Cabaletta BioCABA

13F holders, Q4 2025 (December 31)
95holders +20
29new positions
8sold out
4famous investors
$2.19avg. 13F price*

At the end of Q4 2025, 95 institutions reported holding Cabaletta Bio Inc. (CABA) in their 13F filings, up 20 from Q3 2025. 29 opened new positions and 8 sold out. The largest holders were T. Rowe Price Investment Management, Inc. ($21.6M), Bain Capital Life Sciences Investors, LLC ($21.2M) and Jennison Associates LLC ($19.5M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).

Company
Cabaletta Bio Inc.
CUSIP
12674W109
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q1 2024: 159Q1 2024Q2 2024: 142Q2 2024Q3 2024: 120Q3 2024Q4 2024: 108Q4 2024Q1 2025: 92Q1 2025Q2 2025: 86Q2 2025Q3 2025: 75Q3 2025Q4 2025: 95Q4 2025Q1 2026: 108Q1 2026Q2 2026: 139Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions29$10.2M
Exits8$8.7M

All 13F filers, Q3 2025 → Q4 2025: 14,440,617 shares bought and 7,866,487 shares sold, net +6,574,130 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 95 holders

T. Rowe Price Investment Management, Inc. 0.01% Add +17.9% 9,858,257 $21.6M
Bain Capital Life Sciences Investors, LLC 1.63% No change 9,677,125 $21.2M
Jennison Associates LLC 0.01% Add +4.8% 8,905,699 $19.5M
Adage Capital Partners Gp, L.L.C. 0.03% No change 8,829,758 $19.3M
Vanguard Group Inc. 0.00% Add +5.5% 4,419,458 $9.7M
Cormorant Asset Management, LP 0.55% Reduce -12.0% 4,400,000 $9.6M
Millennium Management 0.00% Add +298.5% 2,736,912 $6.0M
BlackRock, Inc. 0.00% Add +43.7% 2,328,470 $5.1M
Superstring Capital Management LP 2.64% Add +45.9% 2,253,550 $4.9M
Two Sigma Investments, LP 0.01% Add +291.1% 1,839,799 $4.0M
Renaissance Technologies 0.01% Add +13.7% 1,522,583 $3.3M
Morgan Stanley 0.00% Reduce -8.9% 1,343,708 $2.9M
Woodline Partners LP 0.01% Reduce -41.5% 1,250,242 $2.7M
Schonfeld Strategic Advisors LLC 0.01% Add +15.3% 1,204,070 $2.6M
T. Rowe Price Associates Inc. 0.00% Reduce -15.5% 1,093,959 $2.4M
Geode Capital Management, LLC 0.00% Add +18.0% 1,085,816 $2.4M
Marshall Wace, LLP 0.00% Reduce -27.7% 959,076 $2.1M
Opaleye Management Inc. 0.26% Add +11.3% 900,000 $2.0M
Ikarian Capital, LLC 0.26% New 900,000 $2.0M
Schroder Investment Management Group 0.00% New 756,637 $1.6M
Two Sigma Advisers, LP 0.00% Add +122.9% 737,900 $1.6M
Burkehill Global Management, LP 0.11% No change 700,000 $1.5M
Jane Street Group, LLC 0.00% Add +532.6% 662,149 $1.5M
Ensign Peak Advisors, Inc 0.00% New 550,000 $1.2M
KVP Capital Advisors, LP 1.14% — 505,431 $1.1M
Dimensional Fund Advisors LP 0.00% New 452,039 $990K
Raiffeisen Bank International AG 0.01% Add +28.6% 450,000 $968K
Goldman Sachs Group Inc. 0.00% Add +58.0% 430,674 $943K
State Street Corp. 0.00% Add +12.9% 425,478 $932K
UBS Group AG 0.00% Add +2.6% 415,677 $910K
683 Capital Management, LLC 0.07% New 388,562 $851K
Almitas Capital LLC 0.19% No change 387,491 $849K
Qube Research & Technologies Ltd 0.00% Add +271.5% 331,225 $725K
Gsa Capital Partners LLP 0.06% New 303,992 $666K
Boothbay Fund Management, LLC 0.01% New 243,445 $533K
Northern Trust Corp. 0.00% Add +5.0% 238,442 $522K
Barclays PLC 0.00% Add +7058.5% 220,696 $483K
Invesco Ltd. 0.00% Add +54.1% 189,195 $414K
Stonepine Capital Management, LLC 0.30% New 171,100 $375K
XTX Topco Ltd 0.01% Reduce -45.3% 155,387 $340K
Graham Capital Management, L.P. 0.02% New 151,451 $332K
Squarepoint Ops LLC 0.00% Add +1156.3% 149,094 $327K
Hudson Bay Capital Management LP 0.00% New 138,729 $304K
Susquehanna International Group, LLP 0.00% Reduce -62.8% 138,281 $303K
Bridgeway Capital Management, LLC 0.01% Add +36.6% 130,675 $286K
OMERS ADMINISTRATION Corp 0.00% New 95,400 $209K
Letko, Brosseau & Associates Inc. 0.00% New 90,475 $198K
TD Asset Management Inc 0.00% No change 88,600 $194K
Citigroup Inc. 0.00% Add +20858.5% 73,774 $162K
Dynamic Technology Lab Private Ltd 0.03% New 66,789 $146K
Quadrature Capital Ltd 0.00% Add +54.7% 66,377 $145K
American Century Companies Inc. 0.00% Add +388.5% 58,777 $129K
Point72 Asset Management 0.00% New 56,648 $124K
Matauro, LLC 0.02% New 55,108 $121K
Bank of New York Mellon Corp 0.00% Add +13.1% 54,047 $118K
Balyasny Asset Management L.P. 0.00% New 51,552 $113K
Charles Schwab Investment Management Inc. 0.00% No change 50,824 $111K
Jefferies Financial Group Inc. 0.00% Reduce -5.0% 45,125 $99K
LPL Financial LLC 0.00% New 42,615 $93K
Lighthouse Investment Partners, LLC 0.00% New 38,880 $85K
Citadel Advisors 0.00% Reduce -95.3% 33,502 $73K
SG Americas Securities, LLC 0.00% Add +44.0% 30,629 $67K
Tower Research Capital LLC (TRC) 0.00% Add +594.9% 30,345 $66K
Fred Alger Management, LLC 0.00% Reduce -53.1% 28,021 $61K
Mercer Global Advisors Inc. 0.00% New 26,510 $58K
Callan Family Office, LLC 0.00% New 22,575 $49K
Vanguard Personalized Indexing Management, LLC 0.00% Add +1.1% 22,384 $49K
Jones Financial Companies LLLP 0.00% Add +3.3% 20,660 $45K
Clear Harbor Asset Management, LLC 0.00% New 19,500 $43K
ANTIPODES PARTNERS Ltd 0.00% New 17,187 $38K
China Universal Asset Management Co., Ltd. 0.00% New 15,686 $34K
CRA Financial Services, LLC 0.00% No change 15,000 $33K
Private Advisor Group, LLC 0.00% New 14,725 $32K
Bank of America Corp. 0.00% Reduce -94.6% 14,392 $32K
FMR LLC 0.00% Reduce -7.3% 13,045 $29K
Manufacturers Life Insurance Company, The 0.00% Reduce -0.6% 13,011 $28K
HB Wealth Management, LLC 0.00% New 10,000 $22K
JPMorgan Chase & Co. 0.00% Reduce -98.2% 9,805 $21K
Mirae Asset Global Investments Co., Ltd. 0.00% New 4,678 $10K
PNC Financial Services Group, Inc. 0.00% Add +666.7% 4,600 $10K
Canada Pension Plan Investment Board 0.00% New 3,500 $8K
Wells Fargo & Company 0.00% Reduce -33.3% 2,000 $4K
GF Fund Management Co. LTD. 0.00% New 1,891 $4K
BNP Paribas Financial Markets 0.00% Reduce -10.4% 1,640 $4K
Flagship Harbor Advisors, LLC 0.00% New 1,000 $2K
Russell Investments Group, Ltd. 0.00% No change 939 $2K
Nisa Investment Advisors, LLC 0.00% No change 811 $2K
Truvestments Capital LLC 0.00% No change 680 $1K
Federation des caisses Desjardins du Quebec 0.00% No change 340 $745
SBI Securities Co., Ltd. 0.00% Reduce -30.7% 316 $692
Northwestern Mutual Wealth Management Co. 0.00% Add +2900.0% 60 $131
Optiver Holding B.V. 0.00% No change 24 $53
Arax Advisory Partners 0.00% No change 10 $22
Royal Bank of Canada 0.00% Reduce -99.9% 123 $0
Covestor Ltd 0.00% No change 34 $0

"% of holder's portfolio" is CABA's weight in each manager's 13F, not the share of Cabaletta Bio Inc. the manager owns.