Lexeo TherapeuticsLXEO
13F holders, Q3 2025 (September 30)109holders +19
26new positions
7sold out
7famous investors
$6.64avg. 13F price*
At the end of Q3 2025, 109 institutions reported holding Lexeo Therapeutics Inc. (LXEO) in their 13F filings, up 19 from Q2 2025. 26 opened new positions and 7 sold out. The largest holders were Janus Henderson Group PLC ($40.5M), Frazier Life Sciences Management, L.P. ($29.4M) and Balyasny Asset Management L.P. ($26.0M). 7 famous investors held it, including Daniel Sundheim (0.1% of D1 Capital Partners's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Lexeo Therapeutics Inc.
- CUSIP
- 52886X107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 26 | $14.8M |
| Exits | 7 | $8.5M |
All 13F filers, Q2 2025 → Q3 2025: 9,905,520 shares bought and 2,825,620 shares sold, net +7,079,900 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 109 holders
| Janus Henderson Group PLC | 0.02% | Add +65.7% | 6,105,527 | $40.5M |
| Frazier Life Sciences Management, L.P. | 0.88% | No change | 4,424,725 | $29.4M |
| Balyasny Asset Management L.P. | 0.05% | Reduce -2.4% | 3,913,788 | $26.0M |
| Affinity Asset Advisors, LLC | 2.47% | Add +7.8% | 3,870,527 | $25.7M |
| Citadel Advisors | 0.02% | Add +3.1% | 3,719,043 | $24.7M |
| Vestal Point Capital, LP | 0.98% | Add +0.7% | 3,250,000 | $21.6M |
| Woodline Partners LP | 0.08% | No change | 2,572,162 | $17.1M |
| Millennium Management | 0.01% | Reduce -18.4% | 2,313,642 | $15.4M |
| Vanguard Group Inc. | 0.00% | Add +11.2% | 2,226,290 | $14.8M |
| BlackRock, Inc. | 0.00% | Add +18.8% | 2,171,092 | $14.4M |
| Point72 Asset Management | 0.03% | Add +199.7% | 1,941,849 | $12.9M |
| ADAR1 Capital Management, LLC | 1.01% | Add +955.7% | 1,531,953 | $10.2M |
| Blackstone Inc. | 0.03% | No change | 1,124,922 | $7.5M |
| D1 Capital Partners | 0.07% | No change | 978,652 | $6.5M |
| 683 Capital Management, LLC | 0.58% | New | 922,662 | $6.1M |
| Dimensional Fund Advisors LP | 0.00% | Add +1840.6% | 912,533 | $6.1M |
| Silverarc Capital Management, LLC | 0.75% | New | 778,611 | $5.2M |
| Geode Capital Management, LLC | 0.00% | Add +24.9% | 721,881 | $4.8M |
| Siren, L.L.C. | 0.16% | No change | 603,435 | $4.0M |
| Ikarian Capital, LLC | 0.76% | Add +3.2% | 567,601 | $3.8M |
| State Street Corp. | 0.00% | Add +6.2% | 544,845 | $3.6M |
| Verition Fund Management LLC | 0.02% | No change | 414,863 | $2.8M |
| DAFNA Capital Management LLC | 0.60% | Reduce -5.3% | 358,083 | $2.4M |
| AQR Capital Management | 0.00% | Add +84.4% | 347,923 | $2.3M |
| UBS Group AG | 0.00% | Reduce -8.1% | 249,909 | $1.7M |
| Northern Trust Corp. | 0.00% | Add +17.8% | 236,453 | $1.6M |
| Privium Fund Management B.V. | 0.23% | Add +7.8% | 192,356 | $1.3M |
| Boothbay Fund Management, LLC | 0.03% | Add +10.8% | 180,744 | $1.2M |
| Ameriprise Financial Inc. | 0.00% | New | 166,538 | $1.1M |
| Renaissance Technologies | 0.00% | Add +40.6% | 149,300 | $991K |
| Goldman Sachs Group Inc. | 0.00% | Add +291.6% | 142,402 | $946K |
| Perceptive Advisors LLC | 0.03% | No change | 139,835 | $929K |
| Jane Street Group, LLC | 0.00% | New | 129,472 | $860K |
| Barclays PLC | 0.00% | Reduce -3.9% | 111,579 | $741K |
| Charles Schwab Investment Management Inc. | 0.00% | Add +64.7% | 105,760 | $702K |
| Morgan Stanley | 0.00% | Add +15.7% | 98,057 | $651K |
| Two Sigma Investments, LP | 0.00% | Add +22.4% | 84,763 | $563K |
| Bank of New York Mellon Corp | 0.00% | Add +10.0% | 71,677 | $476K |
| Palumbo Wealth Management LLC | 0.13% | Add +8.8% | 61,276 | $407K |
| Bridgeway Capital Management, LLC | 0.01% | Reduce -9.4% | 48,400 | $321K |
| Virtu Financial LLC | 0.02% | New | 43,269 | $287K |
| American Century Companies Inc. | 0.00% | New | 36,154 | $240K |
| Panagora Asset Management Inc. | 0.00% | Reduce -1.3% | 34,297 | $228K |
| Pale Fire Capital SE | 0.02% | Add +21.7% | 33,650 | $223K |
| Ieq Capital, LLC | 0.00% | Add +183.4% | 33,581 | $223K |
| Nuveen, LLC | 0.00% | No change | 33,102 | $220K |
| Rhumbline Advisers | 0.00% | Reduce -0.7% | 31,764 | $211K |
| BNP Paribas Financial Markets | 0.00% | Reduce -36.6% | 30,727 | $204K |
| Alliancebernstein L.P. | 0.00% | No change | 29,370 | $195K |
| Susquehanna International Group, LLP | 0.00% | Reduce -39.7% | 28,931 | $192K |
| Bank of America Corp. | 0.00% | Add +6.1% | 28,279 | $188K |
| ExodusPoint Capital Management, LP | 0.00% | New | 27,380 | $182K |
| XTX Topco Ltd | 0.01% | New | 26,715 | $177K |
| Deutsche Bank AG | 0.00% | Add +1.7% | 24,322 | $161K |
| Cerity Partners LLC | 0.00% | Add +89.5% | 23,590 | $157K |
| Susquehanna Portfolio Strategies, LLC | 0.00% | Add +2.9% | 22,909 | $152K |
| HRT Financial LP | 0.00% | New | 21,510 | $142K |
| Soltis Investment Advisors LLC | 0.01% | No change | 20,000 | $133K |
| Wells Fargo & Company | 0.00% | Add +25.7% | 19,262 | $128K |
| Cwm, LLC | 0.00% | Add +82.2% | 18,864 | $125K |
| Brevan Howard Capital Management LP | 0.00% | New | 18,400 | $122K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | New | 14,244 | $119K |
| Caxton Corp. | 0.50% | No change | 17,332 | $115K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +10.6% | 16,595 | $110K |
| Axq Capital, LP | 0.04% | Add +19.6% | 14,921 | $99K |
| JPMorgan Chase & Co. | 0.00% | Add +4.4% | 14,359 | $95K |
| Scientech Research LLC | 0.03% | New | 13,502 | $90K |
| FMR LLC | 0.00% | Add +14.3% | 13,433 | $89K |
| D. E. Shaw & Co. | 0.00% | New | 12,818 | $85K |
| T. Rowe Price Associates Inc. | 0.00% | Add +14.8% | 11,965 | $80K |
| Intech Investment Management LLC | 0.00% | Reduce -13.2% | 11,871 | $79K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -15.0% | 11,453 | $76K |
| Ethic Inc. | 0.00% | Add +5.5% | 11,319 | $75K |
| Los Angeles Capital Management LLC | 0.00% | New | 11,075 | $74K |
| Commonwealth Equity Services, LLC | 0.00% | Add +6.9% | 10,890 | $72K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +42.0% | 9,466 | $63K |
| Citigroup Inc. | 0.00% | Reduce -49.6% | 7,432 | $49K |
| Royal Bank of Canada | 0.00% | Add +118.3% | 6,849 | $46K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 6,040 | $40K |
| Arax Advisory Partners | 0.00% | New | 4,551 | $30K |
| New York State Common Retirement Fund | 0.00% | No change | 4,187 | $28K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -26.6% | 3,737 | $25K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 2,765 | $18K |
| Cubist Systematic Strategies, LLC | 0.00% | New | 2,506 | $17K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 2,387 | $16K |
| Russell Investments Group, Ltd. | 0.00% | Add +930.6% | 2,257 | $15K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +62.9% | 2,088 | $14K |
| Legal & General Group Plc | 0.00% | No change | 2,032 | $13K |
| California State Teachers Retirement System | 0.00% | Add +0.1% | 1,736 | $12K |
| Sterling Capital Management LLC | 0.00% | Add +168.7% | 1,733 | $12K |
| GF Fund Management Co. LTD. | 0.00% | Add +41.7% | 1,162 | $8K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +11.3% | 731 | $5K |
| PNC Financial Services Group, Inc. | 0.00% | New | 673 | $4K |
| Amalgamated Bank | 0.00% | No change | 623 | $4K |
| Essential Partners LLC | 0.00% | Add +170.7% | 471 | $3K |
| Simplex Trading, LLC | 0.00% | New | 499 | $3K |
| Optiver Holding B.V. | 0.00% | New | 312 | $2K |
| Allworth Financial LP | 0.00% | New | 307 | $2K |
| Clearstead Advisors, LLC | 0.00% | New | 304 | $2K |
| True Wealth Design, LLC | 0.00% | Add +7433.3% | 226 | $2K |
"% of holder's portfolio" is LXEO's weight in each manager's 13F, not the share of Lexeo Therapeutics Inc. the manager owns.