Lexicon PharmaceuticalsLXRX
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 127 institutions reported holding Lexicon Pharmaceuticals Inc. (LXRX) in their 13F filings, down 10 from Q3 2024. 19 opened new positions and 34 sold out. The largest holders were Artal Group S.A. ($100.8M), FMR LLC ($38.4M) and Siren, L.L.C. ($28.8M). 3 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Lexicon Pharmaceuticals Inc.
- CUSIP
- 528872302
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 19 | $2.0M |
| Exits | 34 | $27.8M |
All 13F filers, Q3 2024 → Q4 2024: 28,490,847 shares bought and 19,500,105 shares sold, net +8,990,742 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 127 holders
| Artal Group S.A. | 8.59% | No change | 136,180,481 | $100.8M |
| FMR LLC | 0.00% | Add +4.2% | 51,970,455 | $38.4M |
| Siren, L.L.C. | 1.27% | No change | 38,918,903 | $28.8M |
| BlackRock, Inc. | 0.00% | Add +2.0% | 10,333,158 | $7.6M |
| Vanguard Group Inc. | 0.00% | Add +22.1% | 9,881,728 | $7.3M |
| Point72 Asset Management | 0.02% | Add +630.7% | 8,988,421 | $6.6M |
| Schonfeld Strategic Advisors LLC | 0.04% | Add +301.5% | 7,558,621 | $5.6M |
| Nantahala Capital Management, LLC | 0.34% | Add +186.6% | 6,604,150 | $4.9M |
| Geode Capital Management, LLC | 0.00% | Reduce -0.1% | 3,521,255 | $2.6M |
| State Street Corp. | 0.00% | Add +10.0% | 2,718,248 | $2.0M |
| NEA Management Company, LLC | 0.10% | No change | 2,382,286 | $1.8M |
| Ikarian Capital, LLC | 0.33% | New | 1,550,000 | $1.1M |
| Pinnacle Associates Ltd. | 0.01% | Reduce -17.6% | 1,425,292 | $1.1M |
| Northern Trust Corp. | 0.00% | Add +14.4% | 1,308,651 | $966K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -16.0% | 1,191,091 | $880K |
| Nuveen Asset Management, LLC | 0.00% | No change | 1,103,840 | $815K |
| Hennion & Walsh Asset Management, Inc. | 0.03% | Add +18.1% | 863,255 | $638K |
| Tang Capital Management LLC | 0.04% | Add +750.3% | 850,268 | $628K |
| Wellington Management Group LLP | 0.00% | Add +2.1% | 747,996 | $552K |
| UBS Group AG | 0.00% | Add +390.1% | 686,117 | $507K |
| Susquehanna International Group, LLP | 0.00% | Add +529.6% | 550,891 | $407K |
| Goldman Sachs Group Inc. | 0.00% | Add +34.6% | 540,207 | $399K |
| Morgan Stanley | 0.00% | Add +15.6% | 526,150 | $389K |
| Boothbay Fund Management, LLC | 0.01% | New | 480,822 | $355K |
| BBR Partners, LLC | 0.02% | No change | 470,000 | $347K |
| Swiss National Bank | 0.00% | Add +34.4% | 426,600 | $315K |
| Virtus Advisers, LLC | 0.13% | Add +136.3% | 425,269 | $314K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +193.6% | 353,508 | $261K |
| Deutsche Bank AG | 0.00% | Add +378.0% | 315,659 | $234K |
| Bank of New York Mellon Corp | 0.00% | Add +0.0% | 314,919 | $233K |
| Group One Trading LLC | 0.01% | New | 314,404 | $232K |
| Alliancebernstein L.P. | 0.00% | Reduce -9.9% | 246,121 | $182K |
| Barclays PLC | 0.00% | Add +25.5% | 243,316 | $180K |
| Woodline Partners LP | 0.00% | Reduce -81.1% | 229,376 | $169K |
| Jane Street Group, LLC | 0.00% | Add +158.0% | 220,264 | $163K |
| California State Teachers Retirement System | 0.00% | Add +29.9% | 195,215 | $144K |
| Rhumbline Advisers | 0.00% | Add +4.9% | 153,151 | $113K |
| Bank of America Corp. | 0.00% | Add +27.4% | 136,407 | $101K |
| Stifel Financial Corp. | 0.00% | Add +117.0% | 112,853 | $83K |
| Legal & General Group Plc | 0.00% | No change | 111,403 | $82K |
| Compagnie Lombard Odier SCmA | 0.00% | Add +10.0% | 110,000 | $81K |
| Citigroup Inc. | 0.00% | Add +19.0% | 106,786 | $79K |
| Invesco Ltd. | 0.00% | Add +60.6% | 104,494 | $77K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -7.0% | 101,148 | $75K |
| Cerity Partners LLC | 0.00% | Add +328.7% | 96,512 | $71K |
| Simplex Trading, LLC | 0.00% | New | 96,083 | $71K |
| Virtu Financial LLC | 0.00% | New | 88,982 | $66K |
| JPMorgan Chase & Co. | 0.00% | Reduce -2.3% | 87,617 | $65K |
| KWB Wealth | 0.01% | No change | 40,640 | $64K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -33.9% | 77,502 | $57K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +10.2% | 76,650 | $57K |
| Bank of Montreal | 0.00% | Reduce 0.0% | 70,000 | $52K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.5% | 65,782 | $49K |
| Teacher Retirement System of Texas | 0.00% | Add +60.3% | 65,415 | $48K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -14.6% | 64,966 | $48K |
| Arizona State Retirement System | 0.00% | Add +34.5% | 62,976 | $47K |
| Wells Fargo & Company | 0.00% | Reduce -18.3% | 62,523 | $46K |
| Corebridge Financial, Inc. | 0.00% | Reduce -7.0% | 57,082 | $42K |
| LPL Financial LLC | 0.00% | Reduce -9.6% | 57,007 | $42K |
| Intech Investment Management LLC | 0.00% | Reduce -22.8% | 56,689 | $42K |
| SG Americas Securities, LLC | 0.00% | Add +20.0% | 55,308 | $41K |
| Pathstone Holdings, LLC | 0.00% | Reduce -8.3% | 54,051 | $40K |
| Renaissance Technologies | 0.00% | New | 51,141 | $38K |
| ProShare Advisors LLC | 0.00% | Add +14.9% | 49,460 | $37K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 46,013 | $34K |
| Rpo LLC | 0.05% | New | 44,242 | $33K |
| Bayesian Capital Management, LP | 0.00% | New | 42,000 | $31K |
| Wedbush Securities Inc. | 0.00% | No change | 40,850 | $30K |
| Voya Investment Management LLC | 0.00% | No change | 38,418 | $28K |
| University of Texas/Texas Am Investment Management Co. | 0.00% | No change | 35,714 | $26K |
| New York State Common Retirement Fund | 0.00% | No change | 33,702 | $25K |
| Kestra Advisory Services, LLC | 0.00% | Add +103.2% | 31,500 | $23K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | — | 29,715 | $22K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -38.3% | 29,646 | $22K |
| KLP Kapitalforvaltning As | 0.00% | — | 26,200 | $19K |
| Citadel Advisors | 0.00% | Reduce -73.8% | 25,832 | $19K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +16.6% | 23,223 | $17K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | New | 23,613 | $17K |
| Victory Capital Management Inc. | 0.00% | Reduce -52.9% | 20,859 | $15K |
| Tiaa Trust, National Association | 0.00% | Reduce -26.1% | 20,000 | $15K |
| BNP Paribas Financial Markets | 0.00% | Reduce -38.1% | 19,704 | $15K |
| State of Wisconsin Investment Board | 0.00% | Add +20.9% | 15,034 | $11K |
| Truist Financial Corp. | 0.00% | Add +4.5% | 14,000 | $10K |
| Vermillion & White Wealth Management Group, LLC | 0.01% | No change | 13,415 | $10K |
| Captrust Financial Advisors | 0.00% | Add +17.7% | 13,358 | $10K |
| HSBC Holdings PLC | 0.00% | New | 13,502 | $10K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -7.9% | 12,046 | $9K |
| Pinnacle Wealth Management Advisory Group, LLC | 0.00% | No change | 12,445 | $9K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +103.6% | 12,155 | $9K |
| Chemistry Wealth Management LLC | 0.00% | No change | 12,000 | $9K |
| Raymond James Financial Inc. | 0.00% | — | 11,912 | $9K |
| North Star Asset Management Inc. | 0.00% | Reduce -8.4% | 11,500 | $8K |
| Berger Financial Group, Inc | 0.00% | No change | 10,929 | $8K |
| Cibc World Markets Corp. | 0.00% | New | 10,744 | $8K |
| Unique Wealth Strategies, LLC | 0.00% | New | 10,000 | $7K |
| Estabrook Capital Management | 0.00% | No change | 10,000 | $7K |
| Royal Bank of Canada | 0.00% | Reduce -13.1% | 9,911 | $7K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 8,867 | $7K |
| Nordwand Advisors, LLC | 0.00% | No change | 4,000 | $3K |
| SBI Securities Co., Ltd. | 0.00% | — | 3,064 | $2K |
"% of holder's portfolio" is LXRX's weight in each manager's 13F, not the share of Lexicon Pharmaceuticals Inc. the manager owns.