Caribou BiosciencesCRBU
13F holders, Q4 2025 (December 31)124holders +7
18new positions
14sold out
6famous investors
$1.60avg. 13F price*
At the end of Q4 2025, 124 institutions reported holding Caribou Biosciences Inc. (CRBU) in their 13F filings, up 7 from Q3 2025. 18 opened new positions and 14 sold out. The largest holders were Pfizer Inc ($7.5M), Vanguard Group Inc. ($6.8M) and Kynam Capital Management, LP ($4.0M). 6 famous investors held it, including Lee Ainslie (0.0% of Maverick Capital's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Caribou Biosciences Inc.
- CUSIP
- 142038108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 18 | $1.8M |
| Exits | 14 | $3.6M |
All 13F filers, Q3 2025 → Q4 2025: 6,333,453 shares bought and 6,341,749 shares sold, net −8,296 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 124 holders
| Pfizer Inc | 3.15% | No change | 4,690,431 | $7.5M |
| Vanguard Group Inc. | 0.00% | Add +1.8% | 4,304,198 | $6.8M |
| Kynam Capital Management, LP | 0.26% | Reduce -18.4% | 2,503,302 | $4.0M |
| BlackRock, Inc. | 0.00% | Add +46.7% | 2,141,023 | $3.4M |
| Renaissance Technologies | 0.00% | Add +110.1% | 1,639,857 | $2.6M |
| Aberdeen Group plc | 0.00% | No change | 1,388,905 | $2.2M |
| Two Sigma Advisers, LP | 0.00% | Reduce -9.1% | 1,115,700 | $1.8M |
| Susquehanna International Group, LLP | 0.00% | Add +131.4% | 1,031,375 | $1.6M |
| Two Sigma Investments, LP | 0.00% | Add +30.2% | 1,020,079 | $1.6M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -16.9% | 1,006,010 | $1.6M |
| Bank of America Corp. | 0.00% | Reduce -7.6% | 993,186 | $1.6M |
| Geode Capital Management, LLC | 0.00% | Reduce -0.8% | 976,813 | $1.6M |
| PFM Health Sciences, LP | 0.16% | Reduce -29.5% | 957,787 | $1.5M |
| Marshall Wace, LLP | 0.00% | Add +600.2% | 881,105 | $1.4M |
| Jacobs Levy Equity Management, Inc. | 0.01% | Add +136.1% | 824,299 | $1.3M |
| Millennium Management | 0.00% | Reduce -76.2% | 767,002 | $1.2M |
| FMR LLC | 0.00% | Reduce -0.4% | 725,968 | $1.2M |
| Maverick Capital | 0.01% | No change | 652,542 | $1.0M |
| UBS Group AG | 0.00% | Add +99.7% | 637,745 | $1.0M |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -0.1% | 581,793 | $925K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -0.5% | 555,628 | $883K |
| Citadel Advisors | 0.00% | Add +94.4% | 515,429 | $820K |
| Goldman Sachs Group Inc. | 0.00% | Add +99.8% | 489,138 | $778K |
| 72 Investment Holdings, LLC | 1.49% | No change | 474,067 | $754K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 130,000 | $724K |
| State Street Corp. | 0.00% | Add +9.6% | 423,263 | $673K |
| XTX Topco Ltd | 0.02% | Reduce -6.4% | 413,380 | $657K |
| Point72 Asset Management | 0.00% | Add +40.0% | 403,938 | $642K |
| Green Alpha Advisors, LLC | 0.55% | Add +3.1% | 375,139 | $596K |
| Gsa Capital Partners LLP | 0.05% | New | 371,372 | $590K |
| Morgan Stanley | 0.00% | Reduce -16.7% | 298,456 | $475K |
| Jane Street Group, LLC | 0.00% | Reduce -38.3% | 295,685 | $470K |
| Bruce & Co., Inc. | 0.12% | No change | 250,000 | $398K |
| Milestone Asset Management, LLC | 0.07% | Add +31.7% | 231,799 | $369K |
| Northern Trust Corp. | 0.00% | Add +6.2% | 217,735 | $346K |
| Qube Research & Technologies Ltd | 0.00% | Add +353.3% | 204,652 | $325K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 178,100 | $283K |
| Quadrature Capital Ltd | 0.00% | New | 159,317 | $253K |
| Bridgeway Capital Management, LLC | 0.00% | No change | 148,500 | $236K |
| Wells Fargo & Company | 0.00% | Add +449.0% | 141,943 | $226K |
| Nano Cap New Millennium Growth Fund L P | 0.15% | — | 112,500 | $179K |
| American Century Companies Inc. | 0.00% | Add +37.5% | 112,453 | $179K |
| Graham Capital Management, L.P. | 0.01% | Reduce -16.4% | 107,253 | $171K |
| Siren, L.L.C. | 0.01% | No change | 105,347 | $168K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | New | 85,246 | $136K |
| Ameriprise Financial Inc. | 0.00% | Reduce -0.3% | 85,104 | $135K |
| Keystone Financial Group | 0.01% | New | 80,475 | $128K |
| ExodusPoint Capital Management, LP | 0.00% | New | 77,704 | $124K |
| Citigroup Inc. | 0.00% | Add +4646.7% | 74,571 | $119K |
| Acadian Asset Management LLC | 0.00% | New | 59,722 | $94K |
| Nelson Capital Management, LLC | 0.01% | Reduce -31.0% | 58,685 | $93K |
| Squarepoint Ops LLC | 0.00% | Add +132.0% | 55,938 | $89K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -2.2% | 45,908 | $73K |
| Jefferies Financial Group Inc. | 0.00% | Reduce -5.0% | 44,840 | $71K |
| Lighthouse Investment Partners, LLC | 0.00% | New | 44,160 | $70K |
| Public Employees Retirement System of Ohio | 0.00% | No change | 42,229 | $67K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -0.2% | 42,113 | $67K |
| RBF Capital, LLC | 0.00% | Reduce -50.0% | 40,000 | $64K |
| Man Group plc | 0.00% | New | 36,712 | $58K |
| &partners | 0.00% | Reduce -19.6% | 35,505 | $56K |
| Invesco Ltd. | 0.00% | Add +187.2% | 35,063 | $56K |
| HSBC Holdings PLC | 0.00% | No change | 34,460 | $55K |
| US Bancorp \de | 0.00% | No change | 34,265 | $54K |
| Prime Capital Investment Advisors, LLC | 0.00% | Reduce -2.1% | 33,934 | $54K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -16.7% | 32,307 | $51K |
| Thrive Wealth Management, LLC | 0.01% | No change | 32,000 | $51K |
| Credit Agricole S A | 0.00% | No change | 29,000 | $46K |
| AQR Capital Management | 0.00% | Reduce -58.4% | 25,561 | $41K |
| Russell Investments Group, Ltd. | 0.00% | Add +80.0% | 24,347 | $39K |
| Barclays PLC | 0.00% | Reduce -0.4% | 21,688 | $34K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +5.9% | 20,351 | $32K |
| Next Capital Management LLC | 0.01% | No change | 20,000 | $32K |
| Liberty Wealth Management LLC | 0.00% | No change | 19,500 | $31K |
| Creative Planning | 0.00% | Reduce -2.2% | 18,500 | $29K |
| HighTower Advisors, LLC | 0.00% | No change | 16,934 | $27K |
| Cetera Investment Advisers | 0.00% | Add +6.0% | 15,781 | $25K |
| Bronte Capital Management Pty Ltd. | 0.00% | New | 15,627 | $25K |
| LPL Financial LLC | 0.00% | Add +50.8% | 15,524 | $25K |
| China Universal Asset Management Co., Ltd. | 0.00% | New | 15,231 | $24K |
| Royal Bank of Canada | 0.00% | Reduce -97.4% | 14,874 | $24K |
| Modern Wealth Management, LLC | 0.00% | Add +50.0% | 15,000 | $24K |
| Bank of New York Mellon Corp | 0.00% | Reduce -7.8% | 12,956 | $21K |
| Pinnacle Wealth Management Advisory Group, LLC | 0.00% | No change | 12,903 | $21K |
| Pinnacle Associates Ltd. | 0.00% | No change | 12,903 | $21K |
| Capital Advisory Group Advisory Services, LLC | 0.01% | No change | 12,314 | $20K |
| Focus Partners Advisor Solutions, LLC | 0.00% | Reduce -0.3% | 12,216 | $19K |
| HBK Sorce Advisory LLC | 0.00% | No change | 12,344 | $19K |
| J.W. Cole Advisors, Inc. | 0.00% | No change | 11,269 | $18K |
| Osaic Holdings, Inc. | 0.00% | Add +14.6% | 10,693 | $17K |
| NewEdge Advisors, LLC | 0.00% | No change | 10,400 | $17K |
| Chevy Chase Trust Holdings, LLC | 0.00% | No change | 10,000 | $16K |
| Allworth Financial LP | 0.00% | New | 9,430 | $15K |
| Canada Pension Plan Investment Board | 0.00% | New | 7,400 | $12K |
| JPMorgan Chase & Co. | 0.00% | New | 6,601 | $10K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | New | 4,542 | $7K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -0.1% | 4,422 | $7K |
| Larson Financial Group LLC | 0.00% | New | 4,066 | $6K |
| Atlantic Union Bankshares Corp | 0.00% | No change | 3,200 | $5K |
| Hilton Head Capital Partners, LLC | 0.00% | — | 3,000 | $5K |
| Federated Hermes, Inc. | 0.00% | Reduce -11.2% | 2,722 | $4K |
"% of holder's portfolio" is CRBU's weight in each manager's 13F, not the share of Caribou Biosciences Inc. the manager owns.