Disc MedicineIRON
13F holders, Q1 2025 (March 31)157holders +5
25new positions
21sold out
4famous investors
$49.76avg. 13F price*
At the end of Q1 2025, 157 institutions reported holding Disc Medicine Inc. (IRON) in their 13F filings, up 5 from Q4 2024. 25 opened new positions and 21 sold out. The largest holders were FMR LLC ($160.1M), Atlas Venture Life Science Advisors, LLC ($118.4M) and Wellington Management Group LLP ($116.3M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Disc Medicine Inc.
- CUSIP
- 254604101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 25 | $163.6M |
| Exits | 21 | $43.4M |
All 13F filers, Q4 2024 → Q1 2025: 8,749,009 shares bought and 2,239,949 shares sold, net +6,509,060 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 157 holders
| FMR LLC | 0.01% | Add +72.8% | 3,224,381 | $160.1M |
| Atlas Venture Life Science Advisors, LLC | 22.69% | Reduce -5.0% | 2,384,456 | $118.4M |
| Wellington Management Group LLP | 0.02% | Add +67.9% | 2,343,499 | $116.3M |
| BlackRock, Inc. | 0.00% | Add +12.6% | 2,094,560 | $104.0M |
| Frazier Life Sciences Management, L.P. | 3.99% | No change | 1,754,834 | $87.1M |
| Ra Capital Management, L.P. | 1.31% | New | 1,577,106 | $78.3M |
| Janus Henderson Group PLC | 0.04% | Add +16.9% | 1,423,259 | $74.5M |
| Orbimed Advisors LLC | 1.69% | Reduce -20.8% | 1,415,020 | $70.2M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -2.6% | 1,358,254 | $67.4M |
| Vanguard Group Inc. | 0.00% | Add +22.2% | 1,305,046 | $64.8M |
| Paradigm Biocapital Advisors LP | 2.77% | Reduce -19.1% | 1,210,971 | $60.1M |
| Siren, L.L.C. | 3.00% | New | 1,071,865 | $53.2M |
| Bain Capital Life Sciences Investors, LLC | 7.23% | No change | 983,500 | $48.8M |
| State Street Corp. | 0.00% | Add +19.5% | 918,567 | $45.6M |
| Deerfield Management Company, L.P. | 0.88% | Add +30.3% | 782,333 | $38.8M |
| JPMorgan Chase & Co. | 0.00% | Add +1144.5% | 759,338 | $37.7M |
| Geode Capital Management, LLC | 0.00% | Add +21.0% | 571,984 | $28.4M |
| Saturn V Capital Management LP | 12.98% | Add +1.7% | 518,177 | $25.7M |
| Woodline Partners LP | 0.16% | Add +26.6% | 502,230 | $24.9M |
| TCG Crossover Management, LLC | 3.15% | Reduce -4.5% | 465,257 | $23.1M |
| Armistice Capital, LLC | 0.58% | Add +22.5% | 436,000 | $21.6M |
| Logos Global Management LP | 3.48% | Add +97.2% | 394,342 | $19.6M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | Reduce -14.3% | 300,000 | $14.9M |
| Foresite Capital Management V, LLC | 16.94% | No change | 299,069 | $14.8M |
| Checkpoint Capital L.P. | 6.63% | Add +31.5% | 243,311 | $12.1M |
| Silverarc Capital Management, LLC | 2.45% | Add +114.2% | 236,471 | $11.7M |
| D. E. Shaw & Co. | 0.01% | Add +170.5% | 219,603 | $10.9M |
| Northern Trust Corp. | 0.00% | Add +11.7% | 208,813 | $10.4M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +18.0% | 194,725 | $9.7M |
| Victory Capital Management Inc. | 0.01% | Reduce -18.0% | 193,664 | $9.6M |
| Renaissance Technologies | 0.01% | Add +121.3% | 191,220 | $9.5M |
| Eventide Asset Management, LLC | 0.18% | New | 181,818 | $9.0M |
| Morgan Stanley | 0.00% | Add +13.5% | 170,210 | $8.4M |
| Perceptive Advisors LLC | 0.26% | New | 150,000 | $7.4M |
| Nantahala Capital Management, LLC | 0.61% | Reduce -1.1% | 148,391 | $7.4M |
| Blue Owl Capital Holdings LP | 2.25% | Add +16.6% | 140,260 | $7.0M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -0.2% | 139,393 | $6.9M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -23.9% | 130,751 | $6.5M |
| Pictet Asset Management Holding SA | 0.01% | Add +0.7% | 130,386 | $6.5M |
| Nuveen, LLC | 0.00% | — | 112,717 | $5.6M |
| Millennium Management | 0.01% | Add +1277.1% | 108,499 | $5.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +3.7% | 96,557 | $4.8M |
| Schroder Investment Management Group | 0.00% | Reduce -4.6% | 87,290 | $4.6M |
| Opaleye Management Inc. | 0.96% | New | 85,000 | $4.2M |
| Raymond James Financial Inc. | 0.00% | Reduce -5.4% | 83,276 | $4.1M |
| Patient Square Capital LP | 1.70% | Add +47.2% | 83,000 | $4.1M |
| Montanova Capital, LLC | 0.16% | New | 80,000 | $4.0M |
| Baker Bros. Advisors LP | 0.04% | No change | 77,050 | $3.8M |
| Sio Capital Management, LLC | 1.11% | No change | 73,511 | $3.6M |
| UBS Group AG | 0.00% | Add +198.4% | 72,628 | $3.6M |
| Ensign Peak Advisors, Inc | 0.01% | Add +81.3% | 72,513 | $3.6M |
| Susquehanna International Group, LLP | 0.01% | Add +146.3% | 70,941 | $3.5M |
| Ameriprise Financial Inc. | 0.00% | Add +1186.6% | 67,905 | $3.4M |
| Bank of New York Mellon Corp | 0.00% | Add +10.9% | 63,503 | $3.2M |
| Citadel Advisors | 0.00% | Reduce -89.5% | 62,214 | $3.1M |
| Exome Asset Management LLC | 2.74% | Reduce -10.7% | 61,656 | $3.1M |
| Bank of America Corp. | 0.00% | Add +52.2% | 53,808 | $2.7M |
| Barclays PLC | 0.00% | Add +14.1% | 45,708 | $2.3M |
| Twinbeech Capital LP | 0.04% | New | 45,448 | $2.3M |
| Citigroup Inc. | 0.00% | Add +0.8% | 42,975 | $2.1M |
| Zimmer Partners, LP | 0.04% | Add +29.6% | 42,900 | $2.1M |
| TD Asset Management Inc | 0.00% | Reduce -5.5% | 42,448 | $2.1M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +5.5% | 40,585 | $2.0M |
| Swiss National Bank | 0.00% | Add +11.5% | 35,900 | $1.8M |
| Rafferty Asset Management, LLC | 0.01% | Add +22.7% | 34,041 | $1.7M |
| Rhumbline Advisers | 0.00% | Add +10.7% | 32,144 | $1.6M |
| Alps Advisors Inc. | 0.01% | Add +5.9% | 25,479 | $1.3M |
| Ghisallo Capital Management LLC | 0.11% | New | 25,000 | $1.2M |
| PNC Financial Services Group, Inc. | 0.00% | No change | 23,700 | $1.2M |
| Wells Fargo & Company | 0.00% | Add +9.9% | 22,836 | $1.1M |
| Atom Investors LP | 0.14% | New | 22,561 | $1.1M |
| Walleye Capital LLC | 0.01% | Reduce -18.3% | 22,075 | $1.1M |
| Alliancebernstein L.P. | 0.00% | No change | 21,060 | $1.0M |
| Legal & General Group Plc | 0.00% | Add +15.4% | 20,415 | $1.0M |
| California State Teachers Retirement System | 0.00% | Add +29.8% | 20,152 | $1.0M |
| Prelude Capital Management, LLC | 0.09% | Add +0.2% | 18,200 | $903K |
| Engineers Gate Manager LP | 0.01% | Add +30.8% | 16,810 | $834K |
| Algert Global LLC | 0.02% | No change | 16,337 | $811K |
| Harvest Investment Services, LLC | 0.21% | Reduce -1.5% | 15,382 | $764K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +22.8% | 15,138 | $756K |
| Deutsche Bank AG | 0.00% | Reduce -8.6% | 14,705 | $730K |
| Teachers Retirement System of the State of Kentucky | 0.01% | Reduce -14.0% | 14,628 | $726K |
| SG Americas Securities, LLC | 0.00% | Add +77.4% | 14,329 | $711K |
| Invesco Ltd. | 0.00% | Add +27.1% | 13,834 | $687K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.02% | Reduce -4.5% | 13,621 | $676K |
| ExodusPoint Capital Management, LP | 0.01% | New | 13,565 | $673K |
| MetLife Investment Management, LLC | 0.00% | Add +10.9% | 13,454 | $668K |
| Aquatic Capital Management LLC | 0.02% | New | 12,188 | $605K |
| State of Wisconsin Investment Board | 0.00% | Reduce -1.9% | 11,983 | $595K |
| Corebridge Financial, Inc. | 0.00% | Add +14.0% | 11,180 | $555K |
| Intech Investment Management LLC | 0.01% | Add +38.8% | 10,948 | $543K |
| Lion Point Capital, LP | 3.36% | No change | 10,600 | $526K |
| BNP Paribas Financial Markets | 0.00% | Add +101.1% | 10,286 | $511K |
| Trexquant Investment LP | 0.00% | Reduce -33.5% | 8,556 | $425K |
| Quantbot Technologies LP | 0.01% | Add +189025.0% | 7,565 | $376K |
| Schonfeld Strategic Advisors LLC | 0.00% | Add +54.1% | 7,552 | $375K |
| Sofinnova Investments, Inc. | 0.03% | Reduce -67.1% | 7,485 | $372K |
| Profund Advisors LLC | 0.02% | Add +29.3% | 7,160 | $355K |
| STRS Ohio | 0.00% | Add +677.8% | 7,000 | $347K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +9.9% | 6,934 | $344K |
| ProShare Advisors LLC | 0.00% | Reduce -6.7% | 6,500 | $323K |
| HighVista Strategies LLC | 0.12% | No change | 6,458 | $321K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | New | 6,391 | $317K |
| New York State Common Retirement Fund | 0.00% | No change | 6,276 | $312K |
| Voya Investment Management LLC | 0.00% | Add +1.5% | 5,951 | $295K |
| Bank of Montreal | 0.00% | New | 5,851 | $290K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.00% | — | 5,800 | $288K |
| Arizona State Retirement System | 0.00% | Add +12.5% | 5,315 | $264K |
| Cibc World Markets Corp. | 0.00% | New | 5,064 | $251K |
| Teacher Retirement System of Texas | 0.00% | Add +2.2% | 4,965 | $246K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +19.1% | 4,890 | $243K |
| Verition Fund Management LLC | 0.00% | New | 4,279 | $212K |
| Graham Capital Management, L.P. | 0.01% | New | 4,217 | $209K |
| Fiduciary Trust Co | 0.00% | No change | 4,051 | $201K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 4,050 | $201K |
| KLP Kapitalforvaltning As | 0.00% | No change | 3,700 | $184K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +7.3% | 3,076 | $153K |
| Virtus Investment Advisers, LLC | 0.04% | New | 2,556 | $127K |
| Ameritas Investment Partners, Inc. | 0.00% | Add +15.5% | 2,309 | $115K |
| Simplex Trading, LLC | 0.00% | New | 1,840 | $91K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +16.6% | 1,157 | $61K |
| US Bancorp \de | 0.00% | Add +2.3% | 1,203 | $60K |
| Royal Bank of Canada | 0.00% | Reduce -51.0% | 1,198 | $59K |
| Caitong International Asset Management Co., Ltd | 0.04% | Add +13428.6% | 947 | $47K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -0.2% | 823 | $41K |
| Amalgamated Bank | 0.00% | Add +38.6% | 787 | $39K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 762 | $38K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 730 | $36K |
| Aster Capital Management (DIFC) Ltd | 0.01% | Add +968.5% | 577 | $32K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 525 | $26K |
| Sterling Capital Management LLC | 0.00% | Reduce -37.8% | 352 | $17K |
| Cwm, LLC | 0.00% | Add +316.3% | 333 | $17K |
| AlphaQuest LLC | 0.00% | Reduce -48.0% | 327 | $16K |
| GAMMA Investing LLC | 0.00% | Add +4.6% | 250 | $12K |
| Daiwa Securities Group Inc. | 0.00% | No change | 113 | $6K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -2.4% | 81 | $4K |
| Lindbrook Capital, LLC | 0.00% | New | 58 | $3K |
| Clearstead Advisors, LLC | 0.00% | No change | 46 | $2K |
| Coldstream Capital Management Inc. | 0.00% | New | 46 | $2K |
| Rothschild Investment LLC | 0.00% | Add +50.0% | 45 | $2K |
| Bessemer Group Inc. | 0.00% | Reduce -52.0% | 12 | $1K |
| Fortitude Family Office, LLC | 0.00% | No change | 20 | $993 |
| Signaturefd, LLC | 0.00% | New | 18 | $894 |
| Comerica Bank | 0.00% | Add +13.3% | 17 | $839 |
| Wolff Wiese Magana LLC | 0.00% | No change | 14 | $695 |
| Assetmark, Inc. | 0.00% | New | 12 | $596 |
| Stephens Consulting, LLC | 0.00% | New | 10 | $497 |
| Russell Investments Group, Ltd. | 0.00% | No change | 10 | $496 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 10 | $496 |
| CoreCap Advisors, LLC | 0.00% | Reduce -67.9% | 9 | $447 |
| True Wealth Design, LLC | 0.00% | Add +600.0% | 7 | $348 |
| J.Safra Asset Management Corp | 0.00% | New | 6 | $298 |
| SBI Securities Co., Ltd. | 0.00% | No change | 6 | $298 |
| Amundi | 0.00% | No change | 5 | $229 |
| Parallel Advisors, LLC | 0.00% | Add +300.0% | 4 | $199 |
| IFP Advisors, Inc | 0.00% | No change | 1 | $50 |
| Covestor Ltd | 0.00% | No change | 2 | $0 |
"% of holder's portfolio" is IRON's weight in each manager's 13F, not the share of Disc Medicine Inc. the manager owns.