Kymera TherapeuticsKYMR

13F holders, Q4 2025 (December 31)
255holders +45
56new positions
15sold out
5famous investors
$77.80avg. 13F price*

At the end of Q4 2025, 255 institutions reported holding Kymera Therapeutics Inc. (KYMR) in their 13F filings, up 45 from Q3 2025. 56 opened new positions and 15 sold out. The largest holders were FMR LLC ($694.7M), Baker Bros. Advisors LP ($673.6M) and Avoro Capital Advisors LLC ($581.6M). 5 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Ron Baron (0.0% of Baron Capital (BAMCO)'s portfolio).

Company
Kymera Therapeutics Inc.
CUSIP
501575104
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300 Q1 2024: 164Q1 2024Q2 2024: 157Q2 2024Q3 2024: 176Q3 2024Q4 2024: 180Q4 2024Q1 2025: 173Q1 2025Q2 2025: 210Q2 2025Q3 2025: 210Q3 2025Q4 2025: 255Q4 2025Q1 2026: 256Q1 2026Q2 2026: 276Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions56$109.3M
Exits15$17.7M

All 13F filers, Q3 2025 → Q4 2025: 14,257,593 shares bought and 5,159,738 shares sold, net +9,097,855 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 255 holders

FMR LLC 0.04% Add +51.9% 8,928,574 $694.7M
Baker Bros. Advisors LP 3.96% Add +30.2% 8,657,242 $673.6M
Avoro Capital Advisors LLC 5.72% Add +17.7% 7,474,747 $581.6M
Vanguard Group Inc. 0.01% Add +15.6% 6,267,644 $487.7M
T. Rowe Price Associates Inc. 0.05% Add +20.8% 6,159,335 $479.3M
BVF Inc. 14.41% No change 5,502,710 $428.2M
BlackRock, Inc. 0.01% Add +14.6% 5,004,095 $389.4M
Atlas Venture Life Science Advisors, LLC 41.91% Reduce -4.8% 4,659,874 $362.6M
Wellington Management Group LLP 0.06% Reduce -15.1% 4,412,933 $343.4M
Siren, L.L.C. 7.63% Reduce -4.1% 3,286,830 $255.7M
State Street Corp. 0.01% Add +9.4% 2,209,837 $171.9M
Capital Research Global Investors 0.02% Add +23.7% 1,560,791 $121.4M
Geode Capital Management, LLC 0.01% Add +11.0% 1,417,389 $110.3M
Driehaus Capital Management LLC 0.57% Add +13.9% 1,069,238 $83.2M
Alliancebernstein L.P. 0.02% Add +1852.2% 952,065 $74.1M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% Add +5.6% 912,498 $71.0M
Merck & Co., Inc. 21.75% No change 772,165 $60.1M
Federated Hermes, Inc. 0.10% Add +36.7% 763,920 $59.4M
Holocene Advisors, LP 0.12% Reduce -9.4% 761,209 $59.2M
Commodore Capital LP 3.88% No change 750,000 $58.4M
Goldman Sachs Group Inc. 0.01% Add +4.1% 740,306 $57.6M
UBS Group AG 0.01% Add +13.6% 737,032 $57.3M
Frontier Capital Management Co. LLC 0.53% Add +22.8% 635,957 $49.5M
T. Rowe Price Investment Management, Inc. 0.03% Add +3.0% 629,745 $49.0M
Eventide Asset Management, LLC 0.76% Reduce -2.8% 626,430 $48.7M
Dimensional Fund Advisors LP 0.01% Reduce -14.7% 624,027 $48.6M
Deerfield Management Company, L.P. 0.64% Reduce -1.9% 561,170 $43.7M
Octagon Capital Advisors LP 5.21% Add +48.6% 535,000 $41.6M
Charles Schwab Investment Management Inc. 0.01% Add +13.0% 497,026 $38.7M
Rock Springs Capital Management LP 1.99% Add +10.3% 496,871 $38.7M
Jennison Associates LLC 0.02% Reduce -51.7% 496,665 $38.6M
Pictet Asset Management Holding SA 0.04% Add +39.3% 483,199 $37.8M
Northern Trust Corp. 0.00% Add +6.8% 467,022 $36.3M
Braidwell LP 1.35% Add +64.2% 454,259 $35.3M
Adage Capital Partners Gp, L.L.C. 0.05% Add +80.7% 430,000 $33.5M
Two Sigma Advisers, LP 0.06% Add +0.4% 373,800 $29.1M
Alyeska Investment Group, L.P. 0.08% Reduce -39.5% 371,889 $28.9M
Franklin Resources Inc. 0.01% Add +1019.9% 354,575 $27.6M
Bank of America Corp. 0.00% Add +82.0% 338,999 $26.4M
Boxer Capital Management, LLC 5.61% Add +3.1% 329,100 $25.6M
Massachusetts Financial Services Co. 0.01% Reduce -33.5% 289,404 $22.5M
Nextech Invest Ltd. 2.10% Reduce -18.2% 278,896 $21.7M
Morgan Stanley 0.00% Reduce -27.5% 274,018 $21.3M
Two Sigma Investments, LP 0.03% Reduce -38.2% 265,532 $20.7M
RTW Investments, LP 0.19% New 240,000 $18.7M
Gilder Gagnon Howe & Co. LLC 0.20% Reduce -2.8% 239,916 $18.7M
Deer Management Co. LLC 1.75% Reduce -29.2% 230,811 $18.0M
TD Asset Management Inc 0.01% Add +5.7% 221,178 $17.2M
First Turn Management, LLC 1.84% Reduce -25.7% 206,445 $16.1M
Woodline Partners LP 0.06% Reduce -17.9% 203,585 $15.8M
Candriam S.C.A. 0.08% Add +5.2% 201,672 $15.7M
Polar Capital Holdings Plc 0.07% Reduce -49.4% 200,946 $15.6M
Bank of New York Mellon Corp 0.00% Add +26.4% 192,748 $15.0M
TimesSquare Capital Management, LLC 0.22% New 189,900 $14.8M
Point72 Asset Management 0.02% Reduce -0.4% 173,147 $13.5M
Citadel Advisors 0.01% Add +282.2% 159,865 $12.4M
Squarepoint Ops LLC 0.03% Reduce -54.6% 159,426 $12.4M
Foresite Capital Management VI LLC 3.44% No change 146,332 $11.4M
Barclays PLC 0.00% Reduce -9.4% 140,507 $10.9M
Patient Square Capital LP 2.32% Add +50.1% 139,000 $10.8M
Manufacturers Life Insurance Company, The 0.01% Add +7.4% 135,894 $10.6M
Eagle Health Investments LP 2.33% New 136,300 $10.6M
JPMorgan Chase & Co. 0.00% Reduce -31.8% 131,353 $10.2M
Logos Global Management LP 0.67% Reduce -48.0% 130,000 $10.1M
Nuveen, LLC 0.00% Add +17.2% 125,050 $9.7M
Invesco Ltd. 0.00% Add +46.3% 116,747 $9.1M
WCM Investment Management, LLC 0.02% New 105,194 $8.2M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% Reduce -2.0% 105,554 $8.2M
Monashee Investment Management LLC 4.60% New 100,000 $7.8M
Ensign Peak Advisors, Inc 0.01% Add +3.4% 95,047 $7.4M
Swiss National Bank 0.00% Add +15.4% 94,200 $7.3M
Armistice Capital, LLC 0.15% New 81,165 $6.3M
Deutsche Bank AG 0.00% Add +9.8% 79,843 $6.2M
Burkehill Global Management, LP 0.40% No change 75,000 $5.8M
Yiheng Capital Management, L.P. 2.49% Reduce -40.1% 73,440 $5.7M
Rhumbline Advisers 0.00% Reduce -2.5% 72,304 $5.6M
Perceptive Advisors LLC 0.10% Reduce -58.8% 69,935 $5.4M
Victory Capital Management Inc. 0.00% Add +114.4% 67,086 $5.2M
Wells Fargo & Company 0.00% Add +107.4% 66,489 $5.2M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.01% Add +15622.1% 64,775 $5.0M
Alps Advisors Inc. 0.03% New 64,723 $5.0M
First Trust Advisors LP 0.00% Reduce -21.4% 58,862 $4.6M
Rafferty Asset Management, LLC 0.02% Reduce -14.1% 58,653 $4.6M
Neuberger Berman Group LLC 0.00% New 58,482 $4.6M
Informed Momentum Co LLC 0.49% Reduce -2.0% 56,455 $4.4M
Nicholas Investment Partners, LP 0.36% Add +6.0% 55,788 $4.3M
Verition Fund Management LLC 0.02% Add +72.6% 54,319 $4.2M
Schroder Investment Management Group 0.00% Reduce -14.6% 52,671 $4.1M
Comerica Bank 0.02% Reduce -3.1% 49,812 $3.9M
Russell Investments Group, Ltd. 0.00% Add +142.1% 45,977 $3.6M
California State Teachers Retirement System 0.00% Add +12.4% 45,742 $3.6M
Legal & General Group Plc 0.00% Reduce -0.2% 43,428 $3.4M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +51.5% 40,777 $3.2M
Dark Forest Capital Management LP 0.14% Add +26.3% 39,207 $3.1M
Moody Aldrich Partners LLC 0.56% Add +33.3% 38,535 $3.0M
Marshall Wace, LLP 0.00% Reduce -89.4% 38,022 $3.0M
Y-Intercept (Hong Kong) Ltd 0.06% New 36,429 $2.8M
Silverarc Capital Management, LLC 0.39% New 34,589 $2.7M
State of New Jersey Common Pension Fund D 0.01% New 33,538 $2.6M
Sio Capital Management, LLC 0.42% New 32,235 $2.5M
MetLife Investment Management, LLC 0.01% Add +6.4% 31,394 $2.4M
Nan Fung Group Holdings Ltd 2.15% No change 30,875 $2.4M
Harbor Capital Advisors, Inc. 0.18% Add +2.2% 30,573 $2.4M
Seven Grand Managers, LLC 0.18% New 30,000 $2.3M
Voya Investment Management LLC 0.00% Reduce -20.6% 28,940 $2.3M
Erste Asset Management GmbH 0.02% No change 27,000 $2.2M
Virtu Financial LLC 0.08% New 27,283 $2.1M
State of Wisconsin Investment Board 0.00% Reduce -4.5% 26,513 $2.1M
New York State Common Retirement Fund 0.00% Add +4.9% 25,596 $2.0M
Rockefeller Capital Management L.P. 0.00% Add +21538.1% 25,533 $2.0M
Trexquant Investment LP 0.02% Reduce -66.2% 24,680 $1.9M
China Universal Asset Management Co., Ltd. 0.15% Add +8.8% 24,524 $1.9M
XTX Topco Ltd 0.05% New 24,143 $1.9M
SG Americas Securities, LLC 0.00% Add +169.1% 22,693 $1.8M
Profund Advisors LLC 0.05% Add +48.1% 22,240 $1.7M
Intech Investment Management LLC 0.01% Add +46.2% 21,514 $1.7M
Janus Henderson Group PLC 0.00% Add +15.0% 21,058 $1.6M
Man Group plc 0.00% New 20,026 $1.6M
Baron Capital (BAMCO) 0.00% Add +185.7% 20,000 $1.6M
AJU IB Investment Co., Ltd. 6.71% Reduce -95.7% 19,648 $1.5M
Walleye Capital LLC 0.01% New 19,181 $1.5M
Fred Alger Management, LLC 0.01% New 18,639 $1.5M
HRT Financial LP 0.00% New 18,173 $1.4M
Handelsbanken Fonder AB 0.00% Reduce -17.1% 18,000 $1.4M
Norges Bank 0.00% — 16,543 $1.3M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +5.3% 15,631 $1.2M
B. Metzler seel. Sohn & Co. AG 0.01% New 15,607 $1.2M
Police & Firemen's Retirement System of New Jersey 0.01% Add +7.8% 15,030 $1.2M
Maven Securities LTD 0.15% New 15,000 $1.2M
Creative Planning 0.00% Add +173.9% 13,769 $1.1M
Susquehanna Portfolio Strategies, LLC 0.02% No change 13,768 $1.1M
ProShare Advisors LLC 0.00% Add +20.8% 13,489 $1.0M
Arizona State Retirement System 0.01% Add +6.9% 13,284 $1.0M
Sei Investments Co. 0.00% Reduce -13.1% 13,256 $1.0M
Teachers Retirement System of the State of Kentucky 0.01% Reduce -27.3% 13,026 $1.0M
Knights of Columbus Asset Advisors LLC 0.06% Reduce -31.8% 12,890 $1.0M
State Board of Administration of Florida Retirement System 0.00% Add +3.4% 12,655 $985K
Kennedy Capital Management LLC 0.02% Add +32.1% 12,523 $974K
Campbell & CO Investment Adviser LLC 0.04% Add +152.3% 11,534 $897K
DekaBank Deutsche Girozentrale 0.00% No change 23,562 $878K
Millennium Management 0.00% Reduce -88.2% 11,243 $875K
Clough Capital Partners L P 0.08% New 10,925 $850K
Proficio Capital Partners LLC 0.06% Add +54.9% 10,845 $844K
Citigroup Inc. 0.00% Add +52.1% 10,507 $818K
Guggenheim Capital LLC 0.01% New 10,307 $802K
KLP Kapitalforvaltning As 0.00% Add +13.3% 10,200 $794K
Legato Capital Management LLC 0.06% Add +40.6% 9,534 $742K
Odyssean, LLC 0.52% — 9,347 $727K
AQR Capital Management 0.00% Add +8.3% 9,339 $727K
Aigen Investment Management, LP 0.16% Reduce -23.4% 9,098 $708K
BNP Paribas Financial Markets 0.00% Reduce -17.4% 8,798 $685K
HSBC Holdings PLC 0.00% Reduce -26.1% 7,619 $597K
Vident Advisory, LLC 0.01% Add +6.5% 7,581 $590K
Scientech Research LLC 0.36% New 7,379 $574K
HighVista Strategies LLC 0.14% Reduce -56.5% 6,835 $532K
Keudell/Morrison Wealth Management 0.11% — 6,600 $514K
Glenmede Trust Co. NA 0.00% — 6,544 $509K
Cambridge Investment Research Advisors, Inc. 0.00% Reduce -28.4% 6,498 $506K
PSP Research LLC 0.43% — 6,348 $494K
Vestmark Advisory Solutions, Inc. 0.01% New 6,204 $483K
AlphaQuest LLC 0.03% Reduce -1.6% 5,984 $466K
Susquehanna International Group, LLP 0.00% Reduce -45.1% 5,900 $459K
Teacher Retirement System of Texas 0.00% Reduce -43.4% 5,837 $454K
Abel Hall, LLC 0.11% New 5,836 $454K
LBP Am SA 0.01% New 5,667 $441K
Allianz Asset Management GmbH 0.00% New 5,500 $428K
Envestnet Asset Management Inc. 0.00% New 5,113 $398K
AlphaCentric Advisors LLC 0.39% — 5,035 $392K
Edgestream Partners, L.P. 0.01% New 4,963 $386K
Advisors Asset Management, Inc. 0.01% Reduce -0.0% 4,941 $384K
Public Employees Retirement Association of Colorado 0.00% No change 4,672 $364K
Ameritas Investment Partners, Inc. 0.01% Add +10.7% 4,663 $363K
Xponance LLC 0.00% Add +13.1% 4,505 $351K
CANADA LIFE ASSURANCE Co 0.00% Reduce -62.5% 3,931 $306K
STRS Ohio 0.00% New 3,900 $303K
Cibc World Markets Corp. 0.00% — 3,732 $290K
Vanguard Personalized Indexing Management, LLC 0.00% New 3,646 $284K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +26.5% 3,496 $272K
Mackenzie Financial Corp. 0.00% New 3,464 $270K
Ameriprise Financial Inc. 0.00% Reduce -85.8% 3,426 $267K
Prudential Financial Inc. 0.00% Reduce -47.9% 3,410 $265K
Cetera Investment Advisers 0.00% New 3,350 $261K
Principal Financial Group Inc. 0.00% Reduce -13.6% 3,333 $259K
Belvedere Trading LLC 0.05% New 3,282 $255K
Private Advisor Group, LLC 0.00% New 3,239 $252K
Virtus Investment Advisers, LLC 0.06% Add +23.3% 2,966 $231K
CIBC Asset Management Inc 0.00% New 2,939 $229K
Mosaic Financial Group, LLC 0.15% New 2,890 $225K
Orion Porfolio Solutions, LLC 0.00% New 2,868 $223K
American Century Companies Inc. 0.00% New 2,819 $219K
Drive Wealth Management, LLC 0.04% New 2,797 $218K
Aquatic Capital Management LLC 0.01% Reduce -82.5% 2,690 $209K
Perbak Capital Partners LLP 0.06% Reduce -64.8% 2,638 $205K
Caitong International Asset Management Co., Ltd 0.05% New 2,542 $198K
Royal Bank of Canada 0.00% Reduce -99.0% 2,263 $176K
US Bancorp \de 0.00% Add +20.1% 2,240 $174K
Amalgamated Bank 0.00% Add +9.0% 1,772 $138K
KBC Group NV 0.00% No change 1,716 $134K
Los Angeles Capital Management LLC 0.00% New 1,968 $121K
GF Fund Management Co. LTD. 0.00% Reduce -8.1% 1,413 $110K
Osaic Holdings, Inc. 0.00% Add +5.4% 1,381 $107K
Acadian Asset Management LLC 0.00% New 1,382 $107K
Tower Research Capital LLC (TRC) 0.00% Reduce -42.5% 1,262 $98K
Larson Financial Group LLC 0.00% Add +36.9% 1,064 $83K
Bessemer Group Inc. 0.00% Add +1.1% 950 $74K
MAI Capital Management 0.00% No change 924 $72K
PNC Financial Services Group, Inc. 0.00% Add +4.3% 822 $64K
Smartleaf Asset Management LLC 0.00% Add +382.0% 535 $42K
Nisa Investment Advisors, LLC 0.00% No change 499 $39K
Sterling Capital Management LLC 0.00% Add +204.1% 371 $29K
GAMMA Investing LLC 0.00% Add +74.3% 298 $23K
Cwm, LLC 0.00% Add +15.1% 298 $23K
SBI Securities Co., Ltd. 0.00% No change 286 $22K
EverSource Wealth Advisors, LLC 0.00% Reduce -2.5% 277 $22K
Kestra Advisory Services, LLC 0.00% New 276 $21K
Truvestments Capital LLC 0.00% No change 274 $21K
Optiver Holding B.V. 0.00% Reduce -26.7% 236 $18K
Jones Financial Companies LLLP 0.00% Add +9.4% 221 $17K
Daiwa Securities Group Inc. 0.00% No change 215 $17K
IFP Advisors, Inc 0.00% No change 185 $14K
Kemnay Advisory Services Inc. 0.00% New 183 $14K
Whittier Trust Co. 0.00% No change 183 $13K
Farther Finance Advisors, LLC 0.00% Add +96.4% 165 $13K
Inspire Investing, LLC 0.00% New 165 $13K
Accent Capital Management, LLC 0.01% New 150 $12K
Signaturefd, LLC 0.00% No change 140 $11K
Cygnus Capital Advisors, LLC 0.01% — 121 $9K
Rothschild Investment LLC 0.00% Add +4.2% 99 $8K
Root Financial Partners, LLC 0.00% Add +110.0% 84 $7K
Eastern Bank 0.00% New 74 $6K
Parkside Financial Bank & Trust 0.00% No change 68 $5K
Bare Financial Services, Inc 0.00% Add +138.1% 50 $4K
Quantbot Technologies LP 0.00% New 48 $4K
Allworth Financial LP 0.00% No change 44 $3K
Arax Advisory Partners 0.00% Reduce -89.7% 37 $3K
SJS Investment Consulting Inc. 0.00% Add +3300.0% 34 $3K
Manchester Capital Management LLC 0.00% New 31 $2K
Northwestern Mutual Wealth Management Co. 0.00% New 28 $2K
Torren Management, LLC 0.00% — 24 $2K
Fortitude Family Office, LLC 0.00% Add +16.7% 21 $2K
Parallel Advisors, LLC 0.00% No change 20 $2K
Keating Financial Advisory Services, Inc. 0.00% — 19 $1K
JFS Wealth Advisors, LLC 0.00% Add +1500.0% 16 $1K
Global Retirement Partners, LLC 0.00% New 15 $1K
Rachor Investment Advisory Services, LLC 0.00% — 14 $1K
TD Private Client Wealth LLC 0.00% No change 12 $934
Basecamp Wealth Advisors LLC 0.00% — 9 $700
Bell Investment Advisors, Inc 0.00% New 6 $467
DiNuzzo Private Wealth, Inc. 0.00% Add +200.0% 6 $467
Assetmark, Inc. 0.00% No change 6 $467
Rialto Wealth Management, LLC 0.00% Add +200.0% 3 $234
HFM Investment Advisors, LLC 0.00% Add +100.0% 2 $156
Bay Harbor Wealth Management, LLC 0.00% New 1 $77
Dunhill Financial, LLC 0.00% New 1 $62
Covestor Ltd 0.00% No change 4 $0

"% of holder's portfolio" is KYMR's weight in each manager's 13F, not the share of Kymera Therapeutics Inc. the manager owns.