Lexeo TherapeuticsLXEO
13F holders, Q1 2026 (March 31)139holders −7
16new positions
25sold out
5famous investors
$5.74avg. 13F price*
At the end of Q1 2026, 139 institutions reported holding Lexeo Therapeutics Inc. (LXEO) in their 13F filings, down 7 from Q4 2025. 16 opened new positions and 25 sold out. The largest holders were Paradigm Biocapital Advisors LP ($35.5M), BlackRock, Inc. ($29.3M) and Affinity Asset Advisors, LLC ($29.0M). 5 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Lexeo Therapeutics Inc.
- CUSIP
- 52886X107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 16 | $3.1M |
| Exits | 25 | $28.2M |
All 13F filers, Q4 2025 → Q1 2026: 11,010,450 shares bought and 7,618,595 shares sold, net +3,391,855 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 139 holders
| Paradigm Biocapital Advisors LP | 0.73% | Add +29.8% | 6,184,134 | $35.5M |
| BlackRock, Inc. | 0.00% | Add +4.1% | 5,110,871 | $29.3M |
| Affinity Asset Advisors, LLC | 1.73% | Add +57.8% | 5,050,211 | $29.0M |
| Ra Capital Management, L.P. | 0.30% | No change | 5,000,000 | $28.7M |
| Janus Henderson Group PLC | 0.01% | Reduce -9.7% | 4,976,429 | $28.5M |
| Vestal Point Capital, LP | 0.72% | No change | 4,475,000 | $25.7M |
| Frazier Life Sciences Management, L.P. | 0.66% | No change | 4,424,725 | $25.4M |
| Citadel Advisors | 0.02% | Add +1.6% | 3,834,999 | $22.0M |
| Orbimed Advisors LLC | 0.47% | Add +69.5% | 3,602,450 | $20.7M |
| State Street Corp. | 0.00% | Add +11.9% | 3,568,242 | $20.5M |
| Vanguard Capital Management LLC | 0.00% | — | 3,007,093 | $17.3M |
| Woodline Partners LP | 0.06% | Reduce -14.0% | 2,750,532 | $15.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +149.4% | 1,949,885 | $11.2M |
| Avoro Capital Advisors LLC | 0.11% | Reduce -43.2% | 1,875,000 | $10.8M |
| Point72 Asset Management | 0.02% | Reduce -11.3% | 1,680,449 | $9.6M |
| Millennium Management | 0.01% | Add +77.6% | 1,612,780 | $9.3M |
| Balyasny Asset Management L.P. | 0.02% | Reduce -2.8% | 1,589,585 | $9.1M |
| Geode Capital Management, LLC | 0.00% | Add +4.7% | 1,513,777 | $8.7M |
| ADAR1 Capital Management, LLC | 0.51% | Add +5.3% | 1,467,350 | $8.4M |
| Montanova Capital, LLC | 0.19% | No change | 1,250,000 | $7.2M |
| 683 Capital Management, LLC | 0.67% | Add +7.1% | 1,200,000 | $6.9M |
| Nantahala Capital Management, LLC | 0.43% | Add +20.0% | 1,200,000 | $6.9M |
| Dimensional Fund Advisors LP | 0.00% | Add +27.9% | 1,103,584 | $6.3M |
| Octagon Capital Advisors LP | 0.70% | Reduce -36.2% | 1,100,000 | $6.3M |
| Spruce Street Capital LP | 1.28% | Add +430.6% | 928,593 | $5.3M |
| Blackstone Inc. | 0.02% | No change | 904,959 | $5.2M |
| Vanguard Portfolio Management LLC | 0.00% | — | 577,192 | $3.3M |
| Ikarian Capital, LLC | 0.42% | No change | 513,011 | $2.9M |
| Northern Trust Corp. | 0.00% | Add +8.0% | 493,666 | $2.8M |
| Bank of America Corp. | 0.00% | Add +206.7% | 491,532 | $2.8M |
| Qube Research & Technologies Ltd | 0.00% | Add +249.3% | 465,515 | $2.7M |
| Morgan Stanley | 0.00% | Add +187.4% | 402,924 | $2.3M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 384,734 | $2.2M |
| DAFNA Capital Management LLC | 0.50% | Add +10.6% | 377,059 | $2.2M |
| AQR Capital Management | 0.00% | Add +0.7% | 339,623 | $1.9M |
| UBS Group AG | 0.00% | Add +14.5% | 321,737 | $1.8M |
| Squarepoint Ops LLC | 0.00% | Add +244.6% | 319,090 | $1.8M |
| Aberdeen Group plc | 0.00% | New | 245,904 | $1.4M |
| BNP Paribas Financial Markets | 0.00% | Reduce -11.3% | 228,201 | $1.3M |
| Privium Fund Management B.V. | 0.24% | Add +6.5% | 205,000 | $1.2M |
| Nuveen, LLC | 0.00% | Reduce -13.5% | 182,975 | $1.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -5.3% | 182,069 | $1.0M |
| Two Sigma Investments, LP | 0.00% | Reduce -54.6% | 181,676 | $1.0M |
| Wellington Management Group LLP | 0.00% | Add +107.5% | 172,703 | $991K |
| Bank of New York Mellon Corp | 0.00% | Reduce -4.7% | 158,899 | $912K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | Reduce -38.3% | 142,571 | $818K |
| Boothbay Fund Management, LLC | 0.02% | No change | 136,377 | $783K |
| Burkehill Global Management, LP | 0.04% | No change | 125,000 | $718K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | Add +331.1% | 112,982 | $649K |
| ExodusPoint Capital Management, LP | 0.01% | New | 112,172 | $644K |
| Alliancebernstein L.P. | 0.00% | No change | 61,810 | $614K |
| Rafferty Asset Management, LLC | 0.00% | Reduce -1.2% | 100,896 | $579K |
| XTX Topco Ltd | 0.01% | Add +802.8% | 100,607 | $577K |
| JPMorgan Chase & Co. | 0.00% | Add +212.0% | 93,163 | $491K |
| Rhumbline Advisers | 0.00% | Add +3.9% | 72,082 | $414K |
| Creative Planning | 0.00% | Add +547.6% | 67,079 | $385K |
| Invesco Ltd. | 0.00% | Reduce -86.3% | 63,518 | $365K |
| Deutsche Bank AG | 0.00% | Add +10.3% | 63,051 | $362K |
| DRW Securities, LLC | 0.01% | New | 47,988 | $275K |
| Bleakley Financial Group, LLC | 0.00% | New | 47,964 | $275K |
| Susquehanna International Group, LLP | 0.00% | Add +27.0% | 46,998 | $270K |
| Profund Advisors LLC | 0.01% | Add +18.7% | 45,161 | $259K |
| T. Rowe Price Associates Inc. | 0.00% | Add +27.3% | 43,132 | $248K |
| Vanguard Global Advisers, LLC | 0.00% | — | 42,575 | $244K |
| Los Angeles Capital Management LLC | 0.00% | Add +220.8% | 37,071 | $213K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +5.2% | 37,071 | $209K |
| MetLife Investment Management, LLC | 0.00% | Reduce -0.4% | 35,584 | $204K |
| Gsa Capital Partners LLP | 0.01% | Add +198.9% | 34,269 | $197K |
| Panagora Asset Management Inc. | 0.00% | No change | 34,297 | $197K |
| D. E. Shaw & Co. | 0.00% | Reduce -93.7% | 30,477 | $175K |
| Virtus Investment Advisers, LLC | 0.04% | Add +2.5% | 27,910 | $160K |
| Axq Capital, LP | 0.02% | New | 26,119 | $150K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | Reduce -2.4% | 25,577 | $147K |
| Wells Fargo & Company | 0.00% | Reduce -64.7% | 24,993 | $143K |
| FMR LLC | 0.00% | Add +82.2% | 24,388 | $140K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 24,221 | $139K |
| Cerity Partners LLC | 0.00% | Reduce -6.3% | 21,027 | $121K |
| Soltis Investment Advisors LLC | 0.01% | No change | 20,000 | $115K |
| New York State Common Retirement Fund | 0.00% | No change | 19,887 | $114K |
| Cwm, LLC | 0.00% | Reduce -3.4% | 18,317 | $105K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -7.4% | 17,738 | $102K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +6.9% | 17,565 | $101K |
| EntryPoint Capital, LLC | 0.03% | New | 16,560 | $95K |
| Intech Investment Management LLC | 0.00% | Add +16.3% | 16,504 | $95K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 16,373 | $94K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +11.6% | 15,991 | $91K |
| Raymond James Financial Inc. | 0.00% | Add +24.3% | 15,585 | $89K |
| Caxton Corp. | 1.99% | No change | 13,943 | $80K |
| Commonwealth Equity Services, LLC | 0.00% | Add +21.2% | 13,620 | $78K |
| Bridgeway Capital Management, LLC | 0.00% | No change | 13,400 | $77K |
| Citigroup Inc. | 0.00% | Reduce -12.9% | 13,320 | $76K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +8.9% | 12,952 | $74K |
| ProShare Advisors LLC | 0.00% | Reduce -12.9% | 12,852 | $74K |
| E Fund Management Co., Ltd. | 0.00% | — | 12,683 | $73K |
| Barclays PLC | 0.00% | Reduce -93.6% | 12,165 | $70K |
| Virtu Financial LLC | 0.00% | New | 11,901 | $68K |
| Ethic Inc. | 0.00% | Reduce -2.8% | 11,132 | $64K |
| Voya Investment Management LLC | 0.00% | Reduce -2.5% | 10,705 | $61K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +1048.3% | 9,485 | $54K |
| Russell Investments Group, Ltd. | 0.00% | Add +13.1% | 6,639 | $38K |
"% of holder's portfolio" is LXEO's weight in each manager's 13F, not the share of Lexeo Therapeutics Inc. the manager owns.