.3% 4,623 $409K
Magnetar Financial LLC 0.01% Add +48.1% 4,568 $404K
Farringdon Capital, Ltd. 0.20% New 4,553 $403K
Gilbert & Cook, Inc. 0.06% Add +0.1% 4,358 $386K
SIH Partners, LLLP 0.03% New 4,027 $356K
Farallon Capital Management, L.L.C. 0.00% No change 4,000 $354K
Citizens Financial Group Inc. 0.01% Add +0.4% 3,937 $348K
Virtus Investment Advisers, LLC 0.09% New 3,878 $343K
Vanguard Personalized Indexing Management, LLC 0.01% Reduce -0.4% 3,793 $336K
Calamos Advisors LLC 0.00% New 3,721 $329K
Aigen Investment Management, LP 0.05% Reduce -17.4% 3,706 $328K
Gsa Capital Partners LLP 0.03% New 3,688 $326K
NewEdge Wealth, LLC 0.01% Add +5.2% 3,625 $321K
Intrust Bank NA 0.03% Add +3.4% 3,557 $315K
Susquehanna Fundamental Investments, LLC 0.01% Reduce -93.8% 3,470 $307K
Wealth Enhancement Advisory Services, LLC 0.00% New 3,353 $297K
Bantamac Capital, LLC 0.14% New 3,347 $296K
O'shaughnessy Asset Management, LLC 0.00% Add +4.8% 3,346 $296K
Fifth Third Bancorp 0.00% Add +4.8% 3,221 $285K
PEAK6 LLC 0.01% Reduce -59.9% 3,210 $284K
First Trust Advisors LP 0.00% Reduce -94.1% 3,180 $281K
Glenmede Trust Co. NA 0.00% New 3,162 $280K
Blueshift Asset Management, LLC 0.11% New 3,086 $273K
Garda Capital Partners LP 0.15% New 2,984 $264K
KBC Group NV 0.00% Add +3.7% 2,723 $241K
Birchview Capital, LP 0.21% No change 2,700 $239K
Lanark Financial, Inc. 0.02% — 2,648 $234K
Truist Financial Corp. 0.00% Add +3.2% 2,612 $231K
Steward Partners Investment Advisory, LLC 0.00% No change 2,610 $231K
Atria Investments, Inc 0.00% New 2,491 $220K
Inceptionr LLC 0.06% New 2,416 $214K
Amalgamated Bank 0.00% Add +2.2% 2,202 $195K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -1.2% 2,091 $186K
Nisa Investment Advisors, LLC 0.00% Add +4.8% 1,947 $172K
AlphaQuest LLC 0.02% Add +1724.2% 1,733 $153K
PNC Financial Services Group, Inc. 0.00% Add +1.4% 1,674 $148K
Osaic Holdings, Inc. 0.00% Add +31.1% 1,652 $146K
GF Fund Management Co. LTD. 0.00% Add +21.9% 1,626 $144K
Exchange Traded Concepts, LLC 0.00% Reduce -31.2% 1,383 $122K
Coldstream Capital Management Inc. 0.00% New 1,144 $101K
Covestor Ltd 0.07% Add +15.9% 1,128 $100K
Van Eck Associates Corp. 0.00% No change 1,116 $99K
CI Investments Inc. 0.00% Reduce -37.8% 1,021 $90K
BI Asset Management Fondsmaeglerselskab A/S 0.00% New 988 $87K
Headlands Technologies LLC 0.01% Add +25.0% 936 $83K
Northwestern Mutual Wealth Management Co. 0.00% Add +1.8% 869 $77K
Compass Wealth Management LLC 0.02% No change 750 $66K
Vega Investment Solutions 0.01% New 597 $53K
Ostrum Asset Management 0.00% New 597 $53K
Leonteq Securities AG 0.00% Reduce -40.7% 425 $38K
Tortoise Investment Management, LLC 0.00% No change 396 $35K
GAMMA Investing LLC 0.00% Add +36.4% 326 $29K
Lindbrook Capital, LLC 0.00% Add +3.0% 309 $27K
Optiver Holding B.V. 0.00% New 309 $27K
Danske Bank A/S 0.00% No change 300 $27K
Parallel Advisors, LLC 0.00% Reduce -9.5% 275 $24K
Huntington National Bank 0.00% Reduce -16.6% 247 $22K
Picton Mahoney Asset Management 0.00% Add +442.5% 217 $20K
Asset Management One Co., Ltd. 0.00% Reduce -77.7% 221 $20K
Daiwa Securities Group Inc. 0.00% No change 210 $19K
Crowley Wealth Management, Inc. 0.02% No change 200 $18K
Harbour Investments, Inc. 0.00% No change 200 $18K
EverSource Wealth Advisors, LLC 0.00% Add +17.3% 190 $17K
Bessemer Group Inc. 0.00% Reduce -32.5% 160 $14K
Signaturefd, LLC 0.00% Reduce -15.0% 153 $14K
Smartleaf Asset Management LLC 0.00% Reduce -23.6% 149 $13K
True Wealth Design, LLC 0.01% Reduce -0.7% 149 $13K
Rise Advisors, LLC 0.01% Reduce -14.1% 134 $12K
UMB Bank, n.a. 0.00% No change 127 $11K
AdvisorNet Financial, Inc 0.00% No change 119 $11K
Arax Advisory Partners 0.00% Add +134.0% 117 $10K
Blue Trust, Inc. 0.00% No change 113 $10K
Parkside Financial Bank & Trust 0.00% Add +29.8% 109 $10K
Clearstead Trust, LLC 0.00% No change 101 $9K
TD Capital Management LLC 0.00% New 100 $9K
Farmers & Merchants Investments Inc. 0.00% No change 100 $9K
Truvestments Capital LLC 0.00% No change 98 $9K
Accent Capital Management, LLC 0.00% New 80 $7K
Federation des caisses Desjardins du Quebec 0.00% New 80 $7K
SVB Wealth LLC 0.00% New 77 $7K
Cullen/Frost Bankers, Inc. 0.00% No change 70 $6K
Global Financial Private Client, LLC 0.00% New 66 $6K
Sterling Capital Management LLC 0.00% Add +1.5% 66 $6K
Rothschild Investment LLC 0.00% No change 65 $6K
Farther Finance Advisors, LLC 0.00% Add +43.5% 66 $6K
Quent Capital, LLC 0.00% No change 61 $5K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% No change 58 $5K
Private Wealth Management Group, LLC 0.00% No change 49 $4K
Versant Capital Management, Inc 0.00% Reduce -35.6% 47 $4K
Allworth Financial LP 0.00% Add +235.7% 47 $4K
Highline Wealth Partners LLC 0.00% New 42 $4K
WPG Advisers, LLC 0.00% Add +21.9% 39 $3K
Clearstead Advisors, LLC 0.00% Reduce -39.7% 38 $3K
Principal Securities, Inc. 0.00% No change 25 $2K
CENTRAL TRUST Co 0.00% No change 23 $2K
First Horizon Advisors, Inc. 0.00% No change 21 $2K
Stephens Consulting, LLC 0.00% New 20 $2K
Wolff Wiese Magana LLC 0.00% No change 19 $2K
Assetmark, Inc. 0.00% Add +21.4% 17 $2K
Jones Financial Companies LLLP 0.00% New 16 $1K
MassMutual Private Wealth & Trust, FSB 0.00% Add +7.1% 15 $1K
Bayforest Capital Ltd 0.00% Reduce -99.5% 13 $1K
Riggs Asset Managment Co. Inc. 0.00% No change 12 $1K
Transamerica Financial Advisors, LLC 0.00% No change 1 $1K
SBI Securities Co., Ltd. 0.00% Add +100.0% 10 $885
Cornerstone Planning Group LLC 0.00% New 9 $772
Montag A & Associates Inc. 0.00% New 9 $763
Bokf, NA 0.00% No change 8 $708
Geneos Wealth Management Inc. 0.00% New 8 $708
Amundi 0.00% New 8 $697
Physician Wealth Advisors, Inc. 0.00% New 7 $620
Brooklyn Investment Group 0.00% New 7 $620
ORG Partners LLC 0.00% New 7 $601
MAI Capital Management 0.00% New 6 $532
SouthState Bank Corp 0.00% New 5 $443
Wilmington Savings Fund Society, FSB 0.00% No change 5 $443
Creative Financial Designs Inc. 0.00% New 4 $354
NewEdge Advisors, LLC 0.00% No change 4 $354
American Capital Advisory, LLC 0.00% New 3 $266
Quadrant Capital Group LLC 0.00% No change 3 $266
TD Private Client Wealth LLC 0.00% New 2 $177
Larson Financial Group LLC 0.00% New 2 $177
Innovative Advisory Group, LLC 0.00% No change 1 $89
National Bank of Canada 0.00% New 1 $89
TFC Financial Management, Inc. 0.00% New 1 $89
Capital Advisors, Ltd. LLC 0.00% No change 3 $0

"% of holder's portfolio" is BPMC's weight in each manager's 13F, not the share of Blueprint Medicines Corp. the manager owns.