Kymera TherapeuticsKYMR
13F holders, Q4 2025 (December 31)255holders +45
56new positions
15sold out
5famous investors
$77.80avg. 13F price*
At the end of Q4 2025, 255 institutions reported holding Kymera Therapeutics Inc. (KYMR) in their 13F filings, up 45 from Q3 2025. 56 opened new positions and 15 sold out. The largest holders were FMR LLC ($694.7M), Baker Bros. Advisors LP ($673.6M) and Avoro Capital Advisors LLC ($581.6M). 5 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Ron Baron (0.0% of Baron Capital (BAMCO)'s portfolio).
- Company
- Kymera Therapeutics Inc.
- CUSIP
- 501575104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 56 | $109.3M |
| Exits | 15 | $17.7M |
All 13F filers, Q3 2025 → Q4 2025: 14,257,593 shares bought and 5,159,738 shares sold, net +9,097,855 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 255 holders
| FMR LLC | 0.04% | Add +51.9% | 8,928,574 | $694.7M |
| Baker Bros. Advisors LP | 3.96% | Add +30.2% | 8,657,242 | $673.6M |
| Avoro Capital Advisors LLC | 5.72% | Add +17.7% | 7,474,747 | $581.6M |
| Vanguard Group Inc. | 0.01% | Add +15.6% | 6,267,644 | $487.7M |
| T. Rowe Price Associates Inc. | 0.05% | Add +20.8% | 6,159,335 | $479.3M |
| BVF Inc. | 14.41% | No change | 5,502,710 | $428.2M |
| BlackRock, Inc. | 0.01% | Add +14.6% | 5,004,095 | $389.4M |
| Atlas Venture Life Science Advisors, LLC | 41.91% | Reduce -4.8% | 4,659,874 | $362.6M |
| Wellington Management Group LLP | 0.06% | Reduce -15.1% | 4,412,933 | $343.4M |
| Siren, L.L.C. | 7.63% | Reduce -4.1% | 3,286,830 | $255.7M |
| State Street Corp. | 0.01% | Add +9.4% | 2,209,837 | $171.9M |
| Capital Research Global Investors | 0.02% | Add +23.7% | 1,560,791 | $121.4M |
| Geode Capital Management, LLC | 0.01% | Add +11.0% | 1,417,389 | $110.3M |
| Driehaus Capital Management LLC | 0.57% | Add +13.9% | 1,069,238 | $83.2M |
| Alliancebernstein L.P. | 0.02% | Add +1852.2% | 952,065 | $74.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +5.6% | 912,498 | $71.0M |
| Merck & Co., Inc. | 21.75% | No change | 772,165 | $60.1M |
| Federated Hermes, Inc. | 0.10% | Add +36.7% | 763,920 | $59.4M |
| Holocene Advisors, LP | 0.12% | Reduce -9.4% | 761,209 | $59.2M |
| Commodore Capital LP | 3.88% | No change | 750,000 | $58.4M |
| Goldman Sachs Group Inc. | 0.01% | Add +4.1% | 740,306 | $57.6M |
| UBS Group AG | 0.01% | Add +13.6% | 737,032 | $57.3M |
| Frontier Capital Management Co. LLC | 0.53% | Add +22.8% | 635,957 | $49.5M |
| T. Rowe Price Investment Management, Inc. | 0.03% | Add +3.0% | 629,745 | $49.0M |
| Eventide Asset Management, LLC | 0.76% | Reduce -2.8% | 626,430 | $48.7M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -14.7% | 624,027 | $48.6M |
| Deerfield Management Company, L.P. | 0.64% | Reduce -1.9% | 561,170 | $43.7M |
| Octagon Capital Advisors LP | 5.21% | Add +48.6% | 535,000 | $41.6M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +13.0% | 497,026 | $38.7M |
| Rock Springs Capital Management LP | 1.99% | Add +10.3% | 496,871 | $38.7M |
| Jennison Associates LLC | 0.02% | Reduce -51.7% | 496,665 | $38.6M |
| Pictet Asset Management Holding SA | 0.04% | Add +39.3% | 483,199 | $37.8M |
| Northern Trust Corp. | 0.00% | Add +6.8% | 467,022 | $36.3M |
| Braidwell LP | 1.35% | Add +64.2% | 454,259 | $35.3M |
| Adage Capital Partners Gp, L.L.C. | 0.05% | Add +80.7% | 430,000 | $33.5M |
| Two Sigma Advisers, LP | 0.06% | Add +0.4% | 373,800 | $29.1M |
| Alyeska Investment Group, L.P. | 0.08% | Reduce -39.5% | 371,889 | $28.9M |
| Franklin Resources Inc. | 0.01% | Add +1019.9% | 354,575 | $27.6M |
| Bank of America Corp. | 0.00% | Add +82.0% | 338,999 | $26.4M |
| Boxer Capital Management, LLC | 5.61% | Add +3.1% | 329,100 | $25.6M |
| Massachusetts Financial Services Co. | 0.01% | Reduce -33.5% | 289,404 | $22.5M |
| Nextech Invest Ltd. | 2.10% | Reduce -18.2% | 278,896 | $21.7M |
| Morgan Stanley | 0.00% | Reduce -27.5% | 274,018 | $21.3M |
| Two Sigma Investments, LP | 0.03% | Reduce -38.2% | 265,532 | $20.7M |
| RTW Investments, LP | 0.19% | New | 240,000 | $18.7M |
| Gilder Gagnon Howe & Co. LLC | 0.20% | Reduce -2.8% | 239,916 | $18.7M |
| Deer Management Co. LLC | 1.75% | Reduce -29.2% | 230,811 | $18.0M |
| TD Asset Management Inc | 0.01% | Add +5.7% | 221,178 | $17.2M |
| First Turn Management, LLC | 1.84% | Reduce -25.7% | 206,445 | $16.1M |
| Woodline Partners LP | 0.06% | Reduce -17.9% | 203,585 | $15.8M |
| Candriam S.C.A. | 0.08% | Add +5.2% | 201,672 | $15.7M |
| Polar Capital Holdings Plc | 0.07% | Reduce -49.4% | 200,946 | $15.6M |
| Bank of New York Mellon Corp | 0.00% | Add +26.4% | 192,748 | $15.0M |
| TimesSquare Capital Management, LLC | 0.22% | New | 189,900 | $14.8M |
| Point72 Asset Management | 0.02% | Reduce -0.4% | 173,147 | $13.5M |
| Citadel Advisors | 0.01% | Add +282.2% | 159,865 | $12.4M |
| Squarepoint Ops LLC | 0.03% | Reduce -54.6% | 159,426 | $12.4M |
| Foresite Capital Management VI LLC | 3.44% | No change | 146,332 | $11.4M |
| Barclays PLC | 0.00% | Reduce -9.4% | 140,507 | $10.9M |
| Patient Square Capital LP | 2.32% | Add +50.1% | 139,000 | $10.8M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +7.4% | 135,894 | $10.6M |
| Eagle Health Investments LP | 2.33% | New | 136,300 | $10.6M |
| JPMorgan Chase & Co. | 0.00% | Reduce -31.8% | 131,353 | $10.2M |
| Logos Global Management LP | 0.67% | Reduce -48.0% | 130,000 | $10.1M |
| Nuveen, LLC | 0.00% | Add +17.2% | 125,050 | $9.7M |
| Invesco Ltd. | 0.00% | Add +46.3% | 116,747 | $9.1M |
| WCM Investment Management, LLC | 0.02% | New | 105,194 | $8.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Reduce -2.0% | 105,554 | $8.2M |
| Monashee Investment Management LLC | 4.60% | New | 100,000 | $7.8M |
| Ensign Peak Advisors, Inc | 0.01% | Add +3.4% | 95,047 | $7.4M |
| Swiss National Bank | 0.00% | Add +15.4% | 94,200 | $7.3M |
| Armistice Capital, LLC | 0.15% | New | 81,165 | $6.3M |
| Deutsche Bank AG | 0.00% | Add +9.8% | 79,843 | $6.2M |
| Burkehill Global Management, LP | 0.40% | No change | 75,000 | $5.8M |
| Yiheng Capital Management, L.P. | 2.49% | Reduce -40.1% | 73,440 | $5.7M |
| Rhumbline Advisers | 0.00% | Reduce -2.5% | 72,304 | $5.6M |
| Perceptive Advisors LLC | 0.10% | Reduce -58.8% | 69,935 | $5.4M |
| Victory Capital Management Inc. | 0.00% | Add +114.4% | 67,086 | $5.2M |
| Wells Fargo & Company | 0.00% | Add +107.4% | 66,489 | $5.2M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.01% | Add +15622.1% | 64,775 | $5.0M |
| Alps Advisors Inc. | 0.03% | New | 64,723 | $5.0M |
| First Trust Advisors LP | 0.00% | Reduce -21.4% | 58,862 | $4.6M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -14.1% | 58,653 | $4.6M |
| Neuberger Berman Group LLC | 0.00% | New | 58,482 | $4.6M |
| Informed Momentum Co LLC | 0.49% | Reduce -2.0% | 56,455 | $4.4M |
| Nicholas Investment Partners, LP | 0.36% | Add +6.0% | 55,788 | $4.3M |
| Verition Fund Management LLC | 0.02% | Add +72.6% | 54,319 | $4.2M |
| Schroder Investment Management Group | 0.00% | Reduce -14.6% | 52,671 | $4.1M |
| Comerica Bank | 0.02% | Reduce -3.1% | 49,812 | $3.9M |
| Russell Investments Group, Ltd. | 0.00% | Add +142.1% | 45,977 | $3.6M |
| California State Teachers Retirement System | 0.00% | Add +12.4% | 45,742 | $3.6M |
| Legal & General Group Plc | 0.00% | Reduce -0.2% | 43,428 | $3.4M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +51.5% | 40,777 | $3.2M |
| Dark Forest Capital Management LP | 0.14% | Add +26.3% | 39,207 | $3.1M |
| Moody Aldrich Partners LLC | 0.56% | Add +33.3% | 38,535 | $3.0M |
| Marshall Wace, LLP | 0.00% | Reduce -89.4% | 38,022 | $3.0M |
| Y-Intercept (Hong Kong) Ltd | 0.06% | New | 36,429 | $2.8M |
| Silverarc Capital Management, LLC | 0.39% | New | 34,589 | $2.7M |
| State of New Jersey Common Pension Fund D | 0.01% | New | 33,538 | $2.6M |
| Sio Capital Management, LLC | 0.42% | New | 32,235 | $2.5M |
"% of holder's portfolio" is KYMR's weight in each manager's 13F, not the share of Kymera Therapeutics Inc. the manager owns.