Lexicon PharmaceuticalsLXRX

13F holders, Q4 2024 (December 31)
127holders −10
19new positions
34sold out
3famous investors
$0.74avg. 13F price*

At the end of Q4 2024, 127 institutions reported holding Lexicon Pharmaceuticals Inc. (LXRX) in their 13F filings, down 10 from Q3 2024. 19 opened new positions and 34 sold out. The largest holders were Artal Group S.A. ($100.8M), FMR LLC ($38.4M) and Siren, L.L.C. ($28.8M). 3 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Lexicon Pharmaceuticals Inc.
CUSIP
528872302
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 118Q1 2024Q2 2024: 127Q2 2024Q3 2024: 137Q3 2024Q4 2024: 127Q4 2024Q1 2025: 127Q1 2025Q2 2025: 123Q2 2025Q3 2025: 123Q3 2025Q4 2025: 125Q4 2025Q1 2026: 136Q1 2026Q2 2026: 149Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions19$2.0M
Exits34$27.8M

All 13F filers, Q3 2024 → Q4 2024: 28,490,847 shares bought and 19,500,105 shares sold, net +8,990,742 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 127 holders

Artal Group S.A. 8.59% No change 136,180,481 $100.8M
FMR LLC 0.00% Add +4.2% 51,970,455 $38.4M
Siren, L.L.C. 1.27% No change 38,918,903 $28.8M
BlackRock, Inc. 0.00% Add +2.0% 10,333,158 $7.6M
Vanguard Group Inc. 0.00% Add +22.1% 9,881,728 $7.3M
Point72 Asset Management 0.02% Add +630.7% 8,988,421 $6.6M
Schonfeld Strategic Advisors LLC 0.04% Add +301.5% 7,558,621 $5.6M
Nantahala Capital Management, LLC 0.34% Add +186.6% 6,604,150 $4.9M
Geode Capital Management, LLC 0.00% Reduce -0.1% 3,521,255 $2.6M
State Street Corp. 0.00% Add +10.0% 2,718,248 $2.0M
NEA Management Company, LLC 0.10% No change 2,382,286 $1.8M
Ikarian Capital, LLC 0.33% New 1,550,000 $1.1M
Pinnacle Associates Ltd. 0.01% Reduce -17.6% 1,425,292 $1.1M
Northern Trust Corp. 0.00% Add +14.4% 1,308,651 $966K
Charles Schwab Investment Management Inc. 0.00% Reduce -16.0% 1,191,091 $880K
Nuveen Asset Management, LLC 0.00% No change 1,103,840 $815K
Hennion & Walsh Asset Management, Inc. 0.03% Add +18.1% 863,255 $638K
Tang Capital Management LLC 0.04% Add +750.3% 850,268 $628K
Wellington Management Group LLP 0.00% Add +2.1% 747,996 $552K
UBS Group AG 0.00% Add +390.1% 686,117 $507K
Susquehanna International Group, LLP 0.00% Add +529.6% 550,891 $407K
Goldman Sachs Group Inc. 0.00% Add +34.6% 540,207 $399K
Morgan Stanley 0.00% Add +15.6% 526,150 $389K
Boothbay Fund Management, LLC 0.01% New 480,822 $355K
BBR Partners, LLC 0.02% No change 470,000 $347K
Swiss National Bank 0.00% Add +34.4% 426,600 $315K
Virtus Advisers, LLC 0.13% Add +136.3% 425,269 $314K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +193.6% 353,508 $261K
Deutsche Bank AG 0.00% Add +378.0% 315,659 $234K
Bank of New York Mellon Corp 0.00% Add +0.0% 314,919 $233K
Group One Trading LLC 0.01% New 314,404 $232K
Alliancebernstein L.P. 0.00% Reduce -9.9% 246,121 $182K
Barclays PLC 0.00% Add +25.5% 243,316 $180K
Woodline Partners LP 0.00% Reduce -81.1% 229,376 $169K
Jane Street Group, LLC 0.00% Add +158.0% 220,264 $163K
California State Teachers Retirement System 0.00% Add +29.9% 195,215 $144K
Rhumbline Advisers 0.00% Add +4.9% 153,151 $113K
Bank of America Corp. 0.00% Add +27.4% 136,407 $101K
Stifel Financial Corp. 0.00% Add +117.0% 112,853 $83K
Legal & General Group Plc 0.00% No change 111,403 $82K
Compagnie Lombard Odier SCmA 0.00% Add +10.0% 110,000 $81K
Citigroup Inc. 0.00% Add +19.0% 106,786 $79K
Invesco Ltd. 0.00% Add +60.6% 104,494 $77K
Commonwealth Equity Services, LLC 0.00% Reduce -7.0% 101,148 $75K
Cerity Partners LLC 0.00% Add +328.7% 96,512 $71K
Simplex Trading, LLC 0.00% New 96,083 $71K
Virtu Financial LLC 0.00% New 88,982 $66K
JPMorgan Chase & Co. 0.00% Reduce -2.3% 87,617 $65K
KWB Wealth 0.01% No change 40,640 $64K
T. Rowe Price Associates Inc. 0.00% Reduce -33.9% 77,502 $57K
China Universal Asset Management Co., Ltd. 0.01% Add +10.2% 76,650 $57K
Bank of Montreal 0.00% Reduce 0.0% 70,000 $52K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +4.5% 65,782 $49K
Teacher Retirement System of Texas 0.00% Add +60.3% 65,415 $48K
Dimensional Fund Advisors LP 0.00% Reduce -14.6% 64,966 $48K
Arizona State Retirement System 0.00% Add +34.5% 62,976 $47K
Wells Fargo & Company 0.00% Reduce -18.3% 62,523 $46K
Corebridge Financial, Inc. 0.00% Reduce -7.0% 57,082 $42K
LPL Financial LLC 0.00% Reduce -9.6% 57,007 $42K
Intech Investment Management LLC 0.00% Reduce -22.8% 56,689 $42K
SG Americas Securities, LLC 0.00% Add +20.0% 55,308 $41K
Pathstone Holdings, LLC 0.00% Reduce -8.3% 54,051 $40K
Renaissance Technologies 0.00% New 51,141 $38K
ProShare Advisors LLC 0.00% Add +14.9% 49,460 $37K
CANADA LIFE ASSURANCE Co 0.00% No change 46,013 $34K
Rpo LLC 0.05% New 44,242 $33K
Bayesian Capital Management, LP 0.00% New 42,000 $31K
Wedbush Securities Inc. 0.00% No change 40,850 $30K
Voya Investment Management LLC 0.00% No change 38,418 $28K
University of Texas/Texas Am Investment Management Co. 0.00% No change 35,714 $26K
New York State Common Retirement Fund 0.00% No change 33,702 $25K
Kestra Advisory Services, LLC 0.00% Add +103.2% 31,500 $23K
Police & Firemen's Retirement System of New Jersey 0.00% — 29,715 $22K
Manufacturers Life Insurance Company, The 0.00% Reduce -38.3% 29,646 $22K
KLP Kapitalforvaltning As 0.00% — 26,200 $19K
Citadel Advisors 0.00% Reduce -73.8% 25,832 $19K
Vanguard Personalized Indexing Management, LLC 0.00% Add +16.6% 23,223 $17K
Cambridge Investment Research Advisors, Inc. 0.00% New 23,613 $17K
Victory Capital Management Inc. 0.00% Reduce -52.9% 20,859 $15K
Tiaa Trust, National Association 0.00% Reduce -26.1% 20,000 $15K
BNP Paribas Financial Markets 0.00% Reduce -38.1% 19,704 $15K
State of Wisconsin Investment Board 0.00% Add +20.9% 15,034 $11K
Truist Financial Corp. 0.00% Add +4.5% 14,000 $10K
Vermillion & White Wealth Management Group, LLC 0.01% No change 13,415 $10K
Captrust Financial Advisors 0.00% Add +17.7% 13,358 $10K
HSBC Holdings PLC 0.00% New 13,502 $10K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -7.9% 12,046 $9K
Pinnacle Wealth Management Advisory Group, LLC 0.00% No change 12,445 $9K
Tower Research Capital LLC (TRC) 0.00% Add +103.6% 12,155 $9K
Chemistry Wealth Management LLC 0.00% No change 12,000 $9K
Raymond James Financial Inc. 0.00% — 11,912 $9K
North Star Asset Management Inc. 0.00% Reduce -8.4% 11,500 $8K
Berger Financial Group, Inc 0.00% No change 10,929 $8K
Cibc World Markets Corp. 0.00% New 10,744 $8K
Unique Wealth Strategies, LLC 0.00% New 10,000 $7K
Estabrook Capital Management 0.00% No change 10,000 $7K
Royal Bank of Canada 0.00% Reduce -13.1% 9,911 $7K
Ameritas Investment Partners, Inc. 0.00% No change 8,867 $7K
Nordwand Advisors, LLC 0.00% No change 4,000 $3K
SBI Securities Co., Ltd. 0.00% — 3,064 $2K

"% of holder's portfolio" is LXRX's weight in each manager's 13F, not the share of Lexicon Pharmaceuticals Inc. the manager owns.

Show all 127 holders