| Vida Ventures Advisors, LLC | 62.43% | New | 4,523,924 | $112.4M |
| Northpond Ventures, LLC | 78.80% | New | 3,255,426 | $80.9M |
| Bain Capital Life Sciences Investors, LLC | 6.32% | New | 3,163,868 | $78.6M |
| RTW Investments, LP | 0.68% | New | 1,852,711 | $46.0M |
| Deerfield Management Company, L.P. | 0.70% | New | 1,462,337 | $36.3M |
| Jennison Associates LLC | 0.02% | New | 1,398,659 | $34.7M |
| T. Rowe Price Associates Inc. | 0.00% | New | 929,634 | $23.1M |
| Insight Holdings Group, LLC | 0.63% | New | 912,915 | $22.7M |
| Commodore Capital LP | 1.52% | New | 912,189 | $22.7M |
| JPMorgan Chase & Co. | 0.00% | New | 844,465 | $21.0M |
| BlackRock Inc. | 0.00% | New | 749,966 | $18.6M |
| Novo Holdings A/S | 1.20% | New | 700,000 | $17.4M |
| Millennium Management | 0.02% | New | 695,094 | $17.3M |
| Janus Henderson Group PLC | 0.01% | New | 606,500 | $15.0M |
| Wellington Management Group LLP | 0.00% | New | 601,436 | $14.9M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | New | 575,000 | $14.3M |
| Citadel Advisors | 0.01% | New | 523,743 | $13.0M |
| Logos Global Management LP | 1.31% | New | 500,000 | $12.4M |
| Alliancebernstein L.P. | 0.00% | New | 475,827 | $11.8M |
| Avoro Capital Advisors LLC | 0.14% | New | 475,000 | $11.8M |
| Franklin Resources Inc. | 0.00% | New | 460,561 | $11.4M |
| EcoR1 Capital, LLC | 0.28% | New | 450,000 | $11.2M |
| Cormorant Asset Management, LP | 0.48% | New | 440,000 | $10.9M |
| Woodline Partners LP | 0.09% | New | 392,928 | $9.8M |
| Vanguard Group Inc. | 0.00% | New | 264,215 | $6.6M |
| Avidity Partners Management LP | 0.18% | New | 202,333 | $5.0M |
| Artal Group S.A. | 0.13% | New | 200,000 | $5.0M |
| Rock Springs Capital Management LP | 0.11% | New | 178,963 | $4.4M |
| Geode Capital Management, LLC | 0.00% | New | 172,236 | $4.3M |
| Cutter Capital Management, LP | 1.59% | New | 166,514 | $4.1M |
| Marshall Wace, LLP | 0.01% | New | 155,755 | $3.9M |
| Great Point Partners LLC | 0.58% | New | 150,000 | $3.7M |
| Casdin Capital, LLC | 0.28% | New | 150,000 | $3.7M |
| Perceptive Advisors LLC | 0.07% | New | 150,000 | $3.7M |
| Walleye Capital LLC | 0.04% | New | 150,000 | $3.7M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 105,900 | $2.6M |
| LMR Partners LLP | 0.09% | New | 104,814 | $2.6M |
| Blackstone Inc. | 0.01% | New | 100,000 | $2.5M |
| Pictet Asset Management Holding SA | 0.00% | New | 100,000 | $2.5M |
| Squarepoint Ops LLC | 0.01% | New | 88,423 | $2.2M |
| Charles Schwab Investment Management Inc. | 0.00% | New | 84,880 | $2.1M |
| Invesco Ltd. | 0.00% | New | 75,865 | $1.9M |
| ArrowMark Colorado Holdings LLC | 0.02% | New | 70,000 | $1.7M |
| Qube Research & Technologies Ltd | 0.00% | New | 69,237 | $1.7M |
| Alyeska Investment Group, L.P. | 0.01% | New | 65,000 | $1.6M |
| Point72 (DIFC) Ltd | 0.12% | — | 60,800 | $1.5M |
| Citigroup Inc. | 0.00% | New | 59,666 | $1.5M |
| State Street Corp. | 0.00% | New | 50,400 | $1.3M |
| Paradigm Biocapital Advisors LP | 0.04% | New | 50,000 | $1.2M |
| Hudson Bay Capital Management LP | 0.01% | New | 50,000 | $1.2M |
| Barclays PLC | 0.00% | New | 43,094 | $1.1M |
| Stempoint Capital LP | 0.27% | New | 41,000 | $1.0M |
| Ghisallo Capital Management LLC | 0.13% | New | 40,000 | $994K |
| Polar Asset Management Partners Inc. | 0.04% | New | 40,000 | $994K |
| Norges Bank | 0.00% | New | 40,000 | $994K |
| Morgan Stanley | 0.00% | New | 39,931 | $992K |
| Laurion Capital Management LP | 0.03% | New | 37,500 | $932K |
| Jane Street Group, LLC | 0.00% | New | 37,041 | $920K |
| Ameriprise Financial Inc. | 0.00% | New | 36,583 | $909K |
| Northern Trust Corp. | 0.00% | New | 28,793 | $715K |
| Manufacturers Life Insurance Company, The | 0.00% | New | 28,494 | $708K |
| Discovery Capital Management, LLC / CT | 0.09% | New | 25,000 | $621K |
| UBS Group AG | 0.00% | New | 24,898 | $618K |
| Point72 Asset Management | 0.00% | New | 20,900 | $519K |
| Two Sigma Investments, LP | 0.00% | New | 20,842 | $518K |
| Davidson Kempner Capital Management LP | 0.01% | New | 20,000 | $495K |
| Skandinaviska Enskilda Banken AB (publ) | 0.00% | New | 16,810 | $418K |
| Balyasny Asset Management L.P. | 0.00% | New | 16,721 | $415K |
| Caxton Corp. | 2.24% | New | 15,846 | $394K |
| Bank of America Corp. | 0.00% | New | 13,016 | $323K |
| Teachers Retirement System of the State of Kentucky | 0.00% | New | 12,614 | $313K |
| Wells Fargo & Company | 0.00% | New | 11,906 | $296K |
| Prudential Financial Inc. | 0.00% | New | 11,500 | $286K |
| Brevan Howard Capital Management LP | 0.03% | New | 11,435 | $284K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.07% | New | 10,133 | $252K |
| Greenland Capital Management LP | 0.04% | New | 10,000 | $248K |
| Sofinnova Investments, Inc. | 0.01% | New | 10,000 | $248K |
| Legal & General Group Plc | 0.00% | New | 9,585 | $238K |
| Diametric Capital, LP | 0.13% | New | 9,300 | $231K |
| Tudor Investment Corporation | 0.00% | New | 8,492 | $211K |
| DekaBank Deutsche Girozentrale | 0.00% | New | 7,500 | $181K |
| Sectoral Asset Management Inc. | 0.07% | New | 7,000 | $174K |
| Cubist Systematic Strategies, LLC | 0.00% | New | 2,775 | $69K |
| Osaic Holdings, Inc. | 0.00% | New | 2,000 | $50K |
| Tower Research Capital LLC (TRC) | 0.00% | New | 766 | $19K |
| New York State Common Retirement Fund | 0.00% | New | 183 | $5K |
| Comerica Bank | 0.00% | New | 63 | $2K |
| Washington Trust Advisors, Inc. | 0.00% | New | 60 | $1K |
| Macquarie Group Ltd. | 0.00% | New | 950 | $24 |
| Royal Bank of Canada | 0.00% | New | 4 | $0 |