Blueprint MedicinesBPMC
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 353 institutions reported holding Blueprint Medicines Corp. (BPMC) in their 13F filings, up 7 from Q4 2024. 61 opened new positions and 52 sold out. The largest holders were BlackRock, Inc. ($594.0M), Vanguard Group Inc. ($587.8M) and T. Rowe Price Associates Inc. ($479.4M). 6 famous investors held it, including Israel Englander (0.1% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Blueprint Medicines Corp.
- CUSIP
- 09627Y109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 61 | $221.5M |
| Exits | 52 | $121.9M |
All 13F filers, Q4 2024 → Q1 2025: 9,996,684 shares bought and 7,882,214 shares sold, net +2,114,470 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 353 holders
| BlackRock, Inc. | 0.01% | Reduce -2.3% | 6,710,708 | $594.0M |
| Vanguard Group Inc. | 0.01% | Reduce -2.0% | 6,640,523 | $587.8M |
| T. Rowe Price Associates Inc. | 0.06% | Reduce -4.6% | 5,415,837 | $479.4M |
| Avoro Capital Advisors LLC | 5.32% | Add +224.9% | 3,850,000 | $340.8M |
| Wellington Management Group LLP | 0.05% | Reduce -28.2% | 3,073,306 | $272.0M |
| State Street Corp. | 0.01% | Add +7.4% | 2,684,117 | $237.6M |
| JPMorgan Chase & Co. | 0.02% | Add +116.9% | 2,506,514 | $221.9M |
| Geode Capital Management, LLC | 0.01% | Add +2.2% | 1,522,647 | $134.8M |
| FMR LLC | 0.01% | Reduce -36.2% | 1,433,169 | $126.8M |
| William Blair Investment Management, LLC | 0.36% | Reduce -26.5% | 1,429,668 | $126.5M |
| T. Rowe Price Investment Management, Inc. | 0.08% | Add +86.9% | 1,302,810 | $115.3M |
| Macquarie Group Ltd. | 0.14% | Add +2.2% | 1,286,897 | $113.9M |
| Alliancebernstein L.P. | 0.04% | Add +5.1% | 1,196,240 | $105.9M |
| Rock Springs Capital Management LP | 5.12% | Reduce -8.1% | 1,007,569 | $89.2M |
| Invesco Ltd. | 0.02% | Add +2.5% | 984,674 | $87.2M |
| Pictet Asset Management Holding SA | 0.09% | Reduce -19.4% | 954,596 | $84.5M |
| Goldman Sachs Group Inc. | 0.02% | Reduce -11.4% | 926,668 | $82.0M |
| Alkeon Capital Management LLC | 0.47% | Add +12.5% | 900,628 | $79.7M |
| Hood River Capital Management LLC | 1.36% | Add +2.3% | 900,205 | $79.7M |
| American Century Companies Inc. | 0.05% | Add +3.3% | 866,763 | $76.7M |
| Eventide Asset Management, LLC | 1.52% | Add +0.0% | 862,549 | $76.3M |
| Siren, L.L.C. | 3.63% | New | 726,167 | $64.3M |
| Bank of America Corp. | 0.01% | Add +81.5% | 716,906 | $63.5M |
| Millennium Management | 0.06% | Reduce -6.2% | 691,395 | $61.2M |
| Clearbridge Investments, LLC | 0.05% | Add +36.9% | 671,617 | $59.4M |
| Norges Bank | 0.01% | Reduce -15.2% | 602,927 | $53.4M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -0.8% | 599,721 | $53.1M |
| Northern Trust Corp. | 0.01% | Reduce -3.1% | 589,559 | $52.2M |
| Brown Advisory Inc. | 0.07% | Add +0.5% | 581,864 | $51.5M |
| Jacobs Levy Equity Management, Inc. | 0.20% | Reduce -12.1% | 570,402 | $50.5M |
| Morgan Stanley | 0.00% | Add +12.8% | 568,699 | $50.3M |
| Polar Capital Holdings Plc | 0.29% | Reduce -13.6% | 541,379 | $47.9M |
| Woodline Partners LP | 0.31% | Add +0.1% | 540,738 | $47.9M |
| Man Group plc | 0.14% | Add +400.1% | 519,737 | $46.0M |
| Braidwell LP | 2.03% | New | 439,968 | $38.9M |
| Susquehanna International Group, LLP | 0.06% | Add +202.9% | 412,540 | $36.5M |
| Emerald Advisers, LLC | 1.60% | Reduce -3.6% | 401,644 | $35.5M |
| D. E. Shaw & Co. | 0.04% | Add +7.5% | 388,986 | $34.4M |
| Jane Street Group, LLC | 0.06% | Reduce -7.9% | 375,818 | $33.3M |
| Ameriprise Financial Inc. | 0.01% | Add +6.9% | 361,508 | $32.0M |
| Jennison Associates LLC | 0.02% | Reduce -3.2% | 348,817 | $30.9M |
| Qube Research & Technologies Ltd | 0.05% | Reduce -3.7% | 337,151 | $29.8M |
| Casdin Capital, LLC | 2.36% | No change | 326,378 | $28.9M |
| Capital Research Global Investors | 0.01% | New | 311,137 | $27.5M |
| Fisher Asset Management | 0.01% | Reduce -3.8% | 310,734 | $27.5M |
| Bank of New York Mellon Corp | 0.01% | Add +1.2% | 307,018 | $27.2M |
| Citigroup Inc. | 0.02% | Add +220.3% | 304,838 | $27.0M |
| Ensign Peak Advisors, Inc | 0.05% | Add +10.3% | 303,732 | $26.9M |
| Lord, Abbett & Co. LLC | 0.10% | Reduce -13.9% | 288,472 | $25.5M |
| TD Asset Management Inc | 0.02% | Reduce -6.3% | 284,372 | $25.2M |
| Massachusetts Financial Services Co. | 0.01% | Add +0.4% | 270,996 | $24.0M |
| Nuveen, LLC | 0.01% | — | 267,660 | $23.4M |
| Sofinnova Investments, Inc. | 1.74% | New | 261,039 | $23.1M |
| Emerald Mutual Fund Advisers Trust | 1.62% | Reduce -7.0% | 250,158 | $22.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +1.9% | 244,411 | $21.6M |
| Driehaus Capital Management LLC | 0.21% | New | 242,938 | $21.5M |
| Voya Investment Management LLC | 0.03% | Add +17.7% | 241,672 | $21.4M |
| Novo Holdings A/S | 1.54% | Add +30.8% | 228,804 | $20.3M |
| UBS Group AG | 0.00% | Add +8.3% | 213,805 | $18.9M |
| Panagora Asset Management Inc. | 0.09% | Add +187.9% | 205,582 | $18.2M |
| Deutsche Bank AG | 0.01% | Reduce -23.5% | 199,937 | $17.7M |
| Raymond James Financial Inc. | 0.01% | Reduce -19.9% | 193,812 | $17.2M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.07% | Add +28.9% | 183,947 | $16.3M |
| Russell Investments Group, Ltd. | 0.02% | Add +34.3% | 169,115 | $15.0M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -7.0% | 164,055 | $14.5M |
| DAFNA Capital Management LLC | 3.87% | Add +1.7% | 152,263 | $13.5M |
| AQR Capital Management | 0.01% | Add +2.5% | 148,271 | $13.1M |
| Integral Health Asset Management, LLC | 1.42% | Reduce -47.3% | 145,000 | $12.8M |
| Granahan Investment Management, LLC | 0.64% | Add +2.0% | 144,756 | $12.8M |
| Franklin Resources Inc. | 0.00% | Add +272.0% | 136,111 | $12.0M |
| Segall Bryant & Hamill, LLC | 0.18% | Reduce -2.7% | 135,909 | $12.0M |
| Barclays PLC | 0.01% | Reduce -31.5% | 129,595 | $11.5M |
| Swiss National Bank | 0.01% | Reduce -1.2% | 123,100 | $10.9M |
| Ikarian Capital, LLC | 3.28% | Reduce -32.8% | 113,904 | $10.1M |
| Orion Investment Co | 3.95% | Add +0.3% | 109,033 | $9.7M |
| Rafferty Asset Management, LLC | 0.04% | Add +11.7% | 99,320 | $8.8M |
| Peregrine Capital Management LLC | 0.28% | Reduce -2.7% | 96,149 | $8.5M |
| Legal & General Group Plc | 0.00% | Add +1.2% | 95,666 | $8.5M |
| Prudential Financial Inc. | 0.01% | Reduce -7.0% | 93,468 | $8.3M |
| First Turn Management, LLC | 1.64% | Add +37.1% | 92,033 | $8.1M |
| Rhumbline Advisers | 0.01% | Add +6.2% | 91,933 | $8.1M |
| Capital Fund Management S.A. | 0.10% | Add +1.8% | 91,492 | $8.1M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | New | 84,780 | $7.5M |
| Aquilo Capital Management, LLC | 20.03% | Reduce -35.2% | 83,926 | $7.4M |
| BIT Capital GmbH | 0.83% | Reduce -1.4% | 77,802 | $6.9M |
| California Public Employees Retirement System | 0.00% | Reduce -1.1% | 77,556 | $6.9M |
| Assenagon Asset Management S.A. | 0.01% | Reduce -21.7% | 76,270 | $6.8M |
| Oberweis Asset Management Inc./ | 0.33% | No change | 75,000 | $6.6M |
| Aquatic Capital Management LLC | 0.17% | Add +56.7% | 74,574 | $6.6M |
| Ally Bridge Group (NY) LLC | 5.92% | Add +32.7% | 74,192 | $6.6M |
| EFG Asset Management (North America) Corp. | 1.08% | Reduce -1.2% | 73,388 | $6.5M |
| Sei Investments Co. | 0.01% | Add +0.1% | 70,463 | $6.2M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.02% | No change | 69,887 | $6.2M |
| Avidity Partners Management LP | 1.25% | Reduce -61.2% | 68,500 | $6.1M |
| Algert Global LLC | 0.15% | Reduce -39.0% | 68,420 | $6.1M |
| Neuberger Berman Group LLC | 0.01% | Add +2.1% | 67,794 | $6.0M |
| State of Wisconsin Investment Board | 0.01% | Add +52.3% | 64,066 | $5.7M |
| Stempoint Capital LP | 1.75% | New | 61,927 | $5.5M |
| Balyasny Asset Management L.P. | 0.01% | Reduce -41.2% | 60,282 | $5.3M |
| California State Teachers Retirement System | 0.01% | Reduce -1.1% | 58,588 | $5.2M |
| Hillsdale Investment Management Inc. | 0.24% | Add +3.1% | 52,400 | $4.6M |
| Tri Locum Partners LP | 2.27% | New | 50,000 | $4.4M |
| Alyeska Investment Group, L.P. | 0.02% | New | 50,000 | $4.4M |
| PFM Health Sciences, LP | 0.32% | Add +8.4% | 46,453 | $4.1M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Add +6.3% | 45,534 | $4.0M |
| Canada Pension Plan Investment Board | 0.00% | Add +129.8% | 45,500 | $4.0M |
| Schonfeld Strategic Advisors LLC | 0.03% | Add +243.2% | 45,300 | $4.0M |
| Jefferies Financial Group Inc. | 0.07% | Reduce -4.8% | 45,200 | $4.0M |
| Frontier Capital Management Co. LLC | 0.04% | Reduce -59.1% | 42,984 | $3.8M |
| Walleye Capital LLC | 0.05% | Add +51.3% | 42,195 | $3.7M |
| Essex Investment Management Co. LLC | 0.77% | Reduce -9.2% | 41,525 | $3.7M |
| Intech Investment Management LLC | 0.04% | Add +26.7% | 40,014 | $3.5M |
| Envestnet Asset Management Inc. | 0.00% | Add +24.2% | 39,893 | $3.5M |
| Patient Square Capital LP | 1.41% | New | 38,500 | $3.4M |
| Thematics Asset Management | 0.17% | Add +4452.2% | 37,601 | $3.3M |
| Dana Investment Advisors, Inc. | 0.12% | Reduce -3.9% | 37,551 | $3.3M |
| MetLife Investment Management, LLC | 0.02% | Reduce -1.5% | 37,514 | $3.3M |
| Silverarc Capital Management, LLC | 0.69% | New | 37,345 | $3.3M |
| Prosight Management, LP | 1.06% | Reduce -45.5% | 36,512 | $3.2M |
| Boothbay Fund Management, LLC | 0.12% | Reduce -26.3% | 36,454 | $3.2M |
| Wells Fargo & Company | 0.00% | Reduce -13.3% | 35,336 | $3.1M |
| Axiom Investors LLC | 0.03% | Reduce -20.6% | 34,842 | $3.1M |
| NBW Capital LLC | 0.68% | Reduce -21.0% | 34,678 | $3.1M |
| Waverly Advisors, LLC | 0.04% | New | 34,678 | $3.1M |
| Mutual of America Capital Management LLC | 0.04% | Add +7.5% | 34,521 | $3.1M |
| F/m Investments LLC | 0.12% | Add +6.3% | 33,276 | $2.9M |
| Synovus Financial Corp. | 0.04% | Add +31.1% | 32,156 | $2.8M |
| Cinctive Capital Management LP | 0.22% | Reduce -67.5% | 31,194 | $2.8M |
| Corebridge Financial, Inc. | 0.02% | Reduce -1.5% | 31,151 | $2.8M |
| Janus Henderson Group PLC | 0.00% | No change | 28,749 | $2.5M |
| Jain Global LLC | 0.05% | Add +84.5% | 27,621 | $2.4M |
| Fieldview Capital Management, LLC | 0.34% | Reduce -29.8% | 27,430 | $2.4M |
| Royal Bank of Canada | 0.00% | Add +200.2% | 26,814 | $2.4M |
| Pathstone Holdings, LLC | 0.01% | Add +20.8% | 26,445 | $2.3M |
| Fred Alger Management, LLC | 0.01% | Add +0.2% | 25,681 | $2.3M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 25,883 | $2.3M |
| Citadel Advisors | 0.00% | Reduce -96.1% | 25,608 | $2.3M |
| Erste Asset Management GmbH | 0.03% | No change | 25,100 | $2.2M |
| Squarepoint Ops LLC | 0.01% | Reduce -90.5% | 25,106 | $2.2M |
| Engineers Gate Manager LP | 0.04% | Reduce -23.0% | 24,689 | $2.2M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -10.9% | 22,824 | $2.0M |
| Moody Aldrich Partners LLC | 0.41% | New | 22,331 | $2.0M |
| Tudor Investment Corporation | 0.02% | Add +171.7% | 22,011 | $1.9M |
| Nomura Asset Management Co. Ltd. | 0.01% | Add +23.8% | 21,935 | $1.9M |
| Y-Intercept (Hong Kong) Ltd | 0.13% | New | 21,522 | $1.9M |
| Creative Planning | 0.00% | Add +8.1% | 21,065 | $1.9M |
| Tema ETFs LLC | 0.55% | Reduce -6.7% | 20,972 | $1.9M |
| NEOS Investment Management LLC | 0.04% | Add +22.6% | 20,972 | $1.9M |
| Granite Investment Partners, LLC | 0.09% | Reduce -10.1% | 20,914 | $1.9M |
| Profund Advisors LLC | 0.08% | Add +17.4% | 20,840 | $1.8M |
| New York State Common Retirement Fund | 0.00% | Add +1.5% | 19,820 | $1.8M |
| Handelsbanken Fonder AB | 0.01% | No change | 18,651 | $1.7M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -53.7% | 18,604 | $1.6M |
| Arizona State Retirement System | 0.01% | Reduce -0.8% | 18,202 | $1.6M |
| Royce & Associates LP | 0.02% | New | 18,001 | $1.6M |
| Verition Fund Management LLC | 0.01% | Reduce -50.9% | 17,213 | $1.5M |
| Lazard Asset Management LLC | 0.00% | Add +1149.1% | 17,212 | $1.5M |
| Teacher Retirement System of Texas | 0.01% | Reduce -8.9% | 17,097 | $1.5M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +6.7% | 17,004 | $1.5M |
| Torray Investment Partners LLC | 0.22% | Add +1.1% | 16,679 | $1.5M |
| ProShare Advisors LLC | 0.00% | Reduce -20.4% | 16,650 | $1.5M |
| LPL Financial LLC | 0.00% | Add +103.7% | 16,205 | $1.4M |
| Mackenzie Financial Corp. | 0.00% | Add +14.2% | 16,196 | $1.4M |
| Principal Financial Group Inc. | 0.00% | Reduce -0.7% | 16,078 | $1.4M |
| Martingale Asset Management L P | 0.03% | Reduce -3.1% | 15,493 | $1.4M |
| Victory Capital Management Inc. | 0.00% | Reduce -4.5% | 15,305 | $1.4M |
| Diversified Trust Co. | 0.03% | Add +105.3% | 15,226 | $1.3M |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,172 | $1.3M |
| SCS Capital Management LLC | 0.02% | New | 15,163 | $1.3M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.03% | Reduce -26.2% | 14,865 | $1.3M |
| Oak Ridge Investments LLC | 0.11% | Add +2.5% | 14,547 | $1.3M |
| Cibc World Markets Corp. | 0.01% | Add +137.1% | 14,109 | $1.2M |
| Guggenheim Capital LLC | 0.01% | Add +5.2% | 13,827 | $1.2M |
| S&co Inc. | 0.08% | Add +38.0% | 13,795 | $1.2M |
| Police & Firemen's Retirement System of New Jersey | 0.01% | No change | 13,577 | $1.2M |
| Ieq Capital, LLC | 0.01% | Add +28.5% | 13,059 | $1.2M |
| Knights of Columbus Asset Advisors LLC | 0.08% | Add +2.7% | 12,995 | $1.2M |
| China Universal Asset Management Co., Ltd. | 0.11% | Reduce -4.8% | 12,818 | $1.1M |
| KLP Kapitalforvaltning As | 0.01% | Reduce -4.7% | 12,300 | $1.1M |
| Group One Trading LLC | 0.04% | Reduce -75.7% | 11,452 | $1.0M |
| Fox Run Management, L.L.C. | 0.16% | Add +11.5% | 11,445 | $1.0M |
| Sectoral Asset Management Inc. | 0.77% | Reduce -10.6% | 11,235 | $994K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -0.4% | 11,138 | $986K |
| Pitcairn Co. | 0.06% | Add +4.1% | 11,047 | $978K |
| Ami Asset Management Corp. | 0.06% | New | 10,964 | $970K |
| Teachers Retirement System of the State of Kentucky | 0.01% | Reduce -35.0% | 10,743 | $951K |
| LMR Partners LLP | 0.03% | New | 10,689 | $946K |
| Marshall Wace, LLP | 0.00% | Reduce -93.5% | 10,600 | $938K |
| HSBC Holdings PLC | 0.00% | Reduce -47.5% | 10,511 | $914K |
| Dark Forest Capital Management LP | 0.04% | Add +19.6% | 10,261 | $908K |
| Schroder Investment Management Group | 0.00% | Reduce -73.4% | 10,231 | $908K |
| Voloridge Investment Management, LLC | 0.00% | Reduce -95.3% | 10,135 | $897K |
| Zimmer Partners, LP | 0.02% | Reduce -71.4% | 9,620 | $851K |
| E Fund Management Co., Ltd. | 0.04% | Add +46.9% | 9,282 | $822K |
| Allianz Asset Management GmbH | 0.00% | Reduce -34.1% | 9,100 | $805K |
| Henshaw Capital LLC | 0.03% | No change | 8,475 | $750K |
| US Bancorp \de | 0.00% | Reduce -16.6% | 8,326 | $737K |
| Tower Research Capital LLC (TRC) | 0.02% | Add +12.5% | 8,175 | $711K |
| Captrust Financial Advisors | 0.00% | Reduce -5.1% | 7,909 | $700K |
| CANADA LIFE ASSURANCE Co | 0.00% | Add +22.5% | 7,621 | $676K |
| Crestwood Advisors Group, LLC | 0.01% | New | 7,630 | $675K |
| Mariner, LLC | 0.00% | Add +133.6% | 7,482 | $662K |
| XTX Topco Ltd | 0.03% | Reduce -34.4% | 7,311 | $647K |
| SG Americas Securities, LLC | 0.00% | Add +70.1% | 7,276 | $644K |
| Caption Management, LLC | 0.03% | New | 7,000 | $620K |
| Cetera Investment Advisers | 0.00% | Reduce -0.0% | 6,858 | $607K |
| Pallas Capital Advisors LLC | 0.03% | Add +19.4% | 6,843 | $606K |
| DNB Asset Management AS | 0.00% | Reduce -4.8% | 6,802 | $602K |
| Comerica Bank | 0.00% | Reduce -48.4% | 6,763 | $599K |
| STRS Ohio | 0.00% | Add +3.1% | 6,700 | $593K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,512 | $576K |
| Ameritas Investment Partners, Inc. | 0.02% | Reduce -2.4% | 6,492 | $575K |
| Graham Capital Management, L.P. | 0.03% | Reduce -75.3% | 6,237 | $552K |
| PDT Partners, LLC | 0.04% | Add +96.8% | 6,098 | $540K |
| Neo Ivy Capital Management | 0.16% | New | 5,754 | $509K |
| Advisors Asset Management, Inc. | 0.01% | Reduce -5.7% | 5,553 | $491K |
| Mraz, Amerine & Associates, Inc. | 0.08% | Add +0.8% | 5,391 | $478K |
| Cwm, LLC | 0.00% | Add +62.3% | 5,321 | $471K |
| Fiduciary Trust Co | 0.01% | Reduce -49.3% | 5,152 | $456K |
| Stephens Inc. | 0.01% | Add +38.0% | 5,084 | $450K |
| Values First Advisors, Inc. | 0.26% | Add +1.3% | 5,033 | $446K |
| BNP Paribas Financial Markets | 0.00% | Reduce -59.7% | 5,032 | $445K |
| Xponance LLC | 0.00% | Add +5.0% | 5,021 | $444K |
| Allspring Global Investments Holdings, LLC | 0.00% | Add +53.9% | 4,957 | $426K |
| Nebula Research & Development LLC | 0.04% | Reduce -39.1% | 4,725 | $418K |
| Simplex Trading, LLC | 0.01% | Reduce -28.8% | 4,704 | $416K |
| Cerity Partners LLC | 0.00% | Add +40.3% | 4,628 | $410K |
| Kennedy Capital Management LLC | 0.01% | Add +1.3% | 4,623 | $409K |
| Magnetar Financial LLC | 0.01% | Add +48.1% | 4,568 | $404K |
| Farringdon Capital, Ltd. | 0.20% | New | 4,553 | $403K |
| Gilbert & Cook, Inc. | 0.06% | Add +0.1% | 4,358 | $386K |
| SIH Partners, LLLP | 0.03% | New | 4,027 | $356K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 4,000 | $354K |
| Citizens Financial Group Inc. | 0.01% | Add +0.4% | 3,937 | $348K |
| Virtus Investment Advisers, LLC | 0.09% | New | 3,878 | $343K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Reduce -0.4% | 3,793 | $336K |
| Calamos Advisors LLC | 0.00% | New | 3,721 | $329K |
| Aigen Investment Management, LP | 0.05% | Reduce -17.4% | 3,706 | $328K |
| Gsa Capital Partners LLP | 0.03% | New | 3,688 | $326K |
| NewEdge Wealth, LLC | 0.01% | Add +5.2% | 3,625 | $321K |
| Intrust Bank NA | 0.03% | Add +3.4% | 3,557 | $315K |
| Susquehanna Fundamental Investments, LLC | 0.01% | Reduce -93.8% | 3,470 | $307K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | New | 3,353 | $297K |
| Bantamac Capital, LLC | 0.14% | New | 3,347 | $296K |
| O'shaughnessy Asset Management, LLC | 0.00% | Add +4.8% | 3,346 | $296K |
| Fifth Third Bancorp | 0.00% | Add +4.8% | 3,221 | $285K |
| PEAK6 LLC | 0.01% | Reduce -59.9% | 3,210 | $284K |
| First Trust Advisors LP | 0.00% | Reduce -94.1% | 3,180 | $281K |
| Glenmede Trust Co. NA | 0.00% | New | 3,162 | $280K |
| Blueshift Asset Management, LLC | 0.11% | New | 3,086 | $273K |
| Garda Capital Partners LP | 0.15% | New | 2,984 | $264K |
| KBC Group NV | 0.00% | Add +3.7% | 2,723 | $241K |
| Birchview Capital, LP | 0.21% | No change | 2,700 | $239K |
| Lanark Financial, Inc. | 0.02% | — | 2,648 | $234K |
| Truist Financial Corp. | 0.00% | Add +3.2% | 2,612 | $231K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 2,610 | $231K |
| Atria Investments, Inc | 0.00% | New | 2,491 | $220K |
| Inceptionr LLC | 0.06% | New | 2,416 | $214K |
| Amalgamated Bank | 0.00% | Add +2.2% | 2,202 | $195K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -1.2% | 2,091 | $186K |
| Nisa Investment Advisors, LLC | 0.00% | Add +4.8% | 1,947 | $172K |
| AlphaQuest LLC | 0.02% | Add +1724.2% | 1,733 | $153K |
| PNC Financial Services Group, Inc. | 0.00% | Add +1.4% | 1,674 | $148K |
| Osaic Holdings, Inc. | 0.00% | Add +31.1% | 1,652 | $146K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 1,626 | $144K |
| Exchange Traded Concepts, LLC | 0.00% | Reduce -31.2% | 1,383 | $122K |
| Coldstream Capital Management Inc. | 0.00% | New | 1,144 | $101K |
| Covestor Ltd | 0.07% | Add +15.9% | 1,128 | $100K |
| Van Eck Associates Corp. | 0.00% | No change | 1,116 | $99K |
| CI Investments Inc. | 0.00% | Reduce -37.8% | 1,021 | $90K |
| BI Asset Management Fondsmaeglerselskab A/S | 0.00% | New | 988 | $87K |
| Headlands Technologies LLC | 0.01% | Add +25.0% | 936 | $83K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Add +1.8% | 869 | $77K |
| Compass Wealth Management LLC | 0.02% | No change | 750 | $66K |
| Vega Investment Solutions | 0.01% | New | 597 | $53K |
| Ostrum Asset Management | 0.00% | New | 597 | $53K |
| Leonteq Securities AG | 0.00% | Reduce -40.7% | 425 | $38K |
| Tortoise Investment Management, LLC | 0.00% | No change | 396 | $35K |
| GAMMA Investing LLC | 0.00% | Add +36.4% | 326 | $29K |
| Lindbrook Capital, LLC | 0.00% | Add +3.0% | 309 | $27K |
| Optiver Holding B.V. | 0.00% | New | 309 | $27K |
| Danske Bank A/S | 0.00% | No change | 300 | $27K |
| Parallel Advisors, LLC | 0.00% | Reduce -9.5% | 275 | $24K |
| Huntington National Bank | 0.00% | Reduce -16.6% | 247 | $22K |
| Picton Mahoney Asset Management | 0.00% | Add +442.5% | 217 | $20K |
| Asset Management One Co., Ltd. | 0.00% | Reduce -77.7% | 221 | $20K |
| Daiwa Securities Group Inc. | 0.00% | No change | 210 | $19K |
| Crowley Wealth Management, Inc. | 0.02% | No change | 200 | $18K |
| Harbour Investments, Inc. | 0.00% | No change | 200 | $18K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +17.3% | 190 | $17K |
| Bessemer Group Inc. | 0.00% | Reduce -32.5% | 160 | $14K |
| Signaturefd, LLC | 0.00% | Reduce -15.0% | 153 | $14K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -23.6% | 149 | $13K |
| True Wealth Design, LLC | 0.01% | Reduce -0.7% | 149 | $13K |
| Rise Advisors, LLC | 0.01% | Reduce -14.1% | 134 | $12K |
| UMB Bank, n.a. | 0.00% | No change | 127 | $11K |
| AdvisorNet Financial, Inc | 0.00% | No change | 119 | $11K |
| Arax Advisory Partners | 0.00% | Add +134.0% | 117 | $10K |
| Blue Trust, Inc. | 0.00% | No change | 113 | $10K |
| Parkside Financial Bank & Trust | 0.00% | Add +29.8% | 109 | $10K |
| Clearstead Trust, LLC | 0.00% | No change | 101 | $9K |
| TD Capital Management LLC | 0.00% | New | 100 | $9K |
| Farmers & Merchants Investments Inc. | 0.00% | No change | 100 | $9K |
| Truvestments Capital LLC | 0.00% | No change | 98 | $9K |
| Accent Capital Management, LLC | 0.00% | New | 80 | $7K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 80 | $7K |
| SVB Wealth LLC | 0.00% | New | 77 | $7K |
| Cullen/Frost Bankers, Inc. | 0.00% | No change | 70 | $6K |
| Global Financial Private Client, LLC | 0.00% | New | 66 | $6K |
| Sterling Capital Management LLC | 0.00% | Add +1.5% | 66 | $6K |
| Rothschild Investment LLC | 0.00% | No change | 65 | $6K |
| Farther Finance Advisors, LLC | 0.00% | Add +43.5% | 66 | $6K |
| Quent Capital, LLC | 0.00% | No change | 61 | $5K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 58 | $5K |
| Private Wealth Management Group, LLC | 0.00% | No change | 49 | $4K |
| Versant Capital Management, Inc | 0.00% | Reduce -35.6% | 47 | $4K |
| Allworth Financial LP | 0.00% | Add +235.7% | 47 | $4K |
| Highline Wealth Partners LLC | 0.00% | New | 42 | $4K |
| WPG Advisers, LLC | 0.00% | Add +21.9% | 39 | $3K |
| Clearstead Advisors, LLC | 0.00% | Reduce -39.7% | 38 | $3K |
| Principal Securities, Inc. | 0.00% | No change | 25 | $2K |
| CENTRAL TRUST Co | 0.00% | No change | 23 | $2K |
| First Horizon Advisors, Inc. | 0.00% | No change | 21 | $2K |
| Stephens Consulting, LLC | 0.00% | New | 20 | $2K |
| Wolff Wiese Magana LLC | 0.00% | No change | 19 | $2K |
| Assetmark, Inc. | 0.00% | Add +21.4% | 17 | $2K |
| Jones Financial Companies LLLP | 0.00% | New | 16 | $1K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +7.1% | 15 | $1K |
| Bayforest Capital Ltd | 0.00% | Reduce -99.5% | 13 | $1K |
| Riggs Asset Managment Co. Inc. | 0.00% | No change | 12 | $1K |
| Transamerica Financial Advisors, LLC | 0.00% | No change | 1 | $1K |
| SBI Securities Co., Ltd. | 0.00% | Add +100.0% | 10 | $885 |
| Cornerstone Planning Group LLC | 0.00% | New | 9 | $772 |
| Montag A & Associates Inc. | 0.00% | New | 9 | $763 |
| Bokf, NA | 0.00% | No change | 8 | $708 |
| Geneos Wealth Management Inc. | 0.00% | New | 8 | $708 |
| Amundi | 0.00% | New | 8 | $697 |
| Physician Wealth Advisors, Inc. | 0.00% | New | 7 | $620 |
| Brooklyn Investment Group | 0.00% | New | 7 | $620 |
| ORG Partners LLC | 0.00% | New | 7 | $601 |
| MAI Capital Management | 0.00% | New | 6 | $532 |
| SouthState Bank Corp | 0.00% | New | 5 | $443 |
| Wilmington Savings Fund Society, FSB | 0.00% | No change | 5 | $443 |
| Creative Financial Designs Inc. | 0.00% | New | 4 | $354 |
| NewEdge Advisors, LLC | 0.00% | No change | 4 | $354 |
| American Capital Advisory, LLC | 0.00% | New | 3 | $266 |
| Quadrant Capital Group LLC | 0.00% | No change | 3 | $266 |
| TD Private Client Wealth LLC | 0.00% | New | 2 | $177 |
| Larson Financial Group LLC | 0.00% | New | 2 | $177 |
| Innovative Advisory Group, LLC | 0.00% | No change | 1 | $89 |
| National Bank of Canada | 0.00% | New | 1 | $89 |
| TFC Financial Management, Inc. | 0.00% | New | 1 | $89 |
| Capital Advisors, Ltd. LLC | 0.00% | No change | 3 | $0 |
"% of holder's portfolio" is BPMC's weight in each manager's 13F, not the share of Blueprint Medicines Corp. the manager owns.