Lenz TherapeuticsLENZ
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 161 institutions reported holding Lenz Therapeutics Inc. (LENZ) in their 13F filings, down 5 from Q3 2025. 47 opened new positions and 55 sold out. The largest holders were Ra Capital Management, L.P. ($66.9M), FMR LLC ($59.2M) and Alpha Wave Global, LP ($57.8M). 2 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Lenz Therapeutics Inc.
- CUSIP
- 52635N103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 47 | $73.1M |
| Exits | 55 | $264.3M |
All 13F filers, Q3 2025 → Q4 2025: 12,707,242 shares bought and 7,254,455 shares sold, net +5,452,787 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 161 holders
| Ra Capital Management, L.P. | 0.69% | No change | 4,178,823 | $66.9M |
| FMR LLC | 0.00% | Add +4140.7% | 3,702,718 | $59.2M |
| Alpha Wave Global, LP | 7.08% | No change | 3,612,211 | $57.8M |
| Versant Venture Management, LLC | 28.14% | No change | 2,656,888 | $42.5M |
| BlackRock, Inc. | 0.00% | Add +14.9% | 1,692,006 | $27.1M |
| UBS Group AG | 0.01% | Add +30.8% | 1,571,738 | $25.1M |
| Vanguard Group Inc. | 0.00% | Reduce -0.7% | 1,321,202 | $21.1M |
| Franklin Resources Inc. | 0.00% | Add +86.7% | 1,096,334 | $17.5M |
| T. Rowe Price Associates Inc. | 0.00% | Add +307.6% | 1,023,542 | $16.4M |
| 72 Investment Holdings, LLC | 32.20% | No change | 1,017,751 | $16.3M |
| Tang Capital Management LLC | 0.68% | Reduce -3.6% | 865,169 | $13.8M |
| Intrinsic Edge Capital Management LLC | 1.77% | New | 569,705 | $9.1M |
| Millennium Management | 0.01% | New | 539,348 | $8.6M |
| State Street Corp. | 0.00% | Add +22.2% | 510,749 | $8.2M |
| C WorldWide Group Holding A/S | 0.14% | New | 500,000 | $8.0M |
| Squarepoint Ops LLC | 0.02% | Add +447.8% | 491,898 | $7.9M |
| Aberdeen Group plc | 0.01% | Add +274.4% | 489,432 | $7.8M |
| Alyeska Investment Group, L.P. | 0.02% | Add +91.4% | 463,495 | $7.4M |
| Geode Capital Management, LLC | 0.00% | Add +1.4% | 461,075 | $7.4M |
| Granahan Investment Management, LLC | 0.30% | Add +125.2% | 431,100 | $6.9M |
| Nomura Asset Management International Inc. | 0.01% | — | 398,566 | $6.4M |
| Candriam S.C.A. | 0.03% | Add +63.8% | 374,932 | $6.0M |
| Primecap Management Co. | 0.00% | New | 372,200 | $6.0M |
| Two Sigma Investments, LP | 0.01% | Add +387.6% | 293,446 | $4.7M |
| Vestal Point Capital, LP | 0.16% | New | 275,000 | $4.4M |
| Jacobs Levy Equity Management, Inc. | 0.02% | New | 270,919 | $4.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +524.9% | 257,942 | $4.1M |
| Rock Springs Capital Management LP | 0.21% | Add +9.0% | 257,460 | $4.1M |
| Discovery Capital Management, LLC / CT | 0.21% | New | 241,300 | $3.9M |
| Morgan Stanley | 0.00% | Reduce -21.2% | 233,382 | $3.7M |
| Plustick Management LLC | 1.42% | No change | 200,000 | $3.2M |
| Skandinaviska Enskilda Banken AB (publ) | 0.01% | No change | 185,642 | $3.0M |
| Sovran Advisors, LLC | 0.25% | Add +49.8% | 160,134 | $2.9M |
| Silvercrest Asset Management Group LLC | 0.02% | New | 174,692 | $2.8M |
| Trexquant Investment LP | 0.02% | New | 173,183 | $2.8M |
| HRT Financial LP | 0.01% | Add +484.4% | 171,283 | $2.7M |
| Prelude Capital Management, LLC | 0.20% | New | 170,224 | $2.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +5.3% | 169,122 | $2.7M |
| Northern Trust Corp. | 0.00% | Reduce -2.0% | 161,911 | $2.6M |
| Blue Owl Capital Holdings LP | 0.75% | New | 150,000 | $2.4M |
| AWM Investment Company, Inc. | 0.23% | New | 150,000 | $2.4M |
| Ameriprise Financial Inc. | 0.00% | Add +145.9% | 136,896 | $2.2M |
| Scoggin Management LP | 0.76% | Reduce -44.4% | 125,000 | $2.0M |
| Bank of America Corp. | 0.00% | Reduce -67.2% | 114,688 | $1.8M |
| Dimensional Fund Advisors LP | 0.00% | Add +176.6% | 113,094 | $1.8M |
| Woodline Partners LP | 0.01% | New | 100,000 | $1.6M |
| Nomura Asset Management Co. Ltd. | 0.00% | Add +121.1% | 96,780 | $1.5M |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Reduce -0.1% | 83,243 | $1.4M |
| XTX Topco Ltd | 0.04% | New | 85,782 | $1.4M |
| Citadel Advisors | 0.00% | Reduce -79.8% | 80,574 | $1.3M |
| VARCOV Co. | 0.50% | — | 78,831 | $1.3M |
| Two Sigma Advisers, LP | 0.00% | Add +905.9% | 77,426 | $1.2M |
| Ensign Peak Advisors, Inc | 0.00% | No change | 77,275 | $1.2M |
| Algert Global LLC | 0.02% | New | 76,025 | $1.2M |
| Barclays PLC | 0.00% | Add +51.5% | 72,432 | $1.2M |
| Susquehanna International Group, LLP | 0.00% | Add +34.0% | 67,722 | $1.1M |
| Debussy Capital Management LP | 0.14% | Add +23.8% | 64,052 | $1.0M |
| Federated Hermes, Inc. | 0.00% | New | 62,636 | $1.0M |
| Propel Bio Management, LLC | 0.81% | New | 59,085 | $945K |
| Wellington Management Group LLP | 0.00% | Reduce -11.3% | 54,402 | $870K |
| Knott David M Jr | 0.40% | Reduce -34.5% | 53,732 | $860K |
| Perceptive Advisors LLC | 0.01% | New | 50,000 | $800K |
| Rockefeller Capital Management L.P. | 0.00% | Add +167.1% | 48,071 | $769K |
| Jane Street Group, LLC | 0.00% | Add +378.7% | 46,847 | $750K |
| Verition Fund Management LLC | 0.00% | New | 46,268 | $740K |
| Qube Research & Technologies Ltd | 0.00% | New | 44,290 | $709K |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.7% | 44,055 | $705K |
| Royal Bank of Canada | 0.00% | Reduce -10.6% | 43,172 | $691K |
| Aquatic Capital Management LLC | 0.02% | New | 42,729 | $684K |
| Sectoral Asset Management Inc. | 0.55% | New | 42,500 | $680K |
| Jump Financial, LLC | 0.01% | New | 40,851 | $654K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | New | 40,615 | $650K |
| Nuveen, LLC | 0.00% | Reduce -86.0% | 39,905 | $638K |
| Virtus Investment Advisers, LLC | 0.16% | Add +879.3% | 37,674 | $603K |
| Marshall Wace, LLP | 0.00% | New | 35,252 | $564K |
| State of Wisconsin Investment Board | 0.00% | Add +33.7% | 32,235 | $516K |
| Engineers Gate Manager LP | 0.01% | New | 31,058 | $497K |
| Kestra Private Wealth Services, LLC | 0.01% | No change | 27,304 | $437K |
| TD Asset Management Inc | 0.00% | Reduce -14.1% | 26,978 | $432K |
| Harbor Capital Advisors, Inc. | 0.03% | Add +63.8% | 23,921 | $383K |
| ExodusPoint Capital Management, LP | 0.00% | New | 23,147 | $370K |
| Freestone Grove Partners LP | 0.00% | New | 22,971 | $368K |
| Wells Fargo & Company | 0.00% | Add +119.3% | 22,916 | $367K |
| Swiss National Bank | 0.00% | No change | 21,800 | $349K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -0.8% | 20,816 | $335K |
| Rhumbline Advisers | 0.00% | Reduce -19.1% | 20,250 | $324K |
| Axq Capital, LP | 0.07% | Add +289.1% | 19,839 | $317K |
| AlphaQuest LLC | 0.02% | Add +36.3% | 19,613 | $314K |
| DNB Asset Management AS | 0.00% | New | 19,163 | $307K |
| State of Alaska, Department of Revenue | 0.00% | New | 19,159 | $306K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +61.2% | 18,851 | $302K |
| Simplify Asset Management Inc. | 0.00% | New | 17,481 | $280K |
| Kelleher Financial Advisors | 0.06% | No change | 17,023 | $272K |
| Quantbot Technologies LP | 0.01% | New | 16,879 | $270K |
| Gsa Capital Partners LLP | 0.02% | Add +39.0% | 16,455 | $263K |
| Marex Group Ltd | 0.00% | New | 16,000 | $256K |
| Fox Run Management, L.L.C. | 0.04% | New | 15,739 | $252K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -89.3% | 15,461 | $247K |
| Brevan Howard Capital Management LP | 0.01% | New | 15,408 | $247K |
| Rinkey Investments | 0.06% | No change | 15,186 | $243K |
"% of holder's portfolio" is LENZ's weight in each manager's 13F, not the share of Lenz Therapeutics Inc. the manager owns.