Kyverna TherapeuticsKYTX
13F holders, Q4 2025 (December 31)99holders +24
33new positions
9sold out
5famous investors
$9.40avg. 13F price*
At the end of Q4 2025, 99 institutions reported holding Kyverna Therapeutics Inc. (KYTX) in their 13F filings, up 24 from Q3 2025. 33 opened new positions and 9 sold out. The largest holders were GordonMD Global Investments LP ($41.3M), Gilead Sciences, Inc. ($38.8M) and Bain Capital Life Sciences Investors, LLC ($29.2M). 5 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Kyverna Therapeutics Inc.
- CUSIP
- 501976104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 33 | $97.2M |
| Exits | 9 | $8.0M |
All 13F filers, Q3 2025 → Q4 2025: 13,707,327 shares bought and 2,187,223 shares sold, net +11,520,104 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 99 holders
| GordonMD Global Investments LP | 29.60% | — | 4,391,818 | $41.3M |
| Gilead Sciences, Inc. | 2.00% | No change | 4,126,119 | $38.8M |
| Bain Capital Life Sciences Investors, LLC | 2.24% | Reduce -7.7% | 3,110,000 | $29.2M |
| Deerfield Management Company, L.P. | 0.27% | New | 2,000,000 | $18.8M |
| Vanguard Group Inc. | 0.00% | Add +34.7% | 1,781,257 | $16.7M |
| T. Rowe Price Associates Inc. | 0.00% | Add +16.6% | 1,762,617 | $16.6M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | New | 1,666,666 | $15.7M |
| AIGH Capital Management LLC | 4.17% | New | 1,500,000 | $14.1M |
| Morgan Stanley | 0.00% | Add +475.5% | 1,002,495 | $9.4M |
| Insight Holdings Group, LLC | 0.70% | No change | 989,054 | $9.3M |
| Balyasny Asset Management L.P. | 0.02% | New | 980,869 | $9.2M |
| Woodline Partners LP | 0.03% | Add +235.1% | 845,143 | $7.9M |
| Propel Bio Management, LLC | 5.35% | New | 666,666 | $6.3M |
| MBB Public Markets I LLC | 0.60% | No change | 614,477 | $5.8M |
| Alyeska Investment Group, L.P. | 0.02% | New | 600,000 | $5.6M |
| Millennium Management | 0.00% | Add +7.6% | 593,369 | $5.6M |
| BlackRock, Inc. | 0.00% | Add +13.0% | 544,539 | $5.1M |
| D. E. Shaw & Co. | 0.00% | New | 518,512 | $4.9M |
| RFG Advisory, LLC | 0.08% | New | 445,200 | $4.2M |
| Citadel Advisors | 0.00% | Add +1459.2% | 275,446 | $2.6M |
| Heights Capital Management, Inc. | 0.98% | New | 271,822 | $2.6M |
| Geode Capital Management, LLC | 0.00% | Reduce -4.3% | 266,402 | $2.5M |
| BNP Paribas Financial Markets | 0.00% | Add +641.1% | 252,151 | $2.4M |
| Susquehanna International Group, LLP | 0.00% | Add +17.8% | 238,828 | $2.2M |
| TD Asset Management Inc | 0.00% | Add +35.2% | 222,796 | $2.1M |
| Two Sigma Investments, LP | 0.00% | Add +55.0% | 205,267 | $1.9M |
| UBS Group AG | 0.00% | Add +28.4% | 202,187 | $1.9M |
| Burkehill Global Management, LP | 0.13% | New | 200,000 | $1.9M |
| Monashee Investment Management LLC | 1.08% | New | 195,000 | $1.8M |
| Simplify Asset Management Inc. | 0.03% | New | 192,339 | $1.8M |
| Peapod Lane Capital LLC | 1.47% | Reduce -42.3% | 183,820 | $1.7M |
| Jane Street Group, LLC | 0.00% | Reduce -8.4% | 182,093 | $1.7M |
| Renaissance Technologies | 0.00% | Add +8.1% | 177,899 | $1.7M |
| Bridgeway Capital Management, LLC | 0.03% | No change | 174,900 | $1.6M |
| Barclays PLC | 0.00% | Add +116.1% | 164,668 | $1.5M |
| Maven Securities LTD | 0.17% | New | 146,400 | $1.4M |
| Squarepoint Ops LLC | 0.00% | New | 138,868 | $1.3M |
| Marshall Wace, LLP | 0.00% | New | 135,600 | $1.3M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +29.6% | 134,530 | $1.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +209.6% | 133,530 | $1.3M |
| Stifel Financial Corp. | 0.00% | Add +224.0% | 125,790 | $1.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -0.1% | 125,426 | $1.2M |
| 683 Capital Management, LLC | 0.09% | New | 114,900 | $1.1M |
| Kera Capital Partners, Inc. | 0.13% | Reduce -68.6% | 132,603 | $1.1M |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -26.5% | 108,534 | $1.0M |
| State Street Corp. | 0.00% | No change | 91,300 | $858K |
| Hudson Bay Capital Management LP | 0.01% | New | 88,553 | $832K |
| Jump Financial, LLC | 0.01% | New | 80,299 | $755K |
| Dimensional Fund Advisors LP | 0.00% | New | 78,413 | $737K |
| Wells Fargo & Company | 0.00% | Add +310.0% | 74,949 | $705K |
| Voya Investment Management LLC | 0.00% | New | 68,140 | $641K |
| Qube Research & Technologies Ltd | 0.00% | Add +73.4% | 63,616 | $598K |
| ADAR1 Capital Management, LLC | 0.04% | New | 57,428 | $540K |
| Quadrature Capital Ltd | 0.01% | New | 57,369 | $539K |
| Nano Cap New Millennium Growth Fund L P | 0.43% | — | 53,500 | $503K |
| Northern Trust Corp. | 0.00% | Reduce -0.2% | 51,572 | $485K |
| Two Sigma Advisers, LP | 0.00% | Reduce -39.2% | 49,400 | $464K |
| American Century Companies Inc. | 0.00% | Add +44.0% | 46,367 | $436K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 34,800 | $327K |
| Point72 Asset Management | 0.00% | Add +18.4% | 32,184 | $303K |
| Jefferies Financial Group Inc. | 0.00% | Add +96.3% | 32,001 | $301K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 28,872 | $271K |
| Bank of America Corp. | 0.00% | Reduce -55.8% | 28,709 | $270K |
| Act Capital Management, LLC | 0.19% | — | 25,100 | $236K |
| Raymond James Financial Inc. | 0.00% | New | 25,082 | $236K |
| XTX Topco Ltd | 0.01% | Reduce -52.6% | 23,282 | $219K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 7,500 | $197K |
| Federated Hermes, Inc. | 0.00% | Add +36.6% | 20,705 | $195K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +0.8% | 19,048 | $179K |
| Caxton Corp. | 4.12% | Reduce -18.3% | 18,773 | $176K |
| Cambria Investment Management, L.P. | 0.01% | New | 17,935 | $169K |
| AlphaQuest LLC | 0.01% | New | 16,343 | $154K |
| Ethic Inc. | 0.00% | Reduce -17.9% | 12,609 | $119K |
| Phoenix Wealth Advisors | 0.04% | Add +17.1% | 12,300 | $116K |
| Citigroup Inc. | 0.00% | Add +270.5% | 12,297 | $116K |
| EntryPoint Capital, LLC | 0.04% | New | 10,048 | $94K |
| Capital Advisors Inc. | 0.00% | No change | 10,000 | $94K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -5.8% | 7,137 | $67K |
| FMR LLC | 0.00% | Reduce -11.9% | 6,976 | $66K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -18.6% | 5,073 | $48K |
| JPMorgan Chase & Co. | 0.00% | Reduce -36.0% | 4,274 | $40K |
| Deutsche Bank AG | 0.00% | No change | 3,917 | $37K |
| Osaic Holdings, Inc. | 0.00% | Add +29.0% | 3,225 | $30K |
| Royal Bank of Canada | 0.00% | Add +61.5% | 3,264 | $30K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +27.3% | 2,128 | $20K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 1,668 | $16K |
| Russell Investments Group, Ltd. | 0.00% | No change | 1,313 | $12K |
| Vermillion & White Wealth Management Group, LLC | 0.01% | New | 1,100 | $10K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -4.2% | 860 | $8K |
| National Bank of Canada | 0.00% | New | 400 | $4K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 301 | $3K |
| TFC Financial Management, Inc. | 0.00% | New | 300 | $3K |
| Fourth Dimension Wealth, LLC | 0.00% | No change | 250 | $2K |
| Cwm, LLC | 0.00% | Reduce -47.3% | 263 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -18.5% | 163 | $2K |
| Jones Financial Companies LLLP | 0.00% | New | 37 | $348 |
| Parallel Advisors, LLC | 0.00% | New | 26 | $244 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -83.9% | 22 | $207 |
| Arax Advisory Partners | 0.00% | No change | 11 | $103 |
"% of holder's portfolio" is KYTX's weight in each manager's 13F, not the share of Kyverna Therapeutics Inc. the manager owns.