Fractyl HealthGUTS

13F holders, Q4 2025 (December 31)
97holders +23
33new positions
8sold out
6famous investors
$2.20avg. 13F price*

At the end of Q4 2025, 97 institutions reported holding Fractyl Health Inc. (GUTS) in their 13F filings, up 23 from Q3 2025. 33 opened new positions and 8 sold out. The largest holders were Nantahala Capital Management, LLC ($23.9M), Silverarc Capital Management, LLC ($21.6M) and 683 Capital Management, LLC ($13.3M). 6 famous investors held it, including Lee Ainslie (0.1% of Maverick Capital's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Fractyl Health Inc.
CUSIP
35168W103
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080100 Q1 2024: 42Q1 2024Q2 2024: 44Q2 2024Q3 2024: 61Q3 2024Q4 2024: 65Q4 2024Q1 2025: 65Q1 2025Q2 2025: 62Q2 2025Q3 2025: 74Q3 2025Q4 2025: 97Q4 2025Q1 2026: 83Q1 2026Q2 2026: 77Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions33$32.2M
Exits8$2.1M

All 13F filers, Q3 2025 → Q4 2025: 37,724,256 shares bought and 16,777,125 shares sold, net +20,947,131 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 97 holders

Nantahala Capital Management, LLC 1.43% Reduce -10.6% 10,846,440 $23.9M
Silverarc Capital Management, LLC 3.13% Reduce -7.2% 9,840,041 $21.6M
683 Capital Management, LLC 1.16% Add +30.1% 6,047,620 $13.3M
Vanguard Group Inc. 0.00% Add +213.8% 6,028,179 $13.3M
Marshall Wace, LLP 0.01% Add +234.9% 5,926,745 $13.0M
Woodline Partners LP 0.05% Add +0.0% 5,506,771 $12.1M
Catalio Capital Management, LP 2.14% Add +5.3% 5,491,866 $12.1M
General Catalyst Group Management, LLC 4.85% No change 4,884,193 $10.7M
Deer Management Co. LLC 1.02% No change 4,770,901 $10.5M
HCC Manager LLC 100.00% Reduce 0.0% 4,673,870 $10.3M
Maverick Capital 0.10% No change 4,248,492 $9.3M
Alyeska Investment Group, L.P. 0.02% Reduce -32.6% 3,809,523 $8.4M
Goldman Sachs Group Inc. 0.00% Add +598.4% 3,425,197 $7.5M
Pale Fire Capital SE 0.91% New 3,209,942 $7.1M
BlackRock, Inc. 0.00% Add +174.1% 2,083,318 $4.6M
Atom Investors LP 0.33% New 1,883,018 $4.1M
Renaissance Technologies 0.01% Add +139.9% 1,863,051 $4.1M
Jane Street Group, LLC 0.00% New 1,862,600 $4.1M
Millennium Management 0.00% Add +356.6% 1,861,418 $4.1M
M28 Capital Management LP 2.97% No change 1,856,117 $4.1M
Two Sigma Investments, LP 0.01% New 1,840,136 $4.0M
D. E. Shaw & Co. 0.00% Add +390.3% 1,442,745 $3.2M
Two Sigma Advisers, LP 0.01% New 1,298,700 $2.9M
Geode Capital Management, LLC 0.00% Add +328.5% 1,263,855 $2.8M
Bank of America Corp. 0.00% Add +1245.1% 1,192,236 $2.6M
Newtyn Management, LLC 0.26% New 1,134,021 $2.5M
UBS Group AG 0.00% Add +48.0% 1,113,982 $2.5M
Ikarian Capital, LLC 0.31% Reduce -38.9% 1,100,000 $2.4M
Logos Global Management LP 0.16% Add +120.0% 1,100,000 $2.4M
Massachusetts Financial Services Co. 0.00% Reduce -7.9% 852,344 $1.9M
CM Management, LLC 1.48% Add +33.3% 800,000 $1.8M
Susquehanna International Group, LLP 0.00% New 799,457 $1.8M
Morgan Stanley 0.00% Add +52.6% 656,482 $1.4M
Walleye Capital LLC 0.01% New 592,125 $1.3M
State Street Corp. 0.00% Add +1156.6% 512,700 $1.1M
Diametric Capital, LP 0.30% Add +300.7% 503,409 $1.1M
Burkehill Global Management, LP 0.08% No change 500,000 $1.1M
Brevan Howard Capital Management LP 0.02% New 464,738 $1.0M
Soleus Capital Management, L.P. 0.04% Reduce -84.0% 400,000 $880K
Rosalind Advisors, Inc. 0.31% Reduce -92.3% 385,731 $849K
Point72 Asset Management 0.00% Reduce -83.3% 365,173 $803K
Quadrature Capital Ltd 0.01% Add +2047.1% 290,714 $640K
Boothbay Fund Management, LLC 0.02% Reduce -58.0% 275,219 $605K
Barclays PLC 0.00% New 243,294 $535K
Citadel Advisors 0.00% Reduce -87.2% 228,985 $504K
Northern Trust Corp. 0.00% Add +1374.6% 215,877 $475K
PEAK6 LLC 0.01% Reduce -20.0% 200,000 $440K
Gsa Capital Partners LLP 0.04% Add +5.7% 189,176 $416K
OMERS ADMINISTRATION Corp 0.00% New 179,300 $394K
ExodusPoint Capital Management, LP 0.00% New 178,024 $392K
Hudson Bay Capital Management LP 0.00% New 171,816 $378K
Cerity Partners LLC 0.00% Add +1105.2% 163,500 $360K
Squarepoint Ops LLC 0.00% New 147,659 $325K
Shay Capital LLC 0.05% Reduce -52.1% 136,568 $300K
Quantbot Technologies LP 0.01% New 120,434 $265K
Qube Research & Technologies Ltd 0.00% Add +413.8% 117,631 $259K
Prelude Capital Management, LLC 0.01% Add +131.9% 80,597 $177K
Osaic Holdings, Inc. 0.00% Reduce -1.6% 75,476 $166K
Virtu Financial LLC 0.01% New 69,427 $153K
Conservest Capital Advisors, Inc. 0.01% No change 64,118 $141K
Cambridge Investment Research Advisors, Inc. 0.00% New 64,000 $141K
Balyasny Asset Management L.P. 0.00% New 60,219 $132K
Verition Fund Management LLC 0.00% New 54,910 $121K
Bridgeway Capital Management, LLC 0.00% Add +19.8% 54,500 $120K
XTX Topco Ltd 0.00% Add +12.8% 51,932 $114K
HighTower Advisors, LLC 0.00% No change 51,442 $113K
Schonfeld Strategic Advisors LLC 0.00% New 50,204 $110K
Susquehanna Portfolio Strategies, LLC 0.00% New 49,137 $108K
FNY Investment Advisers, LLC 0.03% Add +143.3% 48,650 $107K
Commonwealth Equity Services, LLC 0.00% New 38,700 $85K
Lighthouse Investment Partners, LLC 0.00% New 36,300 $80K
Citigroup Inc. 0.00% Add +16064.1% 35,076 $77K
Chicago Partners Investment Group LLC 0.00% No change 31,000 $65K
Jump Financial, LLC 0.00% New 26,000 $57K
Scientech Research LLC 0.02% Reduce -41.1% 18,006 $40K
Creative Planning 0.00% New 17,514 $39K
Centiva Capital, LP 0.00% Reduce -64.7% 17,419 $38K
Bronte Capital Management Pty Ltd. 0.00% New 16,905 $37K
Parkside Financial Bank & Trust 0.00% No change 16,304 $36K
Raymond James Financial Inc. 0.00% Add +18.7% 15,074 $33K
Tower Research Capital LLC (TRC) 0.00% Add +183.5% 14,768 $32K
R Squared Ltd 0.01% Add +31.6% 13,979 $31K
Victory Capital Management Inc. 0.00% New 13,059 $29K
LPL Financial LLC 0.00% No change 10,425 $23K
Bank of New York Mellon Corp 0.00% New 10,079 $22K
Larson Financial Group LLC 0.00% New 5,953 $13K
Triumph Capital Management 0.00% New 3,000 $7K
Millington Financial Advisors, LLC 0.00% New 12,562 $5K
St. Johns Investment Management Company, LLC 0.00% No change 1,980 $4K
Sound Income Strategies, LLC 0.00% Add +97.1% 1,971 $4K
CIBC Private Wealth Group LLC 0.00% New 1,200 $3K
JPMorgan Chase & Co. 0.00% Reduce -98.2% 934 $2K
BNP Paribas Financial Markets 0.00% Reduce -12.3% 802 $2K
Jones Financial Companies LLLP 0.00% No change 500 $1K
Allworth Financial LP 0.00% New 149 $328
SBI Securities Co., Ltd. 0.00% No change 120 $264
Optiver Holding B.V. 0.00% No change 14 $31

"% of holder's portfolio" is GUTS's weight in each manager's 13F, not the share of Fractyl Health Inc. the manager owns.