Caribou BiosciencesCRBU
13F holders, Q3 2025 (September 30)At the end of Q3 2025, 117 institutions reported holding Caribou Biosciences Inc. (CRBU) in their 13F filings, down 12 from Q2 2025. 15 opened new positions and 28 sold out. The largest holders were Pfizer Inc ($10.9M), Vanguard Group Inc. ($9.8M) and Millennium Management ($7.5M). 6 famous investors held it, including Lee Ainslie (0.0% of Maverick Capital's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Caribou Biosciences Inc.
- CUSIP
- 142038108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 15 | $1.2M |
| Exits | 28 | $1.7M |
All 13F filers, Q2 2025 → Q3 2025: 4,131,000 shares bought and 7,765,262 shares sold, net −3,634,262 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 117 holders
| Pfizer Inc | 2.50% | No change | 4,690,431 | $10.9M |
| Vanguard Group Inc. | 0.00% | Add +3.4% | 4,226,926 | $9.8M |
| Millennium Management | 0.01% | Add +107.4% | 3,216,535 | $7.5M |
| Kynam Capital Management, LP | 0.53% | No change | 3,067,774 | $7.1M |
| BlackRock, Inc. | 0.00% | Reduce -22.5% | 1,459,320 | $3.4M |
| Aberdeen Group plc | 0.01% | Add +54.7% | 1,388,905 | $3.2M |
| PFM Health Sciences, LP | 0.27% | No change | 1,358,831 | $3.2M |
| Two Sigma Advisers, LP | 0.01% | Reduce -15.2% | 1,227,400 | $2.9M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -7.4% | 1,210,310 | $2.8M |
| Bank of America Corp. | 0.00% | Add +32.8% | 1,074,442 | $2.5M |
| Geode Capital Management, LLC | 0.00% | Add +0.4% | 985,126 | $2.3M |
| Two Sigma Investments, LP | 0.00% | Reduce -15.6% | 783,590 | $1.8M |
| Renaissance Technologies | 0.00% | Add +46.7% | 780,421 | $1.8M |
| Pale Fire Capital SE | 0.20% | No change | 775,055 | $1.8M |
| FMR LLC | 0.00% | Reduce -0.1% | 729,002 | $1.7M |
| Maverick Capital | 0.02% | No change | 652,542 | $1.5M |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -0.3% | 582,387 | $1.4M |
| Royal Bank of Canada | 0.00% | Reduce -4.2% | 574,267 | $1.3M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -75.4% | 558,576 | $1.3M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +5.5% | 558,474 | $1.3M |
| Jane Street Group, LLC | 0.00% | Reduce -0.9% | 479,438 | $1.1M |
| 72 Investment Holdings, LLC | 1.63% | No change | 474,067 | $1.1M |
| Susquehanna International Group, LLP | 0.00% | Add +68.4% | 445,607 | $1.0M |
| XTX Topco Ltd | 0.05% | Add +319.6% | 441,541 | $1.0M |
| State Street Corp. | 0.00% | Add +7.8% | 386,263 | $900K |
| Green Alpha Advisors, LLC | 0.82% | Reduce -14.6% | 363,699 | $847K |
| Morgan Stanley | 0.00% | Add +8.1% | 358,219 | $835K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -63.5% | 349,083 | $813K |
| UBS Group AG | 0.00% | Add +28.2% | 319,292 | $744K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 130,000 | $716K |
| Point72 Asset Management | 0.00% | Reduce -0.4% | 288,547 | $672K |
| Citadel Advisors | 0.00% | Add +10.4% | 265,123 | $618K |
| Bruce & Co., Inc. | 0.18% | No change | 250,000 | $583K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -69.1% | 244,824 | $570K |
| Northern Trust Corp. | 0.00% | Reduce -3.3% | 205,072 | $478K |
| Milestone Asset Management, LLC | 0.08% | Reduce -57.0% | 175,967 | $410K |
| Bridgeway Capital Management, LLC | 0.01% | No change | 148,500 | $346K |
| Graham Capital Management, L.P. | 0.02% | New | 128,352 | $299K |
| Marshall Wace, LLP | 0.00% | New | 125,844 | $293K |
| Siren, L.L.C. | 0.01% | No change | 105,347 | $245K |
| Cubist Systematic Strategies, LLC | 0.00% | Reduce -69.9% | 92,762 | $216K |
| Catalyst Funds Management Pty Ltd | 0.03% | Add +128.2% | 88,300 | $206K |
| Ameriprise Financial Inc. | 0.00% | Reduce -72.4% | 85,354 | $199K |
| Nelson Capital Management, LLC | 0.02% | No change | 85,020 | $198K |
| American Century Companies Inc. | 0.00% | New | 81,802 | $191K |
| RBF Capital, LLC | 0.01% | No change | 80,000 | $186K |
| AQR Capital Management | 0.00% | Reduce -90.5% | 61,407 | $143K |
| Jefferies Financial Group Inc. | 0.00% | New | 47,200 | $110K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -21.7% | 46,933 | $109K |
| Qube Research & Technologies Ltd | 0.00% | New | 45,150 | $105K |
| &partners | 0.00% | Reduce -86.9% | 44,139 | $103K |
| Public Employees Retirement System of Ohio | 0.00% | Reduce -67.1% | 42,229 | $98K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +3.4% | 42,186 | $98K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -87.8% | 38,768 | $90K |
| Thrivent Financial for Lutherans | 0.00% | Reduce -87.0% | 35,562 | $83K |
| Prime Capital Investment Advisors, LLC | 0.00% | Reduce -8.7% | 34,674 | $81K |
| US Bancorp \de | 0.00% | Add +18624.0% | 34,265 | $80K |
| HSBC Holdings PLC | 0.00% | Reduce -69.9% | 34,460 | $78K |
| Thrive Wealth Management, LLC | 0.01% | No change | 32,000 | $75K |
| Susquehanna Portfolio Strategies, LLC | 0.00% | New | 29,883 | $70K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.01% | Reduce -50.2% | 29,658 | $69K |
| Credit Agricole S A | 0.00% | — | 29,000 | $68K |
| Wells Fargo & Company | 0.00% | Reduce -70.5% | 25,854 | $60K |
| Squarepoint Ops LLC | 0.00% | Reduce -18.9% | 24,110 | $56K |
| Barclays PLC | 0.00% | Add +0.4% | 21,772 | $51K |
| Simplex Trading, LLC | 0.00% | New | 21,123 | $49K |
| Next Capital Management LLC | 0.02% | No change | 20,000 | $47K |
| Liberty Wealth Management LLC | 0.01% | New | 19,500 | $45K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -74.0% | 19,219 | $45K |
| Creative Planning | 0.00% | Reduce -6.2% | 18,922 | $44K |
| HighTower Advisors, LLC | 0.00% | Reduce -1.2% | 16,934 | $39K |
| HBK Sorce Advisory LLC | 0.00% | No change | 12,344 | $35K |
| Cetera Investment Advisers | 0.00% | Add +17.6% | 14,883 | $35K |
| Bank of New York Mellon Corp | 0.00% | Add +0.3% | 14,051 | $33K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -40.1% | 13,523 | $32K |
| Pinnacle Wealth Management Advisory Group, LLC | 0.00% | No change | 12,903 | $30K |
| Pinnacle Associates Ltd. | 0.00% | No change | 12,903 | $30K |
| Capital Advisory Group Advisory Services, LLC | 0.01% | Add +7.1% | 12,314 | $29K |
| R Squared Ltd | 0.01% | New | 12,268 | $29K |
| Focus Partners Advisor Solutions, LLC | 0.00% | Reduce -21.4% | 12,251 | $29K |
| Invesco Ltd. | 0.00% | Reduce -50.7% | 12,207 | $28K |
| J.W. Cole Advisors, Inc. | 0.00% | Reduce -6.1% | 11,269 | $26K |
| NewEdge Advisors, LLC | 0.00% | No change | 10,400 | $24K |
| LPL Financial LLC | 0.00% | New | 10,296 | $24K |
| Modern Wealth Management, LLC | 0.00% | No change | 10,000 | $23K |
| Chevy Chase Trust Holdings, LLC | 0.00% | No change | 10,000 | $23K |
| FSA Wealth Management LLC | 0.01% | No change | 8,630 | $20K |
| Osaic Holdings, Inc. | 0.00% | Add +5.7% | 9,334 | $19K |
| Wealthspire Advisors, LLC | 0.00% | New | 7,500 | $17K |
| Group One Trading LLC | 0.00% | Reduce -76.5% | 6,084 | $14K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 4,428 | $10K |
| Atlantic Union Bankshares Corp | 0.00% | New | 3,200 | $7K |
| Federated Hermes, Inc. | 0.00% | Reduce -61.3% | 3,066 | $7K |
| Cwm, LLC | 0.00% | Reduce -92.8% | 2,435 | $6K |
| NFSG Corp | 0.00% | No change | 2,000 | $5K |
| BNP Paribas Financial Markets | 0.00% | Reduce -90.3% | 1,876 | $4K |
| Citigroup Inc. | 0.00% | Reduce -95.0% | 1,571 | $4K |
| Optiver Holding B.V. | 0.00% | No change | 1,104 | $3K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 1,026 | $2K |
| Harbour Investments, Inc. | 0.00% | No change | 1,000 | $2K |
"% of holder's portfolio" is CRBU's weight in each manager's 13F, not the share of Caribou Biosciences Inc. the manager owns.