MBX BiosciencesMBX
13F holders, Q1 2025 (March 31)79holders +16
26new positions
10sold out
2famous investors
$7.38avg. 13F price*
At the end of Q1 2025, 79 institutions reported holding MBX Biosciences Inc. (MBX) in their 13F filings, up 16 from Q4 2024. 26 opened new positions and 10 sold out. The largest holders were Frazier Life Sciences Management, L.P. ($44.2M), Orbimed Advisors LLC ($29.5M) and NEA Management Company, LLC ($26.7M). 2 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- MBX Biosciences Inc.
- CUSIP
- 55287L101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 26 | $16.6M |
| Exits | 10 | $9.1M |
All 13F filers, Q4 2024 → Q1 2025: 3,768,359 shares bought and 1,043,624 shares sold, net +2,724,735 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 79 holders
| Frazier Life Sciences Management, L.P. | 2.02% | No change | 5,985,347 | $44.2M |
| Orbimed Advisors LLC | 0.71% | Add +5.0% | 4,002,887 | $29.5M |
| NEA Management Company, LLC | 2.05% | No change | 3,614,486 | $26.7M |
| Deep Track Capital, LP | 0.72% | No change | 3,018,935 | $22.3M |
| Wellington Management Group LLP | 0.00% | Reduce -9.3% | 2,638,521 | $19.5M |
| NVP Associates, LLC | 14.05% | No change | 2,136,335 | $15.8M |
| Driehaus Capital Management LLC | 0.11% | Reduce -0.2% | 1,579,207 | $11.7M |
| Ra Capital Management, L.P. | 0.19% | No change | 1,511,334 | $11.2M |
| EcoR1 Capital, LLC | 0.55% | No change | 1,259,273 | $9.3M |
| MPM Bioimpact LLC | 1.44% | New | 1,132,950 | $8.4M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -5.2% | 1,100,916 | $8.1M |
| Woodline Partners LP | 0.04% | Add +44.1% | 877,461 | $6.5M |
| BlackRock, Inc. | 0.00% | Add +7.6% | 783,042 | $5.8M |
| Cormorant Asset Management, LP | 0.39% | No change | 700,000 | $5.2M |
| Vanguard Group Inc. | 0.00% | Reduce -0.8% | 665,563 | $4.9M |
| TCG Crossover Management, LLC | 0.65% | No change | 650,000 | $4.8M |
| Franklin Resources Inc. | 0.00% | Add +0.0% | 369,315 | $2.7M |
| Parkman Healthcare Partners LLC | 0.29% | Add +93.1% | 328,323 | $2.4M |
| Geode Capital Management, LLC | 0.00% | Add +3.3% | 274,458 | $2.0M |
| Opaleye Management Inc. | 0.42% | New | 250,000 | $1.8M |
| JPMorgan Chase & Co. | 0.00% | Add +2109.9% | 201,235 | $1.5M |
| Schonfeld Strategic Advisors LLC | 0.01% | Add +180.6% | 200,642 | $1.5M |
| Platinum Investment Management Ltd. | 0.08% | Add +14.7% | 185,932 | $1.4M |
| State Street Corp. | 0.00% | Add +24.2% | 177,220 | $1.3M |
| Affinity Asset Advisors, LLC | 0.21% | New | 175,000 | $1.3M |
| Millennium Management | 0.00% | Reduce -48.9% | 170,440 | $1.3M |
| TD Asset Management Inc | 0.00% | Add +313.9% | 151,504 | $1.1M |
| Exome Asset Management LLC | 0.88% | New | 133,113 | $982K |
| Morgan Stanley | 0.00% | Add +380.9% | 114,610 | $846K |
| Marshall Wace, LLP | 0.00% | Add +329.4% | 111,211 | $821K |
| Point72 Asset Management | 0.00% | New | 110,482 | $815K |
| Citigroup Inc. | 0.00% | Add +998.0% | 97,328 | $718K |
| Stempoint Capital LP | 0.23% | New | 96,615 | $713K |
| Northern Trust Corp. | 0.00% | Add +6.4% | 96,507 | $712K |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.3% | 94,546 | $698K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +0.9% | 50,110 | $370K |
| Aaron Wealth Advisors LLC | 0.04% | New | 50,000 | $369K |
| Shay Capital LLC | 0.11% | New | 49,133 | $363K |
| FMR LLC | 0.00% | Add +80.0% | 44,240 | $326K |
| Prelude Capital Management, LLC | 0.03% | New | 40,225 | $297K |
| Two Sigma Investments, LP | 0.00% | New | 33,833 | $250K |
| Walleye Capital LLC | 0.00% | New | 32,490 | $240K |
| BNP Paribas Financial Markets | 0.00% | Add +1980.5% | 30,916 | $228K |
| Jump Financial, LLC | 0.00% | New | 28,996 | $214K |
| Bank of America Corp. | 0.00% | Add +74.9% | 28,090 | $207K |
| UBS Group AG | 0.00% | Reduce -40.1% | 27,499 | $203K |
| Alps Advisors Inc. | 0.00% | Reduce -3.6% | 26,034 | $192K |
| Bank of New York Mellon Corp | 0.00% | Reduce -0.0% | 23,910 | $176K |
| Squarepoint Ops LLC | 0.00% | New | 20,098 | $148K |
| Verition Fund Management LLC | 0.00% | New | 19,815 | $146K |
| Koa Wealth Management, LLC | 0.12% | New | 19,396 | $143K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -56.5% | 15,168 | $112K |
| Nuveen, LLC | 0.00% | — | 14,471 | $107K |
| Susquehanna International Group, LLP | 0.00% | New | 13,660 | $101K |
| Gsa Capital Partners LLP | 0.01% | New | 12,369 | $91K |
| Wealthedge Investment Advisors, LLC | 0.04% | New | 11,864 | $88K |
| Barclays PLC | 0.00% | Reduce -32.2% | 11,818 | $87K |
| Intech Investment Management LLC | 0.00% | New | 10,728 | $79K |
| Deutsche Bank AG | 0.00% | Add +102.0% | 8,762 | $65K |
| Rhumbline Advisers | 0.00% | Reduce -8.0% | 8,712 | $64K |
| Virtus Investment Advisers, LLC | 0.02% | New | 8,006 | $59K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.9% | 6,647 | $49K |
| Wells Fargo & Company | 0.00% | Add +2.3% | 5,977 | $44K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 5,511 | $41K |
| New York State Common Retirement Fund | 0.00% | New | 4,300 | $32K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 2,143 | $16K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +70.0% | 1,365 | $10K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 1,177 | $9K |
| Legal & General Group Plc | 0.00% | No change | 1,107 | $8K |
| California State Teachers Retirement System | 0.00% | No change | 832 | $6K |
| STRS Ohio | 0.00% | Reduce -66.7% | 700 | $5K |
| Royal Bank of Canada | 0.00% | Reduce -23.8% | 635 | $4K |
| Amalgamated Bank | 0.00% | No change | 384 | $3K |
| US Bancorp \de | 0.00% | New | 330 | $2K |
| Cwm, LLC | 0.00% | New | 137 | $1K |
| Sterling Capital Management LLC | 0.00% | Reduce -43.5% | 91 | $672 |
| GAMMA Investing LLC | 0.00% | New | 20 | $148 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 9 | $66 |
| True Wealth Design, LLC | 0.00% | New | 3 | $23 |
"% of holder's portfolio" is MBX's weight in each manager's 13F, not the share of MBX Biosciences Inc. the manager owns.