Dyne TherapeuticsDYN
13F holders, Q4 2025 (December 31)233holders +26
51new positions
28sold out
7famous investors
$19.56avg. 13F price*
At the end of Q4 2025, 233 institutions reported holding Dyne Therapeutics Inc. (DYN) in their 13F filings, up 26 from Q3 2025. 51 opened new positions and 28 sold out. The largest holders were T. Rowe Price Investment Management, Inc. ($343.1M), Janus Henderson Group PLC ($271.6M) and Vanguard Group Inc. ($219.4M). 7 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Dyne Therapeutics Inc.
- CUSIP
- 26818M108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 51 | $254.6M |
| Exits | 28 | $113.0M |
All 13F filers, Q3 2025 → Q4 2025: 49,587,220 shares bought and 26,759,094 shares sold, net +22,828,126 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 233 holders
| T. Rowe Price Investment Management, Inc. | 0.22% | Add +523.7% | 17,540,089 | $343.1M |
| Janus Henderson Group PLC | 0.12% | Reduce -5.8% | 13,887,722 | $271.6M |
| Vanguard Group Inc. | 0.00% | Add +14.9% | 11,215,565 | $219.4M |
| BlackRock, Inc. | 0.00% | Add +16.1% | 11,190,838 | $218.9M |
| Atlas Venture Life Science Advisors, LLC | 20.64% | No change | 9,130,465 | $178.6M |
| State Street Corp. | 0.00% | Add +27.0% | 6,692,745 | $130.9M |
| FMR LLC | 0.01% | Add +21.6% | 6,569,921 | $128.5M |
| FCPM III Services B.V. | 14.01% | No change | 5,462,846 | $106.9M |
| Adage Capital Partners Gp, L.L.C. | 0.15% | Add +45.5% | 5,172,000 | $101.2M |
| Orbis Allan Gray Ltd | 0.39% | New | 4,801,928 | $93.9M |
| TCG Crossover Management, LLC | 2.99% | No change | 4,615,144 | $90.3M |
| JPMorgan Chase & Co. | 0.00% | Add +5.5% | 3,549,909 | $69.4M |
| Siren, L.L.C. | 2.04% | Reduce -25.9% | 3,502,941 | $68.5M |
| Perceptive Advisors LLC | 1.25% | Add +543.7% | 3,478,944 | $68.0M |
| Geode Capital Management, LLC | 0.00% | Add +13.8% | 3,263,429 | $63.8M |
| Armistice Capital, LLC | 1.56% | Add +6.1% | 3,249,708 | $63.6M |
| Frazier Life Sciences Management, L.P. | 1.66% | Add +16.0% | 3,153,082 | $61.7M |
| Deep Track Capital, LP | 1.18% | Add +32.5% | 2,650,000 | $51.8M |
| Vivo Capital, LLC | 3.31% | No change | 2,614,960 | $51.1M |
| T. Rowe Price Associates Inc. | 0.00% | Add +66.2% | 2,323,789 | $45.5M |
| Goldman Sachs Group Inc. | 0.01% | Add +20.1% | 2,283,191 | $44.7M |
| Sofinnova Investments, Inc. | 1.90% | Add +128.7% | 2,254,161 | $44.1M |
| Orbimed Advisors LLC | 0.88% | Reduce -4.8% | 2,202,184 | $43.1M |
| Venrock Adviser, LLC | 2.10% | No change | 2,173,913 | $42.5M |
| Franklin Resources Inc. | 0.01% | Add +43.5% | 2,006,638 | $39.2M |
| Saturn V Capital Management LP | 6.42% | Reduce -33.1% | 1,788,616 | $35.0M |
| Samlyn Capital, LLC | 0.47% | New | 1,493,075 | $29.2M |
| Braidwell LP | 1.11% | Reduce -45.9% | 1,478,329 | $28.9M |
| Palo Alto Investors LP | 4.01% | Add +16.6% | 1,472,197 | $28.8M |
| MPM Bioimpact LLC | 3.15% | Reduce -2.8% | 1,405,388 | $27.5M |
| Polar Capital Holdings Plc | 0.11% | Add +139.7% | 1,269,131 | $24.8M |
| Logos Global Management LP | 1.63% | Reduce -47.9% | 1,250,000 | $24.4M |
| Morgan Stanley | 0.00% | Reduce -14.5% | 1,213,559 | $23.7M |
| Citadel Advisors | 0.02% | Reduce -65.7% | 1,171,624 | $22.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +14.3% | 1,151,325 | $22.5M |
| Frontier Capital Management Co. LLC | 0.24% | Add +25.0% | 1,138,868 | $22.3M |
| Aberdeen Group plc | 0.03% | Add +99.0% | 1,108,145 | $21.7M |
| Northern Trust Corp. | 0.00% | Add +5.3% | 1,092,191 | $21.4M |
| Candriam S.C.A. | 0.10% | Add +26.8% | 1,057,263 | $20.7M |
| Rock Springs Capital Management LP | 0.92% | Add +10.8% | 912,955 | $17.9M |
| Millennium Management | 0.01% | Add +118.5% | 904,389 | $17.7M |
| Bank of America Corp. | 0.00% | Add +16.0% | 882,922 | $17.3M |
| Stempoint Capital LP | 2.80% | Add +76.0% | 835,200 | $16.3M |
| Baker Bros. Advisors LP | 0.09% | New | 813,449 | $15.9M |
| ArrowMark Colorado Holdings LLC | 0.30% | Reduce -10.8% | 700,653 | $13.7M |
| Eventide Asset Management, LLC | 0.21% | New | 680,305 | $13.3M |
| Marshall Wace, LLP | 0.01% | Reduce -77.5% | 676,979 | $13.2M |
| Artisan Partners Limited Partnership | 0.02% | New | 649,691 | $12.7M |
| Nuveen, LLC | 0.00% | Add +80.1% | 621,310 | $12.2M |
| Raymond James Financial Inc. | 0.00% | Add +589.5% | 530,338 | $10.4M |
| Catalio Capital Management, LP | 1.80% | New | 519,715 | $10.2M |
| Ensign Peak Advisors, Inc | 0.02% | Add +2364.5% | 496,590 | $9.7M |
| Renaissance Technologies | 0.01% | Add +36.2% | 470,645 | $9.2M |
| Federated Hermes, Inc. | 0.02% | New | 464,797 | $9.1M |
| Barclays PLC | 0.00% | Reduce -6.7% | 448,658 | $8.8M |
| Balyasny Asset Management L.P. | 0.02% | New | 432,986 | $8.5M |
| TD Asset Management Inc | 0.01% | Add +1959.4% | 419,756 | $8.2M |
| University of Wisconsin Foundation | 6.85% | Reduce -19.5% | 416,750 | $8.2M |
| Qube Research & Technologies Ltd | 0.01% | Reduce -50.3% | 412,440 | $8.1M |
| Clearbridge Investments, LLC | 0.01% | New | 407,794 | $8.0M |
| Wasatch Advisors LP | 0.05% | Reduce -22.3% | 406,960 | $8.0M |
| Sphera Funds Management LTD. | 1.61% | Reduce -7.9% | 392,894 | $7.7M |
| UBS Group AG | 0.00% | Add +9.0% | 380,978 | $7.5M |
| Schroder Investment Management Group | 0.01% | Add +40.4% | 386,953 | $7.4M |
| Bank of New York Mellon Corp | 0.00% | Add +11.4% | 353,497 | $6.9M |
| Y-Intercept (Hong Kong) Ltd | 0.15% | New | 343,726 | $6.7M |
| Point72 Asset Management | 0.01% | Reduce -80.8% | 329,345 | $6.4M |
| Canada Pension Plan Investment Board | 0.00% | No change | 284,000 | $5.6M |
| Algert Global LLC | 0.08% | Reduce -47.3% | 271,303 | $5.3M |
| SG Americas Securities, LLC | 0.01% | New | 265,384 | $5.2M |
| Squarepoint Ops LLC | 0.01% | Add +436.1% | 255,160 | $5.0M |
| Fisher Asset Management | 0.00% | New | 250,065 | $4.9M |
| Tetragon Partners GP Ltd | 1.02% | Add +11.1% | 247,997 | $4.9M |
| SummitTX Capital, L.P. | 0.14% | Add +83.0% | 243,276 | $4.8M |
| Neo Ivy Capital Management | 0.73% | New | 237,467 | $4.6M |
| Rafferty Asset Management, LLC | 0.02% | Add +9.7% | 233,835 | $4.6M |
| Russell Investments Group, Ltd. | 0.01% | Add +103.6% | 232,013 | $4.5M |
| Swiss National Bank | 0.00% | Add +24.8% | 222,500 | $4.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -6.5% | 214,491 | $4.2M |
| Ameriprise Financial Inc. | 0.00% | Reduce -53.2% | 197,691 | $3.9M |
| Deutsche Bank AG | 0.00% | Add +55.8% | 196,080 | $3.8M |
| PDT Partners, LLC | 0.23% | Reduce -9.1% | 182,986 | $3.6M |
| Rhumbline Advisers | 0.00% | Add +4.3% | 175,020 | $3.4M |
| American Century Companies Inc. | 0.00% | Add +436.3% | 168,304 | $3.3M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +19485.3% | 165,692 | $3.2M |
| Neuberger Berman Group LLC | 0.00% | Reduce -48.5% | 165,482 | $3.2M |
| Jain Global LLC | 0.03% | Reduce -74.8% | 162,047 | $3.2M |
| Brevan Howard Capital Management LP | 0.06% | Add +166.4% | 157,969 | $3.1M |
| First Light Asset Management, LLC | 0.23% | New | 155,231 | $3.0M |
| Burkehill Global Management, LP | 0.21% | Add +29.2% | 155,000 | $3.0M |
| Lisanti Capital Growth, LLC | 0.72% | New | 154,445 | $3.0M |
| Wells Fargo & Company | 0.00% | Add +69.7% | 147,831 | $2.9M |
| Tudor Investment Corporation | 0.02% | New | 147,621 | $2.9M |
| Invesco Ltd. | 0.00% | Add +17.1% | 137,684 | $2.7M |
| Alliancebernstein L.P. | 0.00% | Add +25.9% | 134,260 | $2.6M |
| California State Teachers Retirement System | 0.00% | Add +35.5% | 120,800 | $2.4M |
| Woodline Partners LP | 0.01% | New | 120,788 | $2.4M |
| Vestal Point Capital, LP | 0.09% | Reduce -95.7% | 120,000 | $2.3M |
| Legal & General Group Plc | 0.00% | Add +9.4% | 118,122 | $2.3M |
| Darwin Wealth Management, LLC | 0.70% | Reduce -33.6% | 115,267 | $2.3M |
"% of holder's portfolio" is DYN's weight in each manager's 13F, not the share of Dyne Therapeutics Inc. the manager owns.