Blueprint MedicinesBPMC
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 356 institutions reported holding Blueprint Medicines Corp. (BPMC) in their 13F filings, up 3 from Q1 2025. 108 opened new positions and 105 sold out. The largest holders were Vanguard Group Inc. ($822.5M), BlackRock, Inc. ($784.3M) and Pentwater Capital Management LP ($499.9M). 8 famous investors held it, including George Soros (0.9% of Soros Fund Management's portfolio), Paul Tudor Jones (0.5% of Tudor Investment Corporation's portfolio) and Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio).
- Company
- Blueprint Medicines Corp.
- CUSIP
- 09627Y109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 108 | $3.0B |
| Exits | 105 | $917.8M |
All 13F filers, Q1 2025 → Q2 2025: 33,084,151 shares bought and 34,606,826 shares sold, net −1,522,675 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 356 holders
| Vanguard Group Inc. | 0.01% | Reduce -3.4% | 6,416,603 | $822.5M |
| BlackRock, Inc. | 0.01% | Reduce -8.8% | 6,118,428 | $784.3M |
| Pentwater Capital Management LP | 6.39% | New | 3,900,000 | $499.9M |
| HBK Investments L P | 8.28% | New | 3,200,924 | $410.3M |
| State Street Corp. | 0.01% | Reduce -16.9% | 2,230,980 | $286.0M |
| UBS Group AG | 0.06% | Add +913.5% | 2,167,028 | $277.8M |
| FIL Ltd | 0.19% | New | 1,759,500 | $225.5M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 6.28% | Add +11427.7% | 1,713,587 | $219.6M |
| Barclays PLC | 0.08% | Add +1101.4% | 1,556,918 | $199.6M |
| Geode Capital Management, LLC | 0.01% | Add +1.2% | 1,541,013 | $197.6M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -73.0% | 1,464,968 | $187.8M |
| Glazer Capital, LLC | 7.08% | New | 1,331,300 | $170.6M |
| Norges Bank | 0.02% | Add +78.3% | 1,074,936 | $137.8M |
| Beryl Capital Management LLC | 20.60% | New | 1,067,224 | $136.8M |
| Alpine Associates Management Inc. | 7.29% | New | 1,060,307 | $135.9M |
| Davidson Kempner Capital Management LP | 3.14% | New | 1,035,100 | $132.7M |
| Morgan Stanley | 0.01% | Add +81.3% | 1,031,170 | $132.2M |
| Macquarie Group Ltd. | 0.15% | Reduce -28.3% | 922,167 | $118.2M |
| Goldman Sachs Group Inc. | 0.02% | Reduce -3.8% | 891,287 | $114.2M |
| Syquant Capital Sas | 34.46% | New | 805,603 | $103.3M |
| Alliancebernstein L.P. | 0.03% | Reduce -36.0% | 765,387 | $98.1M |
| Magnetar Financial LLC | 0.47% | Add +15881.8% | 730,047 | $93.6M |
| Eventide Asset Management, LLC | 1.64% | Reduce -15.5% | 728,821 | $93.4M |
| Renaissance Technologies | 0.12% | New | 674,500 | $86.5M |
| Bank of America Corp. | 0.01% | Reduce -9.7% | 647,487 | $83.0M |
| Northern Trust Corp. | 0.01% | Reduce -3.5% | 568,924 | $72.9M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -6.4% | 561,159 | $71.9M |
| FMR LLC | 0.00% | Reduce -61.0% | 558,960 | $71.6M |
| Voloridge Investment Management, LLC | 0.26% | Add +5413.3% | 558,768 | $71.6M |
| Woodline Partners LP | 0.36% | Reduce -1.6% | 531,880 | $68.2M |
| Man Group plc | 0.15% | Reduce -0.7% | 516,258 | $66.2M |
| Invesco Ltd. | 0.01% | Reduce -48.1% | 511,091 | $65.5M |
| Balyasny Asset Management L.P. | 0.15% | Add +739.3% | 505,957 | $64.9M |
| Nuveen, LLC | 0.02% | Add +82.5% | 488,612 | $62.6M |
| Nexpoint Asset Management, L.P. | 5.87% | New | 476,742 | $61.1M |
| Tudor Investment Corporation | 0.45% | Add +2029.0% | 468,623 | $60.1M |
| Brown Advisory Inc. | 0.08% | Reduce -21.2% | 458,559 | $58.8M |
| First Trust Capital Management L.P. | 3.95% | New | 456,068 | $58.5M |
| Wellington Management Group LLP | 0.01% | Reduce -85.8% | 435,976 | $55.9M |
| JPMorgan Chase & Co. | 0.00% | Reduce -83.3% | 418,060 | $53.6M |
| Clearbridge Investments, LLC | 0.04% | Reduce -39.6% | 405,708 | $52.0M |
| LMR Partners LLP | 1.16% | Add +3603.4% | 395,857 | $50.7M |
| Quadrature Capital Ltd | 0.85% | New | 382,677 | $49.1M |
| Avoro Capital Advisors LLC | 0.84% | Reduce -90.3% | 375,000 | $48.1M |
| Readystate Asset Management LP | 3.18% | New | 329,831 | $42.3M |
| Whitebox Advisors LLC | 2.86% | New | 310,001 | $39.7M |
| TIG Advisors, LLC | 2.13% | New | 305,097 | $39.1M |
| Millennium Management | 0.04% | Reduce -57.2% | 295,879 | $37.9M |
| Slotnik Capital, LLC | 15.11% | New | 292,694 | $37.5M |
| Bellevue Group AG | 0.80% | New | 284,900 | $36.5M |
| Janus Henderson Group PLC | 0.02% | Add +835.4% | 268,928 | $34.5M |
| Cinctive Capital Management LP | 1.90% | Add +749.5% | 265,000 | $34.0M |
| Novo Holdings A/S | 2.40% | Add +15.8% | 264,956 | $34.0M |
| Polar Asset Management Partners Inc. | 1.13% | New | 262,964 | $33.7M |
| Affinity Asset Advisors, LLC | 4.94% | New | 250,000 | $32.0M |
| Soros Fund Management | 0.85% | New | 250,000 | $32.0M |
| KRYGER CAPITAL Ltd | 5.89% | New | 248,219 | $31.8M |
| Trium Capital LLP | 7.66% | New | 240,099 | $30.8M |
| Bank of New York Mellon Corp | 0.01% | Reduce -25.8% | 227,843 | $29.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Reduce -11.7% | 215,946 | $27.7M |
| Jane Street Group, LLC | 0.04% | Reduce -43.0% | 214,394 | $27.5M |
| Gabelli Funds LLC | 0.20% | New | 211,169 | $27.1M |
| Sand Grove Capital Management LLP | 13.62% | New | 211,124 | $27.1M |
| Highbridge Capital Management LLC | 3.79% | New | 189,822 | $24.3M |
| Deutsche Bank AG | 0.01% | Reduce -5.3% | 189,250 | $24.3M |
| Rock Springs Capital Management LP | 1.49% | Reduce -81.6% | 185,500 | $23.8M |
| Oddo BHF Asset Management Sas | 0.90% | New | 185,000 | $23.7M |
| Susquehanna International Group, LLP | 0.04% | Reduce -55.4% | 184,115 | $23.6M |
| GABELLI & Co INVESTMENT ADVISERS, INC. | 3.62% | New | 183,374 | $23.5M |
| Franklin Resources Inc. | 0.01% | Add +27.5% | 173,510 | $22.2M |
| Picton Mahoney Asset Management | 0.31% | Add +78241.0% | 170,000 | $21.8M |
| DAFNA Capital Management LLC | 6.06% | Add +10.8% | 168,763 | $21.6M |
| Nearwater Capital Markets, Ltd | 0.33% | New | 160,000 | $20.5M |
| Capula Management Ltd | 0.25% | New | 156,114 | $20.0M |
| Citigroup Inc. | 0.01% | Reduce -49.5% | 154,048 | $19.7M |
| Panagora Asset Management Inc. | 0.09% | Reduce -27.3% | 149,440 | $19.2M |
| Jump Financial, LLC | 0.24% | New | 147,325 | $18.9M |
| Susquehanna Portfolio Strategies, LLC | 0.38% | New | 135,057 | $17.3M |
| Squarepoint Ops LLC | 0.04% | Add +418.1% | 130,066 | $16.7M |
| Hudson Bay Capital Management LP | 0.12% | New | 129,398 | $16.6M |
| Baker Bros. Advisors LP | 0.16% | New | 125,538 | $16.1M |
| Swiss National Bank | 0.01% | Reduce -0.9% | 122,000 | $15.6M |
| Credit Industriel Et Commercial | 3.33% | New | 120,850 | $15.5M |
| Twin Securities, Inc. | 13.63% | New | 120,126 | $15.4M |
| Pictet Asset Management Holding SA | 0.02% | Reduce -87.5% | 119,817 | $15.4M |
| Verition Fund Management LLC | 0.09% | Add +591.3% | 118,988 | $15.3M |
| Water Island Capital LLC | 2.89% | New | 116,631 | $14.9M |
| Melqart Asset Management (UK) Ltd | 2.00% | New | 109,437 | $14.0M |
| Orion Investment Co | 4.82% | Reduce -2.7% | 106,134 | $13.6M |
| Voya Investment Management LLC | 0.02% | Reduce -57.6% | 102,552 | $13.1M |
| Rhumbline Advisers | 0.01% | Add +8.4% | 99,649 | $12.8M |
| Legal & General Group Plc | 0.00% | Add +3.7% | 99,224 | $12.7M |
| Harvest Management LLC | 5.91% | New | 95,000 | $12.2M |
| Groupe la Francaise | 0.20% | New | 94,150 | $12.1M |
| Equitec Proprietary Markets, LLC | 47.98% | New | 92,500 | $11.9M |
| AQR Capital Management | 0.01% | Reduce -37.6% | 92,469 | $11.9M |
| State of Wisconsin Investment Board | 0.03% | Add +39.5% | 89,373 | $11.5M |
| Versor Investments LP | 1.99% | New | 88,042 | $11.3M |
| California Public Employees Retirement System | 0.01% | Add +11.8% | 86,709 | $11.1M |
| Prudential Financial Inc. | 0.01% | Reduce -10.2% | 83,973 | $10.8M |
| AQR Arbitrage LLC | 0.38% | New | 80,179 | $10.3M |
| Eisler Capital Management Ltd. | 0.34% | New | 78,198 | $10.0M |
| TD Asset Management Inc | 0.01% | Reduce -72.9% | 77,100 | $9.9M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.02% | New | 75,000 | $9.6M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -54.5% | 74,708 | $9.6M |
| Oberweis Asset Management Inc./ | 0.40% | Reduce -3.3% | 72,500 | $9.3M |
| HRT Financial LP | 0.04% | New | 69,916 | $9.0M |
| Raymond James Financial Inc. | 0.00% | Reduce -65.7% | 66,461 | $8.5M |
| Qube Research & Technologies Ltd | 0.01% | Reduce -80.3% | 66,275 | $8.5M |
| Westchester Capital Management, LLC | 0.49% | New | 64,928 | $8.3M |
| Jain Global LLC | 0.13% | Add +132.2% | 64,130 | $8.2M |
| California State Teachers Retirement System | 0.01% | Add +9.1% | 63,898 | $8.2M |
| Hillsdale Investment Management Inc. | 0.30% | Add +20.2% | 63,000 | $8.1M |
| Rafferty Asset Management, LLC | 0.03% | Reduce -39.0% | 60,567 | $7.8M |
| Massachusetts Financial Services Co. | 0.00% | Reduce -77.7% | 60,349 | $7.7M |
| Prelude Capital Management, LLC | 0.75% | New | 60,154 | $7.7M |
| Chicago Capital Management, LLC | 19.35% | New | 60,000 | $7.7M |
| Alberta Investment Management Corp | 0.07% | New | 60,000 | $7.7M |
| CSS LLC | 1.43% | New | 59,886 | $7.7M |
| Simplex Trading, LLC | 0.19% | Add +1090.2% | 55,989 | $7.2M |
| Point72 Asia (Singapore) Pte. Ltd. | 1.26% | New | 55,365 | $7.1M |
| Carmignac Gestion | 0.11% | New | 54,676 | $7.0M |
| Abc Arbitrage SA | 0.77% | New | 52,650 | $6.7M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | New | 50,000 | $6.4M |
| Canada Pension Plan Investment Board | 0.01% | Add +8.6% | 49,400 | $6.3M |
| PFM Health Sciences, LP | 0.55% | Add +4.3% | 48,444 | $6.2M |
| Cubist Systematic Strategies, LLC | 0.06% | New | 46,602 | $6.0M |
| EFG Asset Management (North America) Corp. | 0.83% | Reduce -37.6% | 45,826 | $5.9M |
| Taconic Capital Advisors LP | 0.67% | New | 45,000 | $5.8M |
| Yakira Capital Management, Inc. | 2.11% | New | 44,325 | $5.7M |
| Governors Lane LP | 0.75% | New | 42,566 | $5.5M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Reduce -51.0% | 41,571 | $5.3M |
| FNY Investment Advisers, LLC | 2.28% | New | 41,060 | $5.3M |
| First Trust Advisors LP | 0.00% | Add +1151.0% | 39,783 | $5.1M |
| Axiom Investors LLC | 0.04% | Add +13.9% | 39,676 | $5.1M |
| MetLife Investment Management, LLC | 0.03% | Add +1.6% | 38,125 | $4.9M |
| Essex Investment Management Co. LLC | 0.85% | Reduce -12.6% | 36,291 | $4.7M |
| Wells Fargo & Company | 0.00% | Add +0.0% | 35,338 | $4.5M |
| PDT Partners, LLC | 0.25% | Add +462.0% | 34,271 | $4.4M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -79.8% | 34,201 | $4.4M |
| Waverly Advisors, LLC | 0.05% | Reduce -2.1% | 33,957 | $4.4M |
| NBW Capital LLC | 0.93% | Reduce -2.8% | 33,703 | $4.3M |
| Mutual of America Capital Management LLC | 0.05% | Reduce -2.8% | 33,547 | $4.3M |
| Bayesian Capital Management, LP | 0.67% | New | 33,300 | $4.3M |
| Creative Planning | 0.00% | Add +55.8% | 32,810 | $4.2M |
| Synovus Financial Corp. | 0.05% | Add +1.3% | 32,572 | $4.2M |
| Ensign Peak Advisors, Inc | 0.01% | Reduce -89.3% | 32,500 | $4.2M |
| Marshall Wace, LLP | 0.00% | Add +200.9% | 31,900 | $4.1M |
| Intech Investment Management LLC | 0.04% | Reduce -20.4% | 31,834 | $4.1M |
| Vestcor Inc | 0.12% | New | 31,565 | $4.0M |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 29,562 | $3.8M |
| Sei Investments Co. | 0.00% | Reduce -60.1% | 28,131 | $3.6M |
| Pathstone Holdings, LLC | 0.01% | Add +3.9% | 27,464 | $3.5M |
| DekaBank Deutsche Girozentrale | 0.01% | No change | 25,883 | $3.3M |
| HGC Investment Management Inc. | 0.90% | New | 25,298 | $3.2M |
| Citadel Advisors | 0.00% | Reduce -2.0% | 25,094 | $3.2M |
| Erste Asset Management GmbH | 0.03% | No change | 25,100 | $3.2M |
| Vazirani Asset Management LLC | 12.25% | New | 25,000 | $3.2M |
| State of New Jersey Common Pension Fund D | 0.01% | No change | 22,824 | $2.9M |
| American Century Companies Inc. | 0.00% | Reduce -97.4% | 22,770 | $2.9M |
| Frontier Capital Management Co. LLC | 0.03% | Reduce -49.5% | 21,687 | $2.8M |
| New York State Common Retirement Fund | 0.00% | Add +5.5% | 20,920 | $2.7M |
| Athos Capital Ltd | 3.98% | New | 20,000 | $2.6M |
| Moore Capital Management, LP | 0.06% | New | 20,000 | $2.6M |
| ExodusPoint Capital Management, LP | 0.03% | New | 19,351 | $2.5M |
| Dimensional Fund Advisors LP | 0.00% | Add +1.6% | 18,907 | $2.4M |
| Envestnet Asset Management Inc. | 0.00% | Reduce -52.8% | 18,816 | $2.4M |
| Arizona State Retirement System | 0.01% | Add +2.5% | 18,651 | $2.4M |
| BNP Paribas Financial Markets | 0.00% | Add +268.8% | 18,556 | $2.4M |
| Ameriprise Financial Inc. | 0.00% | Reduce -95.0% | 18,199 | $2.3M |
| ProShare Advisors LLC | 0.00% | Add +7.3% | 17,873 | $2.3M |
| Handelsbanken Fonder AB | 0.01% | Reduce -5.4% | 17,651 | $2.3M |
| Teacher Retirement System of Texas | 0.01% | Add +0.7% | 17,223 | $2.2M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.01% | Add +1.1% | 17,194 | $2.2M |
| Walleye Capital LLC | 0.02% | Reduce -60.1% | 16,830 | $2.2M |
| Torray Investment Partners LLC | 0.31% | Reduce -0.4% | 16,615 | $2.1M |
| Schonfeld Strategic Advisors LLC | 0.02% | Reduce -64.2% | 16,228 | $2.1M |
| Dana Investment Advisors, Inc. | 0.07% | Reduce -57.3% | 16,031 | $2.1M |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,172 | $1.9M |
| SCS Capital Management LLC | 0.02% | No change | 15,163 | $1.9M |
| Mint Tower Capital Management B.V. | 0.55% | New | 15,000 | $1.9M |
| ADAR1 Capital Management, LLC | 0.32% | New | 15,000 | $1.9M |
| Guggenheim Capital LLC | 0.02% | Add +5.8% | 14,624 | $1.9M |
| Martingale Asset Management L P | 0.05% | Reduce -5.8% | 14,592 | $1.9M |
| Police & Firemen's Retirement System of New Jersey | 0.02% | Add +6.2% | 14,423 | $1.8M |
| CANADA LIFE ASSURANCE Co | 0.00% | Add +86.1% | 14,186 | $1.8M |
| Weiss Asset Management LP | 0.03% | New | 13,873 | $1.8M |
| Oak Ridge Investments LLC | 0.13% | Reduce -5.1% | 13,808 | $1.8M |
| Profund Advisors LLC | 0.06% | Reduce -36.6% | 13,210 | $1.7M |
| China Universal Asset Management Co., Ltd. | 0.16% | Add +1.2% | 12,971 | $1.7M |
| FORA Capital, LLC | 0.18% | New | 12,589 | $1.6M |
| Landscape Capital Management, L.L.C. | 0.13% | New | 12,468 | $1.6M |
| Ieq Capital, LLC | 0.01% | Reduce -4.7% | 12,450 | $1.6M |
| S&co Inc. | 0.10% | Reduce -13.0% | 12,000 | $1.5M |
| Capital Fund Management S.A. | 0.02% | Reduce -87.1% | 11,820 | $1.5M |
| Victory Capital Management Inc. | 0.00% | Reduce -24.0% | 11,625 | $1.5M |
| Skandinaviska Enskilda Banken AB (publ) | 0.01% | New | 11,500 | $1.5M |
| Los Angeles Capital Management LLC | 0.01% | No change | 11,138 | $1.4M |
| Sagefield Capital LP | 0.17% | New | 9,600 | $1.2M |
| Greenland Capital Management LP | 0.16% | New | 9,562 | $1.2M |
| Gsa Capital Partners LLP | 0.09% | Add +158.9% | 9,548 | $1.2M |
| Diversified Trust Co. | 0.03% | Reduce -38.6% | 9,354 | $1.2M |
| Entropy Technologies, LP | 0.09% | New | 8,722 | $1.1M |
| William Blair Investment Management, LLC | 0.00% | Reduce -99.4% | 8,574 | $1.1M |
| STRS Ohio | 0.00% | Add +23.9% | 8,300 | $1.1M |
| Cibc World Markets Corp. | 0.01% | Reduce -44.1% | 7,888 | $1.0M |
| Mariner, LLC | 0.00% | Add +1.6% | 7,605 | $975K |
| BCK Capital Management LP | 0.85% | New | 7,600 | $974K |
| Fisher Asset Management | 0.00% | Reduce -97.6% | 7,459 | $956K |
| Pallas Capital Advisors LLC | 0.04% | Add +7.6% | 7,361 | $944K |
| Crestwood Advisors Group, LLC | 0.02% | Reduce -6.2% | 7,157 | $917K |
| Henshaw Capital LLC | 0.04% | Reduce -16.6% | 7,066 | $906K |
| GAMCO Investors | 0.01% | New | 7,000 | $897K |
| E Fund Management Co., Ltd. | 0.04% | Reduce -27.2% | 6,761 | $867K |
| Royal Bank of Canada | 0.00% | Reduce -75.0% | 6,712 | $861K |
| Tower Research Capital LLC (TRC) | 0.02% | Reduce -20.2% | 6,527 | $837K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,512 | $835K |
| Ameritas Investment Partners, Inc. | 0.03% | No change | 6,492 | $832K |
| Cetera Investment Advisers | 0.00% | Reduce -6.8% | 6,388 | $819K |
| LPL Financial LLC | 0.00% | Reduce -61.4% | 6,261 | $803K |
| NINE MASTS CAPITAL Ltd | 0.32% | New | 6,000 | $769K |
| Quantbot Technologies LP | 0.02% | New | 5,848 | $750K |
| Values First Advisors, Inc. | 0.40% | Add +12.9% | 5,685 | $729K |
| Advisors Asset Management, Inc. | 0.01% | Reduce -1.8% | 5,453 | $699K |
| Engineers Gate Manager LP | 0.01% | Reduce -78.1% | 5,400 | $692K |
| Cwm, LLC | 0.00% | Reduce -2.0% | 5,214 | $668K |
| Wolverine Asset Management LLC | 0.05% | New | 5,191 | $665K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Add +33.3% | 5,055 | $648K |
| Cerity Partners LLC | 0.00% | Add +8.8% | 5,035 | $645K |
| Rangeley Capital, LLC | 0.83% | New | 5,000 | $641K |
| BTG Pactual Asset Management US LLC | 0.09% | New | 5,000 | $641K |
| Xponance LLC | 0.01% | Reduce -1.0% | 4,971 | $637K |
| Kennedy Capital Management LLC | 0.01% | Add +4.6% | 4,836 | $620K |
| Knights of Columbus Asset Advisors LLC | 0.04% | Reduce -63.4% | 4,752 | $609K |
| Pitcairn Co. | 0.04% | Reduce -57.1% | 4,744 | $608K |
| Allspring Global Investments Holdings, LLC | 0.00% | Reduce -5.5% | 4,687 | $602K |
| Fieldview Capital Management, LLC | 0.09% | Reduce -83.0% | 4,673 | $599K |
| Principal Financial Group Inc. | 0.00% | Reduce -71.7% | 4,553 | $584K |
| Gilbert & Cook, Inc. | 0.08% | Add +1.9% | 4,441 | $569K |
| Intrust Bank NA | 0.05% | Add +23.2% | 4,382 | $562K |
| Bridgefront Capital, LLC | 0.15% | New | 4,276 | $548K |
| Bardin Hill Management Partners LP | 0.34% | New | 4,210 | $540K |
| O'shaughnessy Asset Management, LLC | 0.00% | Add +23.2% | 4,123 | $528K |
| Mackenzie Financial Corp. | 0.00% | Reduce -75.3% | 4,001 | $513K |
| Citizens Financial Group Inc. | 0.01% | Add +0.8% | 3,967 | $508K |
| Farther Finance Advisors, LLC | 0.01% | Add +5851.5% | 3,928 | $503K |
| Polymer Capital Management (US) LLC | 0.07% | New | 3,544 | $454K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +4.3% | 3,497 | $449K |
| Susquehanna Fundamental Investments, LLC | 0.01% | No change | 3,470 | $445K |
| HSBC Holdings PLC | 0.00% | Reduce -67.6% | 3,409 | $437K |
| Virtu Financial LLC | 0.02% | New | 3,035 | $389K |
| SG Americas Securities, LLC | 0.00% | Reduce -58.9% | 2,988 | $383K |
| Diametric Capital, LP | 0.19% | New | 2,777 | $356K |
| Birchview Capital, LP | 0.34% | No change | 2,700 | $346K |
| Natixis | 0.00% | New | 2,641 | $339K |
| Comerica Bank | 0.00% | Reduce -61.8% | 2,587 | $332K |
| Clear Harbor Asset Management, LLC | 0.02% | New | 2,581 | $331K |
| Steward Partners Investment Advisory, LLC | 0.00% | Reduce -2.2% | 2,552 | $327K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +19.3% | 2,495 | $320K |
| Neuberger Berman Group LLC | 0.00% | Reduce -96.4% | 2,421 | $310K |
| Amalgamated Bank | 0.00% | No change | 2,202 | $282K |
| PenderFund Capital Management Ltd. | 0.16% | New | 2,200 | $282K |
| Praxis Investment Management Inc. | 0.02% | New | 2,090 | $268K |
| PEAK6 LLC | 0.01% | Reduce -37.7% | 2,000 | $256K |
| Linden Thomas Advisory Services, LLC | 0.03% | New | 1,985 | $254K |
| Nisa Investment Advisors, LLC | 0.00% | Add +0.1% | 1,950 | $250K |
| CIBC Asset Management Inc | 0.00% | New | 1,928 | $247K |
| PNC Financial Services Group, Inc. | 0.00% | Add +13.5% | 1,900 | $244K |
| Two Sigma Securities, LLC | 0.03% | New | 1,894 | $243K |
| Abel Hall, LLC | 0.11% | New | 1,846 | $237K |
| KBC Group NV | 0.00% | Reduce -34.8% | 1,776 | $228K |
| R Squared Ltd | 0.12% | New | 1,766 | $226K |
| Commonwealth Equity Services, LLC | 0.00% | New | 1,698 | $218K |
| Merit Financial Group, LLC | 0.00% | New | 1,662 | $213K |
| Swiss Life Asset Management Ltd | 0.00% | New | 1,638 | $210K |
| GF Fund Management Co. LTD. | 0.00% | No change | 1,626 | $208K |
| AlphaQuest LLC | 0.02% | Reduce -6.3% | 1,623 | $208K |
| Quantinno Capital Management LP | 0.00% | New | 1,599 | $205K |
| DRW Securities, LLC | 0.01% | New | 1,593 | $204K |
| BIT Capital GmbH | 0.01% | Reduce -98.2% | 1,423 | $182K |
| Covestor Ltd | 0.10% | Add +21.0% | 1,365 | $175K |
| Lazard Asset Management LLC | 0.00% | Reduce -92.2% | 1,348 | $172K |
| US Bancorp \de | 0.00% | Reduce -85.5% | 1,203 | $154K |
| Bayforest Capital Ltd | 0.06% | Add +8453.9% | 1,112 | $143K |
| Van Eck Associates Corp. | 0.00% | Reduce -10.0% | 1,004 | $129K |
| Fifth Third Bancorp | 0.00% | Reduce -69.0% | 1,000 | $128K |
| CI Investments Inc. | 0.00% | Reduce -4.9% | 971 | $124K |
| Essential Partners LLC | 0.04% | — | 878 | $113K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -2.2% | 850 | $109K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Reduce -99.2% | 584 | $75K |
| Optiver Holding B.V. | 0.00% | Add +33.3% | 412 | $53K |
| Tortoise Investment Management, LLC | 0.00% | Add +0.3% | 397 | $51K |
| Lanark Financial, Inc. | 0.00% | Reduce -86.6% | 355 | $45K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +65.8% | 315 | $40K |
| Vega Investment Solutions | 0.01% | Reduce -48.1% | 310 | $40K |
| Danske Bank A/S | 0.00% | No change | 300 | $38K |
| Parallel Advisors, LLC | 0.00% | No change | 275 | $35K |
| Osaic Holdings, Inc. | 0.00% | Reduce -83.2% | 278 | $35K |
| Truvestments Capital LLC | 0.01% | Add +165.3% | 260 | $33K |
| GAMMA Investing LLC | 0.00% | Reduce -23.3% | 250 | $32K |
| Elevation Point Wealth Partners, LLC | 0.00% | New | 231 | $30K |
| Daiwa Securities Group Inc. | 0.00% | Add +7.1% | 225 | $29K |
| Huntington National Bank | 0.00% | Reduce -14.6% | 211 | $27K |
| Crowley Wealth Management, Inc. | 0.02% | No change | 200 | $26K |
| Harbour Investments, Inc. | 0.00% | No change | 200 | $26K |
| Headlands Technologies LLC | 0.00% | Reduce -80.2% | 185 | $24K |
| True Wealth Design, LLC | 0.01% | Add +23.5% | 184 | $24K |
| Caitong International Asset Management Co., Ltd | 0.02% | New | 180 | $23K |
| Bessemer Group Inc. | 0.00% | Add +8.8% | 174 | $22K |
| Signaturefd, LLC | 0.00% | Add +3.9% | 159 | $20K |
| Global Retirement Partners, LLC | 0.00% | — | 157 | $20K |
| Sterling Capital Management LLC | 0.00% | Add +137.9% | 157 | $20K |
| UMB Bank, n.a. | 0.00% | Add +6.3% | 135 | $17K |
| Rise Advisors, LLC | 0.01% | No change | 134 | $17K |
| Rothschild Investment LLC | 0.00% | Add +100.0% | 130 | $17K |
| AdvisorNet Financial, Inc | 0.00% | Add +6.7% | 127 | $16K |
| Clearstead Advisors, LLC | 0.00% | Add +218.4% | 121 | $16K |
| Allworth Financial LP | 0.00% | Add +157.4% | 121 | $16K |
| Versant Capital Management, Inc | 0.00% | Add +119.2% | 103 | $13K |
| Clearstead Trust, LLC | 0.00% | No change | 101 | $13K |
| Boreal Capital Management LLC | 0.01% | — | 100 | $13K |
| TD Capital Management LLC | 0.00% | No change | 100 | $13K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -36.9% | 94 | $12K |
| Accent Capital Management, LLC | 0.00% | No change | 80 | $10K |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 80 | $10K |
| Cullen/Frost Bankers, Inc. | 0.00% | No change | 70 | $9K |
| Arax Advisory Partners | 0.00% | Reduce -47.9% | 61 | $8K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 58 | $7K |
| Parkside Financial Bank & Trust | 0.00% | Reduce -53.2% | 51 | $7K |
| IFP Advisors, Inc | 0.00% | New | 50 | $6K |
| Private Wealth Management Group, LLC | 0.00% | No change | 49 | $6K |
| WPG Advisers, LLC | 0.00% | Add +15.4% | 45 | $6K |
| Highline Wealth Partners LLC | 0.00% | No change | 42 | $5K |
| Assetmark, Inc. | 0.00% | Add +135.3% | 40 | $5K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +106.7% | 31 | $4K |
| Brooklyn Investment Group | 0.00% | Add +242.9% | 24 | $3K |
| CENTRAL TRUST Co | 0.00% | No change | 23 | $3K |
| Geneos Wealth Management Inc. | 0.00% | Add +187.5% | 23 | $3K |
| Riggs Asset Managment Co. Inc. | 0.00% | Add +83.3% | 22 | $3K |
| First Horizon Advisors, Inc. | 0.00% | No change | 21 | $3K |
| Wolff Wiese Magana LLC | 0.00% | No change | 19 | $2K |
| Meeder Asset Management Inc. | 0.00% | New | 18 | $2K |
| Leonteq Securities AG | 0.00% | Reduce -97.2% | 12 | $2K |
| ORG Partners LLC | 0.00% | Add +57.1% | 11 | $1K |
| Physician Wealth Advisors, Inc. | 0.00% | Add +28.6% | 9 | $1K |
| MAI Capital Management | 0.00% | Add +50.0% | 9 | $1K |
| Jones Financial Companies LLLP | 0.00% | Reduce -43.8% | 9 | $1K |
| Bokf, NA | 0.00% | No change | 8 | $1K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -50.0% | 5 | $641 |
| CIBC Private Wealth Group LLC | 0.00% | New | 4 | $513 |
| NewEdge Advisors, LLC | 0.00% | No change | 4 | $513 |
| Larson Financial Group LLC | 0.00% | Add +50.0% | 3 | $385 |
| Innovative Advisory Group, LLC | 0.00% | No change | 1 | $128 |
| Concord Wealth Partners | 0.00% | New | 1 | $128 |
| Transamerica Financial Advisors, LLC | 0.00% | No change | 1 | $78 |
| Capital Advisors, Ltd. LLC | 0.00% | No change | 3 | $0 |
"% of holder's portfolio" is BPMC's weight in each manager's 13F, not the share of Blueprint Medicines Corp. the manager owns.