Dyne TherapeuticsDYN
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 233 institutions reported holding Dyne Therapeutics Inc. (DYN) in their 13F filings, up 26 from Q3 2025. 51 opened new positions and 28 sold out. The largest holders were T. Rowe Price Investment Management, Inc. ($343.1M), Janus Henderson Group PLC ($271.6M) and Vanguard Group Inc. ($219.4M). 7 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Dyne Therapeutics Inc.
- CUSIP
- 26818M108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 51 | $254.6M |
| Exits | 28 | $113.0M |
All 13F filers, Q3 2025 → Q4 2025: 49,587,220 shares bought and 26,759,094 shares sold, net +22,828,126 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 233 holders
| T. Rowe Price Investment Management, Inc. | 0.22% | Add +523.7% | 17,540,089 | $343.1M |
| Janus Henderson Group PLC | 0.12% | Reduce -5.8% | 13,887,722 | $271.6M |
| Vanguard Group Inc. | 0.00% | Add +14.9% | 11,215,565 | $219.4M |
| BlackRock, Inc. | 0.00% | Add +16.1% | 11,190,838 | $218.9M |
| Atlas Venture Life Science Advisors, LLC | 20.64% | No change | 9,130,465 | $178.6M |
| State Street Corp. | 0.00% | Add +27.0% | 6,692,745 | $130.9M |
| FMR LLC | 0.01% | Add +21.6% | 6,569,921 | $128.5M |
| FCPM III Services B.V. | 14.01% | No change | 5,462,846 | $106.9M |
| Adage Capital Partners Gp, L.L.C. | 0.15% | Add +45.5% | 5,172,000 | $101.2M |
| Orbis Allan Gray Ltd | 0.39% | New | 4,801,928 | $93.9M |
| TCG Crossover Management, LLC | 2.99% | No change | 4,615,144 | $90.3M |
| JPMorgan Chase & Co. | 0.00% | Add +5.5% | 3,549,909 | $69.4M |
| Siren, L.L.C. | 2.04% | Reduce -25.9% | 3,502,941 | $68.5M |
| Perceptive Advisors LLC | 1.25% | Add +543.7% | 3,478,944 | $68.0M |
| Geode Capital Management, LLC | 0.00% | Add +13.8% | 3,263,429 | $63.8M |
| Armistice Capital, LLC | 1.56% | Add +6.1% | 3,249,708 | $63.6M |
| Frazier Life Sciences Management, L.P. | 1.66% | Add +16.0% | 3,153,082 | $61.7M |
| Deep Track Capital, LP | 1.18% | Add +32.5% | 2,650,000 | $51.8M |
| Vivo Capital, LLC | 3.31% | No change | 2,614,960 | $51.1M |
| T. Rowe Price Associates Inc. | 0.00% | Add +66.2% | 2,323,789 | $45.5M |
| Goldman Sachs Group Inc. | 0.01% | Add +20.1% | 2,283,191 | $44.7M |
| Sofinnova Investments, Inc. | 1.90% | Add +128.7% | 2,254,161 | $44.1M |
| Orbimed Advisors LLC | 0.88% | Reduce -4.8% | 2,202,184 | $43.1M |
| Venrock Adviser, LLC | 2.10% | No change | 2,173,913 | $42.5M |
| Franklin Resources Inc. | 0.01% | Add +43.5% | 2,006,638 | $39.2M |
| Saturn V Capital Management LP | 6.42% | Reduce -33.1% | 1,788,616 | $35.0M |
| Samlyn Capital, LLC | 0.47% | New | 1,493,075 | $29.2M |
| Braidwell LP | 1.11% | Reduce -45.9% | 1,478,329 | $28.9M |
| Palo Alto Investors LP | 4.01% | Add +16.6% | 1,472,197 | $28.8M |
| MPM Bioimpact LLC | 3.15% | Reduce -2.8% | 1,405,388 | $27.5M |
| Polar Capital Holdings Plc | 0.11% | Add +139.7% | 1,269,131 | $24.8M |
| Logos Global Management LP | 1.63% | Reduce -47.9% | 1,250,000 | $24.4M |
| Morgan Stanley | 0.00% | Reduce -14.5% | 1,213,559 | $23.7M |
| Citadel Advisors | 0.02% | Reduce -65.7% | 1,171,624 | $22.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +14.3% | 1,151,325 | $22.5M |
| Frontier Capital Management Co. LLC | 0.24% | Add +25.0% | 1,138,868 | $22.3M |
| Aberdeen Group plc | 0.03% | Add +99.0% | 1,108,145 | $21.7M |
| Northern Trust Corp. | 0.00% | Add +5.3% | 1,092,191 | $21.4M |
| Candriam S.C.A. | 0.10% | Add +26.8% | 1,057,263 | $20.7M |
| Rock Springs Capital Management LP | 0.92% | Add +10.8% | 912,955 | $17.9M |
| Millennium Management | 0.01% | Add +118.5% | 904,389 | $17.7M |
| Bank of America Corp. | 0.00% | Add +16.0% | 882,922 | $17.3M |
| Stempoint Capital LP | 2.80% | Add +76.0% | 835,200 | $16.3M |
| Baker Bros. Advisors LP | 0.09% | New | 813,449 | $15.9M |
| ArrowMark Colorado Holdings LLC | 0.30% | Reduce -10.8% | 700,653 | $13.7M |
| Eventide Asset Management, LLC | 0.21% | New | 680,305 | $13.3M |
| Marshall Wace, LLP | 0.01% | Reduce -77.5% | 676,979 | $13.2M |
| Artisan Partners Limited Partnership | 0.02% | New | 649,691 | $12.7M |
| Nuveen, LLC | 0.00% | Add +80.1% | 621,310 | $12.2M |
| Raymond James Financial Inc. | 0.00% | Add +589.5% | 530,338 | $10.4M |
| Catalio Capital Management, LP | 1.80% | New | 519,715 | $10.2M |
| Ensign Peak Advisors, Inc | 0.02% | Add +2364.5% | 496,590 | $9.7M |
| Renaissance Technologies | 0.01% | Add +36.2% | 470,645 | $9.2M |
| Federated Hermes, Inc. | 0.02% | New | 464,797 | $9.1M |
| Barclays PLC | 0.00% | Reduce -6.7% | 448,658 | $8.8M |
| Balyasny Asset Management L.P. | 0.02% | New | 432,986 | $8.5M |
| TD Asset Management Inc | 0.01% | Add +1959.4% | 419,756 | $8.2M |
| University of Wisconsin Foundation | 6.85% | Reduce -19.5% | 416,750 | $8.2M |
| Qube Research & Technologies Ltd | 0.01% | Reduce -50.3% | 412,440 | $8.1M |
| Clearbridge Investments, LLC | 0.01% | New | 407,794 | $8.0M |
| Wasatch Advisors LP | 0.05% | Reduce -22.3% | 406,960 | $8.0M |
| Sphera Funds Management LTD. | 1.61% | Reduce -7.9% | 392,894 | $7.7M |
| UBS Group AG | 0.00% | Add +9.0% | 380,978 | $7.5M |
| Schroder Investment Management Group | 0.01% | Add +40.4% | 386,953 | $7.4M |
| Bank of New York Mellon Corp | 0.00% | Add +11.4% | 353,497 | $6.9M |
| Y-Intercept (Hong Kong) Ltd | 0.15% | New | 343,726 | $6.7M |
| Point72 Asset Management | 0.01% | Reduce -80.8% | 329,345 | $6.4M |
| Canada Pension Plan Investment Board | 0.00% | No change | 284,000 | $5.6M |
| Algert Global LLC | 0.08% | Reduce -47.3% | 271,303 | $5.3M |
| SG Americas Securities, LLC | 0.01% | New | 265,384 | $5.2M |
| Squarepoint Ops LLC | 0.01% | Add +436.1% | 255,160 | $5.0M |
| Fisher Asset Management | 0.00% | New | 250,065 | $4.9M |
| Tetragon Partners GP Ltd | 1.02% | Add +11.1% | 247,997 | $4.9M |
| SummitTX Capital, L.P. | 0.14% | Add +83.0% | 243,276 | $4.8M |
| Neo Ivy Capital Management | 0.73% | New | 237,467 | $4.6M |
| Rafferty Asset Management, LLC | 0.02% | Add +9.7% | 233,835 | $4.6M |
| Russell Investments Group, Ltd. | 0.01% | Add +103.6% | 232,013 | $4.5M |
| Swiss National Bank | 0.00% | Add +24.8% | 222,500 | $4.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -6.5% | 214,491 | $4.2M |
| Ameriprise Financial Inc. | 0.00% | Reduce -53.2% | 197,691 | $3.9M |
| Deutsche Bank AG | 0.00% | Add +55.8% | 196,080 | $3.8M |
| PDT Partners, LLC | 0.23% | Reduce -9.1% | 182,986 | $3.6M |
| Rhumbline Advisers | 0.00% | Add +4.3% | 175,020 | $3.4M |
| American Century Companies Inc. | 0.00% | Add +436.3% | 168,304 | $3.3M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +19485.3% | 165,692 | $3.2M |
| Neuberger Berman Group LLC | 0.00% | Reduce -48.5% | 165,482 | $3.2M |
| Jain Global LLC | 0.03% | Reduce -74.8% | 162,047 | $3.2M |
| Brevan Howard Capital Management LP | 0.06% | Add +166.4% | 157,969 | $3.1M |
| First Light Asset Management, LLC | 0.23% | New | 155,231 | $3.0M |
| Burkehill Global Management, LP | 0.21% | Add +29.2% | 155,000 | $3.0M |
| Lisanti Capital Growth, LLC | 0.72% | New | 154,445 | $3.0M |
| Wells Fargo & Company | 0.00% | Add +69.7% | 147,831 | $2.9M |
| Tudor Investment Corporation | 0.02% | New | 147,621 | $2.9M |
| Invesco Ltd. | 0.00% | Add +17.1% | 137,684 | $2.7M |
| Alliancebernstein L.P. | 0.00% | Add +25.9% | 134,260 | $2.6M |
| California State Teachers Retirement System | 0.00% | Add +35.5% | 120,800 | $2.4M |
| Woodline Partners LP | 0.01% | New | 120,788 | $2.4M |
| Vestal Point Capital, LP | 0.09% | Reduce -95.7% | 120,000 | $2.3M |
| Legal & General Group Plc | 0.00% | Add +9.4% | 118,122 | $2.3M |
| Darwin Wealth Management, LLC | 0.70% | Reduce -33.6% | 115,267 | $2.3M |
| Monashee Investment Management LLC | 1.32% | New | 114,525 | $2.2M |
| Axxcess Wealth Management, LLC | 0.04% | New | 113,818 | $2.2M |
| Baird Financial Group, Inc. | 0.00% | New | 103,334 | $2.0M |
| Trexquant Investment LP | 0.02% | Reduce -70.9% | 100,645 | $2.0M |
| Susquehanna International Group, LLP | 0.00% | Reduce -16.6% | 98,215 | $1.9M |
| Dimensional Fund Advisors LP | 0.00% | New | 98,074 | $1.9M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 60,000 | $1.9M |
| Profund Advisors LLC | 0.05% | Add +88.7% | 86,746 | $1.7M |
| Voya Investment Management LLC | 0.00% | Reduce -12.4% | 86,438 | $1.7M |
| Comerica Bank | 0.01% | Reduce -1.3% | 85,339 | $1.7M |
| New York State Common Retirement Fund | 0.00% | Add +128.6% | 79,262 | $1.6M |
| Aegis Wealth Management LLC | 0.84% | Add +52.1% | 75,908 | $1.5M |
| HRT Financial LP | 0.00% | New | 75,394 | $1.5M |
| Headlands Technologies LLC | 0.12% | Add +492.4% | 75,235 | $1.5M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +15.5% | 71,191 | $1.4M |
| AQR Capital Management | 0.00% | Reduce -50.2% | 70,659 | $1.4M |
| Jane Street Group, LLC | 0.00% | Reduce -75.0% | 70,323 | $1.4M |
| Seven Fleet Capital Management LP | 0.93% | — | 70,180 | $1.4M |
| MetLife Investment Management, LLC | 0.01% | Add +8.4% | 69,599 | $1.4M |
| Cibc World Market Inc. | 0.00% | New | 68,766 | $1.3M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +17.7% | 67,507 | $1.3M |
| State of Wisconsin Investment Board | 0.00% | Add +59.3% | 63,653 | $1.2M |
| HighVista Strategies LLC | 0.30% | New | 59,643 | $1.2M |
| Sei Investments Co. | 0.00% | New | 58,755 | $1.1M |
| XTX Topco Ltd | 0.03% | Add +93.9% | 56,661 | $1.1M |
| Victory Capital Management Inc. | 0.00% | Add +2.8% | 51,484 | $1.0M |
| Norges Bank | 0.00% | — | 49,319 | $965K |
| Arcadia Investment Management Corp. | 0.15% | Reduce -2.7% | 47,875 | $936K |
| Wellington Management Group LLP | 0.00% | Add +12.4% | 47,096 | $921K |
| J. Goldman & Co LP | 0.04% | New | 46,010 | $900K |
| Intech Investment Management LLC | 0.01% | Reduce -16.5% | 44,288 | $866K |
| ADAR1 Capital Management, LLC | 0.06% | Add +13.3% | 42,674 | $835K |
| Legato Capital Management LLC | 0.07% | New | 42,665 | $835K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +12.0% | 37,307 | $730K |
| Citigroup Inc. | 0.00% | Add +9.8% | 36,657 | $717K |
| Graham Capital Management, L.P. | 0.03% | Reduce -16.2% | 36,167 | $707K |
| Jump Financial, LLC | 0.01% | Reduce -64.7% | 35,260 | $690K |
| Seven Grand Managers, LLC | 0.05% | New | 35,000 | $685K |
| Lighthouse Investment Partners, LLC | 0.02% | Add +70.0% | 34,000 | $665K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Add +12.1% | 33,547 | $656K |
| State of New Jersey Common Pension Fund D | 0.00% | New | 31,562 | $617K |
| Gsa Capital Partners LLP | 0.05% | Reduce -10.7% | 31,422 | $615K |
| Arizona State Retirement System | 0.00% | Add +15.5% | 31,416 | $614K |
| Optimize Financial Inc. | 0.30% | Add +1.5% | 30,310 | $593K |
| ProShare Advisors LLC | 0.00% | Add +21.8% | 28,926 | $566K |
| Walleye Capital LLC | 0.00% | New | 27,762 | $543K |
| KLP Kapitalforvaltning As | 0.00% | Add +28.3% | 25,400 | $497K |
| Martingale Asset Management L P | 0.01% | Reduce -7.0% | 25,152 | $492K |
| BNP Paribas Financial Markets | 0.00% | Reduce -82.0% | 24,506 | $479K |
| Elevate Capital Advisors, LLC | 0.31% | New | 24,114 | $472K |
| China Universal Asset Management Co., Ltd. | 0.04% | Reduce -6.7% | 23,273 | $455K |
| Engineers Gate Manager LP | 0.01% | Reduce -79.0% | 21,619 | $423K |
| PSP Research LLC | 0.37% | — | 21,535 | $421K |
| WINTON GROUP Ltd | 0.01% | Reduce -72.7% | 21,296 | $417K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 20,605 | $403K |
| Creative Planning | 0.00% | Add +27.3% | 19,771 | $387K |
| Royal Bank of Canada | 0.00% | Reduce -96.6% | 18,547 | $363K |
| Lion Point Capital, LP | 1.82% | New | 18,000 | $352K |
| Los Angeles Capital Management LLC | 0.00% | New | 13,692 | $322K |
| Fox Run Management, L.L.C. | 0.05% | New | 16,450 | $322K |
| Teacher Retirement System of Texas | 0.00% | Reduce -28.4% | 16,074 | $314K |
| AlphaQuest LLC | 0.02% | Add +8.9% | 15,963 | $312K |
| LPL Financial LLC | 0.00% | New | 15,250 | $298K |
| Z3 Capital Partners, LLC | 0.07% | — | 15,050 | $294K |
| BIT Capital GmbH | 0.01% | New | 15,000 | $293K |
| Allianz Asset Management GmbH | 0.00% | New | 15,000 | $293K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | New | 14,399 | $282K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.04% | New | 14,383 | $281K |
| Thrivent Financial for Lutherans | 0.00% | No change | 14,365 | $281K |
| Rockefeller Capital Management L.P. | 0.00% | Add +67.1% | 14,268 | $279K |
| Virtus Investment Advisers, LLC | 0.07% | Add +75.5% | 13,806 | $270K |
| Pictet Asset Management Holding SA | 0.00% | New | 12,963 | $254K |
| Capstone Investment Advisors, LLC | 0.00% | New | 12,700 | $248K |
| Quantinno Capital Management LP | 0.00% | Add +2.1% | 12,593 | $246K |
| Bridgefront Capital, LLC | 0.06% | Reduce -33.4% | 12,018 | $235K |
| Guggenheim Capital LLC | 0.00% | Reduce -76.8% | 11,071 | $217K |
| Nisa Investment Advisors, LLC | 0.00% | Add +1006.3% | 10,499 | $205K |
| Verition Fund Management LLC | 0.00% | New | 10,453 | $204K |
| Ameritas Investment Partners, Inc. | 0.01% | Add +9.0% | 10,442 | $204K |
| Soleus Capital Management, L.P. | 0.01% | New | 10,000 | $196K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 10,000 | $196K |
| Simplex Trading, LLC | 0.01% | Reduce -38.1% | 9,186 | $180K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +26.2% | 6,940 | $136K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 5,740 | $112K |
| Sterling Capital Management LLC | 0.00% | Reduce -0.9% | 5,166 | $101K |
| Keating Financial Advisory Services, Inc. | 0.01% | — | 5,000 | $98K |
| Steward Partners Investment Advisory, LLC | 0.00% | Add +102.1% | 4,880 | $95K |
| Aster Capital Management (DIFC) Ltd | 0.04% | New | 4,310 | $84K |
| Cwm, LLC | 0.00% | Add +14.9% | 4,028 | $79K |
| Amalgamated Bank | 0.00% | Add +38.8% | 3,889 | $76K |
| KBC Group NV | 0.00% | No change | 3,135 | $61K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -8.3% | 2,806 | $55K |
| Chung Wu Investment Group, LLC | 0.04% | Add +16.7% | 2,800 | $55K |
| STRS Ohio | 0.00% | New | 2,600 | $51K |
| Caption Management, LLC | 0.00% | New | 2,500 | $49K |
| Jones Financial Companies LLLP | 0.00% | No change | 1,199 | $23K |
| Versant Capital Management, Inc | 0.00% | No change | 859 | $17K |
| GAMMA Investing LLC | 0.00% | Add +29.6% | 841 | $16K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -91.0% | 730 | $14K |
| Group One Trading LLC | 0.00% | Reduce -66.8% | 650 | $13K |
| Osaic Holdings, Inc. | 0.00% | Reduce -0.9% | 635 | $12K |
| Allworth Financial LP | 0.00% | Add +12.9% | 559 | $11K |
| Smartleaf Asset Management LLC | 0.00% | Add +568.7% | 555 | $11K |
| Essential Partners LLC | 0.00% | Add +1.4% | 445 | $9K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -9.1% | 418 | $8K |
| Daiwa Securities Group Inc. | 0.00% | Add +14.3% | 424 | $8K |
| US Bancorp \de | 0.00% | Add +10.8% | 400 | $8K |
| Optiver Holding B.V. | 0.00% | Reduce -56.3% | 395 | $8K |
| First Horizon Corp. | 0.00% | Reduce -2.0% | 382 | $7K |
| Signaturefd, LLC | 0.00% | Add +15.1% | 320 | $6K |
| Truvestments Capital LLC | 0.00% | No change | 295 | $6K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 243 | $5K |
| Aspect Partners, LLC | 0.00% | Reduce -62.8% | 225 | $4K |
| Flagship Harbor Advisors, LLC | 0.00% | New | 200 | $4K |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 0.00% | — | 200 | $4K |
| National Bank of Canada | 0.00% | Add +33.3% | 200 | $4K |
| Rothschild Investment LLC | 0.00% | Add +3.0% | 170 | $3K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -6.3% | 150 | $3K |
| Geneos Wealth Management Inc. | 0.00% | New | 138 | $3K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 97 | $2K |
| IFP Advisors, Inc | 0.00% | Reduce -1.0% | 95 | $2K |
| MRP Capital Investments, LLC | 0.00% | New | 75 | $1K |
| Parkside Financial Bank & Trust | 0.00% | Add +75.0% | 70 | $1K |
| Quadrant Capital Group LLC | 0.00% | No change | 67 | $1K |
| Basecamp Wealth Advisors LLC | 0.00% | — | 42 | $822 |
| Cornerstone Financial Management LLC | 0.00% | — | 40 | $782 |
| Parallel Advisors, LLC | 0.00% | No change | 27 | $528 |
| Bell Investment Advisors, Inc | 0.00% | New | 26 | $509 |
| Larson Financial Group LLC | 0.00% | Add +15.8% | 22 | $430 |
| Arax Advisory Partners | 0.00% | Reduce -96.3% | 18 | $352 |
| Farther Finance Advisors, LLC | 0.00% | Add +13.3% | 17 | $333 |
| True Wealth Design, LLC | 0.00% | No change | 13 | $255 |
| Dunhill Financial, LLC | 0.00% | New | 1 | $17 |
"% of holder's portfolio" is DYN's weight in each manager's 13F, not the share of Dyne Therapeutics Inc. the manager owns.