Edgewise TherapeuticsEWTX
13F holders, Q3 2025 (September 30)173holders −5
17new positions
21sold out
3famous investors
$16.22avg. 13F price*
At the end of Q3 2025, 173 institutions reported holding Edgewise Therapeutics Inc. (EWTX) in their 13F filings, down 5 from Q2 2025. 17 opened new positions and 21 sold out. The largest holders were Orbimed Advisors LLC ($251.7M), Ra Capital Management, L.P. ($169.1M) and Baker Bros. Advisors LP ($118.5M). 3 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Edgewise Therapeutics Inc.
- CUSIP
- 28036F105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 17 | $5.0M |
| Exits | 21 | $32.6M |
All 13F filers, Q2 2025 → Q3 2025: 3,868,449 shares bought and 10,581,377 shares sold, net −6,712,928 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 173 holders
| Orbimed Advisors LLC | 6.04% | No change | 15,518,492 | $251.7M |
| Ra Capital Management, L.P. | 2.09% | Add +5.3% | 10,428,437 | $169.1M |
| Baker Bros. Advisors LP | 0.86% | No change | 7,305,940 | $118.5M |
| BlackRock, Inc. | 0.00% | Reduce -6.3% | 6,351,487 | $103.0M |
| Paradigm Biocapital Advisors LP | 2.96% | Add +0.5% | 6,170,131 | $100.1M |
| Novo Holdings A/S | 5.59% | No change | 5,350,000 | $86.8M |
| Braidwell LP | 3.42% | No change | 5,210,831 | $84.5M |
| Janus Henderson Group PLC | 0.04% | Reduce -9.5% | 4,979,331 | $80.8M |
| Vanguard Group Inc. | 0.00% | Reduce -0.8% | 4,803,941 | $77.9M |
| Cormorant Asset Management, LP | 4.49% | Reduce -5.7% | 4,010,000 | $65.0M |
| Siren, L.L.C. | 2.47% | Add +23.3% | 3,897,099 | $63.2M |
| Perceptive Advisors LLC | 1.81% | Reduce -18.2% | 3,795,894 | $61.6M |
| Bellevue Group AG | 0.94% | No change | 2,775,997 | $45.0M |
| Driehaus Capital Management LLC | 0.26% | Add +6.0% | 2,228,285 | $36.1M |
| MPM Bioimpact LLC | 4.57% | No change | 1,720,741 | $27.9M |
| Geode Capital Management, LLC | 0.00% | Reduce -4.4% | 1,717,641 | $27.9M |
| State Street Corp. | 0.00% | Reduce -4.6% | 1,699,909 | $27.6M |
| Integral Health Asset Management, LLC | 1.77% | Add +50.0% | 1,500,000 | $24.3M |
| First Light Asset Management, LLC | 2.16% | Reduce -17.4% | 1,414,994 | $23.0M |
| Dimensional Fund Advisors LP | 0.00% | Add +12.8% | 1,183,136 | $19.2M |
| American Century Companies Inc. | 0.01% | Add +39.9% | 1,095,473 | $17.8M |
| New Leaf Venture Partners, L.L.C. | 38.82% | No change | 1,030,161 | $16.7M |
| Morgan Stanley | 0.00% | Add +19.5% | 869,678 | $14.1M |
| Deerfield Management Company, L.P. | 0.21% | Reduce -63.0% | 765,694 | $12.4M |
| Millennium Management | 0.01% | Reduce -21.3% | 725,425 | $11.8M |
| Artisan Partners Limited Partnership | 0.02% | Reduce -47.9% | 718,175 | $11.6M |
| D. E. Shaw & Co. | 0.01% | Add +13.8% | 677,561 | $11.0M |
| Aberdeen Group plc | 0.02% | Add +39.8% | 619,878 | $10.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +3.2% | 597,603 | $9.7M |
| Northern Trust Corp. | 0.00% | Reduce -2.5% | 587,882 | $9.5M |
| Eventide Asset Management, LLC | 0.15% | No change | 568,310 | $9.2M |
| Qube Research & Technologies Ltd | 0.01% | Add +11.2% | 555,713 | $9.0M |
| Parkman Healthcare Partners LLC | 0.98% | Reduce -15.0% | 550,173 | $8.9M |
| Citigroup Inc. | 0.01% | Reduce -25.7% | 538,453 | $8.7M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -16.4% | 527,827 | $8.6M |
| Sofinnova Investments, Inc. | 0.52% | Reduce -27.4% | 520,240 | $8.4M |
| Eversept Partners, LP | 0.62% | Add +27.9% | 502,234 | $8.1M |
| Opaleye Management Inc. | 1.15% | Add +2.0% | 500,000 | $8.1M |
| Victory Capital Management Inc. | 0.00% | Add +12.6% | 498,646 | $8.1M |
| Tang Capital Management LLC | 0.27% | No change | 431,300 | $7.0M |
| Granahan Investment Management, LLC | 0.23% | Reduce -16.2% | 339,617 | $5.5M |
| Bank of America Corp. | 0.00% | Add +26.2% | 321,132 | $5.2M |
| Sio Capital Management, LLC | 1.26% | Reduce -43.1% | 307,181 | $5.0M |
| Kynam Capital Management, LP | 0.31% | No change | 253,979 | $4.1M |
| FMR LLC | 0.00% | Reduce -46.2% | 253,325 | $4.1M |
| Kennedy Capital Management LLC | 0.09% | Reduce -0.8% | 250,622 | $4.1M |
| Barclays PLC | 0.00% | Reduce -16.6% | 234,650 | $3.8M |
| Woodline Partners LP | 0.02% | Reduce -79.6% | 224,190 | $3.6M |
| Candriam S.C.A. | 0.02% | Reduce -1.3% | 221,159 | $3.6M |
| Neuberger Berman Group LLC | 0.00% | Add +32.7% | 219,646 | $3.6M |
| DAFNA Capital Management LLC | 0.87% | Reduce -10.3% | 213,736 | $3.5M |
| HighVista Strategies LLC | 0.83% | Add +198.5% | 208,101 | $3.4M |
| Bank of New York Mellon Corp | 0.00% | Reduce -4.0% | 204,242 | $3.3M |
| Exome Asset Management LLC | 1.86% | Add +39.3% | 173,439 | $2.8M |
| Nuveen, LLC | 0.00% | Reduce -45.5% | 172,707 | $2.8M |
| Deutsche Bank AG | 0.00% | Add +5.0% | 154,896 | $2.5M |
| Schroder Investment Management Group | 0.00% | No change | 151,062 | $2.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -27.4% | 139,112 | $2.3M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +0.3% | 132,503 | $2.1M |
| Wellington Management Group LLP | 0.00% | Add +1.7% | 114,531 | $1.9M |
| UBS Group AG | 0.00% | Reduce -33.3% | 114,128 | $1.9M |
| Gsa Capital Partners LLP | 0.15% | Add +315.2% | 113,243 | $1.8M |
| Quantum Private Wealth, LLC | 0.50% | Add +5.1% | 105,874 | $1.7M |
| Rhumbline Advisers | 0.00% | Reduce -6.8% | 104,829 | $1.7M |
| Swiss National Bank | 0.00% | Add +13.2% | 101,900 | $1.7M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 80,000 | $1.5M |
| New York State Common Retirement Fund | 0.00% | Reduce -11.1% | 83,437 | $1.4M |
| Moody Aldrich Partners LLC | 0.26% | Reduce -16.9% | 82,941 | $1.3M |
| Jump Financial, LLC | 0.02% | Reduce -33.6% | 80,825 | $1.3M |
| Alliancebernstein L.P. | 0.00% | No change | 77,260 | $1.3M |
| Squarepoint Ops LLC | 0.00% | New | 75,276 | $1.2M |
| Jane Street Group, LLC | 0.00% | Add +39.5% | 69,998 | $1.1M |
| JPMorgan Chase & Co. | 0.00% | Reduce -11.5% | 68,720 | $1.1M |
| Invesco Ltd. | 0.00% | Add +17.6% | 66,056 | $1.1M |
| Federated Hermes, Inc. | 0.00% | Reduce -81.3% | 59,256 | $961K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | New | 57,300 | $929K |
| Legal & General Group Plc | 0.00% | Add +7.0% | 55,941 | $907K |
| HighMark Wealth Management LLC | 0.38% | Add +2.1% | 53,179 | $863K |
| HRT Financial LP | 0.00% | New | 52,203 | $846K |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -68.9% | 51,989 | $843K |
| T. Rowe Price Associates Inc. | 0.00% | Add +1.4% | 51,386 | $834K |
| Alps Advisors Inc. | 0.00% | Reduce -10.0% | 51,112 | $829K |
| California State Teachers Retirement System | 0.00% | Add +37.7% | 50,793 | $824K |
| Prelude Capital Management, LLC | 0.06% | Add +26.8% | 49,205 | $798K |
| Franklin Resources Inc. | 0.00% | Add +5.3% | 48,220 | $782K |
| Susquehanna International Group, LLP | 0.00% | Reduce -60.4% | 45,635 | $740K |
| MetLife Investment Management, LLC | 0.00% | No change | 43,883 | $712K |
| Wells Fargo & Company | 0.00% | Add +9.9% | 42,196 | $684K |
| Algert Global LLC | 0.01% | Add +18.0% | 40,963 | $664K |
| ADAR1 Capital Management, LLC | 0.06% | No change | 40,000 | $649K |
| Sei Investments Co. | 0.00% | Reduce -10.4% | 39,095 | $634K |
| Handelsbanken Fonder AB | 0.00% | Add +33.8% | 38,400 | $623K |
| State of Wisconsin Investment Board | 0.00% | Reduce -32.2% | 36,619 | $594K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -7.3% | 35,538 | $576K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -21.6% | 31,350 | $508K |
| Intech Investment Management LLC | 0.00% | Reduce -33.8% | 29,179 | $473K |
| Optimize Financial Inc. | 0.23% | New | 27,283 | $443K |
| Two Sigma Investments, LP | 0.00% | New | 26,266 | $426K |
| Trexquant Investment LP | 0.00% | New | 22,625 | $367K |
| Citadel Advisors | 0.00% | Reduce -93.1% | 22,317 | $362K |
| SummitTX Capital, L.P. | 0.01% | Reduce -2.8% | 20,782 | $337K |
| Fox Run Management, L.L.C. | 0.05% | New | 20,471 | $332K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +8.7% | 18,865 | $306K |
| Graham Capital Management, L.P. | 0.02% | Reduce -53.5% | 18,789 | $305K |
| China Universal Asset Management Co., Ltd. | 0.02% | Reduce -12.6% | 18,466 | $300K |
| Creative Planning | 0.00% | Add +6.7% | 18,036 | $293K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 16,870 | $274K |
| Royal Bank of Canada | 0.00% | Add +104.0% | 15,695 | $254K |
| Arizona State Retirement System | 0.00% | Add +13.1% | 15,549 | $252K |
| ProShare Advisors LLC | 0.00% | Reduce -19.0% | 15,291 | $248K |
| ExodusPoint Capital Management, LP | 0.00% | Reduce -67.6% | 14,672 | $238K |
| BNP Paribas Financial Markets | 0.00% | Add +74.5% | 14,297 | $232K |
| AlphaQuest LLC | 0.02% | Reduce -33.3% | 14,274 | $232K |
| Raymond James Financial Inc. | 0.00% | Add +758.7% | 13,379 | $217K |
| Teacher Retirement System of Texas | 0.00% | Add +1.3% | 12,815 | $208K |
| Voya Investment Management LLC | 0.00% | Reduce -37.6% | 12,417 | $201K |
| Profund Advisors LLC | 0.01% | Reduce -21.7% | 11,809 | $192K |
| Campbell & CO Investment Adviser LLC | 0.01% | Reduce -90.2% | 11,140 | $181K |
| Glenmede Investment Management, LP | 0.00% | Reduce -11.2% | 11,137 | $181K |
| Envestnet Asset Management Inc. | 0.00% | New | 10,837 | $176K |
| KLP Kapitalforvaltning As | 0.00% | No change | 10,600 | $172K |
| Sfmg, LLC | 0.01% | No change | 10,000 | $162K |
| SG Americas Securities, LLC | 0.00% | New | 9,881 | $160K |
| Simplex Trading, LLC | 0.00% | Add +81.5% | 7,590 | $123K |
| Virtus Investment Advisers, LLC | 0.03% | Add +21.0% | 7,380 | $120K |
| Russell Investments Group, Ltd. | 0.00% | Add +29858.3% | 7,190 | $117K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -3.0% | 6,863 | $111K |
| Ameritas Investment Partners, Inc. | 0.00% | Reduce -25.8% | 5,638 | $91K |
| Canada Pension Plan Investment Board | 0.00% | Add +32.4% | 4,500 | $73K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.3% | 4,073 | $66K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 2,849 | $46K |
| Amalgamated Bank | 0.00% | No change | 2,521 | $41K |
| Bessemer Group Inc. | 0.00% | Add +1170.3% | 2,350 | $38K |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 2,304 | $37K |
| US Bancorp \de | 0.00% | Add +14.1% | 2,292 | $37K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -6.5% | 2,266 | $37K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -82.1% | 1,639 | $27K |
| Winthrop Capital Management, LLC | 0.01% | No change | 1,377 | $22K |
| GAMMA Investing LLC | 0.00% | Reduce -0.7% | 1,158 | $19K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -7.4% | 874 | $14K |
| Kayne Anderson Rudnick Investment Management LLC | 0.00% | New | 622 | $10K |
| Crowley Wealth Management, Inc. | 0.01% | No change | 560 | $9K |
| Farther Finance Advisors, LLC | 0.00% | Add +49.2% | 558 | $9K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +14.8% | 521 | $8K |
| Optiver Holding B.V. | 0.00% | New | 468 | $8K |
| Osaic Holdings, Inc. | 0.00% | Reduce -60.0% | 447 | $7K |
| Daiwa Securities Group Inc. | 0.00% | No change | 344 | $6K |
| Signaturefd, LLC | 0.00% | No change | 363 | $6K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +47.6% | 344 | $6K |
| SBI Securities Co., Ltd. | 0.00% | No change | 207 | $3K |
| Sterling Capital Management LLC | 0.00% | Reduce -4.7% | 163 | $3K |
| Fortitude Family Office, LLC | 0.00% | No change | 160 | $3K |
| Advisory Services Network, LLC | 0.00% | New | 151 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +132.8% | 142 | $2K |
| Rothschild Investment LLC | 0.00% | Reduce -15.6% | 135 | $2K |
| Larson Financial Group LLC | 0.00% | New | 135 | $2K |
| Cwm, LLC | 0.00% | Add +21.1% | 132 | $2K |
| Arax Advisory Partners | 0.00% | Add +120.8% | 106 | $2K |
| Bfsg, LLC | 0.00% | No change | 100 | $2K |
| Versant Capital Management, Inc | 0.00% | No change | 95 | $2K |
| Parallel Advisors, LLC | 0.00% | No change | 95 | $2K |
| PNC Financial Services Group, Inc. | 0.00% | Add +36.7% | 67 | $1K |
| National Bank of Canada | 0.00% | No change | 40 | $649 |
| Comerica Bank | 0.00% | No change | 35 | $581 |
| Parkside Financial Bank & Trust | 0.00% | No change | 35 | $569 |
| Allworth Financial LP | 0.00% | New | 33 | $536 |
| Principal Securities, Inc. | 0.00% | No change | 27 | $438 |
| Smartleaf Asset Management LLC | 0.00% | Add +3.9% | 27 | $425 |
| Montag A & Associates Inc. | 0.00% | New | 16 | $260 |
| Clearstead Advisors, LLC | 0.00% | New | 4 | $65 |
| IFP Advisors, Inc | 0.00% | Add +0.0% | 4 | $65 |
| American National Bank & Trust | 0.00% | No change | 2 | $32 |
| Covestor Ltd | 0.00% | No change | 8 | $0 |
"% of holder's portfolio" is EWTX's weight in each manager's 13F, not the share of Edgewise Therapeutics Inc. the manager owns.