Crescent BiopharmaCBIO

13F holders, Q1 2026 (March 31)
60holders +4
14new positions
11sold out
3famous investors
$18.37avg. 13F price*

At the end of Q1 2026, 60 institutions reported holding Crescent Biopharma Inc. (CBIO) in their 13F filings, up 4 from Q4 2025. 14 opened new positions and 11 sold out. The largest holders were FMR LLC ($75.9M), BVF Inc. ($50.5M) and Fairmount Funds Management LLC ($50.5M). 3 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Crescent Biopharma Inc.
CUSIP
G2545C104
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080 Q2 2025: 30Q2 2025Q3 2025: 41Q3 2025Q4 2025: 56Q4 2025Q1 2026: 60Q1 2026Q2 2026: 80Q2 2026

Total Exit/New Position Q4 2025 → Q1 2026

InstitutionsTotal Value
New Positions14$11.7M
Exits11$15.8M

All 13F filers, Q4 2025 → Q1 2026: 3,445,474 shares bought and 2,337,919 shares sold, net +1,107,555 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 60 holders

FMR LLC 0.00% No change 4,133,514 $75.9M
BVF Inc. 1.61% No change 2,748,763 $50.5M
Fairmount Funds Management LLC 3.65% No change 2,747,866 $50.5M
Venrock Adviser, LLC 1.46% No change 2,133,576 $39.2M
FCPM III Services B.V. 4.27% No change 1,677,852 $30.8M
Balyasny Asset Management L.P. 0.06% Add +1251.7% 1,510,033 $27.7M
Vestal Point Capital, LP 0.77% No change 1,500,000 $27.6M
Opaleye Management Inc. 3.18% Add +11.4% 1,312,615 $24.1M
Tang Capital Management LLC 1.08% Add +33.0% 1,160,000 $21.3M
Vanguard Capital Management LLC 0.00% — 801,395 $14.7M
Logos Global Management LP 0.46% Reduce -19.6% 482,500 $8.9M
Deep Track Capital, LP 0.17% No change 453,686 $8.3M
NEXTBio Capital Management LP 3.18% No change 372,856 $6.8M
RTW Investments, LP 0.07% No change 372,856 $6.8M
Millennium Management 0.00% Add +422.9% 323,553 $5.9M
T. Rowe Price Associates Inc. 0.00% Reduce -10.2% 303,551 $5.6M
Point72 Asset Management 0.01% No change 300,000 $5.5M
Alyeska Investment Group, L.P. 0.01% No change 264,000 $4.8M
Goldman Sachs Group Inc. 0.00% Add +805.0% 228,475 $4.2M
Susquehanna International Group, LLP 0.01% Add +274.5% 213,635 $3.9M
Perceptive Advisors LLC 0.08% Reduce -54.4% 206,942 $3.8M
Marshall Wace, LLP 0.00% Add +819.9% 200,780 $3.7M
Exome Asset Management LLC 1.66% New 153,191 $2.8M
Jennison Associates LLC 0.00% New 152,974 $2.8M
Silverarc Capital Management, LLC 0.28% New 130,500 $2.4M
Two Sigma Investments, LP 0.00% Reduce -7.5% 115,828 $2.1M
BlackRock, Inc. 0.00% Add +6.0% 115,725 $2.1M
Geode Capital Management, LLC 0.00% Add +14.4% 104,221 $1.9M
Hudson Bay Capital Management LP 0.01% New 88,867 $1.6M
Stonepine Capital Management, LLC 1.37% Reduce -3.1% 85,000 $1.6M
UBS Group AG 0.00% Add +1060.8% 82,706 $1.5M
Burkehill Global Management, LP 0.07% No change 74,000 $1.4M
Woodline Partners LP 0.01% No change 74,000 $1.4M
ADAR1 Capital Management, LLC 0.06% Reduce -91.7% 50,273 $924K
Vanguard Fiduciary Trust Co. 0.00% — 49,423 $908K
State Street Corp. 0.00% Add +49.0% 39,067 $718K
JPMorgan Chase & Co. 0.00% Add +75.7% 41,004 $681K
Barclays PLC 0.00% New 30,189 $555K
Bank of America Corp. 0.00% Add +425.3% 29,277 $538K
Moore Capital Management, LP 0.02% No change 25,000 $459K
Lighthouse Investment Partners, LLC 0.02% New 25,000 $459K
Manufacturers Life Insurance Company, The 0.00% No change 24,903 $457K
Renaissance Technologies 0.00% Reduce -48.0% 24,262 $446K
Citigroup Inc. 0.00% Add +3137.4% 20,169 $371K
Brevan Howard Capital Management LP 0.00% New 19,530 $359K
Morgan Stanley 0.00% Reduce -32.5% 18,577 $341K
OMERS ADMINISTRATION Corp 0.00% Add +53.5% 17,800 $327K
Northern Trust Corp. 0.00% No change 17,229 $316K
BNP Paribas Financial Markets 0.00% Add +337.8% 15,694 $288K
Algert Global LLC 0.00% New 13,806 $254K
Verdad Advisers, LP 0.26% New 12,748 $234K
Cannon Global Investment Management, LLC 0.46% New 10,200 $187K
Vanguard Global Advisers, LLC 0.00% — 3,469 $64K
Parallel Advisors, LLC 0.00% New 264 $5K
Allworth Financial LP 0.00% New 161 $3K
SBI Securities Co., Ltd. 0.00% No change 68 $1K
Royal Bank of Canada 0.00% Add +155.0% 51 $1K
Fortitude Family Office, LLC 0.00% New 40 $735
Osaic Holdings, Inc. 0.00% No change 26 $477
Caitong International Asset Management Co., Ltd 0.00% New 4 $73

"% of holder's portfolio" is CBIO's weight in each manager's 13F, not the share of Crescent Biopharma Inc. the manager owns.