Gain TherapeuticsGANX
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 48 institutions reported holding Gain Therapeutics Inc. (GANX) in their 13F filings, up 10 from Q3 2025. 20 opened new positions and 10 sold out. The largest holders were Marshall Wace, LLP ($5.4M), Potomac Capital Management, Inc. ($3.3M) and Jones Financial Companies LLLP ($2.3M). 4 famous investors held it, including David Einhorn (0.1% of Greenlight Capital (DME Capital Management)'s portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Gain Therapeutics Inc.
- CUSIP
- 36269B105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 20 | $2.1M |
| Exits | 10 | $1.1M |
All 13F filers, Q3 2025 → Q4 2025: 3,534,498 shares bought and 823,400 shares sold, net +2,711,098 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 48 holders
| Marshall Wace, LLP | 0.01% | Add +849.3% | 1,662,293 | $5.4M |
| Potomac Capital Management, Inc. | 2.72% | — | 1,010,000 | $3.3M |
| Jones Financial Companies LLLP | 0.00% | Add +3.8% | 702,213 | $2.3M |
| Susquehanna International Group, LLP | 0.00% | Add +750.8% | 684,349 | $2.2M |
| Vanguard Group Inc. | 0.00% | Add +6.7% | 569,901 | $1.8M |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +78.5% | 568,645 | $1.8M |
| Greenlight Capital (DME Capital Management) | 0.06% | No change | 566,130 | $1.8M |
| Geode Capital Management, LLC | 0.00% | Add +15.6% | 397,942 | $1.3M |
| Jane Street Group, LLC | 0.00% | Add +234.5% | 242,328 | $780K |
| BlackRock, Inc. | 0.00% | Add +80.4% | 209,579 | $675K |
| Cresset Asset Management, LLC | 0.00% | New | 160,000 | $515K |
| State Street Corp. | 0.00% | Add +72.9% | 157,537 | $507K |
| Morgan Stanley | 0.00% | Reduce -5.2% | 147,591 | $475K |
| LPL Financial LLC | 0.00% | New | 106,550 | $343K |
| Northern Trust Corp. | 0.00% | Add +15.4% | 102,001 | $328K |
| UBS Group AG | 0.00% | Reduce -42.3% | 81,121 | $261K |
| Focus Partners Wealth | 0.00% | New | 77,855 | $251K |
| HRT Financial LP | 0.00% | Add +182.4% | 55,679 | $179K |
| Group One Trading LLC | 0.01% | Add +222.9% | 54,159 | $174K |
| Simplex Trading, LLC | 0.00% | New | 47,946 | $154K |
| Benedict Financial Advisors Inc. | 0.03% | Add +8.6% | 38,000 | $122K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 37,300 | $120K |
| Prelude Capital Management, LLC | 0.01% | No change | 35,820 | $115K |
| Goldman Sachs Group Inc. | 0.00% | New | 32,494 | $105K |
| Point72 Asset Management | 0.00% | New | 32,480 | $105K |
| Bridgeway Capital Management, LLC | 0.00% | No change | 30,004 | $97K |
| Lighthouse Investment Partners, LLC | 0.00% | New | 23,040 | $74K |
| Gsa Capital Partners LLP | 0.01% | New | 20,472 | $66K |
| Oliver Luxxe Assets LLC | 0.01% | New | 20,250 | $65K |
| Apollon Wealth Management, LLC | 0.00% | New | 19,825 | $64K |
| Renaissance Technologies | 0.00% | Reduce -86.2% | 17,400 | $56K |
| Wealthspire Advisors, LLC | 0.00% | New | 16,900 | $54K |
| Sandhill Capital Partners LLC | 0.00% | No change | 15,400 | $50K |
| Engineers Gate Manager LP | 0.00% | New | 14,617 | $47K |
| Millennium Management | 0.00% | New | 14,002 | $45K |
| Commonwealth Equity Services, LLC | 0.00% | New | 12,685 | $41K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | No change | 15,556 | $40K |
| Sprott Inc. | 0.00% | New | 12,000 | $39K |
| Kestra Advisory Services, LLC | 0.00% | No change | 12,000 | $39K |
| NewEdge Advisors, LLC | 0.00% | No change | 10,600 | $34K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +232.3% | 6,859 | $22K |
| MAI Capital Management | 0.00% | No change | 4,410 | $14K |
| Bank of America Corp. | 0.00% | Add +0.0% | 3,908 | $13K |
| Wells Fargo & Company | 0.00% | No change | 2,650 | $9K |
| BNP Paribas Financial Markets | 0.00% | New | 2,381 | $8K |
| FNY Investment Advisers, LLC | 0.00% | New | 2,000 | $6K |
| State of Wyoming | 0.00% | New | 1,438 | $5K |
| Larson Financial Group LLC | 0.00% | New | 10 | $32 |
"% of holder's portfolio" is GANX's weight in each manager's 13F, not the share of Gain Therapeutics Inc. the manager owns.