Iteos TherapeuticsITOS
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 137 institutions reported holding Iteos Therapeutics Inc. (ITOS) in their 13F filings, up 5 from Q1 2025. 39 opened new positions and 35 sold out. The largest holders were EcoR1 Capital, LLC ($106.6M), BlackRock, Inc. ($45.6M) and Tang Capital Management LLC ($38.2M). 7 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Iteos Therapeutics Inc.
- CUSIP
- 46565G104
- Latest filing quarter
- Q3 2025
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $173.6M |
| Exits | 35 | $93.1M |
All 13F filers, Q1 2025 → Q2 2025: 20,888,409 shares bought and 20,040,698 shares sold, net +847,711 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 137 holders
| EcoR1 Capital, LLC | 6.32% | New | 10,688,978 | $106.6M |
| BlackRock, Inc. | 0.00% | Add +1.4% | 4,574,537 | $45.6M |
| Tang Capital Management LLC | 1.93% | Add +42.3% | 3,826,692 | $38.2M |
| Vanguard Group Inc. | 0.00% | Reduce -3.6% | 1,664,161 | $16.6M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -29.5% | 832,761 | $8.3M |
| Boxer Capital Management, LLC | 4.14% | New | 825,000 | $8.2M |
| Geode Capital Management, LLC | 0.00% | Add +8.2% | 703,467 | $7.0M |
| Orbimed Advisors LLC | 0.18% | New | 700,000 | $7.0M |
| Marshall Wace, LLP | 0.01% | Add +411.6% | 611,649 | $6.1M |
| Renaissance Technologies | 0.01% | Reduce -6.7% | 602,100 | $6.0M |
| JPMorgan Chase & Co. | 0.00% | Reduce -69.7% | 601,363 | $6.0M |
| Nantahala Capital Management, LLC | 0.42% | New | 596,666 | $5.9M |
| State Street Corp. | 0.00% | Add +2.2% | 594,555 | $5.9M |
| DLD Asset Management, LP | 2.78% | New | 576,655 | $5.7M |
| Newtyn Management, LLC | 0.86% | New | 567,416 | $5.7M |
| LMR Partners LLP | 0.13% | New | 550,000 | $5.5M |
| Alyeska Investment Group, L.P. | 0.02% | New | 500,000 | $5.0M |
| Almitas Capital LLC | 1.23% | Add +77.1% | 487,204 | $4.9M |
| Millennium Management | 0.00% | Add +37.0% | 477,189 | $4.8M |
| Morgan Stanley | 0.00% | Add +71.0% | 429,340 | $4.3M |
| Stonepine Capital Management, LLC | 3.04% | Add +181.8% | 310,033 | $3.1M |
| Bank of America Corp. | 0.00% | Add +71.4% | 308,660 | $3.1M |
| Rangeley Capital, LLC | 3.92% | New | 302,080 | $3.0M |
| Silver Point Capital L.P. | 0.26% | New | 290,000 | $2.9M |
| Northern Trust Corp. | 0.00% | Add +3.3% | 258,369 | $2.6M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +5.4% | 246,086 | $2.5M |
| AQR Capital Management | 0.00% | Add +5.1% | 237,805 | $2.4M |
| Alpine Global Management, LLC | 0.58% | New | 225,000 | $2.2M |
| Shay Capital LLC | 0.48% | New | 210,516 | $2.1M |
| Ameriprise Financial Inc. | 0.00% | Add +5.0% | 207,787 | $2.1M |
| Diadema Partners LP | 1.28% | New | 206,200 | $2.1M |
| Susquehanna Portfolio Strategies, LLC | 0.04% | New | 204,708 | $2.0M |
| Acadian Asset Management LLC | 0.00% | Reduce -65.2% | 186,692 | $1.9M |
| Royal Bank of Canada | 0.00% | Add +10769.5% | 185,760 | $1.9M |
| Peapod Lane Capital LLC | 1.69% | Add +24.8% | 169,287 | $1.7M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -73.5% | 155,351 | $1.5M |
| Wellington Management Group LLP | 0.00% | Add +10.6% | 154,963 | $1.5M |
| Nuveen, LLC | 0.00% | Reduce -49.1% | 154,424 | $1.5M |
| Verition Fund Management LLC | 0.01% | Add +241.2% | 150,648 | $1.5M |
| GABELLI & Co INVESTMENT ADVISERS, INC. | 0.23% | New | 146,450 | $1.5M |
| Susquehanna International Group, LLP | 0.00% | Add +296.8% | 144,080 | $1.4M |
| DAFNA Capital Management LLC | 0.39% | Reduce -34.0% | 140,847 | $1.4M |
| Barclays PLC | 0.00% | Reduce -2.3% | 125,996 | $1.3M |
| Gabelli Funds LLC | 0.01% | New | 120,593 | $1.2M |
| Eversept Partners, LP | 0.11% | Reduce -50.4% | 109,324 | $1.1M |
| Simplex Trading, LLC | 0.03% | New | 103,212 | $1.0M |
| Citadel Advisors | 0.00% | Reduce -92.0% | 94,256 | $940K |
| Invesco Ltd. | 0.00% | Reduce -4.9% | 81,035 | $808K |
| American Century Companies Inc. | 0.00% | Add +5.9% | 78,949 | $787K |
| Bank of New York Mellon Corp | 0.00% | Add +19.7% | 77,547 | $773K |
| Dynamic Technology Lab Private Ltd | 0.10% | Add +587.3% | 77,371 | $771K |
| Algert Global LLC | 0.02% | Reduce -6.8% | 74,477 | $743K |
| Campbell & CO Investment Adviser LLC | 0.05% | New | 72,262 | $720K |
| HSBC Holdings PLC | 0.00% | Reduce -11.0% | 68,533 | $686K |
| Susquehanna Fundamental Investments, LLC | 0.02% | Reduce -21.0% | 66,779 | $666K |
| FNY Investment Advisers, LLC | 0.28% | New | 65,000 | $648K |
| Engineers Gate Manager LP | 0.01% | Add +61.8% | 59,559 | $594K |
| Man Group plc | 0.00% | Add +160.8% | 58,768 | $586K |
| Regency Capital Management Inc.\DE | 0.30% | New | 58,000 | $578K |
| Thrivent Financial for Lutherans | 0.00% | Add +15.1% | 56,556 | $563K |
| Fisher Asset Management | 0.00% | No change | 55,722 | $556K |
| KLP Kapitalforvaltning As | 0.00% | Add +42.4% | 55,400 | $552K |
| Clearline Capital LP | 0.05% | New | 55,013 | $548K |
| D. E. Shaw & Co. | 0.00% | Reduce -48.7% | 53,432 | $533K |
| FMR LLC | 0.00% | Add +1259.6% | 52,740 | $526K |
| Rhumbline Advisers | 0.00% | Add +12.4% | 48,882 | $487K |
| State of Wisconsin Investment Board | 0.00% | New | 48,096 | $480K |
| Persistent Asset Partners Ltd | 0.41% | New | 47,512 | $474K |
| Ieq Capital, LLC | 0.00% | Add +207.8% | 45,399 | $453K |
| UBS Group AG | 0.00% | Add +68.7% | 44,288 | $442K |
| Alliancebernstein L.P. | 0.00% | Add +35.9% | 44,180 | $440K |
| Prudential Financial Inc. | 0.00% | Reduce -39.4% | 42,861 | $427K |
| Oxford Asset Management LLP | 0.14% | Add +110.0% | 41,771 | $416K |
| Citigroup Inc. | 0.00% | Add +107.2% | 39,742 | $396K |
| Prelude Capital Management, LLC | 0.04% | Add +140.8% | 39,349 | $392K |
| Vazirani Asset Management LLC | 1.33% | New | 35,000 | $349K |
| XTX Topco Ltd | 0.01% | New | 34,777 | $347K |
| Deutsche Bank AG | 0.00% | Reduce -0.1% | 33,556 | $335K |
| Bluefin Capital Management, LLC | 0.24% | New | 30,530 | $304K |
| AlphaQuest LLC | 0.03% | Reduce -5.6% | 29,019 | $289K |
| Nebula Research & Development LLC | 0.02% | New | 28,909 | $288K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | Add +56.6% | 28,375 | $283K |
| ADAR1 Capital Management, LLC | 0.04% | Reduce -73.4% | 26,937 | $269K |
| Sandia Investment Management LP | 0.65% | New | 24,865 | $248K |
| Proficio Capital Partners LLC | 0.02% | New | 24,865 | $248K |
| Jane Street Group, LLC | 0.00% | Add +7.3% | 22,999 | $229K |
| Caption Management, LLC | 0.02% | Reduce -85.7% | 22,157 | $221K |
| Intech Investment Management LLC | 0.00% | Add +13.4% | 20,806 | $207K |
| Alps Advisors Inc. | 0.00% | Reduce -27.9% | 20,653 | $206K |
| Graham Capital Management, L.P. | 0.01% | Reduce -49.3% | 20,637 | $206K |
| Wells Fargo & Company | 0.00% | Add +18.8% | 20,192 | $201K |
| Two Sigma Advisers, LP | 0.00% | New | 18,000 | $179K |
| MetLife Investment Management, LLC | 0.00% | Add +21.1% | 17,001 | $170K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +2.3% | 16,351 | $163K |
| Tudor Investment Corporation | 0.00% | Reduce -12.7% | 15,415 | $154K |
| Bailard, Inc. | 0.00% | New | 15,200 | $152K |
| T. Rowe Price Associates Inc. | 0.00% | Add +20.8% | 14,969 | $150K |
| Axq Capital, LP | 0.04% | New | 13,860 | $138K |
| Cwm, LLC | 0.00% | Add +40.4% | 12,013 | $120K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +5.4% | 11,466 | $114K |
| Aigen Investment Management, LP | 0.02% | New | 11,291 | $113K |
| Quantinno Capital Management LP | 0.00% | New | 10,305 | $103K |
| Virtus Investment Advisers, LLC | 0.03% | Reduce -54.4% | 9,422 | $94K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +4.9% | 7,687 | $77K |
| STRS Ohio | 0.00% | Add +36.5% | 7,100 | $71K |
| BNP Paribas Financial Markets | 0.00% | Add +0.8% | 6,864 | $68K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 5,213 | $52K |
| New York State Common Retirement Fund | 0.00% | No change | 5,109 | $51K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +139.0% | 3,953 | $39K |
| Legal & General Group Plc | 0.00% | Add +14.5% | 2,717 | $27K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 2,444 | $24K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -94.8% | 2,328 | $23K |
| California State Teachers Retirement System | 0.00% | No change | 1,967 | $20K |
| Nisa Investment Advisors, LLC | 0.00% | Add +959.6% | 1,939 | $19K |
| PNC Financial Services Group, Inc. | 0.00% | Add +90.2% | 1,537 | $15K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +21.0% | 1,479 | $15K |
| Caitong International Asset Management Co., Ltd | 0.01% | Add +117.2% | 1,073 | $11K |
| GF Fund Management Co. LTD. | 0.00% | No change | 935 | $9K |
| Amalgamated Bank | 0.00% | No change | 825 | $8K |
| Sterling Capital Management LLC | 0.00% | Add +63.8% | 752 | $7K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +622.7% | 636 | $6K |
| Brooklyn Investment Group | 0.00% | New | 556 | $6K |
| Essential Partners LLC | 0.00% | — | 378 | $4K |
| IFP Advisors, Inc | 0.00% | Add +721.4% | 230 | $2K |
| US Bancorp \de | 0.00% | Reduce -76.6% | 149 | $1K |
| True Wealth Design, LLC | 0.00% | Reduce -24.2% | 125 | $1K |
| Raymond James Financial Inc. | 0.00% | New | 125 | $1K |
| Farther Finance Advisors, LLC | 0.00% | New | 120 | $1K |
| Harbor Capital Advisors, Inc. | 0.00% | Reduce -77.9% | 148 | $1K |
| Hantz Financial Services, Inc. | 0.00% | No change | 100 | $1K |
| Daiwa Securities Group Inc. | 0.00% | No change | 121 | $1K |
| GAMMA Investing LLC | 0.00% | Reduce -78.0% | 76 | $758 |
| Osaic Holdings, Inc. | 0.00% | Add +40.0% | 56 | $558 |
| Raffa Wealth Management, LLC | 0.00% | No change | 52 | $518 |
| Allworth Financial LP | 0.00% | New | 40 | $399 |
| Clearstead Advisors, LLC | 0.00% | New | 13 | $130 |
| Covestor Ltd | 0.00% | Add +83.3% | 11 | $0 |
"% of holder's portfolio" is ITOS's weight in each manager's 13F, not the share of Iteos Therapeutics Inc. the manager owns.