Edgewise TherapeuticsEWTX
13F holders, Q1 2026 (March 31)214holders +15
36new positions
23sold out
5famous investors
$31.40avg. 13F price*
At the end of Q1 2026, 214 institutions reported holding Edgewise Therapeutics Inc. (EWTX) in their 13F filings, up 15 from Q4 2025. 36 opened new positions and 23 sold out. The largest holders were Orbimed Advisors LLC ($488.8M), Ra Capital Management, L.P. ($328.5M) and Paradigm Biocapital Advisors LP ($232.0M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Edgewise Therapeutics Inc.
- CUSIP
- 28036F105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 36 | $28.7M |
| Exits | 23 | $41.2M |
All 13F filers, Q4 2025 → Q1 2026: 6,795,072 shares bought and 9,588,930 shares sold, net −2,793,858 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 214 holders
| Orbimed Advisors LLC | 11.06% | No change | 15,518,492 | $488.8M |
| Ra Capital Management, L.P. | 3.48% | No change | 10,428,437 | $328.5M |
| Paradigm Biocapital Advisors LP | 4.74% | Add +12.6% | 7,365,038 | $232.0M |
| Baker Bros. Advisors LP | 1.19% | No change | 6,575,940 | $207.1M |
| BlackRock, Inc. | 0.00% | Reduce -2.4% | 6,472,991 | $203.9M |
| Janus Henderson Group PLC | 0.09% | Add +29.5% | 5,915,556 | $186.3M |
| Novo Holdings A/S | 13.65% | No change | 5,350,000 | $168.5M |
| Driehaus Capital Management LLC | 1.04% | Add +6.8% | 4,477,942 | $141.1M |
| Siren, L.L.C. | 3.87% | Reduce -2.2% | 4,430,263 | $139.6M |
| Perceptive Advisors LLC | 2.76% | Reduce -0.8% | 4,423,974 | $139.4M |
| Vanguard Capital Management LLC | 0.00% | — | 3,788,161 | $119.3M |
| Cormorant Asset Management, LP | 5.18% | Reduce -0.8% | 3,260,000 | $102.7M |
| Braidwell LP | 2.82% | Reduce -55.0% | 2,347,583 | $73.9M |
| Morgan Stanley | 0.00% | Reduce -22.8% | 2,246,028 | $70.7M |
| Geode Capital Management, LLC | 0.00% | Add +2.5% | 1,789,819 | $56.4M |
| State Street Corp. | 0.00% | Reduce -0.0% | 1,716,823 | $54.1M |
| MPM Bioimpact LLC | 4.04% | Add +0.3% | 1,660,696 | $52.3M |
| Integral Health Asset Management, LLC | 2.67% | Add +6.7% | 1,600,000 | $50.4M |
| Bellevue Group AG | 1.15% | No change | 1,528,518 | $48.1M |
| Soleus Capital Management, L.P. | 1.85% | Add +59.3% | 1,449,915 | $45.7M |
| Alliancebernstein L.P. | 0.01% | Add +66.2% | 1,722,169 | $42.7M |
| Bank of America Corp. | 0.00% | Reduce -10.0% | 1,327,360 | $41.8M |
| UBS Group AG | 0.01% | Reduce -38.1% | 1,311,125 | $41.3M |
| Dimensional Fund Advisors LP | 0.01% | Add +0.5% | 1,219,717 | $38.4M |
| American Century Companies Inc. | 0.02% | Reduce -3.3% | 1,147,176 | $36.1M |
| FMR LLC | 0.00% | Add +46.8% | 1,017,052 | $32.0M |
| First Light Asset Management, LLC | 2.83% | Reduce -36.3% | 1,001,846 | $31.6M |
| Aberdeen Group plc | 0.04% | Add +0.5% | 826,059 | $26.0M |
| Qube Research & Technologies Ltd | 0.04% | Add +178.8% | 825,910 | $26.0M |
| Victory Capital Management Inc. | 0.02% | Add +5.7% | 789,043 | $24.9M |
| Artisan Partners Limited Partnership | 0.03% | Reduce -6.4% | 659,067 | $20.8M |
| Marshall Wace, LLP | 0.02% | Reduce -4.9% | 648,393 | $20.4M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -12.3% | 629,820 | $19.8M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -2.5% | 596,310 | $18.8M |
| Northern Trust Corp. | 0.00% | Add +3.0% | 576,556 | $18.2M |
| Vanguard Portfolio Management LLC | 0.00% | — | 557,260 | $17.6M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 521,726 | $16.4M |
| Opaleye Management Inc. | 2.07% | No change | 500,000 | $15.8M |
| Candriam S.C.A. | 0.07% | Reduce -10.7% | 447,416 | $14.1M |
| Citadel Advisors | 0.01% | Add +248.5% | 429,032 | $13.5M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.02% | Reduce -36.9% | 404,200 | $12.7M |
| Sofinnova Investments, Inc. | 0.61% | Reduce -11.7% | 386,498 | $12.2M |
| Squadron Capital Management LLC | 4.41% | No change | 350,000 | $11.0M |
| Millennium Management | 0.01% | Add +171.2% | 342,867 | $10.8M |
| Nuveen, LLC | 0.00% | Add +98.1% | 335,783 | $10.6M |
| Parkman Healthcare Partners LLC | 1.05% | Reduce -24.5% | 322,828 | $10.2M |
| Stempoint Capital LP | 1.76% | Reduce -19.4% | 290,864 | $9.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | Add +4.4% | 283,312 | $8.9M |
| Sio Capital Management, LLC | 1.22% | Add +13.3% | 268,986 | $8.5M |
| Kennedy Capital Management LLC | 0.18% | Add +9.4% | 264,204 | $8.3M |
| Woodline Partners LP | 0.03% | Add +0.0% | 224,290 | $7.1M |
| Deutsche Bank AG | 0.00% | Add +3.3% | 221,868 | $7.0M |
| Peregrine Capital Management LLC | 0.24% | New | 208,672 | $6.6M |
| SEB Asset Management AB | 0.03% | — | 206,512 | $6.5M |
| Granahan Investment Management, LLC | 0.31% | Reduce -13.5% | 200,843 | $6.3M |
| Ameriprise Financial Inc. | 0.00% | Reduce -0.8% | 200,661 | $6.3M |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.1% | 192,434 | $6.1M |
| Barclays PLC | 0.00% | Reduce -52.5% | 177,244 | $5.6M |
| Neuberger Berman Group LLC | 0.00% | Add +32.7% | 168,678 | $5.3M |
| Ally Bridge Group (NY) LLC | 5.04% | Reduce -17.4% | 161,000 | $5.1M |
| Eventide Asset Management, LLC | 0.08% | Reduce -73.6% | 149,863 | $4.7M |
| Freestone Grove Partners LP | 0.03% | New | 148,426 | $4.7M |
| JPMorgan Chase & Co. | 0.00% | Add +1.1% | 147,573 | $4.5M |
| Schroder Investment Management Group | 0.00% | No change | 145,286 | $4.4M |
| Invesco Ltd. | 0.00% | Add +83.5% | 138,399 | $4.4M |
| KVP Capital Advisors, LP | 3.13% | No change | 133,000 | $4.2M |
| Quantum Private Wealth, LLC | 1.13% | Add +10.0% | 116,624 | $3.7M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +17.0% | 114,720 | $3.6M |
| Moody Aldrich Partners LLC | 0.65% | Add +164.6% | 114,141 | $3.6M |
| DAFNA Capital Management LLC | 0.82% | Reduce -29.7% | 112,236 | $3.5M |
| D. E. Shaw & Co. | 0.00% | Reduce -73.4% | 104,863 | $3.3M |
| Swiss National Bank | 0.00% | No change | 103,900 | $3.3M |
| Schonfeld Strategic Advisors LLC | 0.03% | Add +67.0% | 99,075 | $3.1M |
| HighVista Strategies LLC | 0.80% | Reduce -46.3% | 91,931 | $2.9M |
| ADAR1 Capital Management, LLC | 0.17% | Reduce -0.4% | 90,599 | $2.9M |
| New York State Common Retirement Fund | 0.00% | No change | 88,937 | $2.8M |
| Alps Advisors Inc. | 0.01% | Add +0.5% | 87,326 | $2.8M |
| Rhumbline Advisers | 0.00% | Reduce -1.8% | 83,540 | $2.6M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 80,000 | $2.6M |
| California State Teachers Retirement System | 0.00% | Add +45.7% | 73,419 | $2.3M |
| T. Rowe Price Associates Inc. | 0.00% | Add +21.1% | 69,427 | $2.2M |
| Nomura Asset Management International Inc. | 0.00% | New | 67,408 | $2.1M |
| Artia Global Partners LP | 0.47% | New | 65,500 | $2.1M |
| J. Goldman & Co LP | 0.09% | New | 61,421 | $1.9M |
| Federated Hermes, Inc. | 0.00% | Reduce -30.8% | 56,778 | $1.8M |
| HighMark Wealth Management LLC | 0.68% | No change | 53,179 | $1.7M |
| Two Sigma Investments, LP | 0.00% | No change | 50,848 | $1.6M |
| Ishara Investments LP | 1.57% | Reduce -15.2% | 49,200 | $1.5M |
| Sei Investments Co. | 0.00% | Add +57.1% | 49,082 | $1.5M |
| Jain Global LLC | 0.02% | Reduce -59.3% | 46,401 | $1.5M |
| Silverarc Capital Management, LLC | 0.16% | Add +1.3% | 42,615 | $1.3M |
| Legal & General Group Plc | 0.00% | Reduce -19.4% | 42,537 | $1.3M |
| Franklin Resources Inc. | 0.00% | Reduce -3.3% | 41,726 | $1.3M |
| Voya Investment Management LLC | 0.00% | Reduce -1.3% | 39,153 | $1.2M |
| Caption Management, LLC | 0.06% | New | 38,675 | $1.2M |
| Knights of Columbus Asset Advisors LLC | 0.07% | Reduce -0.7% | 38,414 | $1.2M |
| MetLife Investment Management, LLC | 0.01% | Reduce -0.5% | 38,084 | $1.2M |
| Longaeva Partners L.P. | 0.06% | New | 36,931 | $1.2M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 35,744 | $1.1M |
| Jane Street Group, LLC | 0.00% | New | 35,578 | $1.1M |
"% of holder's portfolio" is EWTX's weight in each manager's 13F, not the share of Edgewise Therapeutics Inc. the manager owns.