Edgewise TherapeuticsEWTX
13F holders, Q2 2025 (June 30)178holders −14
29new positions
42sold out
4famous investors
$13.11avg. 13F price*
At the end of Q2 2025, 178 institutions reported holding Edgewise Therapeutics Inc. (EWTX) in their 13F filings, down 14 from Q1 2025. 29 opened new positions and 42 sold out. The largest holders were Orbimed Advisors LLC ($203.4M), Ra Capital Management, L.P. ($129.8M) and Baker Bros. Advisors LP ($95.8M). 4 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Edgewise Therapeutics Inc.
- CUSIP
- 28036F105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 29 | $32.1M |
| Exits | 42 | $105.8M |
All 13F filers, Q1 2025 → Q2 2025: 22,131,726 shares bought and 8,710,296 shares sold, net +13,421,430 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 178 holders
| Orbimed Advisors LLC | 5.12% | Add +3.3% | 15,518,492 | $203.4M |
| Ra Capital Management, L.P. | 2.19% | Add +11.2% | 9,902,633 | $129.8M |
| Baker Bros. Advisors LP | 0.93% | Add +18.7% | 7,305,940 | $95.8M |
| BlackRock, Inc. | 0.00% | Add +4.6% | 6,781,046 | $88.9M |
| Paradigm Biocapital Advisors LP | 3.44% | Add +39.8% | 6,142,344 | $80.5M |
| Janus Henderson Group PLC | 0.04% | Add +4.2% | 5,503,349 | $72.1M |
| Novo Holdings A/S | 4.95% | No change | 5,350,000 | $70.1M |
| Braidwell LP | 3.27% | Add +111.9% | 5,210,831 | $68.3M |
| Vanguard Group Inc. | 0.00% | Add +12.7% | 4,841,500 | $63.5M |
| Perceptive Advisors LLC | 2.28% | Reduce -29.1% | 4,639,949 | $60.8M |
| Cormorant Asset Management, LP | 4.15% | Add +3.7% | 4,251,992 | $55.7M |
| Siren, L.L.C. | 2.14% | Add +86.3% | 3,160,298 | $41.4M |
| Bellevue Group AG | 0.80% | Add +94.3% | 2,775,997 | $36.4M |
| Driehaus Capital Management LLC | 0.22% | Add +52.8% | 2,101,781 | $27.6M |
| Deerfield Management Company, L.P. | 0.55% | Reduce -0.5% | 2,067,320 | $27.1M |
| Geode Capital Management, LLC | 0.00% | Add +8.6% | 1,797,215 | $23.6M |
| State Street Corp. | 0.00% | Add +3.7% | 1,781,501 | $23.4M |
| MPM Bioimpact LLC | 3.91% | Add +55.7% | 1,720,741 | $22.6M |
| First Light Asset Management, LLC | 2.91% | Reduce -7.5% | 1,714,019 | $22.5M |
| Artisan Partners Limited Partnership | 0.03% | Add +50.4% | 1,379,068 | $18.1M |
| Woodline Partners LP | 0.08% | Add +0.0% | 1,096,863 | $14.4M |
| Dimensional Fund Advisors LP | 0.00% | Add +57.1% | 1,048,936 | $13.8M |
| New Leaf Venture Partners, L.L.C. | 25.51% | No change | 1,030,161 | $13.5M |
| Integral Health Asset Management, LLC | 1.22% | Add +48.1% | 1,000,000 | $13.1M |
| Polar Capital Holdings Plc | 0.07% | Add +290.0% | 975,000 | $12.8M |
| Millennium Management | 0.01% | Add +49.9% | 921,965 | $12.1M |
| American Century Companies Inc. | 0.01% | Add +0.4% | 783,166 | $10.3M |
| Morgan Stanley | 0.00% | Add +77.9% | 727,714 | $9.5M |
| Citigroup Inc. | 0.01% | Add +875.5% | 724,899 | $9.5M |
| Sofinnova Investments, Inc. | 0.64% | Add +109.5% | 716,873 | $9.4M |
| Parkman Healthcare Partners LLC | 0.98% | Add +52.2% | 647,331 | $8.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +72.3% | 631,743 | $8.3M |
| Northern Trust Corp. | 0.00% | Reduce -0.6% | 602,898 | $7.9M |
| D. E. Shaw & Co. | 0.01% | Add +323.6% | 595,432 | $7.8M |
| Foresite Capital Management VI LLC | 4.31% | No change | 585,000 | $7.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +11.1% | 579,104 | $7.6M |
| Eventide Asset Management, LLC | 0.13% | No change | 568,310 | $7.5M |
| Sio Capital Management, LLC | 2.84% | New | 539,730 | $7.1M |
| Qube Research & Technologies Ltd | 0.01% | Add +25.7% | 499,917 | $6.6M |
| Opaleye Management Inc. | 1.33% | Add +24.1% | 490,000 | $6.4M |
| FMR LLC | 0.00% | Add +153.0% | 470,717 | $6.2M |
| Aberdeen Group plc | 0.01% | Add +41.6% | 443,319 | $5.8M |
| Victory Capital Management Inc. | 0.00% | New | 442,837 | $5.8M |
| Tang Capital Management LLC | 0.29% | Add +43.8% | 431,300 | $5.7M |
| Granahan Investment Management, LLC | 0.22% | Add +86.3% | 405,478 | $5.3M |
| Eversept Partners, LP | 0.52% | New | 392,739 | $5.1M |
| Citadel Advisors | 0.00% | Add +234.3% | 325,249 | $4.3M |
| Nuveen, LLC | 0.00% | Add +56.6% | 317,173 | $4.2M |
| Federated Hermes, Inc. | 0.01% | Add +395525.0% | 316,500 | $4.1M |
| Voloridge Investment Management, LLC | 0.01% | New | 284,551 | $3.7M |
| Barclays PLC | 0.00% | Add +159.1% | 281,250 | $3.7M |
| Bank of America Corp. | 0.00% | Reduce -63.4% | 254,429 | $3.3M |
| Kynam Capital Management, LP | 0.36% | New | 253,979 | $3.3M |
| Kennedy Capital Management LLC | 0.08% | Add +12.4% | 252,524 | $3.3M |
| DAFNA Capital Management LLC | 0.87% | Add +30.0% | 238,140 | $3.1M |
| Candriam S.C.A. | 0.02% | Reduce -0.8% | 223,990 | $2.9M |
| Bank of New York Mellon Corp | 0.00% | Add +1.0% | 212,858 | $2.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -29.8% | 191,606 | $2.5M |
| UBS Group AG | 0.00% | Reduce -29.9% | 170,982 | $2.2M |
| Schonfeld Strategic Advisors LLC | 0.02% | Reduce -40.0% | 167,340 | $2.2M |
| Neuberger Berman Group LLC | 0.00% | Add +62.0% | 165,535 | $2.2M |
| Schroder Investment Management Group | 0.00% | Add +90.8% | 151,062 | $2.0M |
| Deutsche Bank AG | 0.00% | Reduce -60.8% | 147,525 | $1.9M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +47.8% | 132,178 | $1.7M |
| Exome Asset Management LLC | 1.35% | Add +74.2% | 124,470 | $1.6M |
| Jump Financial, LLC | 0.02% | New | 121,705 | $1.6M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 80,000 | $1.6M |
| Susquehanna International Group, LLP | 0.00% | Reduce -34.8% | 115,270 | $1.5M |
| Campbell & CO Investment Adviser LLC | 0.09% | New | 114,181 | $1.5M |
| Wellington Management Group LLP | 0.00% | Reduce -0.7% | 112,570 | $1.5M |
| Rhumbline Advisers | 0.00% | Add +3.4% | 112,483 | $1.5M |
| Quantum Private Wealth, LLC | 0.43% | Add +11.1% | 100,774 | $1.3M |
| Moody Aldrich Partners LLC | 0.25% | Reduce -45.2% | 99,848 | $1.3M |
| New York State Common Retirement Fund | 0.00% | Add +31.3% | 93,808 | $1.2M |
| Swiss National Bank | 0.00% | Add +9.0% | 90,000 | $1.2M |
| Walleye Capital LLC | 0.01% | Add +437.0% | 86,882 | $1.1M |
| Twinbeech Capital LP | 0.02% | Reduce -22.4% | 78,280 | $1.0M |
| JPMorgan Chase & Co. | 0.00% | Reduce -15.1% | 77,616 | $1.0M |
| Alliancebernstein L.P. | 0.00% | No change | 77,260 | $1.0M |
| Soleus Capital Management, L.P. | 0.07% | Add +5.8% | 76,493 | $1.0M |
| HighVista Strategies LLC | 0.34% | Reduce -23.6% | 69,723 | $914K |
| XTX Topco Ltd | 0.03% | New | 60,739 | $796K |
| Alps Advisors Inc. | 0.00% | Reduce -16.4% | 56,798 | $745K |
| Invesco Ltd. | 0.00% | Add +16.7% | 56,158 | $736K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.02% | Add +38.2% | 55,292 | $725K |
| State of Wisconsin Investment Board | 0.00% | Reduce -24.1% | 54,019 | $708K |
| Legal & General Group Plc | 0.00% | Add +3.9% | 52,307 | $686K |
| HighMark Wealth Management LLC | 0.33% | Add +31454.5% | 52,065 | $683K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -82.8% | 50,682 | $665K |
| Jane Street Group, LLC | 0.00% | Add +240.1% | 50,185 | $658K |
| Norges Bank | 0.00% | No change | 47,755 | $626K |
| Franklin Resources Inc. | 0.00% | Reduce -1.0% | 45,806 | $601K |
| ExodusPoint Capital Management, LP | 0.01% | New | 45,255 | $593K |
| Verition Fund Management LLC | 0.00% | Add +26.9% | 44,069 | $578K |
| Intech Investment Management LLC | 0.01% | Reduce -4.6% | 44,065 | $578K |
| MetLife Investment Management, LLC | 0.00% | No change | 43,883 | $575K |
| Sei Investments Co. | 0.00% | Add +1.6% | 43,638 | $572K |
| Tudor Investment Corporation | 0.00% | Reduce -11.0% | 41,663 | $546K |
| Quantbot Technologies LP | 0.01% | New | 41,463 | $544K |
| Graham Capital Management, L.P. | 0.02% | Add +136.8% | 40,364 | $529K |
| ADAR1 Capital Management, LLC | 0.09% | Add +100.0% | 40,000 | $524K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -8.7% | 39,978 | $524K |
| Prelude Capital Management, LLC | 0.05% | Reduce -22.4% | 38,809 | $509K |
| Wells Fargo & Company | 0.00% | Add +9.2% | 38,384 | $503K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -32.7% | 38,328 | $502K |
| Skandinaviska Enskilda Banken AB (publ) | 0.00% | No change | 37,591 | $493K |
| California State Teachers Retirement System | 0.00% | Add +2.4% | 36,878 | $483K |
| Engineers Gate Manager LP | 0.01% | Reduce -4.0% | 34,909 | $458K |
| Algert Global LLC | 0.01% | New | 34,723 | $455K |
| Handelsbanken Fonder AB | 0.00% | Add +31.6% | 28,700 | $376K |
| Gsa Capital Partners LLP | 0.03% | New | 27,276 | $358K |
| Aquatic Capital Management LLC | 0.01% | New | 27,042 | $355K |
| Numerai GP LLC | 0.04% | New | 22,353 | $293K |
| AlphaQuest LLC | 0.03% | Add +128.6% | 21,390 | $280K |
| SummitTX Capital, L.P. | 0.01% | Add +121.2% | 21,380 | $280K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +11.2% | 21,120 | $277K |
| Voya Investment Management LLC | 0.00% | Reduce -92.9% | 19,913 | $261K |
| ProShare Advisors LLC | 0.00% | Reduce -6.5% | 18,888 | $248K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +12.3% | 17,356 | $228K |
| Creative Planning | 0.00% | Add +29.4% | 16,910 | $222K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 16,870 | $221K |
| Profund Advisors LLC | 0.01% | Reduce -3.8% | 15,085 | $198K |
| Arizona State Retirement System | 0.00% | Add +12.7% | 13,745 | $180K |
| Brevan Howard Capital Management LP | 0.00% | New | 13,561 | $178K |
| Nebula Research & Development LLC | 0.01% | New | 13,219 | $173K |
| Teacher Retirement System of Texas | 0.00% | Add +10.7% | 12,646 | $166K |
| Glenmede Investment Management, LP | 0.00% | — | 12,542 | $164K |
| HSBC Holdings PLC | 0.00% | Add +8.5% | 10,712 | $142K |
| KLP Kapitalforvaltning As | 0.00% | Add +55.9% | 10,600 | $139K |
| Sfmg, LLC | 0.01% | No change | 10,000 | $131K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +14.9% | 9,148 | $120K |
| BNP Paribas Financial Markets | 0.00% | Add +48.9% | 8,193 | $107K |
| Royal Bank of Canada | 0.00% | Add +34.3% | 7,694 | $100K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 7,594 | $100K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 7,073 | $93K |
| STRS Ohio | 0.00% | Add +60.5% | 6,100 | $80K |
| Virtus Investment Advisers, LLC | 0.03% | Add +4.6% | 6,098 | $80K |
| Simplex Trading, LLC | 0.00% | New | 4,183 | $54K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +28.2% | 4,062 | $53K |
| Canada Pension Plan Investment Board | 0.00% | New | 3,400 | $45K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 2,849 | $37K |
| Amalgamated Bank | 0.00% | No change | 2,521 | $33K |
| GF Fund Management Co. LTD. | 0.00% | No change | 2,424 | $32K |
| US Bancorp \de | 0.00% | Reduce -37.5% | 2,009 | $26K |
| Raymond James Financial Inc. | 0.00% | New | 1,558 | $20K |
| Winthrop Capital Management, LLC | 0.00% | New | 1,377 | $18K |
| Brooklyn Investment Group | 0.00% | New | 1,314 | $17K |
| GAMMA Investing LLC | 0.00% | Reduce -17.1% | 1,166 | $15K |
| Osaic Holdings, Inc. | 0.00% | Add +824.0% | 1,118 | $15K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -10.6% | 944 | $12K |
| Crowley Wealth Management, Inc. | 0.01% | No change | 560 | $7K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | New | 454 | $6K |
| Daiwa Securities Group Inc. | 0.00% | No change | 344 | $5K |
| Farther Finance Advisors, LLC | 0.00% | Add +4575.0% | 374 | $5K |
| Signaturefd, LLC | 0.00% | Reduce -26.2% | 363 | $5K |
| Quarry LP | 0.00% | Reduce -74.1% | 311 | $4K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Reduce -34.5% | 233 | $3K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -14.8% | 207 | $3K |
| Sterling Capital Management LLC | 0.00% | Add +128.0% | 171 | $2K |
| Fortitude Family Office, LLC | 0.00% | No change | 160 | $2K |
| Rothschild Investment LLC | 0.00% | Add +33.3% | 160 | $2K |
| Bessemer Group Inc. | 0.00% | New | 185 | $2K |
| Bfsg, LLC | 0.00% | No change | 100 | $1K |
| Versant Capital Management, Inc | 0.00% | Add +137.5% | 95 | $1K |
| Parallel Advisors, LLC | 0.00% | Reduce -28.6% | 95 | $1K |
| Cwm, LLC | 0.00% | Add +78.7% | 109 | $1K |
| EverSource Wealth Advisors, LLC | 0.00% | New | 61 | $800 |
| Riggs Asset Managment Co. Inc. | 0.00% | New | 49 | $643 |
| PNC Financial Services Group, Inc. | 0.00% | New | 49 | $642 |
| Arax Advisory Partners | 0.00% | New | 48 | $630 |
| National Bank of Canada | 0.00% | New | 40 | $524 |
| Comerica Bank | 0.00% | Reduce -71.1% | 35 | $470 |
| Parkside Financial Bank & Trust | 0.00% | Reduce -12.5% | 35 | $459 |
| Principal Securities, Inc. | 0.00% | No change | 27 | $354 |
| Smartleaf Asset Management LLC | 0.00% | Add +23.8% | 26 | $342 |
| Russell Investments Group, Ltd. | 0.00% | Add +26.3% | 24 | $315 |
| American National Bank & Trust | 0.00% | New | 2 | $26 |
| Covestor Ltd | 0.00% | Add +60.0% | 8 | $0 |
"% of holder's portfolio" is EWTX's weight in each manager's 13F, not the share of Edgewise Therapeutics Inc. the manager owns.