Cabaletta BioCABA
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 95 institutions reported holding Cabaletta Bio Inc. (CABA) in their 13F filings, up 20 from Q3 2025. 29 opened new positions and 8 sold out. The largest holders were T. Rowe Price Investment Management, Inc. ($21.6M), Bain Capital Life Sciences Investors, LLC ($21.2M) and Jennison Associates LLC ($19.5M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Cabaletta Bio Inc.
- CUSIP
- 12674W109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 29 | $10.2M |
| Exits | 8 | $8.7M |
All 13F filers, Q3 2025 → Q4 2025: 14,440,617 shares bought and 7,866,487 shares sold, net +6,574,130 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 95 holders
| T. Rowe Price Investment Management, Inc. | 0.01% | Add +17.9% | 9,858,257 | $21.6M |
| Bain Capital Life Sciences Investors, LLC | 1.63% | No change | 9,677,125 | $21.2M |
| Jennison Associates LLC | 0.01% | Add +4.8% | 8,905,699 | $19.5M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | No change | 8,829,758 | $19.3M |
| Vanguard Group Inc. | 0.00% | Add +5.5% | 4,419,458 | $9.7M |
| Cormorant Asset Management, LP | 0.55% | Reduce -12.0% | 4,400,000 | $9.6M |
| Millennium Management | 0.00% | Add +298.5% | 2,736,912 | $6.0M |
| BlackRock, Inc. | 0.00% | Add +43.7% | 2,328,470 | $5.1M |
| Superstring Capital Management LP | 2.64% | Add +45.9% | 2,253,550 | $4.9M |
| Two Sigma Investments, LP | 0.01% | Add +291.1% | 1,839,799 | $4.0M |
| Renaissance Technologies | 0.01% | Add +13.7% | 1,522,583 | $3.3M |
| Morgan Stanley | 0.00% | Reduce -8.9% | 1,343,708 | $2.9M |
| Woodline Partners LP | 0.01% | Reduce -41.5% | 1,250,242 | $2.7M |
| Schonfeld Strategic Advisors LLC | 0.01% | Add +15.3% | 1,204,070 | $2.6M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -15.5% | 1,093,959 | $2.4M |
| Geode Capital Management, LLC | 0.00% | Add +18.0% | 1,085,816 | $2.4M |
| Marshall Wace, LLP | 0.00% | Reduce -27.7% | 959,076 | $2.1M |
| Opaleye Management Inc. | 0.26% | Add +11.3% | 900,000 | $2.0M |
| Ikarian Capital, LLC | 0.26% | New | 900,000 | $2.0M |
| Schroder Investment Management Group | 0.00% | New | 756,637 | $1.6M |
| Two Sigma Advisers, LP | 0.00% | Add +122.9% | 737,900 | $1.6M |
| Burkehill Global Management, LP | 0.11% | No change | 700,000 | $1.5M |
| Jane Street Group, LLC | 0.00% | Add +532.6% | 662,149 | $1.5M |
| Ensign Peak Advisors, Inc | 0.00% | New | 550,000 | $1.2M |
| KVP Capital Advisors, LP | 1.14% | — | 505,431 | $1.1M |
| Dimensional Fund Advisors LP | 0.00% | New | 452,039 | $990K |
| Raiffeisen Bank International AG | 0.01% | Add +28.6% | 450,000 | $968K |
| Goldman Sachs Group Inc. | 0.00% | Add +58.0% | 430,674 | $943K |
| State Street Corp. | 0.00% | Add +12.9% | 425,478 | $932K |
| UBS Group AG | 0.00% | Add +2.6% | 415,677 | $910K |
| 683 Capital Management, LLC | 0.07% | New | 388,562 | $851K |
| Almitas Capital LLC | 0.19% | No change | 387,491 | $849K |
| Qube Research & Technologies Ltd | 0.00% | Add +271.5% | 331,225 | $725K |
| Gsa Capital Partners LLP | 0.06% | New | 303,992 | $666K |
| Boothbay Fund Management, LLC | 0.01% | New | 243,445 | $533K |
| Northern Trust Corp. | 0.00% | Add +5.0% | 238,442 | $522K |
| Barclays PLC | 0.00% | Add +7058.5% | 220,696 | $483K |
| Invesco Ltd. | 0.00% | Add +54.1% | 189,195 | $414K |
| Stonepine Capital Management, LLC | 0.30% | New | 171,100 | $375K |
| XTX Topco Ltd | 0.01% | Reduce -45.3% | 155,387 | $340K |
| Graham Capital Management, L.P. | 0.02% | New | 151,451 | $332K |
| Squarepoint Ops LLC | 0.00% | Add +1156.3% | 149,094 | $327K |
| Hudson Bay Capital Management LP | 0.00% | New | 138,729 | $304K |
| Susquehanna International Group, LLP | 0.00% | Reduce -62.8% | 138,281 | $303K |
| Bridgeway Capital Management, LLC | 0.01% | Add +36.6% | 130,675 | $286K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 95,400 | $209K |
| Letko, Brosseau & Associates Inc. | 0.00% | New | 90,475 | $198K |
| TD Asset Management Inc | 0.00% | No change | 88,600 | $194K |
| Citigroup Inc. | 0.00% | Add +20858.5% | 73,774 | $162K |
| Dynamic Technology Lab Private Ltd | 0.03% | New | 66,789 | $146K |
| Quadrature Capital Ltd | 0.00% | Add +54.7% | 66,377 | $145K |
| American Century Companies Inc. | 0.00% | Add +388.5% | 58,777 | $129K |
| Point72 Asset Management | 0.00% | New | 56,648 | $124K |
| Matauro, LLC | 0.02% | New | 55,108 | $121K |
| Bank of New York Mellon Corp | 0.00% | Add +13.1% | 54,047 | $118K |
| Balyasny Asset Management L.P. | 0.00% | New | 51,552 | $113K |
| Charles Schwab Investment Management Inc. | 0.00% | No change | 50,824 | $111K |
| Jefferies Financial Group Inc. | 0.00% | Reduce -5.0% | 45,125 | $99K |
| LPL Financial LLC | 0.00% | New | 42,615 | $93K |
| Lighthouse Investment Partners, LLC | 0.00% | New | 38,880 | $85K |
| Citadel Advisors | 0.00% | Reduce -95.3% | 33,502 | $73K |
| SG Americas Securities, LLC | 0.00% | Add +44.0% | 30,629 | $67K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +594.9% | 30,345 | $66K |
| Fred Alger Management, LLC | 0.00% | Reduce -53.1% | 28,021 | $61K |
| Mercer Global Advisors Inc. | 0.00% | New | 26,510 | $58K |
| Callan Family Office, LLC | 0.00% | New | 22,575 | $49K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +1.1% | 22,384 | $49K |
| Jones Financial Companies LLLP | 0.00% | Add +3.3% | 20,660 | $45K |
| Clear Harbor Asset Management, LLC | 0.00% | New | 19,500 | $43K |
| ANTIPODES PARTNERS Ltd | 0.00% | New | 17,187 | $38K |
| China Universal Asset Management Co., Ltd. | 0.00% | New | 15,686 | $34K |
| CRA Financial Services, LLC | 0.00% | No change | 15,000 | $33K |
| Private Advisor Group, LLC | 0.00% | New | 14,725 | $32K |
| Bank of America Corp. | 0.00% | Reduce -94.6% | 14,392 | $32K |
| FMR LLC | 0.00% | Reduce -7.3% | 13,045 | $29K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -0.6% | 13,011 | $28K |
| HB Wealth Management, LLC | 0.00% | New | 10,000 | $22K |
| JPMorgan Chase & Co. | 0.00% | Reduce -98.2% | 9,805 | $21K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | New | 4,678 | $10K |
| PNC Financial Services Group, Inc. | 0.00% | Add +666.7% | 4,600 | $10K |
| Canada Pension Plan Investment Board | 0.00% | New | 3,500 | $8K |
| Wells Fargo & Company | 0.00% | Reduce -33.3% | 2,000 | $4K |
| GF Fund Management Co. LTD. | 0.00% | New | 1,891 | $4K |
| BNP Paribas Financial Markets | 0.00% | Reduce -10.4% | 1,640 | $4K |
| Flagship Harbor Advisors, LLC | 0.00% | New | 1,000 | $2K |
| Russell Investments Group, Ltd. | 0.00% | No change | 939 | $2K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 811 | $2K |
| Truvestments Capital LLC | 0.00% | No change | 680 | $1K |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 340 | $745 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -30.7% | 316 | $692 |
| Northwestern Mutual Wealth Management Co. | 0.00% | Add +2900.0% | 60 | $131 |
| Optiver Holding B.V. | 0.00% | No change | 24 | $53 |
| Arax Advisory Partners | 0.00% | No change | 10 | $22 |
| Royal Bank of Canada | 0.00% | Reduce -99.9% | 123 | $0 |
| Covestor Ltd | 0.00% | No change | 34 | $0 |
"% of holder's portfolio" is CABA's weight in each manager's 13F, not the share of Cabaletta Bio Inc. the manager owns.