Engene HoldingsENGN
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 58 institutions reported holding Engene Holdings Inc. (ENGN) in their 13F filings, up 21 from Q3 2025. 25 opened new positions and 6 sold out. The largest holders were FCPM III Services B.V. ($87.0M), Perceptive Advisors LLC ($53.0M) and Venrock Adviser, LLC ($43.1M). 4 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Engene Holdings Inc.
- CUSIP
- 29286M105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 25 | $107.0M |
| Exits | 6 | $22.7M |
All 13F filers, Q3 2025 → Q4 2025: 25,432,213 shares bought and 7,801,167 shares sold, net +17,631,046 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 58 holders
| FCPM III Services B.V. | 11.40% | No change | 9,632,561 | $87.0M |
| Perceptive Advisors LLC | 0.97% | Add +179.8% | 5,869,076 | $53.0M |
| Venrock Adviser, LLC | 2.13% | Reduce -5.5% | 4,771,414 | $43.1M |
| Deep Track Capital, LP | 0.90% | Add +95.5% | 4,377,572 | $39.5M |
| Cormorant Asset Management, LP | 2.05% | Add +72.2% | 4,000,000 | $36.1M |
| Blue Owl Capital Holdings LP | 9.46% | Add +2.5% | 3,360,937 | $30.3M |
| Siren, L.L.C. | 0.90% | New | 3,336,264 | $30.1M |
| Braidwell LP | 1.08% | Add +38.2% | 3,131,319 | $28.3M |
| Nextech Invest Ltd. | 1.85% | New | 2,124,943 | $19.2M |
| Janus Henderson Group PLC | 0.01% | New | 1,900,000 | $17.1M |
| MPM Bioimpact LLC | 1.90% | Add +247.1% | 1,840,898 | $16.6M |
| Millennium Management | 0.01% | Add +7214.0% | 1,499,520 | $13.5M |
| Kynam Capital Management, LP | 0.88% | Reduce -70.1% | 1,492,898 | $13.5M |
| Franklin Resources Inc. | 0.00% | Add +33.7% | 1,388,000 | $12.5M |
| Polar Capital Holdings Plc | 0.05% | New | 1,142,982 | $10.3M |
| Vestal Point Capital, LP | 0.35% | Add +185.1% | 1,055,000 | $9.5M |
| Eventide Asset Management, LLC | 0.13% | New | 950,000 | $8.6M |
| Omega Fund Management, LLC | 2.76% | Add +66.5% | 876,357 | $7.9M |
| SR One Capital Management, LP | 0.96% | No change | 747,750 | $6.8M |
| Morgan Stanley | 0.00% | Add +65.1% | 718,485 | $6.5M |
| Affinity Asset Advisors, LLC | 0.43% | Add +735.5% | 643,370 | $5.8M |
| Point72 Asset Management | 0.01% | Reduce -53.5% | 561,797 | $5.1M |
| Eversept Partners, LP | 0.23% | New | 455,835 | $4.1M |
| Privium Fund Management B.V. | 0.59% | New | 352,087 | $3.2M |
| Marshall Wace, LLP | 0.00% | No change | 343,928 | $3.1M |
| ADAR1 Capital Management, LLC | 0.21% | New | 303,686 | $2.7M |
| Monashee Investment Management LLC | 1.57% | New | 295,000 | $2.7M |
| Woodline Partners LP | 0.01% | New | 250,000 | $2.3M |
| Elmind Capital, LP | 0.56% | — | 210,000 | $1.9M |
| DAFNA Capital Management LLC | 0.35% | New | 163,645 | $1.5M |
| Two Sigma Investments, LP | 0.00% | New | 161,512 | $1.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +0.2% | 147,889 | $1.3M |
| Deeter Investments LLP | 0.18% | — | 90,000 | $813K |
| Kennedy Capital Management LLC | 0.01% | New | 76,765 | $693K |
| HRT Financial LP | 0.00% | New | 64,380 | $581K |
| Jane Street Group, LLC | 0.00% | New | 56,454 | $510K |
| Quadrature Capital Ltd | 0.00% | New | 48,583 | $439K |
| BNP Paribas Financial Markets | 0.00% | New | 35,877 | $324K |
| Virtus Investment Advisers, LLC | 0.08% | New | 31,445 | $284K |
| Northern Trust Corp. | 0.00% | Reduce -0.7% | 30,085 | $272K |
| Geode Capital Management, LLC | 0.00% | No change | 29,018 | $262K |
| Citadel Advisors | 0.00% | Reduce -56.5% | 25,383 | $229K |
| Pale Fire Capital SE | 0.03% | Add +39.1% | 24,004 | $217K |
| American Century Companies Inc. | 0.00% | New | 23,980 | $217K |
| XTX Topco Ltd | 0.01% | New | 23,922 | $216K |
| Renaissance Technologies | 0.00% | New | 20,782 | $188K |
| Raymond James Financial Inc. | 0.00% | Add +99.6% | 19,960 | $180K |
| Two Sigma Advisers, LP | 0.00% | New | 17,300 | $156K |
| Schonfeld Strategic Advisors LLC | 0.00% | Reduce -33.6% | 16,645 | $150K |
| Jump Financial, LLC | 0.00% | New | 13,400 | $121K |
| Wells Fargo & Company | 0.00% | Reduce -37.4% | 11,217 | $101K |
| PFS Partners, LLC | 0.05% | Add +22.2% | 11,000 | $99K |
| Royal Bank of Canada | 0.00% | No change | 7,915 | $71K |
| JPMorgan Chase & Co. | 0.00% | New | 2,614 | $24K |
| Citigroup Inc. | 0.00% | Add +168700.0% | 1,688 | $15K |
| UBS Group AG | 0.00% | New | 1,597 | $14K |
| MAI Capital Management | 0.00% | No change | 776 | $7K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -9.7% | 28 | $253 |
"% of holder's portfolio" is ENGN's weight in each manager's 13F, not the share of Engene Holdings Inc. the manager owns.