MBX BiosciencesMBX

13F holders, Q4 2024 (December 31)
63holders +18
31new positions
15sold out
2famous investors
$18.41avg. 13F price*

At the end of Q4 2024, 63 institutions reported holding MBX Biosciences Inc. (MBX) in their 13F filings, up 18 from Q3 2024. 31 opened new positions and 15 sold out. The largest holders were Frazier Life Sciences Management, L.P. ($110.3M), Orbimed Advisors LLC ($70.3M) and NEA Management Company, LLC ($66.6M). 2 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
MBX Biosciences Inc.
CUSIP
55287L101
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q3 2024: 45Q3 2024Q4 2024: 63Q4 2024Q1 2025: 79Q1 2025Q2 2025: 88Q2 2025Q3 2025: 118Q3 2025Q4 2025: 138Q4 2025Q1 2026: 157Q1 2026Q2 2026: 172Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions31$28.9M
Exits15$9.4M

All 13F filers, Q3 2024 → Q4 2024: 3,323,038 shares bought and 689,308 shares sold, net +2,633,730 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 63 holders

Frazier Life Sciences Management, L.P. 4.59% No change 5,985,347 $110.3M
Orbimed Advisors LLC 1.46% No change 3,812,215 $70.3M
NEA Management Company, LLC 3.76% No change 3,614,486 $66.6M
Deep Track Capital, LP 2.09% No change 3,018,935 $55.6M
Wellington Management Group LLP 0.01% Reduce -1.0% 2,909,639 $53.0M
NVP Associates, LLC 21.06% No change 2,136,335 $39.4M
Driehaus Capital Management LLC 0.24% Add +61.2% 1,581,760 $29.2M
Ra Capital Management, L.P. 0.37% No change 1,511,334 $27.9M
EcoR1 Capital, LLC 0.93% Add +7.1% 1,259,273 $23.2M
T. Rowe Price Associates Inc. 0.00% Reduce -2.6% 1,161,527 $21.4M
BlackRock, Inc. 0.00% New 727,952 $13.4M
Cormorant Asset Management, LP 0.71% No change 700,000 $12.9M
Vanguard Group Inc. 0.00% Add +1241.9% 670,948 $12.4M
TCG Crossover Management, LLC 1.17% No change 650,000 $12.0M
Woodline Partners LP 0.08% Add +17.1% 608,721 $11.2M
Franklin Resources Inc. 0.00% Reduce -17.9% 369,300 $6.8M
Millennium Management 0.01% Reduce -24.2% 333,642 $6.1M
Geode Capital Management, LLC 0.00% Add +1093.2% 265,703 $4.9M
Citadel Advisors 0.00% Add +62.5% 220,330 $4.1M
Alyeska Investment Group, L.P. 0.01% Reduce -22.4% 174,700 $3.2M
Parkman Healthcare Partners LLC 0.42% New 170,000 $3.1M
Platinum Investment Management Ltd. 0.18% Add +8.1% 162,090 $3.0M
State Street Corp. 0.00% New 142,649 $2.6M
Charles Schwab Investment Management Inc. 0.00% New 93,311 $1.7M
Northern Trust Corp. 0.00% New 90,682 $1.7M
Schonfeld Strategic Advisors LLC 0.01% New 71,500 $1.3M
Manufacturers Life Insurance Company, The 0.00% Add +7.5% 49,675 $916K
UBS Group AG 0.00% New 45,901 $846K
TD Asset Management Inc 0.00% Reduce -18.3% 36,600 $675K
Goldman Sachs Group Inc. 0.00% Reduce -31.7% 34,827 $642K
Alps Advisors Inc. 0.00% New 27,020 $498K
Teachers Retirement System of the State of Kentucky 0.00% No change 26,708 $492K
Marshall Wace, LLP 0.00% Add +115.8% 25,900 $477K
Norges Bank 0.00% No change 25,000 $461K
FMR LLC 0.00% New 24,573 $453K
Bank of New York Mellon Corp 0.00% New 23,914 $441K
Morgan Stanley 0.00% New 23,835 $439K
Saturn V Capital Management LP 0.13% New 18,000 $332K
Barclays PLC 0.00% Add +6.3% 17,433 $321K
Bank of America Corp. 0.00% New 16,059 $296K
Nuveen Asset Management, LLC 0.00% New 14,471 $267K
BIT Capital GmbH 0.02% New 12,743 $235K
Rhumbline Advisers 0.00% New 9,472 $175K
JPMorgan Chase & Co. 0.00% New 9,106 $168K
Citigroup Inc. 0.00% New 8,864 $163K
MetLife Investment Management, LLC 0.00% New 7,230 $133K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% New 6,335 $117K
Wells Fargo & Company 0.00% New 5,844 $108K
Corebridge Financial, Inc. 0.00% New 5,593 $103K
Sandia Investment Management LP 0.18% No change 5,000 $92K
Deutsche Bank AG 0.00% New 4,338 $80K
Virtus Advisers, LLC 0.03% New 3,468 $64K
Police & Firemen's Retirement System of New Jersey 0.00% — 2,143 $39K
STRS Ohio 0.00% New 2,100 $39K
BNP Paribas Financial Markets 0.00% New 1,486 $27K
Ameritas Investment Partners, Inc. 0.00% New 1,177 $22K
Legal & General Group Plc 0.00% Reduce -77.9% 1,107 $20K
Royal Bank of Canada 0.00% New 833 $16K
California State Teachers Retirement System 0.00% New 832 $15K
Tower Research Capital LLC (TRC) 0.00% Add +421.4% 803 $15K
R Squared Ltd 0.01% — 400 $7K
Amalgamated Bank 0.00% New 384 $7K
Sterling Capital Management LLC 0.00% New 161 $3K

"% of holder's portfolio" is MBX's weight in each manager's 13F, not the share of MBX Biosciences Inc. the manager owns.