Lexicon PharmaceuticalsLXRX
13F holders, Q1 2025 (March 31)127holders
31new positions
29sold out
2famous investors
$0.46avg. 13F price*
At the end of Q1 2025, 127 institutions reported holding Lexicon Pharmaceuticals Inc. (LXRX) in their 13F filings, unchanged from Q4 2024. 31 opened new positions and 29 sold out. The largest holders were Artal Group S.A. ($62.6M), Siren, L.L.C. ($17.9M) and FMR LLC ($15.9M). 2 famous investors held it, including Cliff Asness (0.0% of AQR Capital Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Lexicon Pharmaceuticals Inc.
- CUSIP
- 528872302
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 31 | $3.3M |
| Exits | 29 | $10.7M |
All 13F filers, Q4 2024 → Q1 2025: 10,806,338 shares bought and 41,594,926 shares sold, net −30,788,588 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 127 holders
| Artal Group S.A. | 7.08% | No change | 136,180,481 | $62.6M |
| Siren, L.L.C. | 1.01% | No change | 38,918,903 | $17.9M |
| FMR LLC | 0.00% | Reduce -33.5% | 34,543,197 | $15.9M |
| BlackRock, Inc. | 0.00% | Reduce -3.1% | 10,013,007 | $4.6M |
| Vanguard Group Inc. | 0.00% | Reduce -3.3% | 9,557,175 | $4.4M |
| Schonfeld Strategic Advisors LLC | 0.03% | Add +8.7% | 8,212,993 | $3.8M |
| Geode Capital Management, LLC | 0.00% | Add +4.8% | 3,689,271 | $1.7M |
| State Street Corp. | 0.00% | Reduce -4.1% | 2,607,574 | $1.2M |
| CIBC Private Wealth Group LLC | 0.00% | New | 2,240,000 | $1.1M |
| UBS Group AG | 0.00% | Add +205.4% | 2,095,340 | $966K |
| Ikarian Capital, LLC | 0.21% | Reduce -8.5% | 1,417,952 | $653K |
| AQR Capital Management | 0.00% | New | 1,173,225 | $541K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.4% | 1,150,771 | $530K |
| Tang Capital Management LLC | 0.03% | Add +35.3% | 1,150,268 | $530K |
| Northern Trust Corp. | 0.00% | Reduce -15.2% | 1,109,887 | $511K |
| Susquehanna International Group, LLP | 0.00% | Add +72.7% | 951,135 | $438K |
| Hennion & Walsh Asset Management, Inc. | 0.02% | Reduce -3.9% | 830,054 | $382K |
| Gsa Capital Partners LLP | 0.03% | New | 807,492 | $372K |
| Monaco Asset Management SAM | 0.17% | New | 734,148 | $338K |
| Morgan Stanley | 0.00% | Add +21.9% | 641,629 | $296K |
| Acadian Asset Management LLC | 0.00% | New | 573,688 | $263K |
| BBR Partners, LLC | 0.02% | Add +21.3% | 570,000 | $263K |
| Nantahala Capital Management, LLC | 0.02% | Reduce -93.0% | 460,850 | $212K |
| Boothbay Fund Management, LLC | 0.01% | Reduce -5.4% | 454,891 | $210K |
| Virtus Investment Advisers, LLC | 0.06% | New | 436,672 | $201K |
| Group One Trading LLC | 0.01% | Add +16.4% | 365,806 | $169K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -34.3% | 355,152 | $164K |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.5% | 310,119 | $143K |
| Invesco Ltd. | 0.00% | Add +173.5% | 285,759 | $132K |
| Alliancebernstein L.P. | 0.00% | No change | 246,121 | $113K |
| Squarepoint Ops LLC | 0.00% | New | 195,409 | $90K |
| Ieq Capital, LLC | 0.00% | New | 177,302 | $82K |
| Simplex Trading, LLC | 0.00% | Add +82.1% | 174,982 | $80K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.02% | New | 171,147 | $79K |
| Cerity Partners LLC | 0.00% | Add +76.5% | 170,387 | $79K |
| Barclays PLC | 0.00% | Reduce -40.0% | 146,071 | $67K |
| Rhumbline Advisers | 0.00% | Reduce -10.4% | 137,230 | $63K |
| Compagnie Lombard Odier SCmA | 0.00% | No change | 110,000 | $51K |
| Cwm, LLC | 0.00% | Add +9228.4% | 105,504 | $49K |
| Bank of Montreal | 0.00% | Add +42.9% | 100,000 | $46K |
| Citigroup Inc. | 0.00% | Reduce -9.2% | 96,968 | $45K |
| Bank of America Corp. | 0.00% | Reduce -29.3% | 96,387 | $44K |
| Deutsche Bank AG | 0.00% | Reduce -70.1% | 94,394 | $43K |
| T. Rowe Price Associates Inc. | 0.00% | Add +19.0% | 92,248 | $43K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -10.2% | 90,864 | $42K |
| BNP Paribas Financial Markets | 0.00% | Add +352.3% | 89,114 | $41K |
| JPMorgan Chase & Co. | 0.00% | Add +0.7% | 88,199 | $41K |
| Intech Investment Management LLC | 0.00% | Add +30.3% | 73,853 | $34K |
| China Universal Asset Management Co., Ltd. | 0.00% | Reduce -5.4% | 72,509 | $33K |
| LPL Financial LLC | 0.00% | Add +24.5% | 70,957 | $33K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | New | 69,207 | $32K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.4% | 68,683 | $32K |
| SG Americas Securities, LLC | 0.00% | Add +23.0% | 68,012 | $31K |
| KWB Wealth | 0.00% | No change | 40,640 | $30K |
| Wells Fargo & Company | 0.00% | Add +2.3% | 63,928 | $29K |
| Straight Path Wealth Management | 0.01% | New | 62,666 | $29K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 56,248 | $26K |
| Pinnacle Associates Ltd. | 0.00% | Reduce -96.2% | 54,180 | $25K |
| Wedbush Securities Inc. | 0.00% | No change | 40,850 | $19K |
| ProShare Advisors LLC | 0.00% | Reduce -16.8% | 41,162 | $19K |
| Fortis Group Advisors, LLC | 0.00% | New | 37,800 | $17K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +58.2% | 36,736 | $17K |
| Pallas Capital Advisors LLC | 0.00% | New | 36,208 | $17K |
| University of Texas/Texas Am Investment Management Co. | 0.00% | No change | 35,714 | $16K |
| New York State Common Retirement Fund | 0.00% | No change | 33,702 | $16K |
| Captrust Financial Advisors | 0.00% | Add +148.4% | 33,184 | $15K |
| Pathstone Holdings, LLC | 0.00% | Reduce -41.9% | 31,397 | $14K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 29,715 | $14K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +131.2% | 28,107 | $13K |
| Cibc World Markets Corp. | 0.00% | Add +137.1% | 25,477 | $12K |
| SIH Partners, LLLP | 0.00% | New | 23,712 | $11K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -6.5% | 22,075 | $10K |
| Victory Capital Management Inc. | 0.00% | Add +3.7% | 21,633 | $10K |
| Steward Partners Investment Advisory, LLC | 0.00% | Add +5230.8% | 21,323 | $10K |
| Simplicity Wealth,LLC | 0.00% | New | 20,447 | $9K |
| Oppenheimer & Co. Inc. | 0.00% | New | 20,100 | $9K |
| Invera Wealth Advisors, LLC | 0.01% | New | 20,000 | $9K |
| Tiaa Trust, National Association | 0.00% | No change | 20,000 | $9K |
| Ethic Inc. | 0.00% | New | 17,259 | $8K |
| HSBC Holdings PLC | 0.00% | Reduce -0.6% | 13,415 | $8K |
| Merit Financial Group, LLC | 0.00% | New | 15,492 | $7K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.4% | 12,096 | $7K |
| Truist Financial Corp. | 0.00% | No change | 14,000 | $6K |
| Voya Investment Management LLC | 0.00% | Reduce -63.8% | 13,922 | $6K |
| Cubist Systematic Strategies, LLC | 0.00% | New | 13,797 | $6K |
| Point72 (DIFC) Ltd | 0.00% | New | 13,327 | $6K |
| XTX Topco Ltd | 0.00% | New | 12,471 | $6K |
| Focus Partners Advisor Solutions, LLC | 0.00% | New | 12,096 | $6K |
| Chemistry Wealth Management LLC | 0.00% | No change | 12,000 | $6K |
| Raymond James Financial Inc. | 0.00% | No change | 11,912 | $5K |
| Avantax Advisory Services, Inc. | 0.00% | New | 11,724 | $5K |
| North Star Asset Management Inc. | 0.00% | No change | 11,500 | $5K |
| Legal & General Group Plc | 0.00% | Reduce -89.7% | 11,466 | $5K |
| Chaney Capital Management, Inc. | 0.00% | New | 11,167 | $5K |
| Berger Financial Group, Inc | 0.00% | No change | 10,929 | $5K |
| Unique Wealth Strategies, LLC | 0.00% | No change | 10,000 | $5K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 8,867 | $4K |
| California State Teachers Retirement System | 0.00% | Reduce -95.7% | 8,319 | $4K |
| Golden State Wealth Management, LLC | 0.00% | New | 3,700 | $2K |
| SBI Securities Co., Ltd. | 0.00% | Add +8.4% | 3,320 | $2K |
| Jones Financial Companies LLLP | 0.00% | Add +1338.0% | 2,042 | $1K |
| Amalgamated Bank | 0.00% | No change | 2,409 | $1K |
| Royal Bank of Canada | 0.00% | Reduce -68.1% | 3,159 | $1K |
| Daiwa Securities Group Inc. | 0.00% | No change | 1,369 | $1K |
| Quintet Private Bank (Europe) S.A. | 0.00% | No change | 1,928 | $888 |
| Optiver Holding B.V. | 0.00% | Add +53.6% | 1,843 | $849 |
| PNC Financial Services Group, Inc. | 0.00% | Add +1216.2% | 1,461 | $673 |
| Coldstream Capital Management Inc. | 0.00% | New | 1,388 | $640 |
| Rialto Wealth Management, LLC | 0.00% | New | 1,313 | $606 |
| Sterling Capital Management LLC | 0.00% | Reduce -48.3% | 1,280 | $590 |
| US Bancorp \de | 0.00% | Reduce -33.4% | 1,082 | $499 |
| Pinney & Scofield, Inc. | 0.00% | No change | 1,000 | $461 |
| Osaic Holdings, Inc. | 0.00% | Add +26.9% | 942 | $433 |
| EverSource Wealth Advisors, LLC | 0.00% | Add +2806.3% | 930 | $429 |
| True Wealth Design, LLC | 0.00% | New | 619 | $286 |
| Nisa Investment Advisors, LLC | 0.00% | New | 600 | $276 |
| Northwestern Mutual Wealth Management Co. | 0.00% | No change | 500 | $230 |
| Citadel Advisors | 0.00% | Reduce -98.4% | 406 | $187 |
| SJS Investment Consulting Inc. | 0.00% | No change | 400 | $185 |
| Syntax Research, Inc. | 0.00% | No change | 142 | $66 |
| Comerica Bank | 0.00% | No change | 122 | $56 |
| Larson Financial Group LLC | 0.00% | No change | 100 | $46 |
| CBIZ Investment Advisory Services, LLC | 0.00% | No change | 71 | $33 |
| NewEdge Advisors, LLC | 0.00% | No change | 5 | $2 |
| Farther Finance Advisors, LLC | 0.00% | No change | 2 | $1 |
| Avion Wealth | 0.00% | New | 1,134 | $0 |
| Covestor Ltd | 0.00% | No change | 81 | $0 |
"% of holder's portfolio" is LXRX's weight in each manager's 13F, not the share of Lexicon Pharmaceuticals Inc. the manager owns.