Milestone PharmaceuticalsMIST
13F holders, Q3 2025 (September 30)61holders +18
26new positions
7sold out
3famous investors
$2.00avg. 13F price*
At the end of Q3 2025, 61 institutions reported holding Milestone Pharmaceuticals Inc. (MIST) in their 13F filings, up 18 from Q2 2025. 26 opened new positions and 7 sold out. The largest holders were Adage Capital Partners Gp, L.L.C. ($14.0M), Propel Bio Management, LLC ($10.2M) and Orbimed Advisors LLC ($6.4M). 3 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Milestone Pharmaceuticals Inc.
- CUSIP
- 59935V107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 26 | $33.7M |
| Exits | 7 | $6.0M |
All 13F filers, Q2 2025 → Q3 2025: 25,479,829 shares bought and 3,159,074 shares sold, net +22,320,755 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 61 holders
| Adage Capital Partners Gp, L.L.C. | 0.02% | New | 6,976,000 | $14.0M |
| Propel Bio Management, LLC | 10.26% | Add +186.1% | 5,124,890 | $10.2M |
| Orbimed Advisors LLC | 0.15% | New | 3,221,828 | $6.4M |
| Morgan Stanley | 0.00% | Add +261.9% | 2,969,067 | $5.9M |
| Simplify Asset Management Inc. | 0.11% | Add +186.2% | 2,832,974 | $5.7M |
| RTW Investments, LP | 0.06% | No change | 2,506,102 | $5.0M |
| Pathstone Holdings, LLC | 0.01% | New | 1,000,000 | $2.0M |
| Sphera Funds Management LTD. | 0.39% | New | 820,000 | $1.6M |
| Toronto Dominion Bank | 0.00% | No change | 750,000 | $1.5M |
| Boxer Capital Management, LLC | 0.43% | New | 666,666 | $1.3M |
| Affinity Asset Advisors, LLC | 0.13% | New | 666,666 | $1.3M |
| Two Sigma Investments, LP | 0.00% | New | 666,551 | $1.3M |
| Lion Point Capital, LP | 7.48% | Add +20.0% | 658,553 | $1.3M |
| Citadel Advisors | 0.00% | New | 512,067 | $1.0M |
| Marshall Wace, LLP | 0.00% | New | 425,028 | $850K |
| Jane Street Group, LLC | 0.00% | Add +1179.2% | 408,492 | $817K |
| Millennium Management | 0.00% | New | 401,559 | $803K |
| UBS Group AG | 0.00% | Add +23.2% | 397,534 | $795K |
| Goldman Sachs Group Inc. | 0.00% | Add +198.5% | 356,567 | $713K |
| Susquehanna International Group, LLP | 0.00% | Add +305.2% | 256,772 | $514K |
| Two Sigma Advisers, LP | 0.00% | New | 234,041 | $468K |
| AMH Equity Ltd | 0.58% | New | 231,671 | $463K |
| Quadrature Capital Ltd | 0.01% | New | 223,470 | $448K |
| Guardian Wealth Advisors, LLC / NC | 0.03% | New | 210,200 | $420K |
| Aptus Capital Advisors, LLC | 0.00% | New | 210,200 | $420K |
| XTX Topco Ltd | 0.02% | Add +16.4% | 187,301 | $375K |
| Royal Bank of Canada | 0.00% | Add +302.8% | 143,400 | $287K |
| HRT Financial LP | 0.00% | New | 138,812 | $277K |
| Valeo Financial Advisors, LLC | 0.01% | No change | 130,699 | $261K |
| LPL Financial LLC | 0.00% | Add +762.4% | 95,300 | $191K |
| Gsa Capital Partners LLP | 0.01% | New | 78,747 | $157K |
| Cascades Capital Asset Management, LLC | 0.07% | Add +15.2% | 77,335 | $155K |
| Geode Capital Management, LLC | 0.00% | Add +312.2% | 74,022 | $148K |
| Simplex Trading, LLC | 0.00% | New | 66,920 | $133K |
| Northern Trust Corp. | 0.00% | Reduce -25.9% | 39,258 | $79K |
| Focus Partners Wealth | 0.00% | No change | 36,000 | $72K |
| Federation des caisses Desjardins du Quebec | 0.00% | Add +129.1% | 29,781 | $60K |
| Raymond James Financial Inc. | 0.00% | Reduce -38.5% | 26,600 | $53K |
| Safeguard Investment Advisory Group, LLC | 0.01% | No change | 25,044 | $50K |
| Mariner, LLC | 0.00% | Add +127.3% | 25,000 | $50K |
| Creative Planning | 0.00% | No change | 23,410 | $47K |
| State Street Corp. | 0.00% | Add +21.8% | 22,220 | $44K |
| Stephenson & Company, Inc. | 0.02% | New | 20,000 | $40K |
| National Bank of Canada | 0.00% | No change | 18,700 | $37K |
| Bay Rivers Group | 0.01% | Add +16.6% | 16,691 | $33K |
| Bank of America Corp. | 0.00% | Add +200550.0% | 16,052 | $32K |
| Beta Wealth Group, Inc. | 0.01% | No change | 14,127 | $28K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | New | 12,698 | $25K |
| Sapient Capital LLC | 0.00% | New | 12,200 | $25K |
| Jones Financial Companies LLLP | 0.00% | No change | 11,000 | $22K |
| Secure Asset Management, LLC | 0.00% | New | 10,000 | $21K |
| Taylor Financial Group, Inc. | 0.01% | No change | 10,000 | $20K |
| Journey Strategic Wealth LLC | 0.00% | Reduce -33.3% | 10,000 | $20K |
| Ancora Advisors LLC | 0.00% | No change | 10,000 | $20K |
| AQR Capital Management | 0.00% | New | 10,000 | $20K |
| Citigroup Inc. | 0.00% | New | 7,812 | $16K |
| Group One Trading LLC | 0.00% | Reduce -77.8% | 7,022 | $14K |
| US Bancorp \de | 0.00% | No change | 3,200 | $6K |
| Wealthspire Advisors, LLC | 0.00% | New | 1,129 | $2K |
| Arax Advisory Partners | 0.00% | New | 1,077 | $2K |
| SBI Securities Co., Ltd. | 0.00% | No change | 6 | $12 |
"% of holder's portfolio" is MIST's weight in each manager's 13F, not the share of Milestone Pharmaceuticals Inc. the manager owns.