Mineralys TherapeuticsMLYS

13F holders, Q4 2024 (December 31)
108holders +2
13new positions
14sold out
2famous investors
$12.31avg. 13F price*

At the end of Q4 2024, 108 institutions reported holding Mineralys Therapeutics Inc. (MLYS) in their 13F filings, up 2 from Q3 2024. 13 opened new positions and 14 sold out. The largest holders were Catalys Pacific, LLC ($106.4M), Samsara Biocapital, LLC ($62.5M) and Ra Capital Management, L.P. ($59.7M). 2 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Mineralys Therapeutics Inc.
CUSIP
603170101
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 92Q1 2024Q2 2024: 94Q2 2024Q3 2024: 106Q3 2024Q4 2024: 108Q4 2024Q1 2025: 149Q1 2025Q2 2025: 165Q2 2025Q3 2025: 193Q3 2025Q4 2025: 223Q4 2025Q1 2026: 215Q1 2026Q2 2026: 225Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions13$9.7M
Exits14$12.3M

All 13F filers, Q3 2024 → Q4 2024: 4,027,287 shares bought and 2,021,581 shares sold, net +2,005,706 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 108 holders

Catalys Pacific, LLC 91.82% No change 8,644,579 $106.4M
Samsara Biocapital, LLC 8.57% No change 5,074,916 $62.5M
Ra Capital Management, L.P. 0.80% No change 4,850,984 $59.7M
TCG Crossover Management, LLC 2.97% No change 2,470,265 $30.4M
BlackRock, Inc. 0.00% Reduce -0.3% 2,138,522 $26.3M
SR One Capital Management, LP 6.05% No change 2,016,822 $24.8M
Franklin Resources Inc. 0.01% Add +0.0% 1,745,597 $21.5M
Orbimed Advisors LLC 0.41% Reduce -19.5% 1,611,637 $19.8M
Vanguard Group Inc. 0.00% Add +5.0% 1,432,042 $17.6M
Laurion Capital Management LP 1.11% No change 1,412,389 $17.4M
Adams Street Partners LLC 12.33% Reduce -26.3% 1,129,807 $13.9M
Millennium Management 0.01% Add +1015.8% 1,101,674 $13.6M
Jennison Associates LLC 0.01% Add +55.4% 1,082,006 $13.3M
Caligan Partners LP 3.15% Add +3.1% 1,011,155 $12.4M
Integral Health Asset Management, LLC 0.95% Add +145.8% 875,000 $10.8M
American Century Companies Inc. 0.01% Reduce -8.9% 848,630 $10.4M
ADAR1 Capital Management, LLC 2.21% Add +15.4% 841,541 $10.4M
Boothbay Fund Management, LLC 0.25% Add +7.3% 650,023 $8.0M
Nantahala Capital Management, LLC 0.54% No change 632,506 $7.8M
Geode Capital Management, LLC 0.00% Reduce -0.1% 620,033 $7.6M
Morgan Stanley 0.00% Add +14.3% 589,444 $7.3M
State Street Corp. 0.00% Add +4.3% 504,533 $6.2M
JPMorgan Chase & Co. 0.00% Add +2251.5% 503,590 $6.2M
Stempoint Capital LP 1.24% New 400,101 $4.9M
Sectoral Asset Management Inc. 3.13% Add +15.6% 380,883 $4.7M
Affinity Asset Advisors, LLC 0.73% No change 350,000 $4.3M
Ikarian Capital, LLC 1.17% Add +84.7% 332,390 $4.1M
Candriam S.C.A. 0.02% New 305,272 $3.8M
FMR LLC 0.00% Add +0.1% 304,184 $3.7M
Northern Trust Corp. 0.00% Add +0.7% 246,113 $3.0M
Charles Schwab Investment Management Inc. 0.00% Add +0.6% 214,906 $2.6M
Sphera Funds Management LTD. 0.43% Reduce -30.0% 190,672 $2.3M
DAFNA Capital Management LLC 0.46% No change 146,500 $1.8M
Pale Fire Capital SE 0.39% No change 136,897 $1.7M
Prudential Financial Inc. 0.00% Add +85.7% 125,650 $1.5M
Renaissance Technologies 0.00% Add +15.1% 119,500 $1.5M
Goldman Sachs Group Inc. 0.00% Add +25.1% 111,915 $1.4M
Bank of America Corp. 0.00% Add +12.0% 107,703 $1.3M
Polar Asset Management Partners Inc. 0.02% Add +144.7% 99,100 $1.2M
Wellington Management Group LLP 0.00% Add +43.0% 91,529 $1.1M
Tema ETFs LLC 0.46% — 89,529 $1.1M
NEOS Investment Management LLC 0.03% Reduce -27.5% 89,529 $1.1M
Lion Point Capital, LP 5.09% No change 79,000 $972K
Nuveen Asset Management, LLC 0.00% No change 67,877 $836K
Bank of New York Mellon Corp 0.00% Add +2.7% 65,318 $804K
UBS Group AG 0.00% Add +203.6% 48,885 $602K
Barclays PLC 0.00% Add +21.4% 46,396 $571K
Rhumbline Advisers 0.00% Add +1.7% 40,556 $499K
Alps Advisors Inc. 0.00% Add +5.2% 40,248 $495K
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.01% Reduce -9.7% 28,068 $346K
STRS Ohio 0.00% No change 26,900 $331K
Deutsche Bank AG 0.00% Add +62.3% 26,732 $329K
Wells Fargo & Company 0.00% Add +19.1% 23,714 $292K
Citigroup Inc. 0.00% Add +6.3% 23,364 $288K
Alliancebernstein L.P. 0.00% Add +0.3% 23,024 $283K
SG Americas Securities, LLC 0.00% Add +119.0% 19,961 $246K
Balyasny Asset Management L.P. 0.00% New 17,786 $219K
MetLife Investment Management, LLC 0.00% No change 17,124 $211K
Letko, Brosseau & Associates Inc. 0.00% Add +44.7% 16,500 $203K
Bellevue Group AG 0.00% No change 16,499 $203K
Dimensional Fund Advisors LP 0.00% New 16,412 $202K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +4.4% 16,383 $202K
Federated Hermes, Inc. 0.00% Reduce -7.9% 15,516 $191K
AlphaQuest LLC 0.02% Add +2637.8% 15,222 $187K
Martingale Asset Management L P 0.00% No change 14,965 $184K
Corebridge Financial, Inc. 0.00% Reduce -7.0% 14,197 $175K
EntryPoint Capital, LLC 0.06% New 12,487 $154K
Susquehanna International Group, LLP 0.00% New 12,346 $152K
Manufacturers Life Insurance Company, The 0.00% Reduce -2.9% 11,797 $145K
T. Rowe Price Associates Inc. 0.00% New 11,715 $145K
CreativeOne Wealth, LLC 0.00% No change 10,750 $132K
China Universal Asset Management Co., Ltd. 0.01% Add +10.3% 10,553 $130K
ProShare Advisors LLC 0.00% New 10,405 $128K
New York State Common Retirement Fund 0.00% No change 7,764 $96K
Police & Firemen's Retirement System of New Jersey 0.00% — 7,136 $88K
Virtus Advisers, LLC 0.03% Reduce -19.6% 5,842 $72K
Cwm, LLC 0.00% Add +0.3% 5,237 $64K
BNP Paribas Financial Markets 0.00% New 3,895 $48K
Royal Bank of Canada 0.00% Add +23.0% 3,535 $43K
Ameritas Investment Partners, Inc. 0.00% No change 2,798 $34K
Legal & General Group Plc 0.00% No change 2,582 $32K
PNC Financial Services Group, Inc. 0.00% Reduce -1.2% 2,185 $27K
California State Teachers Retirement System 0.00% No change 2,069 $25K
Smartleaf Asset Management LLC 0.00% Add +23.9% 1,905 $24K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -7.8% 1,658 $21K
GeoWealth Management, LLC 0.00% No change 1,439 $18K
Meeder Asset Management Inc. 0.00% New 1,338 $16K
GF Fund Management Co. LTD. 0.00% — 1,045 $13K
Tower Research Capital LLC (TRC) 0.00% Reduce -62.4% 1,005 $12K
Sterling Capital Management LLC 0.00% Add +839.0% 723 $9K
Amalgamated Bank 0.00% No change 682 $8K
Comerica Bank 0.00% No change 644 $8K
SBI Securities Co., Ltd. 0.00% — 400 $5K
Simplex Trading, LLC 0.00% Add +10.9% 337 $4K
MassMutual Private Wealth & Trust, FSB 0.00% No change 319 $4K
Daiwa Securities Group Inc. 0.00% No change 152 $2K
Quadrant Capital Group LLC 0.00% No change 129 $2K
Arax Advisory Partners 0.00% No change 108 $1K
Rothschild Investment LLC 0.00% Add +250.0% 105 $1K
Nisa Investment Advisors, LLC 0.00% Add +1960.0% 103 $1K
GAMMA Investing LLC 0.00% Add +21.3% 91 $1K
Creative Planning 0.00% New 77 $948
Versant Capital Management, Inc 0.00% Reduce -15.9% 53 $652
Private Wealth Management Group, LLC 0.00% No change 50 $616
Allworth Financial LP 0.00% Reduce -79.0% 28 $286
Parallel Advisors, LLC 0.00% No change 22 $271
US Bancorp \de 0.00% New 18 $222
Farther Finance Advisors, LLC 0.00% No change 17 $209

"% of holder's portfolio" is MLYS's weight in each manager's 13F, not the share of Mineralys Therapeutics Inc. the manager owns.