Definium TherapeuticsDFTX
13F holders, Q2 2026 (June 30)361holders +115
143new positions
29sold out
8famous investors
$46.60avg. 13F price*
At the end of Q2 2026, 361 institutions reported holding Definium Therapeutics Inc. (DFTX) in their 13F filings, up 115 from Q1 2026. 143 opened new positions and 29 sold out. The largest holders were BlackRock, Inc. ($528.4M), Avoro Capital Advisors LLC ($338.2M) and Driehaus Capital Management LLC ($322.0M). 8 famous investors held it, including Stanley Druckenmiller (0.4% of Duquesne Family Office's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Ron Baron (0.0% of Baron Capital (BAMCO)'s portfolio).
- Company
- Definium Therapeutics Inc.
- CUSIP
- 24477V105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 143 | $825.0M |
| Exits | 29 | $60.2M |
All 13F filers, Q1 2026 → Q2 2026: 44,138,634 shares bought and 9,515,008 shares sold, net +34,623,626 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 361 holders
| BlackRock, Inc. | 0.01% | Add +32.5% | 11,232,834 | $528.4M |
| Avoro Capital Advisors LLC | 3.04% | Add +43.8% | 7,188,888 | $338.2M |
| Driehaus Capital Management LLC | 1.87% | Add +15.8% | 6,845,276 | $322.0M |
| Jupiter Topco LLC | 0.11% | — | 5,615,645 | $264.0M |
| Capital World Investors | 0.03% | New | 5,367,723 | $252.5M |
| FMR LLC | 0.01% | Add +162.7% | 4,752,921 | $223.6M |
| T. Rowe Price Associates Inc. | 0.02% | Add +6545.7% | 4,652,032 | $218.8M |
| Geode Capital Management, LLC | 0.01% | Add +46.1% | 3,644,813 | $171.5M |
| State Street Corp. | 0.00% | Add +24.0% | 3,065,390 | $144.2M |
| Capital International Investors | 0.03% | New | 2,963,410 | $139.4M |
| Octagon Capital Advisors LP | 12.74% | Add +20.9% | 2,950,000 | $138.8M |
| Wellington Management Group LLP | 0.02% | Add +126.1% | 2,949,734 | $138.8M |
| Deep Track Capital, LP | 1.91% | Reduce -8.3% | 2,750,000 | $129.4M |
| Commodore Capital LP | 5.60% | No change | 2,000,000 | $94.1M |
| Goldman Sachs Group Inc. | 0.01% | Add +7.5% | 1,800,852 | $84.7M |
| Citadel Advisors | 0.05% | Add +26.6% | 1,688,587 | $79.4M |
| Vanguard Portfolio Management LLC | 0.00% | Add +88.9% | 1,648,426 | $77.5M |
| Ra Capital Management, L.P. | 0.61% | New | 1,500,000 | $70.6M |
| Vanguard Capital Management LLC | 0.00% | Add +35.5% | 1,486,454 | $69.9M |
| Siren, L.L.C. | 1.36% | Add +54.4% | 1,419,493 | $66.8M |
| Marshall Wace, LLP | 0.05% | Add +8.2% | 1,298,946 | $61.1M |
| Northern Trust Corp. | 0.01% | Add +46.3% | 1,169,238 | $55.0M |
| Ameriprise Financial Inc. | 0.01% | Add +18.8% | 1,148,363 | $54.0M |
| Nuveen, LLC | 0.01% | Add +58.3% | 1,105,314 | $52.0M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +34.0% | 1,083,576 | $51.0M |
| Woodline Partners LP | 0.15% | Add +33.3% | 1,003,641 | $47.2M |
| Adage Capital Partners Gp, L.L.C. | 0.07% | Reduce -13.0% | 1,000,000 | $47.0M |
| Boxer Capital Management, LLC | 3.54% | Add +66.8% | 998,500 | $47.0M |
| Two Sigma Investments, LP | 0.03% | Reduce -23.3% | 921,818 | $43.4M |
| Balyasny Asset Management L.P. | 0.08% | Reduce -29.6% | 897,658 | $42.2M |
| Vanguard Fiduciary Trust Co. | 0.01% | Add +43.7% | 827,693 | $38.9M |
| Holocene Advisors, LP | 0.09% | Reduce -27.1% | 796,574 | $37.5M |
| AWM Investment Company, Inc. | 3.20% | Reduce -27.1% | 784,800 | $36.9M |
| Bank of New York Mellon Corp | 0.01% | Add +3.2% | 777,271 | $36.6M |
| Polar Capital Holdings Plc | 0.10% | New | 777,253 | $36.6M |
| Alliancebernstein L.P. | 0.01% | Add +1866.4% | 1,803,287 | $34.1M |
| Eventide Asset Management, LLC | 0.45% | Add +3.5% | 710,000 | $33.4M |
| Neuberger Berman Group LLC | 0.02% | Add +415.5% | 687,539 | $32.3M |
| Qube Research & Technologies Ltd | 0.04% | Add +60.3% | 682,901 | $32.1M |
| Candriam S.C.A. | 0.13% | Reduce -52.5% | 614,425 | $28.9M |
| ArrowMark Colorado Holdings LLC | 1.11% | Reduce -64.6% | 564,069 | $26.5M |
| Catalio Capital Management, LP | 4.97% | Reduce -45.8% | 562,672 | $26.5M |
| Blackstone Inc. | 0.09% | Add +10.4% | 561,612 | $26.4M |
| Integral Health Asset Management, LLC | 1.06% | Add +37.5% | 550,000 | $25.9M |
| Baron Capital (BAMCO) | 0.04% | New | 520,108 | $24.5M |
| UBS Group AG | 0.00% | Add +1.1% | 499,467 | $23.5M |
| Franklin Resources Inc. | 0.01% | New | 486,219 | $22.9M |
| Point72 Asset Management | 0.04% | Add +175.8% | 483,980 | $22.8M |
| Ensign Peak Advisors, Inc | 0.04% | Reduce -14.8% | 466,106 | $21.9M |
| Morgan Stanley | 0.00% | Add +3.7% | 454,912 | $21.4M |
| Great Point Partners LLC | 4.71% | New | 425,000 | $20.0M |
| Silverarc Capital Management, LLC | 2.09% | New | 400,000 | $18.8M |
| Cormorant Asset Management, LP | 0.96% | New | 400,000 | $18.8M |
| RTW Investments, LP | 0.16% | Add +33.3% | 400,000 | $18.8M |
| Assetmark, Inc. | 0.03% | New | 396,542 | $18.7M |
| Orbimed Advisors LLC | 0.33% | Reduce -54.5% | 365,400 | $17.2M |
| Duquesne Family Office | 0.39% | New | 356,600 | $16.8M |
| D. E. Shaw & Co. | 0.01% | Add +16.1% | 315,410 | $14.8M |
| Tetragon Partners GP Ltd | 2.20% | Add +43.5% | 286,990 | $13.5M |
| Millennium Management | 0.01% | Reduce -68.6% | 266,076 | $12.5M |
| JPMorgan Chase & Co. | 0.00% | Add +0.5% | 265,955 | $12.4M |
| Sofinnova Investments, Inc. | 0.64% | Reduce -25.6% | 255,903 | $12.0M |
| PFM Health Sciences, LP | 1.02% | Add +21.3% | 249,020 | $11.7M |
| HighVista Strategies LLC | 2.60% | Add +30.7% | 242,884 | $11.4M |
| Trexquant Investment LP | 0.07% | New | 233,199 | $11.0M |
| Seven Grand Managers, LLC | 0.43% | No change | 225,000 | $10.6M |
| Swiss National Bank | 0.01% | Add +39.6% | 221,200 | $10.4M |
| Eversept Partners, LP | 0.56% | Add +35.1% | 217,185 | $10.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +8651.9% | 211,183 | $9.9M |
| TD Asset Management Inc | 0.01% | New | 209,460 | $9.9M |
| Royce & Associates LP | 0.08% | Reduce -10.9% | 208,551 | $9.8M |
| SEB Asset Management AB | 0.04% | New | 208,254 | $9.8M |
| Superstring Capital Management LP | 5.59% | Reduce -46.4% | 188,282 | $8.9M |
| Emerald Advisers, LLC | 0.20% | New | 178,751 | $8.4M |
| Aberdeen Group plc | 0.01% | New | 175,000 | $8.2M |
| Bank of America Corp. | 0.00% | Add +3.9% | 164,575 | $7.7M |
| Tri Locum Partners LP | 0.94% | Reduce -55.9% | 162,996 | $7.7M |
| Rhumbline Advisers | 0.01% | Add +31.8% | 158,096 | $7.4M |
| Brevan Howard Capital Management LP | 0.11% | Reduce -25.9% | 156,812 | $7.4M |
| Russell Investments Group, Ltd. | 0.01% | Add +28.5% | 153,477 | $7.2M |
| LMR Partners LLP | 0.06% | New | 150,200 | $7.1M |
| Seven Fleet Capital Management LP | 1.15% | Add +48.8% | 148,647 | $7.0M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +454.3% | 146,368 | $6.9M |
| Rock Springs Capital Management LP | 0.33% | New | 143,187 | $6.7M |
| Deutsche Bank AG | 0.00% | Reduce -65.3% | 142,947 | $6.7M |
| SummitTX Capital, L.P. | 0.18% | New | 142,489 | $6.7M |
| Stempoint Capital LP | 1.12% | Reduce -57.9% | 137,124 | $6.5M |
| AQR Capital Management | 0.00% | Add +135.0% | 134,152 | $6.3M |
| California State Teachers Retirement System | 0.01% | New | 128,346 | $6.0M |
| BIT Capital GmbH | 0.21% | Reduce -53.8% | 128,131 | $6.0M |
| Fred Alger Management, LLC | 0.02% | Add +35.9% | 125,256 | $5.9M |
| Wells Fargo & Company | 0.00% | Add +205.3% | 122,033 | $5.7M |
| Atika Capital Management LLC | 0.57% | New | 122,000 | $5.7M |
| AdvisorShares Investments LLC | 0.69% | Add +33.0% | 121,381 | $5.7M |
| Emerald Mutual Fund Advisers Trust | 0.20% | New | 121,249 | $5.7M |
| Informed Momentum Co LLC | 0.51% | New | 120,928 | $5.7M |
| Schonfeld Strategic Advisors LLC | 0.03% | Add +1048.8% | 119,610 | $5.6M |
| HSBC Holdings PLC | 0.00% | New | 117,482 | $5.5M |
| Alps Advisors Inc. | 0.02% | New | 110,388 | $5.2M |
| Data Collective IV GP, LLC | 6.01% | No change | 100,350 | $4.7M |
"% of holder's portfolio" is DFTX's weight in each manager's 13F, not the share of Definium Therapeutics Inc. the manager owns.