Definium TherapeuticsDFTX
13F holders, Q1 2026 (March 31)246holders +238
62new positions
1sold out
5famous investors
$18.89avg. 13F price*
At the end of Q1 2026, 246 institutions reported holding Definium Therapeutics Inc. (DFTX) in their 13F filings, up 238 from Q4 2025. 62 opened new positions and 1 sold out. The largest holders were BlackRock, Inc. ($160.3M), Driehaus Capital Management LLC ($111.7M) and Avoro Capital Advisors LLC ($94.5M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Definium Therapeutics Inc.
- CUSIP
- 24477V105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 62 | $155.2M |
| Exits | 1 | $411K |
All 13F filers, Q4 2025 → Q1 2026: 19,658,272 shares bought and 8,325,956 shares sold, net +11,332,316 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 246 holders
| BlackRock, Inc. | 0.00% | Add +2.5% | 8,480,230 | $160.3M |
| Driehaus Capital Management LLC | 0.82% | Reduce -9.6% | 5,911,889 | $111.7M |
| Avoro Capital Advisors LLC | 0.93% | No change | 5,000,000 | $94.5M |
| Janus Henderson Group PLC | 0.03% | Add +47.5% | 3,556,041 | $67.2M |
| Deep Track Capital, LP | 1.17% | Add +78.9% | 3,000,000 | $56.7M |
| Geode Capital Management, LLC | 0.00% | Add +7.0% | 2,495,399 | $47.2M |
| State Street Corp. | 0.00% | Add +4.4% | 2,471,873 | $46.7M |
| Octagon Capital Advisors LP | 5.10% | Add +9.4% | 2,440,000 | $46.1M |
| Commodore Capital LP | 2.19% | No change | 2,000,000 | $37.8M |
| FMR LLC | 0.00% | Add +1016.7% | 1,809,610 | $34.2M |
| Trails Edge Capital Partners, LP | 7.73% | Reduce -32.3% | 1,738,110 | $32.9M |
| Goldman Sachs Group Inc. | 0.00% | Add +81.1% | 1,675,411 | $31.7M |
| ArrowMark Colorado Holdings LLC | 0.80% | New | 1,594,717 | $30.1M |
| Citadel Advisors | 0.02% | Add +535.1% | 1,333,442 | $25.2M |
| Wellington Management Group LLP | 0.00% | Add +6.9% | 1,304,749 | $24.7M |
| Candriam S.C.A. | 0.13% | Add +33.2% | 1,293,629 | $24.4M |
| Balyasny Asset Management L.P. | 0.05% | Reduce -2.6% | 1,274,221 | $24.1M |
| Two Sigma Investments, LP | 0.02% | Add +182.6% | 1,201,610 | $22.7M |
| Marshall Wace, LLP | 0.02% | Reduce -59.6% | 1,200,825 | $22.7M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | No change | 1,150,000 | $21.7M |
| Vanguard Capital Management LLC | 0.00% | — | 1,096,978 | $20.7M |
| Holocene Advisors, LP | 0.05% | New | 1,091,967 | $20.6M |
| AWM Investment Company, Inc. | 2.25% | Reduce -22.6% | 1,076,893 | $20.4M |
| Catalio Capital Management, LP | 4.10% | New | 1,037,984 | $19.6M |
| Ameriprise Financial Inc. | 0.00% | Add +91.7% | 966,608 | $18.3M |
| Siren, L.L.C. | 0.48% | Add +14.9% | 919,493 | $17.4M |
| Vanguard Portfolio Management LLC | 0.00% | — | 872,665 | $16.5M |
| Millennium Management | 0.01% | Reduce -38.8% | 846,896 | $16.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.2% | 808,715 | $15.3M |
| Orbimed Advisors LLC | 0.34% | Reduce -34.5% | 804,000 | $15.2M |
| Northern Trust Corp. | 0.00% | Add +8.8% | 798,987 | $15.1M |
| Bank of New York Mellon Corp | 0.00% | Add +152.1% | 752,922 | $14.2M |
| Woodline Partners LP | 0.05% | Add +400.0% | 752,792 | $14.2M |
| Nuveen, LLC | 0.00% | Add +152.5% | 698,130 | $13.2M |
| Eventide Asset Management, LLC | 0.21% | New | 686,162 | $13.0M |
| Boxer Capital Management, LLC | 1.49% | No change | 598,500 | $11.3M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 575,937 | $10.9M |
| Ensign Peak Advisors, Inc | 0.02% | Add +108.7% | 546,783 | $10.3M |
| Blackstone Inc. | 0.04% | Reduce -75.3% | 508,668 | $9.6M |
| UBS Group AG | 0.00% | Reduce -27.8% | 493,977 | $9.3M |
| Morgan Stanley | 0.00% | Add +19.6% | 438,573 | $8.3M |
| Qube Research & Technologies Ltd | 0.01% | New | 426,055 | $8.1M |
| Deutsche Bank AG | 0.00% | Add +3.4% | 411,834 | $7.8M |
| Integral Health Asset Management, LLC | 0.40% | Add +14.3% | 400,000 | $7.6M |
| Tri Locum Partners LP | 0.98% | New | 369,588 | $7.0M |
| Superstring Capital Management LP | 4.75% | Reduce -17.3% | 351,461 | $6.6M |
| Sofinnova Investments, Inc. | 0.33% | New | 344,166 | $6.5M |
| Patient Square Capital LP | 1.11% | New | 331,000 | $6.3M |
| Stempoint Capital LP | 1.18% | New | 325,483 | $6.2M |
| RTW Investments, LP | 0.06% | No change | 300,000 | $5.7M |
| BIT Capital GmbH | 0.29% | New | 277,511 | $5.2M |
| D. E. Shaw & Co. | 0.00% | Reduce -7.5% | 271,717 | $5.1M |
| Jane Street Group, LLC | 0.01% | Reduce -51.5% | 260,241 | $4.9M |
| JPMorgan Chase & Co. | 0.00% | Add +72.1% | 264,545 | $4.6M |
| Royce & Associates LP | 0.04% | Add +42.7% | 234,051 | $4.4M |
| Seven Grand Managers, LLC | 0.28% | No change | 225,000 | $4.3M |
| Brevan Howard Capital Management LP | 0.04% | Add +1802.9% | 211,488 | $4.0M |
| PFM Health Sciences, LP | 0.42% | New | 205,317 | $3.9M |
| Tetragon Partners GP Ltd | 0.74% | New | 199,994 | $3.8M |
| HighVista Strategies LLC | 0.97% | New | 185,856 | $3.5M |
| Point72 Asset Management | 0.01% | Reduce -2.7% | 175,490 | $3.3M |
| Eversept Partners, LP | 0.20% | New | 160,723 | $3.0M |
| Swiss National Bank | 0.00% | No change | 158,400 | $3.0M |
| Bank of America Corp. | 0.00% | Add +43.3% | 158,345 | $3.0M |
| Soviero Asset Management, LP | 1.49% | Reduce -6.7% | 140,000 | $2.6M |
| Neuberger Berman Group LLC | 0.00% | New | 133,369 | $2.5M |
| Squarepoint Ops LLC | 0.01% | Add +176.5% | 125,522 | $2.4M |
| Rosalind Advisors, Inc. | 0.97% | Reduce -83.3% | 125,000 | $2.4M |
| Rhumbline Advisers | 0.00% | Add +8.3% | 119,972 | $2.3M |
| Russell Investments Group, Ltd. | 0.00% | Add +1247.6% | 119,464 | $2.3M |
| ExodusPoint Capital Management, LP | 0.02% | Add +453.7% | 104,915 | $2.0M |
| Data Collective IV GP, LLC | 3.39% | No change | 100,350 | $1.9M |
| Burkehill Global Management, LP | 0.10% | No change | 100,000 | $1.9M |
| Seven Fleet Capital Management LP | 0.59% | New | 99,887 | $1.9M |
| Royal Bank of Canada | 0.00% | Add +3.8% | 97,192 | $1.8M |
| Fred Alger Management, LLC | 0.01% | New | 92,165 | $1.7M |
| Alliancebernstein L.P. | 0.00% | Add +22.5% | 91,703 | $1.7M |
| AdvisorShares Investments LLC | 0.31% | Reduce -11.2% | 91,301 | $1.7M |
| HRT Financial LP | 0.00% | Add +239.2% | 89,141 | $1.7M |
| Invesco Ltd. | 0.00% | Add +65.1% | 88,121 | $1.7M |
| Group One Trading LLC | 0.05% | New | 87,832 | $1.7M |
| Susquehanna International Group, LLP | 0.00% | Reduce -82.9% | 81,456 | $1.5M |
| LPL Financial LLC | 0.00% | Add +1.3% | 78,271 | $1.5M |
| T. Rowe Price Associates Inc. | 0.00% | Add +34.0% | 70,001 | $1.3M |
| Platinum Investment Management Ltd. | 0.33% | No change | 70,000 | $1.3M |
| Legal & General Group Plc | 0.00% | Reduce -10.7% | 59,799 | $1.1M |
| Ikarian Capital, LLC | 0.16% | No change | 58,803 | $1.1M |
| AQR Capital Management | 0.00% | Reduce -2.1% | 57,094 | $1.1M |
| Rockefeller Capital Management L.P. | 0.00% | Add +15628.2% | 55,206 | $1.0M |
| MetLife Investment Management, LLC | 0.01% | Add +3.2% | 54,261 | $1.0M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 54,018 | $1.0M |
| Blair William & Co. | 0.00% | New | 53,695 | $1.0M |
| Kestra Private Wealth Services, LLC | 0.01% | Add +0.9% | 50,588 | $956K |
| State of Wisconsin Investment Board | 0.00% | Reduce -14.0% | 50,420 | $953K |
| Nisa Investment Advisors, LLC | 0.00% | Add +1.1% | 48,903 | $924K |
| Vanguard Global Advisers, LLC | 0.00% | — | 48,044 | $908K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +5.6% | 46,193 | $873K |
| Allstate Corp. | 0.01% | New | 45,366 | $857K |
| CenterBook Partners LP | 0.04% | Reduce -69.2% | 42,829 | $809K |
| Twinbeech Capital LP | 0.08% | New | 42,100 | $796K |
"% of holder's portfolio" is DFTX's weight in each manager's 13F, not the share of Definium Therapeutics Inc. the manager owns.