Dyne TherapeuticsDYN

13F holders, Q4 2025 (December 31)
233holders +26
51new positions
28sold out
7famous investors
$19.56avg. 13F price*

At the end of Q4 2025, 233 institutions reported holding Dyne Therapeutics Inc. (DYN) in their 13F filings, up 26 from Q3 2025. 51 opened new positions and 28 sold out. The largest holders were T. Rowe Price Investment Management, Inc. ($343.1M), Janus Henderson Group PLC ($271.6M) and Vanguard Group Inc. ($219.4M). 7 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Dyne Therapeutics Inc.
CUSIP
26818M108
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 169Q1 2024Q2 2024: 193Q2 2024Q3 2024: 200Q3 2024Q4 2024: 200Q4 2024Q1 2025: 205Q1 2025Q2 2025: 197Q2 2025Q3 2025: 207Q3 2025Q4 2025: 233Q4 2025Q1 2026: 228Q1 2026Q2 2026: 245Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions51$254.6M
Exits28$113.0M

All 13F filers, Q3 2025 → Q4 2025: 49,587,220 shares bought and 26,759,094 shares sold, net +22,828,126 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 233 holders

T. Rowe Price Investment Management, Inc. 0.22% Add +523.7% 17,540,089 $343.1M
Janus Henderson Group PLC 0.12% Reduce -5.8% 13,887,722 $271.6M
Vanguard Group Inc. 0.00% Add +14.9% 11,215,565 $219.4M
BlackRock, Inc. 0.00% Add +16.1% 11,190,838 $218.9M
Atlas Venture Life Science Advisors, LLC 20.64% No change 9,130,465 $178.6M
State Street Corp. 0.00% Add +27.0% 6,692,745 $130.9M
FMR LLC 0.01% Add +21.6% 6,569,921 $128.5M
FCPM III Services B.V. 14.01% No change 5,462,846 $106.9M
Adage Capital Partners Gp, L.L.C. 0.15% Add +45.5% 5,172,000 $101.2M
Orbis Allan Gray Ltd 0.39% New 4,801,928 $93.9M
TCG Crossover Management, LLC 2.99% No change 4,615,144 $90.3M
JPMorgan Chase & Co. 0.00% Add +5.5% 3,549,909 $69.4M
Siren, L.L.C. 2.04% Reduce -25.9% 3,502,941 $68.5M
Perceptive Advisors LLC 1.25% Add +543.7% 3,478,944 $68.0M
Geode Capital Management, LLC 0.00% Add +13.8% 3,263,429 $63.8M
Armistice Capital, LLC 1.56% Add +6.1% 3,249,708 $63.6M
Frazier Life Sciences Management, L.P. 1.66% Add +16.0% 3,153,082 $61.7M
Deep Track Capital, LP 1.18% Add +32.5% 2,650,000 $51.8M
Vivo Capital, LLC 3.31% No change 2,614,960 $51.1M
T. Rowe Price Associates Inc. 0.00% Add +66.2% 2,323,789 $45.5M
Goldman Sachs Group Inc. 0.01% Add +20.1% 2,283,191 $44.7M
Sofinnova Investments, Inc. 1.90% Add +128.7% 2,254,161 $44.1M
Orbimed Advisors LLC 0.88% Reduce -4.8% 2,202,184 $43.1M
Venrock Adviser, LLC 2.10% No change 2,173,913 $42.5M
Franklin Resources Inc. 0.01% Add +43.5% 2,006,638 $39.2M
Saturn V Capital Management LP 6.42% Reduce -33.1% 1,788,616 $35.0M
Samlyn Capital, LLC 0.47% New 1,493,075 $29.2M
Braidwell LP 1.11% Reduce -45.9% 1,478,329 $28.9M
Palo Alto Investors LP 4.01% Add +16.6% 1,472,197 $28.8M
MPM Bioimpact LLC 3.15% Reduce -2.8% 1,405,388 $27.5M
Polar Capital Holdings Plc 0.11% Add +139.7% 1,269,131 $24.8M
Logos Global Management LP 1.63% Reduce -47.9% 1,250,000 $24.4M
Morgan Stanley 0.00% Reduce -14.5% 1,213,559 $23.7M
Citadel Advisors 0.02% Reduce -65.7% 1,171,624 $22.9M
Charles Schwab Investment Management Inc. 0.00% Add +14.3% 1,151,325 $22.5M
Frontier Capital Management Co. LLC 0.24% Add +25.0% 1,138,868 $22.3M
Aberdeen Group plc 0.03% Add +99.0% 1,108,145 $21.7M
Northern Trust Corp. 0.00% Add +5.3% 1,092,191 $21.4M
Candriam S.C.A. 0.10% Add +26.8% 1,057,263 $20.7M
Rock Springs Capital Management LP 0.92% Add +10.8% 912,955 $17.9M
Millennium Management 0.01% Add +118.5% 904,389 $17.7M
Bank of America Corp. 0.00% Add +16.0% 882,922 $17.3M
Stempoint Capital LP 2.80% Add +76.0% 835,200 $16.3M
Baker Bros. Advisors LP 0.09% New 813,449 $15.9M
ArrowMark Colorado Holdings LLC 0.30% Reduce -10.8% 700,653 $13.7M
Eventide Asset Management, LLC 0.21% New 680,305 $13.3M
Marshall Wace, LLP 0.01% Reduce -77.5% 676,979 $13.2M
Artisan Partners Limited Partnership 0.02% New 649,691 $12.7M
Nuveen, LLC 0.00% Add +80.1% 621,310 $12.2M
Raymond James Financial Inc. 0.00% Add +589.5% 530,338 $10.4M
Catalio Capital Management, LP 1.80% New 519,715 $10.2M
Ensign Peak Advisors, Inc 0.02% Add +2364.5% 496,590 $9.7M
Renaissance Technologies 0.01% Add +36.2% 470,645 $9.2M
Federated Hermes, Inc. 0.02% New 464,797 $9.1M
Barclays PLC 0.00% Reduce -6.7% 448,658 $8.8M
Balyasny Asset Management L.P. 0.02% New 432,986 $8.5M
TD Asset Management Inc 0.01% Add +1959.4% 419,756 $8.2M
University of Wisconsin Foundation 6.85% Reduce -19.5% 416,750 $8.2M
Qube Research & Technologies Ltd 0.01% Reduce -50.3% 412,440 $8.1M
Clearbridge Investments, LLC 0.01% New 407,794 $8.0M
Wasatch Advisors LP 0.05% Reduce -22.3% 406,960 $8.0M
Sphera Funds Management LTD. 1.61% Reduce -7.9% 392,894 $7.7M
UBS Group AG 0.00% Add +9.0% 380,978 $7.5M
Schroder Investment Management Group 0.01% Add +40.4% 386,953 $7.4M
Bank of New York Mellon Corp 0.00% Add +11.4% 353,497 $6.9M
Y-Intercept (Hong Kong) Ltd 0.15% New 343,726 $6.7M
Point72 Asset Management 0.01% Reduce -80.8% 329,345 $6.4M
Canada Pension Plan Investment Board 0.00% No change 284,000 $5.6M
Algert Global LLC 0.08% Reduce -47.3% 271,303 $5.3M
SG Americas Securities, LLC 0.01% New 265,384 $5.2M
Squarepoint Ops LLC 0.01% Add +436.1% 255,160 $5.0M
Fisher Asset Management 0.00% New 250,065 $4.9M
Tetragon Partners GP Ltd 1.02% Add +11.1% 247,997 $4.9M
SummitTX Capital, L.P. 0.14% Add +83.0% 243,276 $4.8M
Neo Ivy Capital Management 0.73% New 237,467 $4.6M
Rafferty Asset Management, LLC 0.02% Add +9.7% 233,835 $4.6M
Russell Investments Group, Ltd. 0.01% Add +103.6% 232,013 $4.5M
Swiss National Bank 0.00% Add +24.8% 222,500 $4.4M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -6.5% 214,491 $4.2M
Ameriprise Financial Inc. 0.00% Reduce -53.2% 197,691 $3.9M
Deutsche Bank AG 0.00% Add +55.8% 196,080 $3.8M
PDT Partners, LLC 0.23% Reduce -9.1% 182,986 $3.6M
Rhumbline Advisers 0.00% Add +4.3% 175,020 $3.4M
American Century Companies Inc. 0.00% Add +436.3% 168,304 $3.3M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Add +19485.3% 165,692 $3.2M
Neuberger Berman Group LLC 0.00% Reduce -48.5% 165,482 $3.2M
Jain Global LLC 0.03% Reduce -74.8% 162,047 $3.2M
Brevan Howard Capital Management LP 0.06% Add +166.4% 157,969 $3.1M
First Light Asset Management, LLC 0.23% New 155,231 $3.0M
Burkehill Global Management, LP 0.21% Add +29.2% 155,000 $3.0M
Lisanti Capital Growth, LLC 0.72% New 154,445 $3.0M
Wells Fargo & Company 0.00% Add +69.7% 147,831 $2.9M
Tudor Investment Corporation 0.02% New 147,621 $2.9M
Invesco Ltd. 0.00% Add +17.1% 137,684 $2.7M
Alliancebernstein L.P. 0.00% Add +25.9% 134,260 $2.6M
California State Teachers Retirement System 0.00% Add +35.5% 120,800 $2.4M
Woodline Partners LP 0.01% New 120,788 $2.4M
Vestal Point Capital, LP 0.09% Reduce -95.7% 120,000 $2.3M
Legal & General Group Plc 0.00% Add +9.4% 118,122 $2.3M
Darwin Wealth Management, LLC 0.70% Reduce -33.6% 115,267 $2.3M
Monashee Investment Management LLC 1.32% New 114,525 $2.2M
Axxcess Wealth Management, LLC 0.04% New 113,818 $2.2M
Baird Financial Group, Inc. 0.00% New 103,334 $2.0M
Trexquant Investment LP 0.02% Reduce -70.9% 100,645 $2.0M
Susquehanna International Group, LLP 0.00% Reduce -16.6% 98,215 $1.9M
Dimensional Fund Advisors LP 0.00% New 98,074 $1.9M
DekaBank Deutsche Girozentrale 0.00% No change 60,000 $1.9M
Profund Advisors LLC 0.05% Add +88.7% 86,746 $1.7M
Voya Investment Management LLC 0.00% Reduce -12.4% 86,438 $1.7M
Comerica Bank 0.01% Reduce -1.3% 85,339 $1.7M
New York State Common Retirement Fund 0.00% Add +128.6% 79,262 $1.6M
Aegis Wealth Management LLC 0.84% Add +52.1% 75,908 $1.5M
HRT Financial LP 0.00% New 75,394 $1.5M
Headlands Technologies LLC 0.12% Add +492.4% 75,235 $1.5M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +15.5% 71,191 $1.4M
AQR Capital Management 0.00% Reduce -50.2% 70,659 $1.4M
Jane Street Group, LLC 0.00% Reduce -75.0% 70,323 $1.4M
Seven Fleet Capital Management LP 0.93% — 70,180 $1.4M
MetLife Investment Management, LLC 0.01% Add +8.4% 69,599 $1.4M
Cibc World Market Inc. 0.00% New 68,766 $1.3M
Manufacturers Life Insurance Company, The 0.00% Add +17.7% 67,507 $1.3M
State of Wisconsin Investment Board 0.00% Add +59.3% 63,653 $1.2M
HighVista Strategies LLC 0.30% New 59,643 $1.2M
Sei Investments Co. 0.00% New 58,755 $1.1M
XTX Topco Ltd 0.03% Add +93.9% 56,661 $1.1M
Victory Capital Management Inc. 0.00% Add +2.8% 51,484 $1.0M
Norges Bank 0.00% — 49,319 $965K
Arcadia Investment Management Corp. 0.15% Reduce -2.7% 47,875 $936K
Wellington Management Group LLP 0.00% Add +12.4% 47,096 $921K
J. Goldman & Co LP 0.04% New 46,010 $900K
Intech Investment Management LLC 0.01% Reduce -16.5% 44,288 $866K
ADAR1 Capital Management, LLC 0.06% Add +13.3% 42,674 $835K
Legato Capital Management LLC 0.07% New 42,665 $835K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +12.0% 37,307 $730K
Citigroup Inc. 0.00% Add +9.8% 36,657 $717K
Graham Capital Management, L.P. 0.03% Reduce -16.2% 36,167 $707K
Jump Financial, LLC 0.01% Reduce -64.7% 35,260 $690K
Seven Grand Managers, LLC 0.05% New 35,000 $685K
Lighthouse Investment Partners, LLC 0.02% Add +70.0% 34,000 $665K
Police & Firemen's Retirement System of New Jersey 0.01% Add +12.1% 33,547 $656K
State of New Jersey Common Pension Fund D 0.00% New 31,562 $617K
Gsa Capital Partners LLP 0.05% Reduce -10.7% 31,422 $615K
Arizona State Retirement System 0.00% Add +15.5% 31,416 $614K
Optimize Financial Inc. 0.30% Add +1.5% 30,310 $593K
ProShare Advisors LLC 0.00% Add +21.8% 28,926 $566K
Walleye Capital LLC 0.00% New 27,762 $543K
KLP Kapitalforvaltning As 0.00% Add +28.3% 25,400 $497K
Martingale Asset Management L P 0.01% Reduce -7.0% 25,152 $492K
BNP Paribas Financial Markets 0.00% Reduce -82.0% 24,506 $479K
Elevate Capital Advisors, LLC 0.31% New 24,114 $472K
China Universal Asset Management Co., Ltd. 0.04% Reduce -6.7% 23,273 $455K
Engineers Gate Manager LP 0.01% Reduce -79.0% 21,619 $423K
PSP Research LLC 0.37% — 21,535 $421K
WINTON GROUP Ltd 0.01% Reduce -72.7% 21,296 $417K
State Board of Administration of Florida Retirement System 0.00% No change 20,605 $403K
Creative Planning 0.00% Add +27.3% 19,771 $387K
Royal Bank of Canada 0.00% Reduce -96.6% 18,547 $363K
Lion Point Capital, LP 1.82% New 18,000 $352K
Los Angeles Capital Management LLC 0.00% New 13,692 $322K
Fox Run Management, L.L.C. 0.05% New 16,450 $322K
Teacher Retirement System of Texas 0.00% Reduce -28.4% 16,074 $314K
AlphaQuest LLC 0.02% Add +8.9% 15,963 $312K
LPL Financial LLC 0.00% New 15,250 $298K
Z3 Capital Partners, LLC 0.07% — 15,050 $294K
BIT Capital GmbH 0.01% New 15,000 $293K
Allianz Asset Management GmbH 0.00% New 15,000 $293K
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% New 14,399 $282K
Arrowpoint Investment Partners (Singapore) Pte. Ltd. 0.04% New 14,383 $281K
Thrivent Financial for Lutherans 0.00% No change 14,365 $281K
Rockefeller Capital Management L.P. 0.00% Add +67.1% 14,268 $279K
Virtus Investment Advisers, LLC 0.07% Add +75.5% 13,806 $270K
Pictet Asset Management Holding SA 0.00% New 12,963 $254K
Capstone Investment Advisors, LLC 0.00% New 12,700 $248K
Quantinno Capital Management LP 0.00% Add +2.1% 12,593 $246K
Bridgefront Capital, LLC 0.06% Reduce -33.4% 12,018 $235K
Guggenheim Capital LLC 0.00% Reduce -76.8% 11,071 $217K
Nisa Investment Advisors, LLC 0.00% Add +1006.3% 10,499 $205K
Verition Fund Management LLC 0.00% New 10,453 $204K
Ameritas Investment Partners, Inc. 0.01% Add +9.0% 10,442 $204K
Soleus Capital Management, L.P. 0.01% New 10,000 $196K
Farallon Capital Management, L.L.C. 0.00% No change 10,000 $196K
Simplex Trading, LLC 0.01% Reduce -38.1% 9,186 $180K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +26.2% 6,940 $136K
Public Employees Retirement Association of Colorado 0.00% No change 5,740 $112K
Sterling Capital Management LLC 0.00% Reduce -0.9% 5,166 $101K
Keating Financial Advisory Services, Inc. 0.01% — 5,000 $98K
Steward Partners Investment Advisory, LLC 0.00% Add +102.1% 4,880 $95K
Aster Capital Management (DIFC) Ltd 0.04% New 4,310 $84K
Cwm, LLC 0.00% Add +14.9% 4,028 $79K
Amalgamated Bank 0.00% Add +38.8% 3,889 $76K
KBC Group NV 0.00% No change 3,135 $61K
GF Fund Management Co. LTD. 0.00% Reduce -8.3% 2,806 $55K
Chung Wu Investment Group, LLC 0.04% Add +16.7% 2,800 $55K
STRS Ohio 0.00% New 2,600 $51K
Caption Management, LLC 0.00% New 2,500 $49K
Jones Financial Companies LLLP 0.00% No change 1,199 $23K
Versant Capital Management, Inc 0.00% No change 859 $17K
GAMMA Investing LLC 0.00% Add +29.6% 841 $16K
Tower Research Capital LLC (TRC) 0.00% Reduce -91.0% 730 $14K
Group One Trading LLC 0.00% Reduce -66.8% 650 $13K
Osaic Holdings, Inc. 0.00% Reduce -0.9% 635 $12K
Allworth Financial LP 0.00% Add +12.9% 559 $11K
Smartleaf Asset Management LLC 0.00% Add +568.7% 555 $11K
Essential Partners LLC 0.00% Add +1.4% 445 $9K
PNC Financial Services Group, Inc. 0.00% Reduce -9.1% 418 $8K
Daiwa Securities Group Inc. 0.00% Add +14.3% 424 $8K
US Bancorp \de 0.00% Add +10.8% 400 $8K
Optiver Holding B.V. 0.00% Reduce -56.3% 395 $8K
First Horizon Corp. 0.00% Reduce -2.0% 382 $7K
Signaturefd, LLC 0.00% Add +15.1% 320 $6K
Truvestments Capital LLC 0.00% No change 295 $6K
MassMutual Private Wealth & Trust, FSB 0.00% No change 243 $5K
Aspect Partners, LLC 0.00% Reduce -62.8% 225 $4K
Flagship Harbor Advisors, LLC 0.00% New 200 $4K
Fideuram - Intesa Sanpaolo Private Banking S.P.A. 0.00% — 200 $4K
National Bank of Canada 0.00% Add +33.3% 200 $4K
Rothschild Investment LLC 0.00% Add +3.0% 170 $3K
SBI Securities Co., Ltd. 0.00% Reduce -6.3% 150 $3K
Geneos Wealth Management Inc. 0.00% New 138 $3K
EverSource Wealth Advisors, LLC 0.00% No change 97 $2K
IFP Advisors, Inc 0.00% Reduce -1.0% 95 $2K
MRP Capital Investments, LLC 0.00% New 75 $1K
Parkside Financial Bank & Trust 0.00% Add +75.0% 70 $1K
Quadrant Capital Group LLC 0.00% No change 67 $1K
Basecamp Wealth Advisors LLC 0.00% — 42 $822
Cornerstone Financial Management LLC 0.00% — 40 $782
Parallel Advisors, LLC 0.00% No change 27 $528
Bell Investment Advisors, Inc 0.00% New 26 $509
Larson Financial Group LLC 0.00% Add +15.8% 22 $430
Arax Advisory Partners 0.00% Reduce -96.3% 18 $352
Farther Finance Advisors, LLC 0.00% Add +13.3% 17 $333
True Wealth Design, LLC 0.00% No change 13 $255
Dunhill Financial, LLC 0.00% New 1 $17

"% of holder's portfolio" is DYN's weight in each manager's 13F, not the share of Dyne Therapeutics Inc. the manager owns.