Design TherapeuticsDSGN
13F holders, Q1 2025 (March 31)98holders +3
13new positions
10sold out
6famous investors
$3.86avg. 13F price*
At the end of Q1 2025, 98 institutions reported holding Design Therapeutics Inc. (DSGN) in their 13F filings, up 3 from Q4 2024. 13 opened new positions and 10 sold out. The largest holders were SR One Capital Management, LP ($25.2M), Logos Global Management LP ($16.3M) and BlackRock, Inc. ($9.6M). 6 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Design Therapeutics Inc.
- CUSIP
- 25056L103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 13 | $7.3M |
| Exits | 10 | $4.6M |
All 13F filers, Q4 2024 → Q1 2025: 2,582,765 shares bought and 1,573,274 shares sold, net +1,009,491 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 98 holders
| SR One Capital Management, LP | 6.47% | No change | 6,526,476 | $25.2M |
| Logos Global Management LP | 2.89% | No change | 4,217,627 | $16.3M |
| BlackRock, Inc. | 0.00% | Reduce -3.9% | 2,479,963 | $9.6M |
| Frazier Life Sciences Management, L.P. | 0.35% | No change | 1,953,547 | $7.5M |
| Point72 Asset Management | 0.02% | Reduce -2.1% | 1,817,858 | $7.0M |
| Baker Bros. Advisors LP | 0.08% | No change | 1,743,725 | $6.7M |
| Tang Capital Management LLC | 0.36% | Add +13.5% | 1,680,975 | $6.5M |
| Almitas Capital LLC | 1.87% | Add +9.8% | 1,452,896 | $5.6M |
| Vanguard Group Inc. | 0.00% | Reduce -0.2% | 1,427,467 | $5.5M |
| Citadel Advisors | 0.00% | Add +0.5% | 963,460 | $3.7M |
| FMR LLC | 0.00% | Reduce -0.4% | 948,050 | $3.7M |
| Driehaus Capital Management LLC | 0.03% | Add +17.7% | 913,399 | $3.5M |
| Kynam Capital Management, LP | 0.30% | New | 904,017 | $3.5M |
| Geode Capital Management, LLC | 0.00% | Add +1.8% | 775,497 | $3.0M |
| State Street Corp. | 0.00% | Reduce -1.3% | 714,074 | $2.8M |
| Woodline Partners LP | 0.02% | New | 645,694 | $2.5M |
| Acadian Asset Management LLC | 0.01% | Add +11.2% | 630,953 | $2.4M |
| MPM Bioimpact LLC | 0.37% | Add +0.6% | 562,943 | $2.2M |
| D. E. Shaw & Co. | 0.00% | Reduce -22.9% | 395,251 | $1.5M |
| Northern Trust Corp. | 0.00% | Reduce -3.7% | 373,653 | $1.4M |
| Dimensional Fund Advisors LP | 0.00% | Add +34.1% | 288,602 | $1.1M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -10.5% | 266,016 | $1.0M |
| Renaissance Technologies | 0.00% | Add +4.5% | 265,000 | $1.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -2.4% | 258,375 | $997K |
| Morgan Stanley | 0.00% | Reduce -28.4% | 247,878 | $957K |
| Nuveen, LLC | 0.00% | — | 147,228 | $568K |
| Two Sigma Advisers, LP | 0.00% | Reduce -37.3% | 146,700 | $566K |
| Wellington Management Group LLP | 0.00% | New | 141,519 | $546K |
| Two Sigma Investments, LP | 0.00% | Reduce -36.9% | 128,747 | $497K |
| Bridgeway Capital Management, LLC | 0.01% | Reduce -11.4% | 113,800 | $439K |
| Bank of New York Mellon Corp | 0.00% | No change | 95,348 | $368K |
| Millennium Management | 0.00% | New | 87,988 | $340K |
| Barclays PLC | 0.00% | Reduce -18.9% | 84,006 | $324K |
| Gsa Capital Partners LLP | 0.03% | Reduce -39.0% | 72,149 | $278K |
| Lynx1 Capital Management LP | 0.09% | New | 65,954 | $255K |
| Palumbo Wealth Management LLC | 0.08% | Add +6.5% | 58,278 | $225K |
| Prudential Financial Inc. | 0.00% | Add +0.2% | 56,405 | $218K |
| BNP Paribas Financial Markets | 0.00% | Add +31.2% | 52,872 | $204K |
| Rhumbline Advisers | 0.00% | Reduce -12.4% | 46,369 | $179K |
| American Century Companies Inc. | 0.00% | Add +13.6% | 44,415 | $171K |
| Susquehanna International Group, LLP | 0.00% | Add +15.8% | 43,223 | $167K |
| Alliancebernstein L.P. | 0.00% | No change | 42,090 | $162K |
| Assenagon Asset Management S.A. | 0.00% | Reduce -34.8% | 36,917 | $143K |
| UBS Group AG | 0.00% | Reduce -50.7% | 32,819 | $127K |
| AQR Capital Management | 0.00% | Add +6.3% | 31,740 | $123K |
| Deutsche Bank AG | 0.00% | Add +0.1% | 28,129 | $109K |
| Corient Private Wealth LP | 0.00% | No change | 26,965 | $104K |
| Citigroup Inc. | 0.00% | Reduce -6.5% | 22,879 | $88K |
| STRS Ohio | 0.00% | Reduce -30.7% | 22,600 | $87K |
| Bank of America Corp. | 0.00% | Reduce -37.0% | 22,166 | $86K |
| State of Wisconsin Investment Board | 0.00% | New | 21,962 | $85K |
| Intech Investment Management LLC | 0.00% | Add +16.3% | 20,550 | $79K |
| JPMorgan Chase & Co. | 0.00% | Reduce -78.4% | 19,277 | $74K |
| MetLife Investment Management, LLC | 0.00% | Reduce -1.9% | 18,962 | $73K |
| Wells Fargo & Company | 0.00% | Add +2.3% | 18,846 | $73K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.3% | 18,737 | $72K |
| Jane Street Group, LLC | 0.00% | New | 18,125 | $70K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -4.3% | 17,482 | $67K |
| Mariner, LLC | 0.00% | Reduce -4.8% | 15,471 | $60K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.4% | 15,383 | $59K |
| Caz Investments LP | 0.42% | No change | 15,000 | $58K |
| Kennedy Capital Management LLC | 0.00% | Add +0.8% | 14,383 | $56K |
| Velan Capital Investment Management LP | 0.06% | New | 14,000 | $54K |
| T. Rowe Price Associates Inc. | 0.00% | Add +5.0% | 13,069 | $51K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -0.9% | 12,957 | $50K |
| SG Americas Securities, LLC | 0.00% | Reduce -5.0% | 12,980 | $50K |
| Nisa Investment Advisors, LLC | 0.00% | Add +0.5% | 11,916 | $46K |
| China Universal Asset Management Co., Ltd. | 0.00% | Reduce -5.4% | 11,357 | $44K |
| Invesco Ltd. | 0.00% | Reduce -2.2% | 11,331 | $44K |
| PNC Financial Services Group, Inc. | 0.00% | Add +0.3% | 9,251 | $36K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +348.7% | 7,902 | $31K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 6,598 | $25K |
| Russell Investments Group, Ltd. | 0.00% | Add +28.8% | 3,940 | $15K |
| CoreCap Advisors, LLC | 0.00% | Add +304.4% | 2,879 | $11K |
| Royal Bank of Canada | 0.00% | Reduce -31.0% | 2,806 | $11K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 2,570 | $10K |
| Legal & General Group Plc | 0.00% | No change | 2,565 | $10K |
| California State Teachers Retirement System | 0.00% | No change | 2,275 | $9K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | New | 2,165 | $8K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.4% | 1,895 | $8K |
| New York State Common Retirement Fund | 0.00% | No change | 2,026 | $8K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 1,449 | $6K |
| Amalgamated Bank | 0.00% | No change | 1,176 | $5K |
| Clearstead Advisors, LLC | 0.00% | No change | 610 | $2K |
| Private Wealth Management Group, LLC | 0.00% | No change | 558 | $2K |
| Sterling Capital Management LLC | 0.00% | Reduce -46.1% | 542 | $2K |
| Coldstream Capital Management Inc. | 0.00% | New | 535 | $2K |
| Daiwa Securities Group Inc. | 0.00% | New | 350 | $1K |
| Simplex Trading, LLC | 0.00% | Reduce -94.9% | 263 | $1K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 239 | $923 |
| GAMMA Investing LLC | 0.00% | Reduce -78.7% | 228 | $880 |
| Principal Securities, Inc. | 0.00% | No change | 74 | $457 |
| Osaic Holdings, Inc. | 0.00% | Reduce -32.9% | 49 | $189 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 31 | $120 |
| Brooklyn Investment Group | 0.00% | New | 19 | $74 |
| Farther Finance Advisors, LLC | 0.00% | No change | 19 | $68 |
| Cwm, LLC | 0.00% | Reduce -21.3% | 111 | $0 |
| Capital Advisors, Ltd. LLC | 0.00% | No change | 12 | $0 |
"% of holder's portfolio" is DSGN's weight in each manager's 13F, not the share of Design Therapeutics Inc. the manager owns.